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The airway microbiota in children newly diagnosed with bronchiectasis largely retains its diversity.

Pillarisetti N, Broderick D, Ainsworth A, Mulholland A, Wagner Mackenzie B, Middleton D, Byrnes CA, Taylor MW.

Eur Respir J. 2019 Apr 25. pii: 1900704. doi: 10.1183/13993003.00704-2019. [Epub ahead of print] No abstract available.


HOspitalised Pneumonia Extended (HOPE) Study to reduce the long-term effects of childhood pneumonia: protocol for a multicentre, double-blind, parallel, superiority randomised controlled trial.

Chang AB, Fong SM, Yeo TW, Ware RS, McCallum GB, Nathan AM, Ooi MH, de Bruyne J, Byrnes CA, Lee B, Nachiappan N, Saari N, Torzillo P, Smith-Vaughan H, Morris PS, Upham JW, Grimwood K.

BMJ Open. 2019 Apr 24;9(4):e026411. doi: 10.1136/bmjopen-2018-026411.


Direct identification of microribonucleic acid miR-451 from plasma using liquid chromatography mass spectrometry.

Basiri B, Sutton JM, Hooshfar S, Byrnes CC, Murph MM, Bartlett MG.

J Chromatogr A. 2019 Jan 11;1584:97-105. doi: 10.1016/j.chroma.2018.11.029. Epub 2018 Nov 16.


miR-122-5p Expression and Secretion in Melanoma Cells Is Amplified by the LPAR3 SH3-Binding Domain to Regulate Wnt1.

Byrnes CC, Jia W, Alshamrani AA, Kuppa SS, Murph MM.

Mol Cancer Res. 2019 Jan;17(1):299-309. doi: 10.1158/1541-7786.MCR-18-0460. Epub 2018 Sep 28.


Amoxicillin-clavulanate versus azithromycin for respiratory exacerbations in children with bronchiectasis (BEST-2): a multicentre, double-blind, non-inferiority, randomised controlled trial.

Goyal V, Grimwood K, Byrnes CA, Morris PS, Masters IB, Ware RS, McCallum GB, Binks MJ, Marchant JM, van Asperen P, O'Grady KF, Champion A, Buntain HM, Petsky H, Torzillo PJ, Chang AB.

Lancet. 2018 Oct 6;392(10154):1197-1206. doi: 10.1016/S0140-6736(18)31723-9. Epub 2018 Sep 18.


Bronchiectasis: Treatment decisions for pulmonary exacerbations and their prevention.

Bell SC, Elborn JS, Byrnes CA.

Respirology. 2018 Nov;23(11):1006-1022. doi: 10.1111/resp.13398. Epub 2018 Sep 11. Review.


Surface-promoted hydrolysis of 2,4,6-trinitrotoluene and 2,4-dinitroanisole on pyrogenic carbonaceous matter.

Ding K, Byrnes C, Bridge J, Grannas A, Xu W.

Chemosphere. 2018 Apr;197:603-610. doi: 10.1016/j.chemosphere.2018.01.038.


Validity Evidence for a Serious Game to Assess Performance on Critical Pediatric Emergency Medicine Scenarios.

Gerard JM, Scalzo AJ, Borgman MA, Watson CM, Byrnes CE, Chang TP, Auerbach M, Kessler DO, Feldman BL, Payne BS, Nibras S, Chokshi RK, Lopreiato JO.

Simul Healthc. 2018 Jun;13(3):168-180. doi: 10.1097/SIH.0000000000000283.


Tough decoy targeting of predominant let-7 miRNA species in adult human hematopoietic cells.

de Vasconcellos JF, Byrnes C, Lee YT, Allwardt JM, Kaushal M, Rabel A, Miller JL.

J Transl Med. 2017 Aug 2;15(1):169. doi: 10.1186/s12967-017-1273-x.


IGF2BP1 overexpression causes fetal-like hemoglobin expression patterns in cultured human adult erythroblasts.

de Vasconcellos JF, Tumburu L, Byrnes C, Lee YT, Xu PC, Li M, Rabel A, Clarke BA, Guydosh NR, Proia RL, Miller JL.

Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):E5664-E5672. doi: 10.1073/pnas.1609552114. Epub 2017 Jun 26.


Pediatric Trainees Managing a Difficult Airway: Comparison of Laryngeal Mask Airway, Direct, and Video-Assisted Laryngoscopy.

Ambrosio A, Marvin K, Perez C, Byrnes C, Gaconnet C, Cornelissen C, Brigger M.

OTO Open. 2017 May 8;1(2):2473974X17707916. doi: 10.1177/2473974X17707916. eCollection 2017 Apr-Jun.


Accrual of Bone Mass in Children and Adolescents With Cystic Fibrosis.

Sharma S, Jaksic M, Fenwick S, Byrnes C, Cundy T.

J Clin Endocrinol Metab. 2017 May 1;102(5):1734-1739. doi: 10.1210/jc.2016-3459.


HMGA2 Moderately Increases Fetal Hemoglobin Expression in Human Adult Erythroblasts.

de Vasconcellos JF, Lee YT, Byrnes C, Tumburu L, Rabel A, Miller JL.

PLoS One. 2016 Nov 18;11(11):e0166928. doi: 10.1371/journal.pone.0166928. eCollection 2016.


Examination of Reticulocytosis among Chronically Transfused Children with Sickle Cell Anemia.

Kaushal M, Byrnes C, Khademian Z, Duncan N, Luban NL, Miller JL, Fasano RM, Meier ER.

PLoS One. 2016 Apr 26;11(4):e0153244. doi: 10.1371/journal.pone.0153244. eCollection 2016.


Erythroid-Specific Expression of LIN28A Is Sufficient for Robust Gamma-Globin Gene and Protein Expression in Adult Erythroblasts.

Lee YT, de Vasconcellos JF, Byrnes C, Kaushal M, Rabel A, Tumburu L, Allwardt JM, Miller JL.

PLoS One. 2015 Dec 16;10(12):e0144977. doi: 10.1371/journal.pone.0144977. eCollection 2015.


Absolute Reticulocyte Count Acts as a Surrogate for Fetal Hemoglobin in Infants and Children with Sickle Cell Anemia.

Meier ER, Byrnes C, Weissman M, Lee YT, Miller JL.

PLoS One. 2015 Sep 14;10(9):e0136672. doi: 10.1371/journal.pone.0136672. eCollection 2015.


Nasopharyngeal carriage and macrolide resistance in Indigenous children with bronchiectasis randomized to long-term azithromycin or placebo.

Hare KM, Grimwood K, Chang AB, Chatfield MD, Valery PC, Leach AJ, Smith-Vaughan HC, Morris PS, Byrnes CA, Torzillo PJ, Cheng AC.

Eur J Clin Microbiol Infect Dis. 2015 Nov;34(11):2275-85. doi: 10.1007/s10096-015-2480-0. Epub 2015 Sep 12.


Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping.

Krivega I, Byrnes C, de Vasconcellos JF, Lee YT, Kaushal M, Dean A, Miller JL.

Blood. 2015 Jul 30;126(5):665-72. doi: 10.1182/blood-2015-02-629972. Epub 2015 May 15.


Three-weekly doses of azithromycin for indigenous infants hospitalized with bronchiolitis: a multicentre, randomized, placebo-controlled trial.

McCallum GB, Morris PS, Grimwood K, Maclennan C, White AV, Chatfield MD, Sloots TP, Mackay IM, Smith-Vaughan H, McKay CC, Versteegh LA, Jacobsen N, Mobberley C, Byrnes CA, Chang AB.

Front Pediatr. 2015 Apr 21;3:32. doi: 10.3389/fped.2015.00032. eCollection 2015.


Toward making inroads in reducing the disparity of lung health in Australian indigenous and new zealand māori children.

Chang AB, Marsh RL, Upham JW, Hoffman LR, Smith-Vaughan H, Holt D, Toombs M, Byrnes C, Yerkovich ST, Torzillo PJ, O'Grady KA, Grimwood K.

Front Pediatr. 2015 Feb 13;3:9. doi: 10.3389/fped.2015.00009. eCollection 2015. Review. No abstract available.


Chronic suppurative lung disease and bronchiectasis in children and adults in Australia and New Zealand Thoracic Society of Australia and New Zealand guidelines.

Chang AB, Bell SC, Torzillo PJ, King PT, Maguire GP, Byrnes CA, Holland AE, O'Mara P, Grimwood K; extended voting group.

Med J Aust. 2015 Feb 16;202(3):130. No abstract available.


Chronic suppurative lung disease and bronchiectasis in children and adults in Australia and New Zealand Thoracic Society of Australia and New Zealand guidelines.

Chang AB, Bell SC, Torzillo PJ, King PT, Maguire GP, Byrnes CA, Holland AE, O'Mara P, Grimwood K; extended voting group.

Med J Aust. 2015 Jan 19;202(1):21-3. No abstract available. Erratum in: Med J Aust. 2015 Feb 16;202(3):130.


Mechanisms of plasma non-transferrin bound iron generation: insights from comparing transfused diamond blackfan anaemia with sickle cell and thalassaemia patients.

Porter JB, Walter PB, Neumayr LD, Evans P, Bansal S, Garbowski M, Weyhmiller MG, Harmatz PR, Wood JC, Miller JL, Byrnes C, Weiss G, Seifert M, Grosse R, Grabowski D, Schmidt A, Fischer R, Nielsen P, Niemeyer C, Vichinsky E.

Br J Haematol. 2014 Dec;167(5):692-6. doi: 10.1111/bjh.13081. Epub 2014 Sep 11.


LIN28A expression reduces sickling of cultured human erythrocytes.

de Vasconcellos JF, Fasano RM, Lee YT, Kaushal M, Byrnes C, Meier ER, Anderson M, Rabel A, Braylan R, Stroncek DF, Miller JL.

PLoS One. 2014 Sep 4;9(9):e106924. doi: 10.1371/journal.pone.0106924. eCollection 2014.


Costs of bronchoalveolar lavage-directed therapy in the first 5 years of life for children with cystic fibrosis.

Moodie M, Lal A, Vidmar S, Armstrong DS, Byrnes CA, Carlin JB, Cheney J, Cooper PJ, Grimwood K, Robertson CF, Tiddens HA, Wainwright CE; Australasian Cystic Fibrosis Bronchoalveolar Lavage Study Investigators.

J Pediatr. 2014 Sep;165(3):564-569.e5. doi: 10.1016/j.jpeds.2014.05.031. Epub 2014 Jul 1.


Long-term azithromycin for Indigenous children with non-cystic-fibrosis bronchiectasis or chronic suppurative lung disease (Bronchiectasis Intervention Study): a multicentre, double-blind, randomised controlled trial.

Valery PC, Morris PS, Byrnes CA, Grimwood K, Torzillo PJ, Bauert PA, Masters IB, Diaz A, McCallum GB, Mobberley C, Tjhung I, Hare KM, Ware RS, Chang AB.

Lancet Respir Med. 2013 Oct;1(8):610-620. doi: 10.1016/S2213-2600(13)70185-1. Epub 2013 Sep 17. Erratum in: Lancet Respir Med. 2015 Aug;3(8):e29.


Increased reticulocytosis during infancy is associated with increased hospitalizations in sickle cell anemia patients during the first three years of life.

Meier ER, Byrnes C, Lee YT, Wright EC, Schechter AN, Luban NL, Miller JL.

PLoS One. 2013 Aug 7;8(8):e70794. doi: 10.1371/journal.pone.0070794. eCollection 2013.


A synthetic model of human beta-thalassemia erythropoiesis using CD34+ cells from healthy adult donors.

Lee YT, Kim KS, Byrnes C, de Vasconcellos JF, Noh SJ, Rabel A, Meier ER, Miller JL.

PLoS One. 2013 Jul 8;8(7):e68307. doi: 10.1371/journal.pone.0068307. Print 2013.


LIN28B-mediated expression of fetal hemoglobin and production of fetal-like erythrocytes from adult human erythroblasts ex vivo.

Lee YT, de Vasconcellos JF, Yuan J, Byrnes C, Noh SJ, Meier ER, Kim KS, Rabel A, Kaushal M, Muljo SA, Miller JL.

Blood. 2013 Aug 8;122(6):1034-41. doi: 10.1182/blood-2012-12-472308. Epub 2013 Jun 24.


Heated humidification improves clinical outcomes, compared to a heat and moisture exchanger in children with tracheostomies.

McNamara DG, Asher MI, Rubin BK, Stewart A, Byrnes CA.

Respir Care. 2014 Jan;59(1):46-53. doi: 10.4187/respcare.02214. Epub 2013 Jun 13.


Iron dose-dependent differentiation and enucleation of human erythroblasts in serum-free medium.

Byrnes C, Lee YT, Meier ER, Rabel A, Sacks DB, Miller JL.

J Tissue Eng Regen Med. 2016 Feb;10(2):E84-9. doi: 10.1002/term.1743. Epub 2013 Apr 18.


Bronchiectasis exacerbation study on azithromycin and amoxycillin-clavulanate for respiratory exacerbations in children (BEST-2): study protocol for a randomized controlled trial.

Chang AB, Grimwood K, Wilson AC, van Asperen PP, Byrnes CA, O'Grady KA, Sloots TP, Robertson CF, Torzillo PJ, McCallum GB, Masters IB, Buntain HM, Mackay IM, Ungerer J, Tuppin J, Morris PS.

Trials. 2013 Feb 20;14:53. doi: 10.1186/1745-6215-14-53.


Indigenous children from three countries with non-cystic fibrosis chronic suppurative lung disease/bronchiectasis.

Singleton RJ, Valery PC, Morris P, Byrnes CA, Grimwood K, Redding G, Torzillo PJ, McCallum G, Chikoyak L, Mobberly C, Holman RC, Chang AB.

Pediatr Pulmonol. 2014 Feb;49(2):189-200. doi: 10.1002/ppul.22763. Epub 2013 Feb 8.


Prospective evaluation of respiratory exacerbations in children with cystic fibrosis from newborn screening to 5 years of age.

Byrnes CA, Vidmar S, Cheney JL, Carlin JB, Armstrong DS, Cooper PJ, Grimwood K, Moodie M, Robertson CF, Rosenfeld M, Tiddens HA, Wainwright CE; ACFBAL Study Investigators.

Thorax. 2013 Jul;68(7):643-51. doi: 10.1136/thoraxjnl-2012-202342. Epub 2013 Jan 23.


Respiratory health outcomes 1 year after admission with severe lower respiratory tract infection.

Trenholme AA, Byrnes CA, McBride C, Lennon DR, Chan-Mow F, Vogel AM, Stewart JM, Percival T.

Pediatr Pulmonol. 2013 Aug;48(8):772-9. doi: 10.1002/ppul.22661. Epub 2012 Sep 19.


Antibiotics for bronchiectasis exacerbations in children: rationale and study protocol for a randomised placebo-controlled trial.

Chang AB, Grimwood K, Robertson CF, Wilson AC, van Asperen PP, O'Grady KA, Sloots TP, Torzillo PJ, Bailey EJ, McCallum GB, Masters IB, Byrnes CA, Chatfield MD, Buntain HM, Mackay IM, Morris PS.

Trials. 2012 Aug 31;13:156. doi: 10.1186/1745-6215-13-156.


Azithromycin for Indigenous children with bronchiectasis: study protocol for a multi-centre randomized controlled trial.

Valery PC, Morris PS, Grimwood K, Torzillo PJ, Byrnes CA, Masters IB, Bauert PA, McCallum GB, Mobberly C, Chang AB.

BMC Pediatr. 2012 Aug 14;12:122.


An acute groin lump: surgical exploration is not always the best option.

Davey PT, Byrnes C.

Ann R Coll Surg Engl. 2012 Jan;94(1):e13-4. doi: 10.1308/003588412X13171221499063.


Calpastatin controls polymicrobial sepsis by limiting procoagulant microparticle release.

Zafrani L, Gerotziafas G, Byrnes C, Hu X, Perez J, Lévi C, Placier S, Letavernier E, Leelahavanichkul A, Haymann JP, Elalamy I, Miller JL, Star RA, Yuen PS, Baud L.

Am J Respir Crit Care Med. 2012 Apr 1;185(7):744-55. doi: 10.1164/rccm.201109-1686OC. Epub 2012 Jan 20.


Identification of a cross-reacting, monoclonal anti-human CD233 antibody for identification and sorting of rhesus macaque erythrocytes.

Byrnes C, Terry Lee Y, Donahue RE, Miller JL.

Cytometry A. 2012 Feb;81(2):165-8. doi: 10.1002/cyto.a.22005. Epub 2011 Dec 13.


Effect of bronchoalveolar lavage-directed therapy on Pseudomonas aeruginosa infection and structural lung injury in children with cystic fibrosis: a randomized trial.

Wainwright CE, Vidmar S, Armstrong DS, Byrnes CA, Carlin JB, Cheney J, Cooper PJ, Grimwood K, Moodie M, Robertson CF, Tiddens HA; ACFBAL Study Investigators.

JAMA. 2011 Jul 13;306(2):163-71. doi: 10.1001/jama.2011.954.


Diagnosing and preventing chronic suppurative lung disease (CSLD) and bronchiectasis.

Chang AB, Byrnes CA, Everard ML.

Paediatr Respir Rev. 2011 Jun;12(2):97-103. doi: 10.1016/j.prrv.2010.10.008. Epub 2010 Dec 4.


Expression patterns of fetal hemoglobin in sickle cell erythrocytes are both patient- and treatment-specific during childhood.

Meier ER, Byrnes C, Weissman M, Noel P, Luban NL, Miller JL.

Pediatr Blood Cancer. 2011 Jan;56(1):103-9. doi: 10.1002/pbc.22643.


Respiratory infections in Tamariki (children) and Taitamariki (young people) Māori, New Zealand.

Byrnes CA, Trenholme A.

J Paediatr Child Health. 2010 Sep;46(9):521-6. doi: 10.1111/j.1440-1754.2010.01853.x. Review.


Chronic suppurative lung disease and bronchiectasis in children and adults in Australia and New Zealand.

Chang AB, Bell SC, Byrnes CA, Grimwood K, Holmes PW, King PT, Kolbe J, Landau LI, Maguire GP, McDonald MI, Reid DW, Thien FC, Torzillo PJ.

Med J Aust. 2010 Sep 20;193(6):356-65.


Do New Zealand children with non-cystic fibrosis bronchiectasis show disease progression?

Munro KA, Reed PW, Joyce H, Perry D, Twiss J, Byrnes CA, Edwards EA.

Pediatr Pulmonol. 2011 Feb;46(2):131-8. doi: 10.1002/ppul.21331. Epub 2010 Aug 17.


A prospective randomized trial comparing supraglottic airways for flexible bronchoscopy in children.

Baker PA, Brunette KE, Byrnes CA, Thompson JM.

Paediatr Anaesth. 2010 Sep;20(9):831-8. doi: 10.1111/j.1460-9592.2010.03362.x.


A transcriptome-based examination of blood group expression.

Noh SJ, Lee YT, Byrnes C, Miller JL.

Transfus Clin Biol. 2010 Sep;17(3):120-5. doi: 10.1016/j.tracli.2010.06.010. Epub 2010 Aug 3.


Chronic respiratory symptoms and diseases among indigenous children.

Redding GJ, Byrnes CA.

Pediatr Clin North Am. 2009 Dec;56(6):1323-42. doi: 10.1016/j.pcl.2009.09.012. Review.


The perceptions and preferences of parents of children with tracheostomies in a study of humidification therapy.

McNamara DG, Dickinson AR, Byrnes CA.

J Child Health Care. 2009 Sep;13(3):179-97. doi: 10.1177/1367493509336686.


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