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Items: 1 to 50 of 120

1.

Discovery of Selective M4 Muscarinic Acetylcholine Receptor Agonists with Novel Carbamate Isosteres.

Yang Q, Lachapelle EA, Kablaoui NM, Webb D, Popiolek M, Grimwood S, Kozak R, O'Connor RE, Lazzaro JT, Butler CR, Zhang L.

ACS Med Chem Lett. 2019 May 28;10(6):941-948. doi: 10.1021/acsmedchemlett.9b00106. eCollection 2019 Jun 13.

PMID:
31223452
2.

Education modulates brain maintenance in presymptomatic frontotemporal dementia.

Gazzina S, Grassi M, Premi E, Cosseddu M, Alberici A, Archetti S, Gasparotti R, Van Swieten J, Galimberti D, Sanchez-Valle R, Laforce RJ, Moreno F, Synofzik M, Graff C, Masellis M, Tartaglia MC, Rowe JB, Vandenberghe R, Finger E, Tagliavini F, de Mendonça A, Santana I, Butler CR, Ducharme S, Gerhard A, Danek A, Levin J, Otto M, Frisoni G, Sorbi S, Padovani A, Rohrer JD, Borroni B; Genetic FTD Initiative, GENFI.

J Neurol Neurosurg Psychiatry. 2019 Jun 10. pii: jnnp-2019-320439. doi: 10.1136/jnnp-2019-320439. [Epub ahead of print]

PMID:
31182509
3.

Ultrasound Neuromodulation: A Review of Results, Mechanisms and Safety.

Blackmore J, Shrivastava S, Sallet J, Butler CR, Cleveland RO.

Ultrasound Med Biol. 2019 Jul;45(7):1509-1536. doi: 10.1016/j.ultrasmedbio.2018.12.015. Epub 2019 May 18. Review.

4.

Hippocampal network abnormalities explain amnesia after VGKCC-Ab related autoimmune limbic encephalitis.

Loane C, Argyropoulos GPD, Roca-Fernández A, Lage C, Sheerin F, Ahmed S, Zamboni G, Mackay C, Irani SR, Butler CR.

J Neurol Neurosurg Psychiatry. 2019 May 9. pii: jnnp-2018-320168. doi: 10.1136/jnnp-2018-320168. [Epub ahead of print]

5.

Achieving a person-centered approach to dialysis discontinuation: An historical perspective.

O'Hare AM, Murphy E, Butler CR, Richards CA.

Semin Dial. 2019 Apr 10. doi: 10.1111/sdi.12808. [Epub ahead of print]

PMID:
30968459
6.

Complex Decision Making about Dialysis in Critically Ill Older Adults with AKI.

Butler CR, O'Hare AM.

Clin J Am Soc Nephrol. 2019 Apr 5;14(4):485-487. doi: 10.2215/CJN.01870219. Epub 2019 Mar 21. No abstract available.

PMID:
30898871
7.

Ligand biological activity predicted by cleaning positive and negative chemical correlations.

Lee AA, Yang Q, Bassyouni A, Butler CR, Hou X, Jenkinson S, Price DA.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3373-3378. doi: 10.1073/pnas.1810847116. Epub 2019 Feb 11.

PMID:
30808733
8.

Monitoring neovascularization and integration of decellularized human scaffolds using photoacoustic imaging.

Ogunlade O, Ho JOY, Kalber TL, Hynds RE, Zhang E, Janes SM, Birchall MA, Butler CR, Beard P.

Photoacoustics. 2019 Jan 8;13:76-84. doi: 10.1016/j.pacs.2019.01.001. eCollection 2019 Mar.

9.

A hindbrain inhibitory microcircuit mediates vagally-coordinated glucose regulation.

Boychuk CR, Smith KC, Peterson LE, Boychuk JA, Butler CR, Derera ID, McCarthy JJ, Smith BN.

Sci Rep. 2019 Feb 25;9(1):2722. doi: 10.1038/s41598-019-39490-x.

10.

Lower Extremity Amputation and Health Care Utilization in the Last Year of Life among Medicare Beneficiaries with ESRD.

Butler CR, Schwarze ML, Katz R, Hailpern SM, Kreuter W, Hall YN, Montez Rath ME, O'Hare AM.

J Am Soc Nephrol. 2019 Feb 19. pii: ASN.2018101002. doi: 10.1681/ASN.2018101002. [Epub ahead of print]

PMID:
30782596
11.

Burden of excess mortality after implementation of the new kidney allocation system may be borne disproportionately by middle-aged recipients.

Butler CR, Perkins JD, Johnson CK, Blosser CD, Bakthavatsalam R, Leca N, Sibulesky L.

PLoS One. 2019 Jan 24;14(1):e0210589. doi: 10.1371/journal.pone.0210589. eCollection 2019.

12.

Non-Invasive Longitudinal Bioluminescence Imaging of Human Mesoangioblasts in Bioengineered Esophagi.

Crowley C, Butler CR, Camilli C, Hynds RE, Kolluri KK, Janes SM, De Coppi P, Urbani L.

Tissue Eng Part C Methods. 2019 Feb;25(2):103-113. doi: 10.1089/ten.TEC.2018.0351.

13.

Using a Three-Dimensional Collagen Matrix to Deliver Respiratory Progenitor Cells to Decellularized Trachea In Vivo.

Hamilton NJI, Hynds RE, Gowers KHC, Tait A, Butler CR, Hopper C, Burns AJ, Birchall MA, Lowdell M, Janes SM.

Tissue Eng Part C Methods. 2019 Feb;25(2):93-102. doi: 10.1089/ten.TEC.2018.0241.

14.

Variables Associated With Cardiac Surgical Waitlist Mortality From a Population-Based Cohort.

Senaratne JM, Norris CM, Youngson E, McClure RS, Nagendran J, Butler CR, Meyer SR, Anderson TJ, van Diepen S.

Can J Cardiol. 2019 Jan;35(1):61-67. doi: 10.1016/j.cjca.2018.10.007. Epub 2018 Oct 19.

PMID:
30595184
15.

Impact of contrast echocardiography on accurate discrimination of specific degree of left ventricular systolic dysfunction and comparison with cardiac magnetic resonance imaging.

Alherbish A, Becher H, Alemayehu W, Paterson DI, Butler CR, Anderson TJ, Ezekowitz JA, Shanks M; Alberta HEART investigators.

Echocardiography. 2018 Nov;35(11):1746-1754. doi: 10.1111/echo.14152. Epub 2018 Oct 30.

PMID:
30376596
16.

In Vivo Modulation of Hippocampal Excitability by M4 Muscarinic Acetylcholine Receptor Activator: Implications for Treatment of Alzheimer's Disease and Schizophrenic Patients.

Popiolek M, Mandelblat-Cerf Y, Young D, Garst-Orozco J, Lotarski SM, Stark E, Kramer M, Butler CR, Kozak R.

ACS Chem Neurosci. 2019 Mar 20;10(3):1091-1098. doi: 10.1021/acschemneuro.8b00496. Epub 2018 Oct 26.

PMID:
30335349
17.

Encoding-related brain activity and accelerated forgetting in transient epileptic amnesia.

Atherton KE, Filippini N, Zeman AZJ, Nobre AC, Butler CR.

Cortex. 2019 Jan;110:127-140. doi: 10.1016/j.cortex.2018.04.015. Epub 2018 May 17.

18.

Cross-talk between human airway epithelial cells and 3T3-J2 feeder cells involves partial activation of human MET by murine HGF.

Hynds RE, Gowers KHC, Nigro E, Butler CR, Bonfanti P, Giangreco A, Prêle CM, Janes SM.

PLoS One. 2018 May 17;13(5):e0197129. doi: 10.1371/journal.pone.0197129. eCollection 2018.

19.

Author Correction: Sensorimotor adaptation as a behavioural biomarker of early spinocerebellar ataxia type 6.

Panouillères MTN, Joundi RA, Benitez-Rivero S, Cheeran B, Butler CR, Németh AH, Miall RC, Jenkinson N.

Sci Rep. 2018 Apr 30;8(1):7010. doi: 10.1038/s41598-018-25324-9.

20.

Introduction of a laser safety checklist in the ENT operating theatre-our experience across twenty cases.

Williams SP, Kinshuck AJ, Butler CR, Sandhu GS.

Clin Otolaryngol. 2018 Oct;43(5):1357-1360. doi: 10.1111/coa.13123. Epub 2018 May 22. No abstract available.

PMID:
29688624
21.

Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation.

O'Neill BT, Beck EM, Butler CR, Nolan CE, Gonzales C, Zhang L, Doran SD, Lapham K, Buzon LM, Dutra JK, Barreiro G, Hou X, Martinez-Alsina LA, Rogers BN, Villalobos A, Murray JC, Ogilvie K, LaChapelle EA, Chang C, Lanyon LF, Steppan CM, Robshaw A, Hales K, Boucher GG, Pandher K, Houle C, Ambroise CW, Karanian D, Riddell D, Bales KR, Brodney MA.

J Med Chem. 2018 May 24;61(10):4476-4504. doi: 10.1021/acs.jmedchem.8b00246. Epub 2018 Apr 17.

PMID:
29613789
22.

Swallowing outcomes in children after slide tracheoplasty.

Stewart AJ, Butler CR, Muthialu N, Sell D, Marchant J, Hewitt RJD, Elliott MJ.

Int J Pediatr Otorhinolaryngol. 2018 May;108:85-90. doi: 10.1016/j.ijporl.2018.02.029. Epub 2018 Feb 21.

PMID:
29605373
23.

Accelerated long-term forgetting in asymptomatic APOE ε4 carriers.

Zimmermann JF, Butler CR.

Lancet Neurol. 2018 May;17(5):394-395. doi: 10.1016/S1474-4422(18)30078-4. Epub 2018 Mar 21. No abstract available. Erratum in: Lancet Neurol. 2018 Apr 13;:. Erratum in: Lancet Neurol. 2019 May;18(5):e4.

PMID:
29573908
24.

Aortopexy for the treatment of tracheobronchomalacia in 100 children: a 10-year single-centre experience.

Rijnberg FM, Butler CR, Bieli C, Kumar S, Nouraei R, Asto J, McKavanagh E, de Coppi P, Muthialu N, Elliott MJ, Hewitt RJ.

Eur J Cardiothorac Surg. 2018 Sep 1;54(3):585-592. doi: 10.1093/ejcts/ezy076.

PMID:
29514258
25.

Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation.

McAllister LA, Butler CR, Mente S, O'Neil SV, Fonseca KR, Piro JR, Cianfrogna JA, Foley TL, Gilbert AM, Harris AR, Helal CJ, Johnson DS, Montgomery JI, Nason DM, Noell S, Pandit J, Rogers BN, Samad TA, Shaffer CL, da Silva RG, Uccello DP, Webb D, Brodney MA.

J Med Chem. 2018 Apr 12;61(7):3008-3026. doi: 10.1021/acs.jmedchem.8b00070. Epub 2018 Mar 15.

PMID:
29498843
26.

Accelerated long-term forgetting in presymptomatic autosomal dominant Alzheimer's disease: a cross-sectional study.

Weston PSJ, Nicholas JM, Henley SMD, Liang Y, Macpherson K, Donnachie E, Schott JM, Rossor MN, Crutch SJ, Butler CR, Zeman AZ, Fox NC.

Lancet Neurol. 2018 Feb;17(2):123-132. doi: 10.1016/S1474-4422(17)30434-9. Erratum in: Lancet Neurol. 2018 Apr;17 (4):298.

27.

Inhibition of monoacylglycerol lipase terminates diazepam-resistant status epilepticus in mice and its effects are potentiated by a ketogenic diet.

Terrone G, Pauletti A, Salamone A, Rizzi M, Villa BR, Porcu L, Sheehan MJ, Guilmette E, Butler CR, Piro JR, Samad TA, Vezzani A.

Epilepsia. 2018 Jan;59(1):79-91. doi: 10.1111/epi.13950. Epub 2017 Nov 24.

28.

Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase.

Butler CR, Beck EM, Harris A, Huang Z, McAllister LA, Am Ende CW, Fennell K, Foley TL, Fonseca K, Hawrylik SJ, Johnson DS, Knafels JD, Mente S, Noell GS, Pandit J, Phillips TB, Piro JR, Rogers BN, Samad TA, Wang J, Wan S, Brodney MA.

J Med Chem. 2017 Dec 14;60(23):9860-9873. doi: 10.1021/acs.jmedchem.7b01531. Epub 2017 Dec 5.

PMID:
29148769
29.

Complete Genome Sequences of Mycobacteriophages Clautastrophe, Kingsolomon, Krypton555, and Nicholas.

Chung HM, D'Elia T, Ross JF, Alvarado SM, Brantley MC, Bricker LP, Butler CR, Crist C, Dane JM, Farran BW, Hobbs S, Lapak M, Lovell C, Ludergnani N, McMullen A, Mirza SA, Thrift N, Vaughan DP, Worley G, Ejikemeuwa A, Zaw M, Albritton CF, Bertrand SC, Chaudhry SS, Cheema VA, Do C, Do ML, Duong HM, El-Desoky DH, Green KM, Lee RN, Thornton LA, Vu JM, Zahra MN, Cresawn SG, Stoner TH, Garlena RA, Jacobs-Sera D, Pope WH, Russell DA, Hatfull GF.

Genome Announc. 2017 Nov 9;5(45). pii: e01129-17. doi: 10.1128/genomeA.01129-17.

30.

Brain Injury-Induced Synaptic Reorganization in Hilar Inhibitory Neurons Is Differentially Suppressed by Rapamycin.

Butler CR, Boychuk JA, Smith BN.

eNeuro. 2017 Oct 4;4(5). pii: ENEURO.0134-17.2017. doi: 10.1523/ENEURO.0134-17.2017. eCollection 2017 Sep-Oct.

31.

A comparison of tracheal scaffold strategies for pediatric transplantation in a rabbit model.

Maughan EF, Butler CR, Crowley C, Teoh GZ, den Hondt M, Hamilton NJ, Hynds RE, Lange P, Ansari T, Urbani L, Janes SM, de Coppi P, Birchall MA, Elliott MJ.

Laryngoscope. 2017 Dec;127(12):E449-E457. doi: 10.1002/lary.26611. Epub 2017 Aug 4.

PMID:
28776693
32.

An optimized non-destructive protocol for testing mechanical properties in decellularized rabbit trachea.

Den Hondt M, Vanaudenaerde BM, Maughan EF, Butler CR, Crowley C, Verbeken EK, Verleden SE, Vranckx JJ.

Acta Biomater. 2017 Sep 15;60:291-301. doi: 10.1016/j.actbio.2017.07.035. Epub 2017 Jul 21.

PMID:
28739545
33.

Tracheal Replacement Therapy with a Stem Cell-Seeded Graft: Lessons from Compassionate Use Application of a GMP-Compliant Tissue-Engineered Medicine.

Elliott MJ, Butler CR, Varanou-Jenkins A, Partington L, Carvalho C, Samuel E, Crowley C, Lange P, Hamilton NJ, Hynds RE, Ansari T, Sibbons P, Fierens A, McLaren C, Roebuck D, Wallis C, Muthialu N, Hewitt R, Crabbe D, Janes SM, De Coppi P, Lowdell MW, Birchall MA.

Stem Cells Transl Med. 2017 Jun;6(6):1458-1464. doi: 10.1002/sctm.16-0443.

34.

Sensorimotor adaptation as a behavioural biomarker of early spinocerebellar ataxia type 6.

Panouillères MTN, Joundi RA, Benitez-Rivero S, Cheeran B, Butler CR, Németh AH, Miall RC, Jenkinson N.

Sci Rep. 2017 May 24;7(1):2366. doi: 10.1038/s41598-017-02469-7. Erratum in: Sci Rep. 2018 Apr 30;8(1):7010.

35.

Ex utero intrapartum treatment (EXIT) for upper airway obstruction.

Butler CR, Maughan EF, Pandya P, Hewitt R.

Curr Opin Otolaryngol Head Neck Surg. 2017 Apr;25(2):119-126. doi: 10.1097/MOO.0000000000000343. Review.

PMID:
28267705
36.

Noise exposure among federal wildland fire fighters.

Broyles G, Butler CR, Kardous CA.

J Acoust Soc Am. 2017 Feb;141(2):EL177. doi: 10.1121/1.4976041.

37.

Vacuum-assisted decellularization: an accelerated protocol to generate tissue-engineered human tracheal scaffolds.

Butler CR, Hynds RE, Crowley C, Gowers KH, Partington L, Hamilton NJ, Carvalho C, Platé M, Samuel ER, Burns AJ, Urbani L, Birchall MA, Lowdell MW, De Coppi P, Janes SM.

Biomaterials. 2017 Apr;124:95-105. doi: 10.1016/j.biomaterials.2017.02.001. Epub 2017 Feb 5.

38.

On the nose: Olfactory disturbances in patients with transient epileptic amnesia.

Savage SA, Butler CR, Milton F, Han Y, Zeman AZ.

Epilepsy Behav. 2017 Jan;66:113-119. doi: 10.1016/j.yebeh.2016.09.043. Epub 2016 Dec 28.

39.

Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality.

Butler CR, Ogilvie K, Martinez-Alsina L, Barreiro G, Beck EM, Nolan CE, Atchison K, Benvenuti E, Buzon L, Doran S, Gonzales C, Helal CJ, Hou X, Hsu MH, Johnson EF, Lapham K, Lanyon L, Parris K, O'Neill BT, Riddell D, Robshaw A, Vajdos F, Brodney MA.

J Med Chem. 2017 Jan 12;60(1):386-402. doi: 10.1021/acs.jmedchem.6b01451. Epub 2016 Dec 20.

40.

Transient Epileptic Amnesia over twenty years: Long-term follow-up of a case series with three detailed reports.

Savage SA, Butler CR, Hodges JR, Zeman AZ.

Seizure. 2016 Dec;43:48-55. doi: 10.1016/j.seizure.2016.10.022. Epub 2016 Nov 14.

41.

Validation of the Airway-Dyspnoea-Voice-Swallow (ADVS) scale and Patient-Reported Outcome Measure (PROM) as disease-specific instruments in paediatric laryngotracheal stenosis.

Nouraei SA, Makmur E, Dias A, Butler CR, Nandi R, Elliott MJ, Hewitt R.

Clin Otolaryngol. 2017 Apr;42(2):283-294. doi: 10.1111/coa.12729. Epub 2016 Sep 8.

PMID:
27542317
42.

Slow wave sleep and accelerated forgetting.

Atherton KE, Nobre AC, Lazar AS, Wulff K, Whittaker RG, Dhawan V, Lazar ZI, Zeman AZ, Butler CR.

Cortex. 2016 Nov;84:80-89. doi: 10.1016/j.cortex.2016.08.013. Epub 2016 Sep 12.

43.

Transcatheter Valve-in-Valve: A Cautionary Tale.

Luc JGY, Shanks M, Tyrrell BD, Welsh RC, Butler CR, Meyer SR.

Ann Thorac Surg. 2016 Sep;102(3):e211-e213. doi: 10.1016/j.athoracsur.2016.01.045.

PMID:
27549545
44.

Expansion of Human Airway Basal Stem Cells and Their Differentiation as 3D Tracheospheres.

Hynds RE, Butler CR, Janes SM, Giangreco A.

Methods Mol Biol. 2016 Aug 19. [Epub ahead of print]

PMID:
27539459
45.

Diagnosing young onset dementia can be challenging.

Ahmed S, Baker I, Butler CR.

Practitioner. 2016 May;260(1793):11-7, 2.

PMID:
27382914
46.

Airway tissue engineering for congenital laryngotracheal disease.

Maughan E, Lesage F, Butler CR, Hynds RE, Hewitt R, Janes SM, Deprest JA, Coppi PD.

Semin Pediatr Surg. 2016 Jun;25(3):186-90. doi: 10.1053/j.sempedsurg.2016.02.012. Epub 2016 Feb 22. Review.

PMID:
27301606
47.

Congenital tracheobronchial stenosis.

Hewitt RJ, Butler CR, Maughan EF, Elliott MJ.

Semin Pediatr Surg. 2016 Jun;25(3):144-9. doi: 10.1053/j.sempedsurg.2016.02.007. Epub 2016 Feb 19. Review.

PMID:
27301600
48.

Utility of testing for apraxia and associated features in dementia.

Ahmed S, Baker I, Thompson S, Husain M, Butler CR.

J Neurol Neurosurg Psychiatry. 2016 Nov;87(11):1158-1162. doi: 10.1136/jnnp-2015-312945. Epub 2016 Jun 1.

49.

Memory Impairment at Initial Clinical Presentation in Posterior Cortical Atrophy.

Ahmed S, Baker I, Husain M, Thompson S, Kipps C, Hornberger M, Hodges JR, Butler CR.

J Alzheimers Dis. 2016 Apr 23;52(4):1245-50. doi: 10.3233/JAD-160018.

PMID:
27128371
50.

Advancing the framework for considering the effects of climate change on worker safety and health.

Schulte PA, Bhattacharya A, Butler CR, Chun HK, Jacklitsch B, Jacobs T, Kiefer M, Lincoln J, Pendergrass S, Shire J, Watson J, Wagner GR.

J Occup Environ Hyg. 2016 Nov;13(11):847-65. doi: 10.1080/15459624.2016.1179388.

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