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Items: 1 to 50 of 306

1.

KRAS-Driven Metabolic Rewiring Reveals Novel Actionable Targets in Cancer.

Pupo E, Avanzato D, Middonti E, Bussolino F, Lanzetti L.

Front Oncol. 2019 Aug 30;9:848. doi: 10.3389/fonc.2019.00848. eCollection 2019. Review.

2.

Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5.

Milosevic V, Kopecka J, Salaroglio IC, Libener R, Napoli F, Izzo S, Orecchia S, Ananthanarayanan P, Bironzo P, Grosso F, Tabbò F, Comunanza V, Alexa-Stratulat T, Bussolino F, Righi L, Novello S, Scagliotti GV, Riganti C.

Int J Cancer. 2020 Jan 1;146(1):192-207. doi: 10.1002/ijc.32419. Epub 2019 Jun 4.

PMID:
31107974
3.

Potential Diagnostic and Prognostic Role of Microenvironment in Malignant Pleural Mesothelioma.

Salaroglio IC, Kopecka J, Napoli F, Pradotto M, Maletta F, Costardi L, Gagliasso M, Milosevic V, Ananthanarayanan P, Bironzo P, Tabbò F, Cartia CF, Passone E, Comunanza V, Ardissone F, Ruffini E, Bussolino F, Righi L, Novello S, Di Maio M, Papotti M, Scagliotti GV, Riganti C.

J Thorac Oncol. 2019 Aug;14(8):1458-1471. doi: 10.1016/j.jtho.2019.03.029. Epub 2019 May 9. Erratum in: J Thorac Oncol. 2019 Nov;14(11):2023.

4.

TFEB controls vascular development by regulating the proliferation of endothelial cells.

Doronzo G, Astanina E, Corà D, Chiabotto G, Comunanza V, Noghero A, Neri F, Puliafito A, Primo L, Spampanato C, Settembre C, Ballabio A, Camussi G, Oliviero S, Bussolino F.

EMBO J. 2019 Feb 1;38(3). pii: e98250. doi: 10.15252/embj.201798250. Epub 2018 Dec 27.

5.

Consensus guidelines for the use and interpretation of angiogenesis assays.

Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, Bussolino F, Cakir B, Carmeliet P, Castranova D, Cimpean AM, Cleaver O, Coukos G, Davis GE, De Palma M, Dimberg A, Dings RPM, Djonov V, Dudley AC, Dufton NP, Fendt SM, Ferrara N, Fruttiger M, Fukumura D, Ghesquière B, Gong Y, Griffin RJ, Harris AL, Hughes CCW, Hultgren NW, Iruela-Arispe ML, Irving M, Jain RK, Kalluri R, Kalucka J, Kerbel RS, Kitajewski J, Klaassen I, Kleinmann HK, Koolwijk P, Kuczynski E, Kwak BR, Marien K, Melero-Martin JM, Munn LL, Nicosia RF, Noel A, Nurro J, Olsson AK, Petrova TV, Pietras K, Pili R, Pollard JW, Post MJ, Quax PHA, Rabinovich GA, Raica M, Randi AM, Ribatti D, Ruegg C, Schlingemann RO, Schulte-Merker S, Smith LEH, Song JW, Stacker SA, Stalin J, Stratman AN, Van de Velde M, van Hinsbergh VWM, Vermeulen PB, Waltenberger J, Weinstein BM, Xin H, Yetkin-Arik B, Yla-Herttuala S, Yoder MC, Griffioen AW.

Angiogenesis. 2018 Aug;21(3):425-532. doi: 10.1007/s10456-018-9613-x. Review.

6.

Modulation of Angiopoietin 2 release from endothelial cells and angiogenesis by the synaptic protein Neuroligin 2.

Pergolizzi M, Bizzozero L, Riccitelli E, Pascal D, Samarelli AV, Bussolino F, Arese M.

Biochem Biophys Res Commun. 2018 Jun 18;501(1):165-171. doi: 10.1016/j.bbrc.2018.04.204. Epub 2018 May 4.

PMID:
29709479
7.

Tumor progression: the neuronal input.

Arese M, Bussolino F, Pergolizzi M, Bizzozero L, Pascal D.

Ann Transl Med. 2018 Mar;6(5):89. doi: 10.21037/atm.2018.01.01. Review.

8.

Bloch surface wave enhanced biosensor for the direct detection of Angiopoietin-2 tumor biomarker in human plasma.

Rizzo R, Alvaro M, Danz N, Napione L, Descrovi E, Schmieder S, Sinibaldi A, Rana S, Chandrawati R, Munzert P, Schubert T, Maillart E, Anopchenko A, Rivolo P, Mascioletti A, Förster E, Sonntag F, Stevens MM, Bussolino F, Michelotti F.

Biomed Opt Express. 2018 Jan 8;9(2):529-542. doi: 10.1364/BOE.9.000529. eCollection 2018 Feb 1.

9.

Novel active agents in patients with advanced NSCLC without driver mutations who have progressed after first-line chemotherapy.

Manegold C, Adjei A, Bussolino F, Cappuzzo F, Crino L, Dziadziuszko R, Ettinger D, Fennell D, Kerr K, Le Chevalier T, Leighl N, Papotti M, Paz-Ares L, Pérol M, Peters S, Pirker R, Quoix E, Reck M, Smit E, Vokes E, van Zandwijk N, Zhou C.

ESMO Open. 2017 Jan 13;1(6):e000118. doi: 10.1136/esmoopen-2016-000118. eCollection 2016.

10.

Bromodomain inhibition exerts its therapeutic potential in malignant pleural mesothelioma by promoting immunogenic cell death and changing the tumor immune-environment.

Riganti C, Lingua MF, Salaroglio IC, Falcomatà C, Righi L, Morena D, Picca F, Oddo D, Kopecka J, Pradotto M, Libener R, Orecchia S, Bironzo P, Comunanza V, Bussolino F, Novello S, Scagliotti GV, Di Nicolantonio F, Taulli R.

Oncoimmunology. 2017 Nov 27;7(3):e1398874. doi: 10.1080/2162402X.2017.1398874. eCollection 2018.

11.

PI3K/mTOR inhibition promotes the regression of experimental vascular malformations driven by PIK3CA-activating mutations.

di Blasio L, Puliafito A, Gagliardi PA, Comunanza V, Somale D, Chiaverina G, Bussolino F, Primo L.

Cell Death Dis. 2018 Jan 19;9(2):45. doi: 10.1038/s41419-017-0064-x.

12.

Therapy for Cancer: Strategy of Combining Anti-Angiogenic and Target Therapies.

Comunanza V, Bussolino F.

Front Cell Dev Biol. 2017 Dec 7;5:101. doi: 10.3389/fcell.2017.00101. eCollection 2017. Review.

13.

MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion.

Gagliardi PA, Somale D, Puliafito A, Chiaverina G, di Blasio L, Oneto M, Bianchini P, Bussolino F, Primo L.

J Cell Biol. 2018 Jan 2;217(1):231-249. doi: 10.1083/jcb.201703044. Epub 2017 Nov 21.

14.

Sema3F (Semaphorin 3F) Selectively Drives an Extraembryonic Proangiogenic Program.

Regano D, Visintin A, Clapero F, Bussolino F, Valdembri D, Maione F, Serini G, Giraudo E.

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1710-1721. doi: 10.1161/ATVBAHA.117.308226. Epub 2017 Jul 20.

15.

MicroRNA-mediated regulatory circuits: outlook and perspectives.

Cora' D, Re A, Caselle M, Bussolino F.

Phys Biol. 2017 Jun 6;14(4):045001. doi: 10.1088/1478-3975/aa6f21. Review.

PMID:
28586314
16.

VEGF blockade enhances the antitumor effect of BRAFV600E inhibition.

Comunanza V, Corà D, Orso F, Consonni FM, Middonti E, Di Nicolantonio F, Buzdin A, Sica A, Medico E, Sangiolo D, Taverna D, Bussolino F.

EMBO Mol Med. 2017 Feb;9(2):219-237. doi: 10.15252/emmm.201505774.

17.

Bioengineered tumoral microtissues recapitulate desmoplastic reaction of pancreatic cancer.

Brancato V, Comunanza V, Imparato G, Corà D, Urciuolo F, Noghero A, Bussolino F, Netti PA.

Acta Biomater. 2017 Feb;49:152-166. doi: 10.1016/j.actbio.2016.11.072. Epub 2016 Dec 1.

PMID:
27916739
18.

An Electrical Impedance-Based Method for Quantitative Real-Time Analysis of Semaphorin-Elicited Endothelial Cell Collapse.

Camillo C, Gioelli N, Bussolino F, Serini G.

Methods Mol Biol. 2017;1493:195-207.

PMID:
27787852
19.

Lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity.

Leuci V, Maione F, Rotolo R, Giraudo E, Sassi F, Migliardi G, Todorovic M, Gammaitoni L, Mesiano G, Giraudo L, Luraghi P, Leone F, Bussolino F, Grignani G, Aglietta M, Trusolino L, Bertotti A, Sangiolo D.

J Transl Med. 2016 May 5;14(1):119. doi: 10.1186/s12967-016-0872-2.

20.

BCAM and LAMA5 Mediate the Recognition between Tumor Cells and the Endothelium in the Metastatic Spreading of KRAS-Mutant Colorectal Cancer.

Bartolini A, Cardaci S, Lamba S, Oddo D, Marchiò C, Cassoni P, Amoreo CA, Corti G, Testori A, Bussolino F, Pasqualini R, Arap W, Corà D, Di Nicolantonio F, Marchiò S.

Clin Cancer Res. 2016 Oct 1;22(19):4923-4933. Epub 2016 May 3.

21.

The Neuronal Pentraxin-2 Pathway Is an Unrecognized Target in Human Neuroblastoma, Which Also Offers Prognostic Value in Patients.

Bartolini A, Di Paolo D, Noghero A, Murgia D, Sementa AR, Cilli M, Pasqualini R, Arap W, Bussolino F, Ponzoni M, Pastorino F, Marchiò S.

Cancer Res. 2015 Oct 15;75(20):4265-71. doi: 10.1158/0008-5472.CAN-15-0649. Epub 2015 Aug 20.

22.

Real-time monitoring of cell protrusion dynamics by impedance responses.

Gagliardi PA, Puliafito A, di Blasio L, Chianale F, Somale D, Seano G, Bussolino F, Primo L.

Sci Rep. 2015 May 15;5:10206. doi: 10.1038/srep10206.

23.

The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination.

Maione F, Oliaro-Bosso S, Meda C, Di Nicolantonio F, Bussolino F, Balliano G, Viola F, Giraudo E.

Sci Rep. 2015 Mar 12;5:9054. doi: 10.1038/srep09054.

24.

SPAD aptasensor for the detection of circulating protein biomarkers.

Pasquardini L, Pancheri L, Potrich C, Ferri A, Piemonte C, Lunelli L, Napione L, Comunanza V, Alvaro M, Vanzetti L, Bussolino F, Pederzolli C.

Biosens Bioelectron. 2015 Jun 15;68:500-507. doi: 10.1016/j.bios.2015.01.042. Epub 2015 Jan 19.

PMID:
25636022
25.

PDK1 regulates focal adhesion disassembly by modulating endocytosis of αvβ3 integrin.

di Blasio L, Gagliardi PA, Puliafito A, Sessa R, Seano G, Bussolino F, Primo L.

J Cell Sci. 2015 Mar 1;128(5):863-77. doi: 10.1242/jcs.149294. Epub 2015 Jan 14.

26.

Three-dimensional in vitro assay of endothelial cell invasion and capillary tube morphogenesis.

di Blasio L, Bussolino F, Primo L.

Methods Mol Biol. 2015;1214:41-7. doi: 10.1007/978-1-4939-1462-3_4.

PMID:
25468598
27.

Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.

Seano G, Chiaverina G, Gagliardi PA, di Blasio L, Puliafito A, Bouvard C, Sessa R, Tarone G, Sorokin L, Helley D, Jain RK, Serini G, Bussolino F, Primo L.

Nat Cell Biol. 2014 Oct;16(10):931-41, 1-8. doi: 10.1038/ncb3036. Epub 2014 Sep 14.

28.

Semaphorins in cardiovascular medicine.

Corà D, Astanina E, Giraudo E, Bussolino F.

Trends Mol Med. 2014 Oct;20(10):589-98. doi: 10.1016/j.molmed.2014.07.005. Epub 2014 Aug 22. Review.

29.

PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction.

Gagliardi PA, di Blasio L, Puliafito A, Seano G, Sessa R, Chianale F, Leung T, Bussolino F, Primo L.

J Cell Biol. 2014 Aug 4;206(3):415-34. doi: 10.1083/jcb.201312090.

30.

Angiopoietin-like 7, a novel pro-angiogenetic factor over-expressed in cancer.

Parri M, Pietrovito L, Grandi A, Campagnoli S, De Camilli E, Bianchini F, Marchiò S, Bussolino F, Jin B, Sarmientos P, Grandi G, Viale G, Pileri P, Chiarugi P, Grifantini R.

Angiogenesis. 2014 Oct;17(4):881-96. doi: 10.1007/s10456-014-9435-4. Epub 2014 Jun 6.

PMID:
24903490
31.

Neuroligin 1 induces blood vessel maturation by cooperating with the α6 integrin.

Samarelli AV, Riccitelli E, Bizzozero L, Silveira TN, Seano G, Pergolizzi M, Vitagliano G, Cascone I, Carpentier G, Bottos A, Primo L, Bussolino F, Arese M.

J Biol Chem. 2014 Jul 11;289(28):19466-76. doi: 10.1074/jbc.M113.530972. Epub 2014 May 23. Erratum in: J Biol Chem. 2014 Sep 12;289(37):25475.

32.

Class 3 semaphorin in angiogenesis and lymphangiogenesis.

Bussolino F, Giraudo E, Serini G.

Chem Immunol Allergy. 2014;99:71-88. doi: 10.1159/000353315. Epub 2013 Oct 17. Review.

PMID:
24217603
33.

The V1/V2 loop of HIV-1 gp120 is necessary for Tat binding and consequent modulation of virus entry.

Cardaci S, Soster M, Bussolino F, Marchiò S.

FEBS Lett. 2013 Sep 17;587(18):2943-51. doi: 10.1016/j.febslet.2013.07.039. Epub 2013 Jul 31.

34.

Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings.

Loi M, Di Paolo D, Soster M, Brignole C, Bartolini A, Emionite L, Sun J, Becherini P, Curnis F, Petretto A, Sani M, Gori A, Milanese M, Gambini C, Longhi R, Cilli M, Allen TM, Bussolino F, Arap W, Pasqualini R, Corti A, Ponzoni M, Marchiò S, Pastorino F.

J Control Release. 2013 Sep 10;170(2):233-41. doi: 10.1016/j.jconrel.2013.04.029. Epub 2013 May 25.

35.

Differential regulation of neurexin at glutamatergic and GABAergic synapses.

Pregno G, Frola E, Graziano S, Patrizi A, Bussolino F, Arese M, Sassoè-Pognetto M.

Front Cell Neurosci. 2013 Apr 4;7:35. doi: 10.3389/fncel.2013.00035. eCollection 2013.

36.

A peptide from the extracellular region of the synaptic protein α Neurexin stimulates angiogenesis and the vascular specific tyrosine kinase Tie2.

Graziano S, Marchiò S, Bussolino F, Arese M.

Biochem Biophys Res Commun. 2013 Mar 22;432(4):574-9. doi: 10.1016/j.bbrc.2013.02.045. Epub 2013 Feb 26.

37.

Modeling human tumor angiogenesis in a three-dimensional culture system.

Seano G, Chiaverina G, Gagliardi PA, di Blasio L, Sessa R, Bussolino F, Primo L.

Blood. 2013 May 23;121(21):e129-37. doi: 10.1182/blood-2012-08-452292. Epub 2013 Mar 7.

PMID:
23471306
38.

A fluorescent one-dimensional photonic crystal for label-free biosensing based on BLOCH surface waves.

Frascella F, Ricciardi S, Rivolo P, Moi V, Giorgis F, Descrovi E, Michelotti F, Munzert P, Danz N, Napione L, Alvaro M, Bussolino F.

Sensors (Basel). 2013 Feb 5;13(2):2011-22. doi: 10.3390/s130202011.

39.

Emerging lymphae for the fountain of life.

Marchiò S, Astanina E, Bussolino F.

EMBO J. 2013 Mar 6;32(5):609-11. doi: 10.1038/emboj.2013.13. Epub 2013 Jan 29.

40.

Neuropilin-1 identifies a subset of bone marrow Gr1- monocytes that can induce tumor vessel normalization and inhibit tumor growth.

Carrer A, Moimas S, Zacchigna S, Pattarini L, Zentilin L, Ruozi G, Mano M, Sinigaglia M, Maione F, Serini G, Giraudo E, Bussolino F, Giacca M.

Cancer Res. 2012 Dec 15;72(24):6371-81. doi: 10.1158/0008-5472.CAN-12-0762. Epub 2012 Dec 7.

41.

Class 3 semaphorins: physiological vascular normalizing agents for anti-cancer therapy.

Serini G, Bussolino F, Maione F, Giraudo E.

J Intern Med. 2013 Feb;273(2):138-55. doi: 10.1111/joim.12017. Review.

42.

A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6.

Marchiò S, Soster M, Cardaci S, Muratore A, Bartolini A, Barone V, Ribero D, Monti M, Bovino P, Sun J, Giavazzi R, Asioli S, Cassoni P, Capussotti L, Pucci P, Bugatti A, Rusnati M, Pasqualini R, Arap W, Bussolino F.

EMBO Mol Med. 2012 Nov;4(11):1156-75. doi: 10.1002/emmm.201101164. Epub 2012 Oct 16.

43.

Targeted dual-color silica nanoparticles provide univocal identification of micrometastases in preclinical models of colorectal cancer.

Soster M, Juris R, Bonacchi S, Genovese D, Montalti M, Rampazzo E, Zaccheroni N, Garagnani P, Bussolino F, Prodi L, Marchiò S.

Int J Nanomedicine. 2012;7:4797-807. doi: 10.2147/IJN.S33825. Epub 2012 Sep 5.

44.

3-phosphoinositide-dependent kinase 1 controls breast tumor growth in a kinase-dependent but Akt-independent manner.

Gagliardi PA, di Blasio L, Orso F, Seano G, Sessa R, Taverna D, Bussolino F, Primo L.

Neoplasia. 2012 Aug;14(8):719-31.

45.

The miR-126 regulates angiopoietin-1 signaling and vessel maturation by targeting p85β.

Sessa R, Seano G, di Blasio L, Gagliardi PA, Isella C, Medico E, Cotelli F, Bussolino F, Primo L.

Biochim Biophys Acta. 2012 Oct;1823(10):1925-35. doi: 10.1016/j.bbamcr.2012.07.011. Epub 2012 Jul 31.

46.

The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling.

Sandri C, Caccavari F, Valdembri D, Camillo C, Veltel S, Santambrogio M, Lanzetti L, Bussolino F, Ivaska J, Serini G.

Cell Res. 2012 Oct;22(10):1479-501. doi: 10.1038/cr.2012.110. Epub 2012 Jul 24.

47.

IL-12-dependent innate immunity arrests endothelial cells in G0-G1 phase by a p21(Cip1/Waf1)-mediated mechanism.

Napione L, Strasly M, Meda C, Mitola S, Alvaro M, Doronzo G, Marchiò S, Giraudo E, Primo L, Arese M, Bussolino F.

Angiogenesis. 2012 Dec;15(4):713-25. doi: 10.1007/s10456-012-9286-9. Epub 2012 Jul 15.

PMID:
22797886
48.

Liver X receptor activation reduces angiogenesis by impairing lipid raft localization and signaling of vascular endothelial growth factor receptor-2.

Noghero A, Perino A, Seano G, Saglio E, Lo Sasso G, Veglio F, Primo L, Hirsch E, Bussolino F, Morello F.

Arterioscler Thromb Vasc Biol. 2012 Sep;32(9):2280-8. doi: 10.1161/ATVBAHA.112.250621. Epub 2012 Jun 21.

49.

The synaptic proteins β-neurexin and neuroligin synergize with extracellular matrix-binding vascular endothelial growth factor a during zebrafish vascular development.

Rissone A, Foglia E, Sangiorgio L, Cermenati S, Nicoli S, Cimbro S, Beltrame M, Bussolino F, Cotelli F, Arese M.

Arterioscler Thromb Vasc Biol. 2012 Jul;32(7):1563-72. doi: 10.1161/ATVBAHA.111.243006. Epub 2012 Apr 19.

PMID:
22516065
50.

Unraveling the influence of endothelial cell density on VEGF-A signaling.

Napione L, Pavan S, Veglio A, Picco A, Boffetta G, Celani A, Seano G, Primo L, Gamba A, Bussolino F.

Blood. 2012 Jun 7;119(23):5599-607. doi: 10.1182/blood-2011-11-390666. Epub 2012 Apr 17.

PMID:
22510875

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