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Items: 10


Overexpression of IL-11 promotes premalignant gastric epithelial hyperplasia in isolation from germline gp130-JAK-STAT driver mutations.

Buzzelli JN, O'Connor L, Scurr M, Chung Nien Chin S, Catubig A, Ng GZ, Oshima M, Oshima H, Giraud AS, Sutton P, Judd LM, Menheniott TR.

Am J Physiol Gastrointest Liver Physiol. 2019 Feb 1;316(2):G251-G262. doi: 10.1152/ajpgi.00304.2018. Epub 2018 Dec 6.


Radiation combined with macrophage depletion promotes adaptive immunity and potentiates checkpoint blockade.

Jones KI, Tiersma J, Yuzhalin AE, Gordon-Weeks AN, Buzzelli J, Im JH, Muschel RJ.

EMBO Mol Med. 2018 Dec;10(12). pii: e9342. doi: 10.15252/emmm.201809342.


Itraconazole targets cell cycle heterogeneity in colorectal cancer.

Buczacki SJA, Popova S, Biggs E, Koukorava C, Buzzelli J, Vermeulen L, Hazelwood L, Francies H, Garnett MJ, Winton DJ.

J Exp Med. 2018 Jul 2;215(7):1891-1912. doi: 10.1084/jem.20171385. Epub 2018 May 31.


Colorectal cancer liver metastases organoids retain characteristics of original tumor and acquire chemotherapy resistance.

Buzzelli JN, Ouaret D, Brown G, Allen PD, Muschel RJ.

Stem Cell Res. 2018 Mar;27:109-120. doi: 10.1016/j.scr.2018.01.016. Epub 2018 Jan 28.


Neutrophils promote hepatic metastasis growth through fibroblast growth factor 2-dependent angiogenesis in mice.

Gordon-Weeks AN, Lim SY, Yuzhalin AE, Jones K, Markelc B, Kim KJ, Buzzelli JN, Fokas E, Cao Y, Smart S, Muschel R.

Hepatology. 2017 Jun;65(6):1920-1935. doi: 10.1002/hep.29088. Epub 2017 May 2.


Elevated IL-33 expression is associated with pediatric eosinophilic esophagitis, and exogenous IL-33 promotes eosinophilic esophagitis development in mice.

Judd LM, Heine RG, Menheniott TR, Buzzelli J, O'Brien-Simpson N, Pavlic D, O'Connor L, Al Gazali K, Hamilton O, Scurr M, Collison AM, Mattes J, Allen KJ, Giraud AS.

Am J Physiol Gastrointest Liver Physiol. 2016 Jan 1;310(1):G13-25. doi: 10.1152/ajpgi.00290.2015. Epub 2015 Oct 29.


IL33 Is a Stomach Alarmin That Initiates a Skewed Th2 Response to Injury and Infection.

Buzzelli JN, Chalinor HV, Pavlic DI, Sutton P, Menheniott TR, Giraud AS, Judd LM.

Cell Mol Gastroenterol Hepatol. 2015 Jan 3;1(2):203-221.e3. doi: 10.1016/j.jcmgh.2014.12.003. eCollection 2015 Mar.


IL-1RT1 signaling antagonizes IL-11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment.

Buzzelli JN, Pavlic DI, Chalinor HV, O'Connor L, Menheniott TR, Giraud AS, Judd LM.

Oncotarget. 2015 Jan 20;6(2):679-95.


IL-11 is a parietal cell cytokine that induces atrophic gastritis.

Howlett M, Chalinor HV, Buzzelli JN, Nguyen N, van Driel IR, Bell KM, Fox JG, Dimitriadis E, Menheniott TR, Giraud AS, Judd LM.

Gut. 2012 Oct;61(10):1398-409. doi: 10.1136/gutjnl-2011-300539. Epub 2011 Dec 16.


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