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Items: 1 to 50 of 78

1.

In Vitro Tests for Aerosol Deposition. VI: Realistic Testing with Different Mouth-Throat Models and In Vitro-In Vivo Correlations for a Dry Powder Inhaler, Metered Dose Inhaler, and Soft Mist Inhaler.

Wei X, Hindle M, Kaviratna A, Huynh BK, Delvadia RR, Sandell D, Byron PR.

J Aerosol Med Pulm Drug Deliv. 2018 Jun 7. doi: 10.1089/jamp.2018.1454. [Epub ahead of print]

PMID:
29878859
2.

In Vitro Tests for Aerosol Deposition. V: Using Realistic Testing to Estimate Variations in Aerosol Properties at the Trachea.

Wei X, Hindle M, Delvadia RR, Byron PR.

J Aerosol Med Pulm Drug Deliv. 2017 Oct;30(5):339-348. doi: 10.1089/jamp.2016.1349. Epub 2017 Mar 23.

PMID:
28332899
3.

In Vitro Tests for Aerosol Deposition. IV: Simulating Variations in Human Breath Profiles for Realistic DPI Testing.

Delvadia RR, Wei X, Longest PW, Venitz J, Byron PR.

J Aerosol Med Pulm Drug Deliv. 2016 Apr;29(2):196-206. doi: 10.1089/jamp.2015.1215. Epub 2015 Oct 8.

4.

Iloprost reverses established fibrosis in experimental right ventricular failure.

Gomez-Arroyo J, Sakagami M, Syed AA, Farkas L, Van Tassell B, Kraskauskas D, Mizuno S, Abbate A, Bogaard HJ, Byron PR, Voelkel NF.

Eur Respir J. 2015 Feb;45(2):449-62. doi: 10.1183/09031936.00188013. Epub 2014 Sep 26.

5.

Tobramycin disposition in the rat lung following airway administration.

Li M, Byron PR.

J Pharmacol Exp Ther. 2013 Nov;347(2):318-24. doi: 10.1124/jpet.113.207415. Epub 2013 Sep 5.

PMID:
24008335
6.

In vitro tests for aerosol deposition. III: effect of inhaler insertion angle on aerosol deposition.

Delvadia RR, Longest PW, Hindle M, Byron PR.

J Aerosol Med Pulm Drug Deliv. 2013 Jun;26(3):145-56. doi: 10.1089/jamp.2012.0989. Epub 2012 Oct 1.

PMID:
23025452
7.

In vitro tests for aerosol deposition II: IVIVCs for different dry powder inhalers in normal adults.

Delvadia R, Hindle M, Longest PW, Byron PR.

J Aerosol Med Pulm Drug Deliv. 2013 Jun;26(3):138-44. doi: 10.1089/jamp.2012.0975. Epub 2012 Sep 4.

PMID:
22947131
8.

In vitro tests for aerosol deposition. I: Scaling a physical model of the upper airways to predict drug deposition variation in normal humans.

Delvadia RR, Longest PW, Byron PR.

J Aerosol Med Pulm Drug Deliv. 2012 Feb;25(1):32-40. doi: 10.1089/jamp.2011.0905. Epub 2011 Nov 9.

PMID:
22070526
9.

In vivo-in vitro correlations: predicting pulmonary drug deposition from pharmaceutical aerosols.

Byron PR, Hindle M, Lange CF, Longest PW, McRobbie D, Oldham MJ, Olsson B, Thiel CG, Wachtel H, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2010 Dec;23 Suppl 2:S59-69. doi: 10.1089/jamp.2010.0846. Review.

PMID:
21133801
10.

Calibration of the modified Electrical Low-Pressure Impactor (ELPI) for use with pressurized pharmaceutical aerosols.

Kotian R, Peart J, Bryner J, Byron PR.

J Aerosol Med Pulm Drug Deliv. 2009 Mar;22(1):55-65. doi: 10.1089/jamp.2008.0683.

PMID:
18954291
11.

Cascade impactor practice for a high dose dry powder inhaler at 90 L/min: NGI versus modified 6-stage and 8-stage ACI.

Kamiya A, Sakagami M, Byron PR.

J Pharm Sci. 2009 Mar;98(3):1028-39. doi: 10.1002/jps.21501.

PMID:
18661538
12.

Product Quality Research Institute evaluation of cascade impactor profiles of pharmaceutical aerosols. Part 3. Final report on a statistical procedure for determining equivalence.

Christopher D, Adams W, Amann A, Bertha C, Byron PR, Doub W, Dunbar C, Hauck W, Lyapustina S, Mitchell J, Morgan B, Nichols S, Pan Z, Singh GJ, Tougas T, Tsong Y, Wolff R, Wyka B.

AAPS PharmSciTech. 2007 Nov 2;8(4):E90. doi: 10.1208/pt0804090.

13.

Respiratory Drug Delivery Europe 2007.

Byron PR, Dalby RN, Peart J.

Expert Rev Respir Med. 2007 Aug;1(1):39-41. doi: 10.1586/17476348.1.1.39. No abstract available.

PMID:
20477264
14.

Insulin self-association: effects on lung disposition kinetics in the airways of the isolated perfused rat lung (IPRL).

Pang Y, Sakagami M, Byron PR.

Pharm Res. 2007 Sep;24(9):1636-44. Epub 2007 May 3.

PMID:
17476466
15.

Inhaling medicines: delivering drugs to the body through the lungs.

Patton JS, Byron PR.

Nat Rev Drug Discov. 2007 Jan;6(1):67-74. Review.

PMID:
17195033
16.

Stability and characterization of perphenazine aerosols generated using the capillary aerosol generator.

Li X, Blondino FE, Hindle M, Soine WH, Byron PR.

Int J Pharm. 2005 Oct 13;303(1-2):113-24.

PMID:
16139453
17.

Drug delivery devices: issues in drug development.

Byron PR.

Proc Am Thorac Soc. 2004;1(4):321-8. Review.

PMID:
16113453
18.

The pharmacokinetics of pulmonary insulin in the in vitro isolated perfused rat lung: implications of metabolism and regional deposition.

Pang Y, Sakagami M, Byron PR.

Eur J Pharm Sci. 2005 Jul-Aug;25(4-5):369-78. Epub 2005 Apr 26.

PMID:
15979534
19.
20.
21.
22.

Effect of energy on propylene glycol aerosols using the capillary aerosol generator.

Shen X, Hindle M, Byron PR.

Int J Pharm. 2004 May 4;275(1-2):249-58.

PMID:
15081155
23.
24.

Control of particle size by coagulation of novel condensation aerosols in reservoir chambers.

Hong JN, Hindle M, Byron PR.

J Aerosol Med. 2002 Winter;15(4):359-68.

PMID:
12581502
25.
26.

Physiochemical and pharmacological characterization of a Delta(9)-THC aerosol generated by a metered dose inhaler.

Wilson DM, Peart J, Martin BR, Bridgen DT, Byron PR, Lichtman AH.

Drug Alcohol Depend. 2002 Aug 1;67(3):259-67.

PMID:
12127197
27.
28.
29.

Physical characterization of large porous particles for inhalation.

Gupta R, Byron PR.

Pharm Res. 2000 Nov;17(11):1437-8. No abstract available.

PMID:
11205740
30.

A stability-indicating HPLC assay method for budesonide.

Hou S, Hindle M, Byron PR.

J Pharm Biomed Anal. 2001 Jan;24(3):371-80.

PMID:
11199216
31.

Polystyrene microsphere spray standards based on CFC-free inhaler technology.

Vervaet C, Byron PR.

J Aerosol Med. 2000 Summer;13(2):105-15.

PMID:
11010591
32.

Pharmacological evaluation of aerosolized cannabinoids in mice.

Lichtman AH, Peart J, Poklis JL, Bridgen DT, Razdan RK, Wilson DM, Poklis A, Meng Y, Byron PR, Martin BR.

Eur J Pharmacol. 2000 Jul 7;399(2-3):141-9.

PMID:
10884513
33.

Drug-surfactant-propellant interactions in HFA-formulations.

Vervaet C, Byron PR.

Int J Pharm. 1999 Sep 10;186(1):13-30. Review.

PMID:
10469920
36.

Surfactant dissolution and water solubilization in chlorine-free liquified gas propellants.

Blondino FE, Byron PR.

Drug Dev Ind Pharm. 1998 Oct;24(10):935-45.

PMID:
9876548
38.

United States Pharmacopeia recommendations for the testing of inhalers.

Byron PR.

J Aerosol Med. 1998;11 Suppl 1:S11-12. No abstract available.

PMID:
10180721
39.
40.

Performance characteristics of pressurized metered dose inhalers in vitro.

Byron PR.

J Aerosol Med. 1997;10 Suppl 1:S3-6. No abstract available.

PMID:
10165120
42.

The quantitative determination of aspirin and its degradation products in a model solution aerosol.

Blondino FE, Byron PR.

J Pharm Biomed Anal. 1995 Feb;13(2):111-9.

PMID:
7766717
43.

Dosing reproducibility from experimental albuterol suspension metered-dose inhalers.

Byron PR.

Pharm Res. 1994 Apr;11(4):580-4. No abstract available.

PMID:
8058620
45.

Drug delivery via the respiratory tract.

Byron PR, Patton JS.

J Aerosol Med. 1994;7(1):49-75.

PMID:
10147058
46.

Validation of an improved Wood's rotating disk dissolution apparatus.

Jashnani RN, Byron PR, Dalby RN.

J Pharm Sci. 1993 Jun;82(6):670-1. No abstract available.

PMID:
8331547
47.

Preparation, characterization, and dissolution kinetics of two novel albuterol salts.

Jashnani RN, Dalby RN, Byron PR.

J Pharm Sci. 1993 Jun;82(6):613-6.

PMID:
8331536
48.

Axial ratio measurements for early detection of crystal growth in suspension-type metered dose inhalers.

Phillips EM, Byron PR, Dalby RN.

Pharm Res. 1993 Mar;10(3):454-6. No abstract available.

PMID:
8464823
49.

Determination of drug solubility in aerosol propellants.

Dalby RN, Phillips EM, Byron PR.

Pharm Res. 1991 Sep;8(9):1206-9. No abstract available.

PMID:
1788170
50.

Optimized inhalation aerosols. II. Inertial testing methods for particle size analysis of pressurized inhalers.

Phillips EM, Byron PR, Fults K, Hickey AJ.

Pharm Res. 1990 Dec;7(12):1228-33.

PMID:
2095559

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