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Items: 23


Tumor cell-intrinsic EPHA2 suppresses anti-tumor immunity by regulating PTGS2 (COX-2).

Markosyan N, Li J, Sun YH, Richman LP, Lin JH, Yan F, Quinones L, Sela Y, Yamazoe T, Gordon N, Tobias JW, Byrne KT, Rech AJ, FitzGerald GA, Stanger BZ, Vonderheide RH.

J Clin Invest. 2019 Jun 4;130:3594-3609. doi: 10.1172/JCI127755.


Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy.

Li J, Byrne KT, Yan F, Yamazoe T, Chen Z, Baslan T, Richman LP, Lin JH, Sun YH, Rech AJ, Balli D, Hay CA, Sela Y, Merrell AJ, Liudahl SM, Gordon N, Norgard RJ, Yuan S, Yu S, Chao T, Ye S, Eisinger-Mathason TSK, Faryabi RB, Tobias JW, Lowe SW, Coussens LM, Wherry EJ, Vonderheide RH, Stanger BZ.

Immunity. 2018 Jul 17;49(1):178-193.e7. doi: 10.1016/j.immuni.2018.06.006. Epub 2018 Jun 26.


Immunotherapy and Prevention of Pancreatic Cancer.

Morrison AH, Byrne KT, Vonderheide RH.

Trends Cancer. 2018 Jun;4(6):418-428. doi: 10.1016/j.trecan.2018.04.001. Epub 2018 Apr 30. Review.


Resident memory T cells in the skin mediate durable immunity to melanoma.

Malik BT, Byrne KT, Vella JL, Zhang P, Shabaneh TB, Steinberg SM, Molodtsov AK, Bowers JS, Angeles CV, Paulos CM, Huang YH, Turk MJ.

Sci Immunol. 2017 Apr 14;2(10). pii: eaam6346. doi: 10.1126/sciimmunol.aam6346.


Lack of immunoediting in murine pancreatic cancer reversed with neoantigen.

Evans RA, Diamond MS, Rech AJ, Chao T, Richardson MW, Lin JH, Bajor DL, Byrne KT, Stanger BZ, Riley JL, Markosyan N, Winograd R, Vonderheide RH.

JCI Insight. 2016 Sep 8;1(14). pii: 88328. doi: 10.1172/jci.insight.88328.


CD40 Stimulation Obviates Innate Sensors and Drives T Cell Immunity in Cancer.

Byrne KT, Vonderheide RH.

Cell Rep. 2016 Jun 21;15(12):2719-32. doi: 10.1016/j.celrep.2016.05.058. Epub 2016 Jun 9.


CSF-1R-Dependent Lethal Hepatotoxicity When Agonistic CD40 Antibody Is Given before but Not after Chemotherapy.

Byrne KT, Leisenring NH, Bajor DL, Vonderheide RH.

J Immunol. 2016 Jul 1;197(1):179-87. doi: 10.4049/jimmunol.1600146. Epub 2016 May 23.


Trends in bariatric surgery, 2002-2012: do changes parallel the obesity trend?

Johnson EE, Simpson AN, Harvey JB, Lockett MA, Byrne KT, Simpson KN.

Surg Obes Relat Dis. 2016 Feb;12(2):398-404. doi: 10.1016/j.soard.2015.07.009. Epub 2015 Jul 17.


Special Conference on Tumor Immunology and Immunotherapy: A New Chapter.

Byrne KT, Vonderheide RH, Jaffee EM, Armstrong TD.

Cancer Immunol Res. 2015 Jun;3(6):590-597. doi: 10.1158/2326-6066.CIR-15-0106. Epub 2015 May 12.


Induction of T-cell Immunity Overcomes Complete Resistance to PD-1 and CTLA-4 Blockade and Improves Survival in Pancreatic Carcinoma.

Winograd R, Byrne KT, Evans RA, Odorizzi PM, Meyer AR, Bajor DL, Clendenin C, Stanger BZ, Furth EE, Wherry EJ, Vonderheide RH.

Cancer Immunol Res. 2015 Apr;3(4):399-411. doi: 10.1158/2326-6066.CIR-14-0215. Epub 2015 Feb 12.


BRAF inhibition alleviates immune suppression in murine autochthonous melanoma.

Steinberg SM, Zhang P, Malik BT, Boni A, Shabaneh TB, Byrne KT, Mullins DW, Brinckerhoff CE, Ernstoff MS, Bosenberg MW, Turk MJ.

Cancer Immunol Res. 2014 Nov;2(11):1044-50. doi: 10.1158/2326-6066.CIR-14-0074. Epub 2014 Sep 2.


A closer look at the nature of anxiety in weight loss surgery candidates.

Edwards-Hampton SA, Madan A, Wedin S, Borckardt JJ, Crowley N, Byrne KT.

Int J Psychiatry Med. 2014;47(2):105-13. doi: 10.2190/PM.47.2.b.


Autoimmune vitiligo does not require the ongoing priming of naive CD8 T cells for disease progression or associated protection against melanoma.

Byrne KT, Zhang P, Steinberg SM, Turk MJ.

J Immunol. 2014 Feb 15;192(4):1433-9. doi: 10.4049/jimmunol.1302139. Epub 2014 Jan 8.


CD40 therapy and surgery: a potential immunologic partnership.

Byrne KT, Vonderheide RH.

J Immunother. 2013 Sep;36(7):359-61. doi: 10.1097/CJI.0b013e31829fb871. No abstract available.


Immune-mediated regression of established B16F10 melanoma by intratumoral injection of attenuated Toxoplasma gondii protects against rechallenge.

Baird JR, Byrne KT, Lizotte PH, Toraya-Brown S, Scarlett UK, Alexander MP, Sheen MR, Fox BA, Bzik DJ, Bosenberg M, Mullins DW, Turk MJ, Fiering S.

J Immunol. 2013 Jan 1;190(1):469-78. doi: 10.4049/jimmunol.1201209. Epub 2012 Dec 7.


Protective CD8 memory T cell responses to mouse melanoma are generated in the absence of CD4 T cell help.

Côté AL, Byrne KT, Steinberg SM, Zhang P, Turk MJ.

PLoS One. 2011;6(10):e26491. doi: 10.1371/journal.pone.0026491. Epub 2011 Oct 26.


New perspectives on the role of vitiligo in immune responses to melanoma.

Byrne KT, Turk MJ.

Oncotarget. 2011 Sep;2(9):684-94. Review.


Autoimmune melanocyte destruction is required for robust CD8+ memory T cell responses to mouse melanoma.

Byrne KT, Côté AL, Zhang P, Steinberg SM, Guo Y, Allie R, Zhang W, Ernstoff MS, Usherwood EJ, Turk MJ.

J Clin Invest. 2011 May;121(5):1797-809. doi: 10.1172/JCI44849. Epub 2011 Apr 11.


IL-10 immunomodulation of myeloid cells regulates a murine model of ovarian cancer.

Hart KM, Byrne KT, Molloy MJ, Usherwood EM, Berwin B.

Front Immunol. 2011 Jul 21;2:29. doi: 10.3389/fimmu.2011.00029. eCollection 2011.


Targeting transcription factor Stat4 uncovers a role for interleukin-18 in the pathogenesis of severe lupus nephritis in mice.

Menke J, Bork T, Kutska B, Byrne KT, Blanfeld M, Relle M, Kelley VR, Schwarting A.

Kidney Int. 2011 Feb;79(4):452-63. doi: 10.1038/ki.2010.438. Epub 2010 Oct 27.


Circulating CSF-1 promotes monocyte and macrophage phenotypes that enhance lupus nephritis.

Menke J, Rabacal WA, Byrne KT, Iwata Y, Schwartz MM, Stanley ER, Schwarting A, Kelley VR.

J Am Soc Nephrol. 2009 Dec;20(12):2581-92. doi: 10.1681/ASN.2009050499. Epub 2009 Nov 19.


Sunlight triggers cutaneous lupus through a CSF-1-dependent mechanism in MRL-Fas(lpr) mice.

Menke J, Hsu MY, Byrne KT, Lucas JA, Rabacal WA, Croker BP, Zong XH, Stanley ER, Kelley VR.

J Immunol. 2008 Nov 15;181(10):7367-79.


Significant analgesic effects of one session of postoperative left prefrontal cortex repetitive transcranial magnetic stimulation: a replication study.

Borckardt JJ, Reeves ST, Weinstein M, Smith AR, Shelley N, Kozel FA, Nahas Z, Byrne KT, Morgan K, George MS.

Brain Stimul. 2008 Apr;1(2):122-7. doi: 10.1016/j.brs.2008.04.002.

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