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Items: 36

1.

A GWAS meta-analysis from 5 population-based cohorts implicates ion channel genes in the pathogenesis of irritable bowel syndrome.

Bonfiglio F, Henström M, Nag A, Hadizadeh F, Zheng T, Cenit MC, Tigchelaar E, Williams F, Reznichenko A, Ek WE, Rivera NV, Homuth G, Aghdassi AA, Kacprowski T, Männikkö M, Karhunen V, Bujanda L, Rafter J, Wijmenga C, Ronkainen J, Hysi P, Zhernakova A, D'Amato M.

Neurogastroenterol Motil. 2018 Sep;30(9):e13358. doi: 10.1111/nmo.13358. Epub 2018 Apr 19.

PMID:
29673008
2.

Influence of gut microbiota on neuropsychiatric disorders.

Cenit MC, Sanz Y, Codoñer-Franch P.

World J Gastroenterol. 2017 Aug 14;23(30):5486-5498. doi: 10.3748/wjg.v23.i30.5486. Review.

3.

Gut microbiota and attention deficit hyperactivity disorder: new perspectives for a challenging condition.

Cenit MC, Nuevo IC, Codoñer-Franch P, Dinan TG, Sanz Y.

Eur Child Adolesc Psychiatry. 2017 Sep;26(9):1081-1092. doi: 10.1007/s00787-017-0969-z. Epub 2017 Mar 13. Review.

PMID:
28289903
4.

The effect of host genetics on the gut microbiome.

Bonder MJ, Kurilshikov A, Tigchelaar EF, Mujagic Z, Imhann F, Vila AV, Deelen P, Vatanen T, Schirmer M, Smeekens SP, Zhernakova DV, Jankipersadsing SA, Jaeger M, Oosting M, Cenit MC, Masclee AA, Swertz MA, Li Y, Kumar V, Joosten L, Harmsen H, Weersma RK, Franke L, Hofker MH, Xavier RJ, Jonkers D, Netea MG, Wijmenga C, Fu J, Zhernakova A.

Nat Genet. 2016 Nov;48(11):1407-1412. doi: 10.1038/ng.3663. Epub 2016 Oct 3.

PMID:
27694959
5.

Gut Microbiota and Risk of Developing Celiac Disease.

Cenit MC, Codoñer-Franch P, Sanz Y.

J Clin Gastroenterol. 2016 Nov/Dec;50 Suppl 2, Proceedings from the 8th Probiotics, Prebiotics & New Foods for Microbiota and Human Health meeting held in Rome, Italy on September 13-15, 2015:S148-S152. Review.

PMID:
27741161
6.

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity.

Zhernakova A, Kurilshikov A, Bonder MJ, Tigchelaar EF, Schirmer M, Vatanen T, Mujagic Z, Vila AV, Falony G, Vieira-Silva S, Wang J, Imhann F, Brandsma E, Jankipersadsing SA, Joossens M, Cenit MC, Deelen P, Swertz MA; LifeLines cohort study, Weersma RK, Feskens EJ, Netea MG, Gevers D, Jonkers D, Franke L, Aulchenko YS, Huttenhower C, Raes J, Hofker MH, Xavier RJ, Wijmenga C, Fu J.

Science. 2016 Apr 29;352(6285):565-9. doi: 10.1126/science.aad3369. Epub 2016 Apr 28.

7.

The influence of a short-term gluten-free diet on the human gut microbiome.

Bonder MJ, Tigchelaar EF, Cai X, Trynka G, Cenit MC, Hrdlickova B, Zhong H, Vatanen T, Gevers D, Wijmenga C, Wang Y, Zhernakova A.

Genome Med. 2016 Apr 21;8(1):45. doi: 10.1186/s13073-016-0295-y.

8.

Proton pump inhibitors affect the gut microbiome.

Imhann F, Bonder MJ, Vich Vila A, Fu J, Mujagic Z, Vork L, Tigchelaar EF, Jankipersadsing SA, Cenit MC, Harmsen HJ, Dijkstra G, Franke L, Xavier RJ, Jonkers D, Wijmenga C, Weersma RK, Zhernakova A.

Gut. 2016 May;65(5):740-8. doi: 10.1136/gutjnl-2015-310376. Epub 2015 Dec 9.

9.

The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids.

Fu J, Bonder MJ, Cenit MC, Tigchelaar EF, Maatman A, Dekens JA, Brandsma E, Marczynska J, Imhann F, Weersma RK, Franke L, Poon TW, Xavier RJ, Gevers D, Hofker MH, Wijmenga C, Zhernakova A.

Circ Res. 2015 Oct 9;117(9):817-24. doi: 10.1161/CIRCRESAHA.115.306807. Epub 2015 Sep 10.

10.

Cohort profile: LifeLines DEEP, a prospective, general population cohort study in the northern Netherlands: study design and baseline characteristics.

Tigchelaar EF, Zhernakova A, Dekens JA, Hermes G, Baranska A, Mujagic Z, Swertz MA, Muñoz AM, Deelen P, Cénit MC, Franke L, Scholtens S, Stolk RP, Wijmenga C, Feskens EJ.

BMJ Open. 2015 Aug 28;5(8):e006772. doi: 10.1136/bmjopen-2014-006772.

11.

Intestinal Microbiota and Celiac Disease: Cause, Consequence or Co-Evolution?

Cenit MC, Olivares M, Codoñer-Franch P, Sanz Y.

Nutrients. 2015 Aug 17;7(8):6900-23. doi: 10.3390/nu7085314. Review.

12.

The genetics of celiac disease: A comprehensive review of clinical implications.

Dieli-Crimi R, Cénit MC, Núñez C.

J Autoimmun. 2015 Nov;64:26-41. doi: 10.1016/j.jaut.2015.07.003. Epub 2015 Jul 17. Review.

PMID:
26194613
13.

Analysis of ancestral and functionally relevant CD5 variants in systemic lupus erythematosus patients.

Cenit MC, Martínez-Florensa M, Consuegra M, Bonet L, Carnero-Montoro E, Armiger N, Caballero-Baños M, Arias MT, Benitez D, Ortego-Centeno N, de Ramón E, Sabio JM, García-Hernández FJ, Tolosa C, Suárez A, González-Gay MA, Bosch E, Martín J, Lozano F.

PLoS One. 2014 Nov 17;9(11):e113090. doi: 10.1371/journal.pone.0113090. eCollection 2014.

14.

Rapidly expanding knowledge on the role of the gut microbiome in health and disease.

Cénit MC, Matzaraki V, Tigchelaar EF, Zhernakova A.

Biochim Biophys Acta. 2014 Oct;1842(10):1981-1992. doi: 10.1016/j.bbadis.2014.05.023. Epub 2014 Jun 2. Review.

15.

HLA alleles as biomarkers of high-titre neutralising antibodies to interferon-β therapy in multiple sclerosis.

Núñez C, Cénit MC, Alvarez-Lafuente R, Río J, Fernández-Arquero M, Arroyo R, Montalbán X, Fernández O, Oliver-Martos B, Leyva L, Comabella M, Urcelay E.

J Med Genet. 2014 Jun;51(6):395-400. doi: 10.1136/jmedgenet-2014-102348. Epub 2014 Apr 19.

PMID:
24748646
16.

No evidence of association between common autoimmunity STAT4 and IL23R risk polymorphisms and non-anterior uveitis.

Cénit MC, Márquez A, Cordero-Coma M, Gorroño-Echebarría MB, Fonollosa A, Adán A, Martínez-Berriotxoa A, Díaz Valle D, Pato E, Blanco R, Cañal J, Díaz-Llopis M, García Serrano JL, de Ramón E, Del Rio MJ, Martín-Villa JM, Molins B, Ortego-Centeno N, Martín J.

PLoS One. 2013 Nov 29;8(11):e72892. doi: 10.1371/journal.pone.0072892. eCollection 2013.

17.

Two functional variants of IRF5 influence the development of macular edema in patients with non-anterior uveitis.

Márquez A, Cénit MC, Cordero-Coma M, Ortego-Centeno N, Adán A, Fonollosa A, Díaz Valle D, Pato E, Blanco R, Cañal J, Díaz-Llopis M, de Ramón E, Del Rio MJ, García Serrano JL, Artaraz J, Martín-Villa JM, Llorenç V, Gorroño-Echebarría MB, Martín J.

PLoS One. 2013 Oct 7;8(10):e76777. doi: 10.1371/journal.pone.0076777. eCollection 2013.

18.

Evaluation of the IL2/IL21, IL2RA and IL2RB genetic variants influence on the endogenous non-anterior uveitis genetic predisposition.

Cénit MC, Márquez A, Cordero-Coma M, Fonollosa A, Adán A, Martínez-Berriotxoa A, Llorenç V, Díaz Valle D, Blanco R, Cañal J, Díaz-Llopis M, García Serrano JL, de Ramón E, del Rio MJ, Begoña Gorroño-Echebarría M, Martín-Villa JM, Ortego-Centeno N, Martín J.

BMC Med Genet. 2013 May 15;14:52. doi: 10.1186/1471-2350-14-52.

19.

Lack of association between the protein tyrosine phosphatase non-receptor type 22 R263Q and R620W functional genetic variants and endogenous non-anterior uveitis.

Cénit MC, Márquez A, Cordero-Coma M, Fonollosa A, Llorenç V, Artaraz J, Díaz Valle D, Blanco R, Cañal J, Salom D, García Serrano JL, de Ramón E, José del Rio M, Gorroño-Echebarría MB, Martín-Villa JM, Molins B, Ortego-Centeno N, Martín J.

Mol Vis. 2013;19:638-43. Epub 2013 Mar 20.

20.

New insight on the Xq28 association with systemic sclerosis.

Carmona FD, Cénit MC, Diaz-Gallo LM, Broen JC, Simeón CP, Carreira PE, Callejas-Rubio JL, Fonollosa V, López-Longo FJ, González-Gay MA, Hunzelmann N, Riemekasten G, Witte T, Kreuter A, Distler JH, Madhok R, Shiels P, van Laar JM, Schuerwegh AJ, Vonk MC, Voskuyl AE, Fonseca C, Denton CP, Herrick A, Worthington J, Arnett FC, Tan FK, Assassi S, Radstake TR, Mayes MD, Martín J; Spanish Scleroderma Group.

Ann Rheum Dis. 2013 Dec;72(12):2032-8. doi: 10.1136/annrheumdis-2012-202742. Epub 2013 Feb 26.

21.

Influence of the STAT3 genetic variants in the susceptibility to psoriatic arthritis and Behcet's disease.

Cénit MC, Ortego-Centeno N, Raya E, Callejas JL, García-Hernandez FJ, Castillo-Palma MJ, Fernandez-Sueiro JL, Magro C, Solans R, Castañeda S, Camps M, Hidalgo A, Espinosa G, González-Gay MA, González-Escribano MF, Martín J.

Hum Immunol. 2013 Feb;74(2):230-3. doi: 10.1016/j.humimm.2012.10.019. Epub 2012 Nov 2.

PMID:
23127549
22.

Influence of the IL6 gene in susceptibility to systemic sclerosis.

Cénit MC, Simeón CP, Vonk MC, Callejas-Rubio JL, Espinosa G, Carreira P, Blanco FJ, Narvaez J, Tolosa C, Román-Ivorra JA, Gómez-García I, García-Hernández FJ, Gallego M, García-Portales R, Egurbide MV, Fonollosa V, García de la Peña P, López-Longo FJ, González-Gay MA; Spanish Scleroderma Group, Hesselstrand R, Riemekasten G, Witte T, Voskuyl AE, Schuerwegh AJ, Madhok R, Fonseca C, Denton C, Nordin A, Palm Ø, van Laar JM, Hunzelmann N, Distler JH, Kreuter A, Herrick A, Worthington J, Koeleman BP, Radstake TR, Martín J.

J Rheumatol. 2012 Dec;39(12):2294-302. doi: 10.3899/jrheum.120506. Epub 2012 Oct 1.

PMID:
23027890
23.

No evidence of association between functional polymorphisms located within IL6R and IL6ST genes and systemic sclerosis.

Cénit MC, Simeón CP, Fonollosa V, Espinosa G, Beltrán E, Sáez-Comet L, Vicente-Rabaneda E, García-Hernández FJ, Martínez-Estupiñán L, Rodríguez-Carballeira M, Hernández V, de la Peña PG, Fernández-Castro M, Narváez FJ, Pros A, Gallego M, Ríos-Fernández R, Camps MT, Fernández-Nebro A, Egurbide MV, Carreira P, González-Gay MA, Martín J; Spanish Scleroderma Group.

Tissue Antigens. 2012 Sep;80(3):254-8. doi: 10.1111/j.1399-0039.2012.01915.x. Epub 2012 Jun 29.

PMID:
22742541
24.

DRB1*03:01 haplotypes: differential contribution to multiple sclerosis risk and specific association with the presence of intrathecal IgM bands.

de la Concha EG, Cavanillas ML, Cénit MC, Urcelay E, Arroyo R, Fernández Ó, Álvarez-Cermeño JC, Leyva L, Villar LM, Núñez C.

PLoS One. 2012;7(2):e31018. doi: 10.1371/journal.pone.0031018. Epub 2012 Feb 17.

25.

Replication of top markers of a genome-wide association study in multiple sclerosis in Spain.

Cavanillas ML, Fernández O, Comabella M, Alcina A, Fedetz M, Izquierdo G, Lucas M, Cénit MC, Arroyo R, Vandenbroeck K, Alloza I, García-Barcina M, Antigüedad A, Leyva L, Gómez CL, Olascoaga J, Otaegui D, Blanco Y, Saiz A, Montalbán X, Matesanz F, Urcelay E.

Genes Immun. 2011 Mar;12(2):110-5. doi: 10.1038/gene.2010.52. Epub 2010 Oct 14.

PMID:
20944657
26.

Validation of IRF5 as multiple sclerosis risk gene: putative role in interferon beta therapy and human herpes virus-6 infection.

Vandenbroeck K, Alloza I, Swaminathan B, Antigüedad A, Otaegui D, Olascoaga J, Barcina MG, de las Heras V, Bartolomé M, Fernández-Arquero M, Arroyo R, Alvarez-Lafuente R, Cénit MC, Urcelay E.

Genes Immun. 2011 Jan;12(1):40-5. doi: 10.1038/gene.2010.46. Epub 2010 Sep 23.

PMID:
20861862
27.

MSH5 is not a genetic predisposing factor for immunoglobulin A deficiency but marks the HLA-DRB1*0102 subgroup carrying susceptibility.

Pozo ND, Medrano LM, Cénit MC, Fernández-Arquero M, Ferreira A, García-Rodríguez MC, de la Concha EG, Urcelay E, Núñez C.

Hum Immunol. 2010 Sep;71(9):861-4. doi: 10.1016/j.humimm.2010.06.007. Epub 2010 Jun 11.

PMID:
20542071
28.

The autoimmune disease-associated KIF5A, CD226 and SH2B3 gene variants confer susceptibility for multiple sclerosis.

Alcina A, Vandenbroeck K, Otaegui D, Saiz A, Gonzalez JR, Fernandez O, Cavanillas ML, Cénit MC, Arroyo R, Alloza I, García-Barcina M, Antigüedad A, Leyva L, Izquierdo G, Lucas M, Fedetz M, Pinto-Medel MJ, Olascoaga J, Blanco Y, Comabella M, Montalban X, Urcelay E, Matesanz F.

Genes Immun. 2010 Jul;11(5):439-45. doi: 10.1038/gene.2010.30. Epub 2010 May 27.

PMID:
20508602
29.

Validation of the CD6 and TNFRSF1A loci as risk factors for multiple sclerosis in Spain.

Swaminathan B, Matesanz F, Cavanillas ML, Alloza I, Otaegui D, Olascoaga J, Cénit MC, de las Heras V, Barcina MG, Arroyo R, Alcina A, Fernandez O, Antigüedad A, Urcelay E, Vandenbroeck K.

J Neuroimmunol. 2010 Jun;223(1-2):100-3. doi: 10.1016/j.jneuroim.2010.03.020. Epub 2010 Apr 28.

PMID:
20430450
30.

STAT3 locus in inflammatory bowel disease and multiple sclerosis susceptibility.

Cénit MC, Alcina A, Márquez A, Mendoza JL, Díaz-Rubio M, de las Heras V, Izquierdo G, Arroyo R, Fernández O, de la Concha EG, Matesanz F, Urcelay E.

Genes Immun. 2010 Apr;11(3):264-8. doi: 10.1038/gene.2010.10. Epub 2010 Mar 4.

PMID:
20200543
31.

Effect of BSN-MST1 locus on inflammatory bowel disease and multiple sclerosis susceptibility.

Márquez A, Cénit MC, Núñez C, Mendoza JL, Taxonera C, Díaz-Rubio M, Bartolomé M, Arroyo R, Fernández-Arquero M, de la Concha EG, Urcelay E.

Genes Immun. 2009 Oct;10(7):631-5. doi: 10.1038/gene.2009.56. Epub 2009 Aug 6.

PMID:
19657358
32.

HLA class I and II alleles and response to treatment with interferon-beta in relapsing-remitting multiple sclerosis.

Comabella M, Fernández-Arquero M, Río J, Guinea A, Fernández M, Cenit MC, de la Concha EG, Montalban X.

J Neuroimmunol. 2009 May 29;210(1-2):116-9. doi: 10.1016/j.jneuroim.2009.01.012. Epub 2009 Apr 5. Erratum in: J Neuroimmunol. 2009 Sep 29;214(1-2):132.

PMID:
19349081
33.

Chromosomal region 16p13: further evidence of increased predisposition to immune diseases.

Martínez A, Perdigones N, Cénit MC, Espino L, Varadé J, Lamas JR, Santiago JL, Fernández-Arquero M, de la Calle H, Arroyo R, de la Concha EG, Fernández-Gutiérrez B, Urcelay E.

Ann Rheum Dis. 2010 Jan;69(1):309-11. doi: 10.1136/ard.2008.098376. Erratum in: Ann Rheum Dis. 2011 Jan;70(1):240.

PMID:
19221398
34.

Association of the STAT4 gene with increased susceptibility for some immune-mediated diseases.

Martínez A, Varadé J, Márquez A, Cénit MC, Espino L, Perdigones N, Santiago JL, Fernández-Arquero M, de la Calle H, Arroyo R, Mendoza JL, Fernández-Gutiérrez B, de la Concha EG, Urcelay E.

Arthritis Rheum. 2008 Sep;58(9):2598-602. doi: 10.1002/art.23792.

35.

IL23R: a susceptibility locus for celiac disease and multiple sclerosis?

Núñez C, Dema B, Cénit MC, Polanco I, Maluenda C, Arroyo R, de las Heras V, Bartolomé M, de la Concha EG, Urcelay E, Martínez A.

Genes Immun. 2008 Jun;9(4):289-93. doi: 10.1038/gene.2008.16. Epub 2008 Mar 27.

PMID:
18368064
36.

IFIH1-GCA-KCNH7 locus: influence on multiple sclerosis risk.

Martínez A, Santiago JL, Cénit MC, de Las Heras V, de la Calle H, Fernández-Arquero M, Arroyo R, de la Concha EG, Urcelay E.

Eur J Hum Genet. 2008 Jul;16(7):861-4. doi: 10.1038/ejhg.2008.16. Epub 2008 Feb 20.

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