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Items: 23


Safe and Sustained Expression of Human Iduronidase After Intrathecal Administration of Adeno-Associated Virus Serotype 9 in Infant Rhesus Monkeys.

Hordeaux J, Hinderer C, Buza EL, Louboutin JP, Jahan T, Bell P, Chichester JA, Tarantal AF, Wilson JM.

Hum Gene Ther. 2019 Aug;30(8):957-966. doi: 10.1089/hum.2019.012. Epub 2019 Jun 10.


A Gene Therapy Approach to Improve Copper Metabolism and Prevent Liver Damage in a Mouse Model of Wilson Disease.

Greig JA, Nordin JML, Smith MK, Ashley SN, Draper C, Zhu Y, Bell P, Buza EL, Wilson JM.

Hum Gene Ther Clin Dev. 2019 Mar;30(1):29-39. doi: 10.1089/humc.2018.219. Epub 2019 Feb 25.


Adeno-associated viral gene therapy corrects a mouse model of argininosuccinic aciduria.

Ashley SN, Nordin JML, Buza EL, Greig JA, Wilson JM.

Mol Genet Metab. 2018 Nov;125(3):241-250. doi: 10.1016/j.ymgme.2018.08.013. Epub 2018 Aug 28.


Toxicology Study of Intra-Cisterna Magna Adeno-Associated Virus 9 Expressing Human Alpha-L-Iduronidase in Rhesus Macaques.

Hordeaux J, Hinderer C, Goode T, Katz N, Buza EL, Bell P, Calcedo R, Richman LK, Wilson JM.

Mol Ther Methods Clin Dev. 2018 Jul 14;10:79-88. doi: 10.1016/j.omtm.2018.06.003. eCollection 2018 Sep 21.


Toxicology Study of Intra-Cisterna Magna Adeno-Associated Virus 9 Expressing Iduronate-2-Sulfatase in Rhesus Macaques.

Hordeaux J, Hinderer C, Goode T, Buza EL, Bell P, Calcedo R, Richman LK, Wilson JM.

Mol Ther Methods Clin Dev. 2018 Jul 14;10:68-78. doi: 10.1016/j.omtm.2018.06.004. eCollection 2018 Sep 21.


Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol.

Wang L, Smith J, Breton C, Clark P, Zhang J, Ying L, Che Y, Lape J, Bell P, Calcedo R, Buza EL, Saveliev A, Bartsevich VV, He Z, White J, Li M, Jantz D, Wilson JM.

Nat Biotechnol. 2018 Sep;36(8):717-725. doi: 10.1038/nbt.4182. Epub 2018 Jul 9.


The Neurotropic Properties of AAV-PHP.B Are Limited to C57BL/6J Mice.

Hordeaux J, Wang Q, Katz N, Buza EL, Bell P, Wilson JM.

Mol Ther. 2018 Mar 7;26(3):664-668. doi: 10.1016/j.ymthe.2018.01.018. Epub 2018 Feb 2.


Severe Toxicity in Nonhuman Primates and Piglets Following High-Dose Intravenous Administration of an Adeno-Associated Virus Vector Expressing Human SMN.

Hinderer C, Katz N, Buza EL, Dyer C, Goode T, Bell P, Richman LK, Wilson JM.

Hum Gene Ther. 2018 Mar;29(3):285-298. doi: 10.1089/hum.2018.015. Epub 2018 Feb 12.


Mucopolysaccharidosis Type VI in a Great Dane Caused by a Nonsense Mutation in the ARSB Gene.

Wang P, Margolis C, Lin G, Buza EL, Quick S, Raj K, Han R, Giger U.

Vet Pathol. 2018 Mar;55(2):286-293. doi: 10.1177/0300985817732115. Epub 2017 Nov 20.


Fibroblast activation protein augments progression and metastasis of pancreatic ductal adenocarcinoma.

Lo A, Li CP, Buza EL, Blomberg R, Govindaraju P, Avery D, Monslow J, Hsiao M, Puré E.

JCI Insight. 2017 Oct 5;2(19). pii: 92232. doi: 10.1172/jci.insight.92232.


RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense.

Peterson LW, Philip NH, DeLaney A, Wynosky-Dolfi MA, Asklof K, Gray F, Choa R, Bjanes E, Buza EL, Hu B, Dillon CP, Green DR, Berger SB, Gough PJ, Bertin J, Brodsky IE.

J Exp Med. 2017 Nov 6;214(11):3171-3182. doi: 10.1084/jem.20170347. Epub 2017 Aug 30.


Context-Dependent Effects of Amplified MAPK Signaling during Lung Adenocarcinoma Initiation and Progression.

Cicchini M, Buza EL, Sagal KM, Gudiel AA, Durham AC, Feldser DM.

Cell Rep. 2017 Feb 21;18(8):1958-1969. doi: 10.1016/j.celrep.2017.01.069.


Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma.

Walter DM, Venancio OS, Buza EL, Tobias JW, Deshpande C, Gudiel AA, Kim-Kiselak C, Cicchini M, Yates TJ, Feldser DM.

Cancer Res. 2017 Apr 1;77(7):1719-1729. doi: 10.1158/0008-5472.CAN-16-2159. Epub 2017 Feb 15.


IL-27 Limits Type 2 Immunopathology Following Parainfluenza Virus Infection.

Muallem G, Wagage S, Sun Y, DeLong JH, Valenzuela A, Christian DA, Harms Pritchard G, Fang Q, Buza EL, Jain D, Elloso MM, López CB, Hunter CA.

PLoS Pathog. 2017 Jan 27;13(1):e1006173. doi: 10.1371/journal.ppat.1006173. eCollection 2017 Jan.


Genetic lineage tracing analysis of the cell of origin of hepatotoxin-induced liver tumors in mice.

Shin S, Wangensteen KJ, Teta-Bissett M, Wang YJ, Mosleh-Shirazi E, Buza EL, Greenbaum LE, Kaestner KH.

Hepatology. 2016 Oct;64(4):1163-1177. doi: 10.1002/hep.28602. Epub 2016 May 28.


Spontaneous Pancreatitis Caused by Tissue-Specific Gene Ablation of Hhex in Mice.

Ferreira MJ, McKenna LB, Zhang J, Reichert M, Bakir B, Buza EL, Furth EE, Bogue CW, Rustgi AK, Kaestner KH.

Cell Mol Gastroenterol Hepatol. 2015 Sep 1;1(5):550-569. doi: 10.1016/j.jcmgh.2015.06.007.


Hif1a Deletion Reveals Pro-Neoplastic Function of B Cells in Pancreatic Neoplasia.

Lee KE, Spata M, Bayne LJ, Buza EL, Durham AC, Allman D, Vonderheide RH, Simon MC.

Cancer Discov. 2016 Mar;6(3):256-69. doi: 10.1158/2159-8290.CD-15-0822. Epub 2015 Dec 29.


Engineering the gut microbiota to treat hyperammonemia.

Shen TC, Albenberg L, Bittinger K, Chehoud C, Chen YY, Judge CA, Chau L, Ni J, Sheng M, Lin A, Wilkins BJ, Buza EL, Lewis JD, Daikhin Y, Nissim I, Yudkoff M, Bushman FD, Wu GD.

J Clin Invest. 2015 Jul 1;125(7):2841-50. doi: 10.1172/JCI79214. Epub 2015 Jun 22.


The Group 3 Innate Lymphoid Cell Defect in Aryl Hydrocarbon Receptor Deficient Mice Is Associated with T Cell Hyperactivation during Intestinal Infection.

Wagage S, Harms Pritchard G, Dawson L, Buza EL, Sonnenberg GF, Hunter CA.

PLoS One. 2015 May 26;10(5):e0128335. doi: 10.1371/journal.pone.0128335. eCollection 2015.


Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells.

Lo A, Wang LS, Scholler J, Monslow J, Avery D, Newick K, O'Brien S, Evans RA, Bajor DJ, Clendenin C, Durham AC, Buza EL, Vonderheide RH, June CH, Albelda SM, Puré E.

Cancer Res. 2015 Jul 15;75(14):2800-2810. doi: 10.1158/0008-5472.CAN-14-3041. Epub 2015 May 15.


Malignant peripheral nerve sheath tumor in a cat with nodal and pulmonary metastases.

Buza EL, Menzies RA, Goldschmidt MH, Durham AC.

J Vet Diagn Invest. 2012 Jul;24(4):781-4. doi: 10.1177/1040638712445775. Epub 2012 May 17.


CT features of pleural masses and nodules.

Reetz JA, Buza EL, Krick EL.

Vet Radiol Ultrasound. 2012 Mar-Apr;53(2):121-7. doi: 10.1111/j.1740-8261.2011.01883.x.


Characterization of latent membrane protein 2 specificity in CTL lines from patients with EBV-positive nasopharyngeal carcinoma and lymphoma.

Straathof KC, Leen AM, Buza EL, Taylor G, Huls MH, Heslop HE, Rooney CM, Bollard CM.

J Immunol. 2005 Sep 15;175(6):4137-47. Erratum in: J Immunol. 2005 Nov 1;175(9):6238.

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