Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 561

1.

Targeting Mitochondria in Alzheimer Disease: Rationale and Perspectives.

Lanzillotta C, Di Domenico F, Perluigi M, Butterfield DA.

CNS Drugs. 2019 Aug 13. doi: 10.1007/s40263-019-00658-8. [Epub ahead of print]

PMID:
31410665
2.

Profiles of brain oxidative damage, ventricular alterations, and neurochemical metabolites in the striatum of PINK1 knockout rats as functions of age and gender: Relevance to Parkinson disease.

Ren X, Hinchie A, Swomley A, Powell DK, Butterfield DA.

Free Radic Biol Med. 2019 Aug 8;143:146-152. doi: 10.1016/j.freeradbiomed.2019.08.008. [Epub ahead of print]

PMID:
31401305
3.

Extracellular vesicle-mediated macrophage activation: An insight into the mechanism of thioredoxin-mediated immune activation.

Yarana C, Thompson H, Chaiswing L, Butterfield DA, Weiss H, Bondada S, Alhakeem S, Sukati S, St Clair DK.

Redox Biol. 2019 Sep;26:101237. doi: 10.1016/j.redox.2019.101237. Epub 2019 Jun 5.

4.

Phosphoproteomics of Alzheimer disease brain: Insights into altered brain protein regulation of critical neuronal functions and their contributions to subsequent cognitive loss.

Butterfield DA.

Biochim Biophys Acta Mol Basis Dis. 2019 Aug 1;1865(8):2031-2039. doi: 10.1016/j.bbadis.2018.08.035. Epub 2018 Aug 29. Review.

PMID:
31167728
5.

Active subseafloor microbial communities from Mariana back-arc venting fluids share metabolic strategies across different thermal niches and taxa.

Trembath-Reichert E, Butterfield DA, Huber JA.

ISME J. 2019 Sep;13(9):2264-2279. doi: 10.1038/s41396-019-0431-y. Epub 2019 May 9.

PMID:
31073213
6.

S100A4 alters metabolism and promotes invasion of lung cancer cells by up-regulating mitochondrial complex I protein NDUFS2.

Liu L, Qi L, Knifley T, Piecoro DW, Rychahou P, Liu J, Mitov MI, Martin J, Wang C, Wu J, Weiss HL, Butterfield DA, Evers BM, O'Connor KL, Chen M.

J Biol Chem. 2019 May 3;294(18):7516-7527. doi: 10.1074/jbc.RA118.004365. Epub 2019 Mar 18.

PMID:
30885944
7.

Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome.

Di Domenico F, Tramutola A, Barone E, Lanzillotta C, Defever O, Arena A, Zuliani I, Foppoli C, Iavarone F, Vincenzoni F, Castagnola M, Butterfield DA, Perluigi M.

Redox Biol. 2019 Mar 9:101162. doi: 10.1016/j.redox.2019.101162. [Epub ahead of print]

8.

Fluid geochemistry, local hydrology, and metabolic activity define methanogen community size and composition in deep-sea hydrothermal vents.

Stewart LC, Algar CK, Fortunato CS, Larson BI, Vallino JJ, Huber JA, Butterfield DA, Holden JF.

ISME J. 2019 Jul;13(7):1711-1721. doi: 10.1038/s41396-019-0382-3. Epub 2019 Mar 6.

PMID:
30842565
9.

Plausible biochemical mechanisms of chemotherapy-induced cognitive impairment ("chemobrain"), a condition that significantly impairs the quality of life of many cancer survivors.

Ren X, Boriero D, Chaiswing L, Bondada S, St Clair DK, Butterfield DA.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1088-1097. doi: 10.1016/j.bbadis.2019.02.007. Epub 2019 Feb 10. Review.

PMID:
30759363
10.

Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease.

Sharma N, Tramutola A, Lanzillotta C, Arena A, Blarzino C, Cassano T, Butterfield DA, Di Domenico F, Perluigi M, Barone E.

Neurobiol Dis. 2019 May;125:176-189. doi: 10.1016/j.nbd.2019.02.003. Epub 2019 Feb 6.

PMID:
30738142
11.

Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease.

Butterfield DA, Halliwell B.

Nat Rev Neurosci. 2019 Mar;20(3):148-160. doi: 10.1038/s41583-019-0132-6. Review.

PMID:
30737462
12.
13.

The triangle of death of neurons: Oxidative damage, mitochondrial dysfunction, and loss of choline-containing biomolecules in brains of mice treated with doxorubicin. Advanced insights into mechanisms of chemotherapy induced cognitive impairment ("chemobrain") involving TNF-α.

Ren X, Keeney JTR, Miriyala S, Noel T, Powell DK, Chaiswing L, Bondada S, St Clair DK, Butterfield DA.

Free Radic Biol Med. 2019 Apr;134:1-8. doi: 10.1016/j.freeradbiomed.2018.12.029. Epub 2018 Dec 26.

PMID:
30593843
14.

mTOR Inhibitor Everolimus in Regulatory T Cell Expansion for Clinical Application in Transplantation.

Gedaly R, De Stefano F, Turcios L, Hill M, Hidalgo G, Mitov MI, Alstott MC, Butterfield DA, Mitchell HC, Hart J, Al-Attar A, Jennings CD, Marti F.

Transplantation. 2019 Apr;103(4):705-715. doi: 10.1097/TP.0000000000002495.

PMID:
30451741
15.

Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome.

Tramutola A, Lanzillotta C, Barone E, Arena A, Zuliani I, Mosca L, Blarzino C, Butterfield DA, Perluigi M, Di Domenico F.

Transl Neurodegener. 2018 Nov 6;7:28. doi: 10.1186/s40035-018-0133-9. eCollection 2018.

16.

Protein nitration profile of CD3+ lymphocytes from Alzheimer disease patients: Novel hints on immunosenescence and biomarker detection.

Tramutola A, Abate G, Lanzillotta C, Triani F, Barone E, Iavarone F, Vincenzoni F, Castagnola M, Marziano M, Memo M, Garrafa E, Butterfield DA, Perluigi M, Di Domenico F, Uberti D.

Free Radic Biol Med. 2018 Dec;129:430-439. doi: 10.1016/j.freeradbiomed.2018.10.414. Epub 2018 Oct 12.

PMID:
30321702
17.

Redox proteomics and amyloid β-peptide: insights into Alzheimer disease.

Butterfield DA, Boyd-Kimball D.

J Neurochem. 2018 Sep 14. doi: 10.1111/jnc.14589. [Epub ahead of print] Review.

18.

Microdose Lithium NP03 Diminishes Pre-Plaque Oxidative Damage and Neuroinflammation in a Rat Model of Alzheimer's-like Amyloidosis.

Wilson EN, Do Carmo S, Iulita MF, Hall H, Austin GL, Jia DT, Malcolm JC, Foret MK, Marks AR, Butterfield DA, Cuello AC.

Curr Alzheimer Res. 2018;15(13):1220-1230. doi: 10.2174/1567205015666180904154446.

PMID:
30182855
19.

Doxorubicin-induced elevated oxidative stress and neurochemical alterations in brain and cognitive decline: protection by MESNA and insights into mechanisms of chemotherapy-induced cognitive impairment ("chemobrain").

Keeney JTR, Ren X, Warrier G, Noel T, Powell DK, Brelsfoard JM, Sultana R, Saatman KE, Clair DKS, Butterfield DA.

Oncotarget. 2018 Jul 13;9(54):30324-30339. doi: 10.18632/oncotarget.25718. eCollection 2018 Jul 13.

20.

Biliverdin Reductase-A Mediates the Beneficial Effects of Intranasal Insulin in Alzheimer Disease.

Barone E, Tramutola A, Triani F, Calcagnini S, Di Domenico F, Ripoli C, Gaetani S, Grassi C, Butterfield DA, Cassano T, Perluigi M.

Mol Neurobiol. 2019 Apr;56(4):2922-2943. doi: 10.1007/s12035-018-1231-5. Epub 2018 Aug 2.

PMID:
30073505
21.

Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease.

Tramutola A, Sharma N, Barone E, Lanzillotta C, Castellani A, Iavarone F, Vincenzoni F, Castagnola M, Butterfield DA, Gaetani S, Cassano T, Perluigi M, Di Domenico F.

Biochim Biophys Acta Mol Basis Dis. 2018 Oct;1864(10):3309-3321. doi: 10.1016/j.bbadis.2018.07.017. Epub 2018 Jul 18.

PMID:
30031227
22.

Poly-ubiquitin profile in Alzheimer disease brain.

Tramutola A, Triani F, Di Domenico F, Barone E, Cai J, Klein JB, Perluigi M, Butterfield DA.

Neurobiol Dis. 2018 Oct;118:129-141. doi: 10.1016/j.nbd.2018.07.006. Epub 2018 Jul 9.

PMID:
30003951
23.

Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: Implications for Alzheimer disease.

Triani F, Tramutola A, Di Domenico F, Sharma N, Butterfield DA, Head E, Perluigi M, Barone E.

Biochim Biophys Acta Mol Basis Dis. 2018 Oct;1864(10):3181-3194. doi: 10.1016/j.bbadis.2018.07.005. Epub 2018 Jul 5.

PMID:
29981845
24.

Oxidative Stress, Amyloid-β Peptide, and Altered Key Molecular Pathways in the Pathogenesis and Progression of Alzheimer's Disease.

Butterfield DA, Boyd-Kimball D.

J Alzheimers Dis. 2018;62(3):1345-1367. doi: 10.3233/JAD-170543. Review.

25.

Perspectives on Oxidative Stress in Alzheimer's Disease and Predictions of Future Research Emphases.

Butterfield DA.

J Alzheimers Dis. 2018;64(s1):S469-S479. doi: 10.3233/JAD-179912. Review.

PMID:
29504538
26.

Spatially distinct, temporally stable microbial populations mediate biogeochemical cycling at and below the seafloor in hydrothermal vent fluids.

Fortunato CS, Larson B, Butterfield DA, Huber JA.

Environ Microbiol. 2018 Feb;20(2):769-784. doi: 10.1111/1462-2920.14011. Epub 2017 Dec 15.

PMID:
29205750
27.

Down syndrome: From development to adult life to Alzheimer disease.

Butterfield DA, Perluigi M.

Free Radic Biol Med. 2018 Jan;114:1-2. doi: 10.1016/j.freeradbiomed.2017.10.374. Epub 2017 Oct 24. No abstract available.

PMID:
29079527
28.

Extracellular Vesicles Released by Cardiomyocytes in a Doxorubicin-Induced Cardiac Injury Mouse Model Contain Protein Biomarkers of Early Cardiac Injury.

Yarana C, Carroll D, Chen J, Chaiswing L, Zhao Y, Noel T, Alstott M, Bae Y, Dressler EV, Moscow JA, Butterfield DA, Zhu H, St Clair DK.

Clin Cancer Res. 2018 Apr 1;24(7):1644-1653. doi: 10.1158/1078-0432.CCR-17-2046. Epub 2017 Oct 25.

29.

Community Structure of Lithotrophically-Driven Hydrothermal Microbial Mats from the Mariana Arc and Back-Arc.

Hager KW, Fullerton H, Butterfield DA, Moyer CL.

Front Microbiol. 2017 Aug 28;8:1578. doi: 10.3389/fmicb.2017.01578. eCollection 2017.

30.

The role of charge in the toxicity of polymer-coated cerium oxide nanomaterials to Caenorhabditis elegans.

Arndt DA, Oostveen EK, Triplett J, Butterfield DA, Tsyusko OV, Collin B, Starnes DL, Cai J, Klein JB, Nass R, Unrine JM.

Comp Biochem Physiol C Toxicol Pharmacol. 2017 Oct;201:1-10. doi: 10.1016/j.cbpc.2017.08.009. Epub 2017 Sep 6.

PMID:
28888877
31.

mTOR in Down syndrome: Role in Aß and tau neuropathology and transition to Alzheimer disease-like dementia.

Di Domenico F, Tramutola A, Foppoli C, Head E, Perluigi M, Butterfield DA.

Free Radic Biol Med. 2018 Jan;114:94-101. doi: 10.1016/j.freeradbiomed.2017.08.009. Epub 2017 Aug 12. Review.

32.

Acute treatment with doxorubicin affects glutamate neurotransmission in the mouse frontal cortex and hippocampus.

Thomas TC, Beitchman JA, Pomerleau F, Noel T, Jungsuwadee P, Butterfield DA, Clair DKS, Vore M, Gerhardt GA.

Brain Res. 2017 Oct 1;1672:10-17. doi: 10.1016/j.brainres.2017.07.003. Epub 2017 Jul 11.

33.

Disturbance of redox homeostasis in Down Syndrome: Role of iron dysmetabolism.

Barone E, Arena A, Head E, Butterfield DA, Perluigi M.

Free Radic Biol Med. 2018 Jan;114:84-93. doi: 10.1016/j.freeradbiomed.2017.07.009. Epub 2017 Jul 10. Review.

34.

Evidence of the immunomodulatory role of dual PI3K/mTOR inhibitors in transplantation: an experimental study in mice.

Vilchez V, Turcios L, Butterfield DA, Mitov MI, Coquillard CL, Brandon JA, Cornea V, Gedaly R, Marti F.

Transpl Int. 2017 Oct;30(10):1061-1074. doi: 10.1111/tri.12989. Epub 2017 Jul 31.

35.

Oxidative stress and neurodegeneration.

Zhang J, Butterfield DA.

Brain Res Bull. 2017 Jul;133:1-3. doi: 10.1016/j.brainresbull.2017.04.018. Epub 2017 May 1. No abstract available.

PMID:
28473190
36.

Temperature induces significant changes in both glycolytic reserve and mitochondrial spare respiratory capacity in colorectal cancer cell lines.

Mitov MI, Harris JW, Alstott MC, Zaytseva YY, Evers BM, Butterfield DA.

Exp Cell Res. 2017 May 15;354(2):112-121. doi: 10.1016/j.yexcr.2017.03.046. Epub 2017 Mar 22.

37.

Sorafenib and FH535 in combination act synergistically on hepatocellular carcinoma by targeting cell bioenergetics and mitochondrial function.

Turcios L, Vilchez V, Acosta LF, Poyil P, Butterfield DA, Mitov M, Marti F, Gedaly R.

Dig Liver Dis. 2017 Jun;49(6):697-704. doi: 10.1016/j.dld.2017.01.146. Epub 2017 Jan 19.

PMID:
28179093
38.

Dysregulation of cytokine mediated chemotherapy induced cognitive impairment.

Ren X, St Clair DK, Butterfield DA.

Pharmacol Res. 2017 Mar;117:267-273. doi: 10.1016/j.phrs.2017.01.001. Epub 2017 Jan 4. Review.

PMID:
28063894
39.

Comparative proteomic analyses of the parietal lobe from rhesus monkeys fed a high-fat/sugar diet with and without resveratrol supplementation, relative to a healthy diet: Insights into the roles of unhealthy diets and resveratrol on function.

Swomley AM, Triplett JC, Keeney JT, Warrier G, Pearson KJ, Mattison JA, de Cabo R, Cai J, Klein JB, Butterfield DA.

J Nutr Biochem. 2017 Jan;39:169-179. doi: 10.1016/j.jnutbio.2016.10.006. Epub 2016 Oct 13.

40.

HNE-modified proteins in Down syndrome: Involvement in development of Alzheimer disease neuropathology.

Barone E, Head E, Butterfield DA, Perluigi M.

Free Radic Biol Med. 2017 Oct;111:262-269. doi: 10.1016/j.freeradbiomed.2016.10.508. Epub 2016 Nov 10. Review.

41.

Redox Proteomics: A Key Tool for New Insights into Protein Modification with Relevance to Disease.

Butterfield DA, Perluigi M.

Antioxid Redox Signal. 2017 Mar 1;26(7):277-279. doi: 10.1089/ars.2016.6919. Epub 2017 Jan 6.

42.

Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells.

Palmieri EM, Menga A, Lebrun A, Hooper DC, Butterfield DA, Mazzone M, Castegna A.

Antioxid Redox Signal. 2017 Mar 10;26(8):351-363. doi: 10.1089/ars.2016.6715. Epub 2016 Nov 2.

43.

Role of 4-hydroxy-2-nonenal (HNE) in the pathogenesis of alzheimer disease and other selected age-related neurodegenerative disorders.

Di Domenico F, Tramutola A, Butterfield DA.

Free Radic Biol Med. 2017 Oct;111:253-261. doi: 10.1016/j.freeradbiomed.2016.10.490. Epub 2016 Oct 24. Review.

PMID:
27789292
44.

The Triangle of Death in Alzheimer's Disease Brain: The Aberrant Cross-Talk Among Energy Metabolism, Mammalian Target of Rapamycin Signaling, and Protein Homeostasis Revealed by Redox Proteomics.

Di Domenico F, Barone E, Perluigi M, Butterfield DA.

Antioxid Redox Signal. 2017 Mar 10;26(8):364-387. doi: 10.1089/ars.2016.6759. Epub 2016 Oct 20. Review.

PMID:
27626216
45.

Modulation of GLP-1 signaling as a novel therapeutic approach in the treatment of Alzheimer's disease pathology.

Tramutola A, Arena A, Cini C, Butterfield DA, Barone E.

Expert Rev Neurother. 2017 Jan;17(1):59-75. Epub 2016 Oct 20. Review.

PMID:
27715341
46.

Polyubiquitinylation Profile in Down Syndrome Brain Before and After the Development of Alzheimer Neuropathology.

Tramutola A, Di Domenico F, Barone E, Arena A, Giorgi A, di Francesco L, Schininà ME, Coccia R, Head E, Butterfield DA, Perluigi M.

Antioxid Redox Signal. 2017 Mar 1;26(7):280-298. doi: 10.1089/ars.2016.6686. Epub 2016 Oct 26. Review.

47.

Lipid peroxidation and tyrosine nitration in traumatic brain injury: Insights into secondary injury from redox proteomics.

Butterfield DA, Reed TT.

Proteomics Clin Appl. 2016 Dec;10(12):1191-1204. doi: 10.1002/prca.201600003. Epub 2016 Oct 14. Review.

PMID:
27588567
48.

Hydrogen Limitation and Syntrophic Growth among Natural Assemblages of Thermophilic Methanogens at Deep-sea Hydrothermal Vents.

Topçuoğlu BD, Stewart LC, Morrison HG, Butterfield DA, Huber JA, Holden JF.

Front Microbiol. 2016 Aug 5;7:1240. doi: 10.3389/fmicb.2016.01240. eCollection 2016.

49.

Effect of botanical extracts containing carnosic acid or rosmarinic acid on learning and memory in SAMP8 mice.

Farr SA, Niehoff ML, Ceddia MA, Herrlinger KA, Lewis BJ, Feng S, Welleford A, Butterfield DA, Morley JE.

Physiol Behav. 2016 Oct 15;165:328-38. doi: 10.1016/j.physbeh.2016.08.013. Epub 2016 Aug 12.

50.

Controlled curcumin release via conjugation into PBAE nanogels enhances mitochondrial protection against oxidative stress.

Gupta P, Jordan CT, Mitov MI, Butterfield DA, Hilt JZ, Dziubla TD.

Int J Pharm. 2016 Sep 25;511(2):1012-21. doi: 10.1016/j.ijpharm.2016.07.071. Epub 2016 Aug 2.

Supplemental Content

Loading ...
Support Center