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Items: 1 to 50 of 173

1.

Nonclinical safety evaluation of erenumab, a CGRP receptor inhibitor for the prevention of migraine.

Bussiere JL, Davies R, Dean C, Xu C, Kim KH, Vargas HM, Chellman GJ, Balasubramanian G, Rubio-Beltran E, MaassenVanDenBrink A, Monticello TM.

Regul Toxicol Pharmacol. 2019 Aug;106:224-238. doi: 10.1016/j.yrtph.2019.05.013. Epub 2019 May 11. Review.

2.

The skin as a metabolic and immune-competent organ: implications fordrug-induced skin rash.

Sharma A, Saito Y, Hung SI, Naisbitt D, Uetrecht J, Bussiere J.

J Immunotoxicol. 2018 Oct 14:1-12. doi: 10.1080/1547691X.2018.1514444. [Epub ahead of print]

PMID:
30318948
3.

Distribution of RANK and RANK Ligand in Normal Human Tissues as Determined by an Optimized Immunohistochemical Method.

Taylor CR, Branstetter D, Manna E, Dougall WC, Bussiere J, Johnson CW.

Appl Immunohistochem Mol Morphol. 2017 May/Jun;25(5):299-307. doi: 10.1097/PAI.0000000000000503.

PMID:
28248730
4.

Biological Characterization of a Stable Effector Functionless (SEFL) Monoclonal Antibody Scaffold in Vitro.

Liu L, Jacobsen FW, Everds N, Zhuang Y, Yu YB, Li N, Clark D, Nguyen MP, Fort M, Narayanan P, Kim K, Stevenson R, Narhi L, Gunasekaran K, Bussiere JL.

J Biol Chem. 2017 Feb 3;292(5):1876-1883. doi: 10.1074/jbc.M116.748707. Epub 2016 Dec 19.

5.

An open-label study in healthy men to evaluate the risk of seminal fluid transmission of denosumab to pregnant partners.

Sohn W, Lee E, Kankam MK, Egbuna O, Moffat G, Bussiere J, Padhi D, Ng E, Kumar S, Slatter JG.

Br J Clin Pharmacol. 2016 Feb;81(2):362-9. doi: 10.1111/bcp.12798. Epub 2015 Dec 5.

6.

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.

Zheng HF, Forgetta V, Hsu YH, Estrada K, Rosello-Diez A, Leo PJ, Dahia CL, Park-Min KH, Tobias JH, Kooperberg C, Kleinman A, Styrkarsdottir U, Liu CT, Uggla C, Evans DS, Nielson CM, Walter K, Pettersson-Kymmer U, McCarthy S, Eriksson J, Kwan T, Jhamai M, Trajanoska K, Memari Y, Min J, Huang J, Danecek P, Wilmot B, Li R, Chou WC, Mokry LE, Moayyeri A, Claussnitzer M, Cheng CH, Cheung W, Medina-Gómez C, Ge B, Chen SH, Choi K, Oei L, Fraser J, Kraaij R, Hibbs MA, Gregson CL, Paquette D, Hofman A, Wibom C, Tranah GJ, Marshall M, Gardiner BB, Cremin K, Auer P, Hsu L, Ring S, Tung JY, Thorleifsson G, Enneman AW, van Schoor NM, de Groot LC, van der Velde N, Melin B, Kemp JP, Christiansen C, Sayers A, Zhou Y, Calderari S, van Rooij J, Carlson C, Peters U, Berlivet S, Dostie J, Uitterlinden AG, Williams SR, Farber C, Grinberg D, LaCroix AZ, Haessler J, Chasman DI, Giulianini F, Rose LM, Ridker PM, Eisman JA, Nguyen TV, Center JR, Nogues X, Garcia-Giralt N, Launer LL, Gudnason V, Mellström D, Vandenput L, Amin N, van Duijn CM, Karlsson MK, Ljunggren Ö, Svensson O, Hallmans G, Rousseau F, Giroux S, Bussière J, Arp PP, Koromani F, Prince RL, Lewis JR, Langdahl BL, Hermann AP, Jensen JE, Kaptoge S, Khaw KT, Reeve J, Formosa MM, Xuereb-Anastasi A, Åkesson K, McGuigan FE, Garg G, Olmos JM, Zarrabeitia MT, Riancho JA, Ralston SH, Alonso N, Jiang X, Goltzman D, Pastinen T, Grundberg E, Gauguier D, Orwoll ES, Karasik D, Davey-Smith G; AOGC Consortium, Smith AV, Siggeirsdottir K, Harris TB, Zillikens MC, van Meurs JB, Thorsteinsdottir U, Maurano MT, Timpson NJ, Soranzo N, Durbin R, Wilson SG, Ntzani EE, Brown MA, Stefansson K, Hinds DA, Spector T, Cupples LA, Ohlsson C, Greenwood CM; UK10K Consortium, Jackson RD, Rowe DW, Loomis CA, Evans DM, Ackert-Bicknell CL, Joyner AL, Duncan EL, Kiel DP, Rivadeneira F, Richards JB.

Nature. 2015 Oct 1;526(7571):112-7. doi: 10.1038/nature14878. Epub 2015 Sep 14.

7.

Colchicine for Post-Operative Pericardial Effusion: Preliminary Results of the POPE-2 Study.

Meurin P, Lelay-Kubas S, Pierre B, Pereira H, Pavy B, Iliou MC, Bussiere JL, Weber H, Beugin JP, Farrokhi T, Bellemain-Appaix A, Briota L, Tabet JY; French Society of Cardiology.

J Am Coll Cardiol. 2015 Sep 8;66(10):1198-9. doi: 10.1016/j.jacc.2015.05.078. No abstract available.

8.

Colchicine for postoperative pericardial effusion: a multicentre, double-blind, randomised controlled trial.

Meurin P, Lelay-Kubas S, Pierre B, Pereira H, Pavy B, Iliou MC, Bussière JL, Weber H, Beugin JP, Farrokhi T, Bellemain-Appaix A, Briota L, Tabet JY; French Society of Cardiology.

Heart. 2015 Nov;101(21):1711-6. doi: 10.1136/heartjnl-2015-307827. Epub 2015 Jun 15.

PMID:
26076938
9.

PDADMAC flocculation of Chinese hamster ovary cells: enabling a centrifuge-less harvest process for monoclonal antibodies.

McNerney T, Thomas A, Senczuk A, Petty K, Zhao X, Piper R, Carvalho J, Hammond M, Sawant S, Bussiere J.

MAbs. 2015;7(2):413-28. doi: 10.1080/19420862.2015.1007824.

10.

Placental transfer of a fully human IgG2 monoclonal antibody in the cynomolgus monkey, rat, and rabbit: a comparative assessment from during organogenesis to late gestation.

Moffat GJ, Retter MW, Kwon G, Loomis M, Hock MB, Hall C, Bussiere J, Lewis EM, Chellman GJ.

Birth Defects Res B Dev Reprod Toxicol. 2014 Apr;101(2):178-88. doi: 10.1002/bdrb.21105.

PMID:
24753333
11.

Infant cynomolgus monkeys exposed to denosumab in utero exhibit an osteoclast-poor osteopetrotic-like skeletal phenotype at birth and in the early postnatal period.

Boyce RW, Varela A, Chouinard L, Bussiere JL, Chellman GJ, Ominsky MS, Pyrah IT.

Bone. 2014 Jul;64:314-25. doi: 10.1016/j.bone.2014.04.002. Epub 2014 Apr 13.

PMID:
24727159
12.

T-cell-dependent antibody responses in the rat: forms and sources of keyhole limpet hemocyanin matter.

Lebrec H, Hock MB, Sundsmo JS, Mytych DT, Chow H, Carlock LL, Joubert MK, Reindel J, Zhou L, Bussiere JL.

J Immunotoxicol. 2014 Jul-Sep;11(3):213-21. doi: 10.3109/1547691X.2013.822948. Epub 2013 Aug 20.

PMID:
23961896
13.

Reproductive toxicity of denosumab in cynomolgus monkeys.

Bussiere JL, Pyrah I, Boyce R, Branstetter D, Loomis M, Andrews-Cleavenger D, Farman C, Elliott G, Chellman G.

Reprod Toxicol. 2013 Dec;42:27-40. doi: 10.1016/j.reprotox.2013.07.018. Epub 2013 Jul 22.

PMID:
23886817
14.

Assessment of menstrual cycle length in cynomolgus monkeys as a female fertility endpoint of a biopharmaceutical in a 6 month toxicity study.

Bussiere JL, Moffat G, Zhou L, Tarlo KS.

Regul Toxicol Pharmacol. 2013 Aug;66(3):269-78. doi: 10.1016/j.yrtph.2013.05.002. Epub 2013 May 13.

PMID:
23680404
15.

Polyethylene glycol modified FGF21 engineered to maximize potency and minimize vacuole formation.

Xu J, Bussiere J, Yie J, Sickmier A, An P, Belouski E, Stanislaus S, Walker KW.

Bioconjug Chem. 2013 Jun 19;24(6):915-25. doi: 10.1021/bc300603k. Epub 2013 May 9.

PMID:
23594041
16.

An inter-laboratory retrospective analysis of immunotoxicological endpoints in non-human primates: flow cytometry immunophenotyping.

Krejsa CM, Neradilek MB, Polissar NL, Cox N, Clark D, Cowan L, Bussiere J, Lebrec H.

J Immunotoxicol. 2013 Oct-Dec;10(4):361-72. doi: 10.3109/1547691X.2012.755237. Epub 2013 Feb 6. Review.

PMID:
23384295
17.

Myocardial damages and left and right ventricular strains after an extreme mountain ultra-long duration exercise.

Vitiello D, Rupp T, Bussière JL, Robach P, Polge A, Millet GY, Nottin S.

Int J Cardiol. 2013 May 10;165(2):391-2. doi: 10.1016/j.ijcard.2012.08.053. Epub 2012 Sep 30. No abstract available.

PMID:
23031280
18.

Immunogenicity assessment in non-clinical studies.

Swanson SJ, Bussiere J.

Curr Opin Microbiol. 2012 Jun;15(3):337-47. doi: 10.1016/j.mib.2012.05.015. Epub 2012 Jul 4. Review.

PMID:
22770538
19.

An inter-laboratory retrospective analysis of immunotoxicological endpoints in non-human primates: T-cell-dependent antibody responses.

Lebrec H, Cowan L, Lagrou M, Krejsa C, Neradilek MB, Polissar NL, Black L, Bussiere J.

J Immunotoxicol. 2011 Jul-Sep;8(3):238-50. doi: 10.3109/1547691X.2011.587473. Epub 2011 Jun 21.

PMID:
21692639
20.

A novel statistical algorithm for gene expression analysis helps differentiate pregnane X receptor-dependent and independent mechanisms of toxicity.

Mongan MA, Dunn RT, Vonderfecht S, Everds N, Chen G, Su C, Higgins-Garn M, Chen Y, Afshari CA, Williamson TL, Carlock L, Dipalma C, Moss S, Bussiere J, Qualls C, He YD, Hamadeh HK.

PLoS One. 2010 Dec 21;5(12):e15595. doi: 10.1371/journal.pone.0015595.

21.

Survey results on the use of the tissue cross-reactivity immunohistochemistry assay.

Bussiere JL, Leach MW, Price KD, Mounho BJ, Lightfoot-Dunn R.

Regul Toxicol Pharmacol. 2011 Apr;59(3):493-502. doi: 10.1016/j.yrtph.2010.09.017. Epub 2010 Oct 14.

PMID:
20951178
22.

Developmental and reproductive toxicology studies in nonhuman primates.

Chellman GJ, Bussiere JL, Makori N, Martin PL, Ooshima Y, Weinbauer GF.

Birth Defects Res B Dev Reprod Toxicol. 2009 Dec;86(6):446-62. doi: 10.1002/bdrb.20216. Review.

PMID:
20025046
23.

Alternative strategies for toxicity testing of species-specific biopharmaceuticals.

Bussiere JL, Martin P, Horner M, Couch J, Flaherty M, Andrews L, Beyer J, Horvath C.

Int J Toxicol. 2009 May-Jun;28(3):230-53. doi: 10.1177/1091581809337262. Review.

PMID:
19546261
24.

A comparison of effects on reproduction and neonatal development in cynomolgus monkeys given human soluble IL-4R and mice given murine soluble IL-4R.

Carlock LL, Cowan LA, Oneda S, Hoberman A, Wang DD, Hanna R, Bussiere JL.

Regul Toxicol Pharmacol. 2009 Apr;53(3):226-34. doi: 10.1016/j.yrtph.2009.02.001. Epub 2009 Feb 13.

PMID:
19217923
25.

Species selection considerations for preclinical toxicology studies for biotherapeutics.

Bussiere JL.

Expert Opin Drug Metab Toxicol. 2008 Jul;4(7):871-7. doi: 10.1517/17425255.4.7.871 . Review.

PMID:
18624676
26.

Receptor activator of NF-kappa B ligand inhibition suppresses bone resorption and hypercalcemia but does not affect host immune responses to influenza infection.

Miller RE, Branstetter D, Armstrong A, Kennedy B, Jones J, Cowan L, Bussiere J, Dougall WC.

J Immunol. 2007 Jul 1;179(1):266-74.

27.

Chronic dietary alpha-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice.

Quinn JF, Bussiere JR, Hammond RS, Montine TJ, Henson E, Jones RE, Stackman RW Jr.

Neurobiol Aging. 2007 Feb;28(2):213-25. Epub 2006 Jan 31.

PMID:
16448723
28.

Androgen deprivation impairs memory in older men.

Bussiere JR, Beer TM, Neiss MB, Janowsky JS.

Behav Neurosci. 2005 Dec;119(6):1429-37.

PMID:
16420147
29.

Testosterone loss and estradiol administration modify memory in men.

Beer TM, Bland LB, Bussiere JR, Neiss MB, Wersinger EM, Garzotto M, Ryan CW, Janowsky JS.

J Urol. 2006 Jan;175(1):130-5.

PMID:
16406889
30.

Late-onset spondyloarthropathy mimicking reflex sympathetic dystrophy syndrome.

Dubost JJ, Soubrier M, Ristori JM, Guillemot C, Bussière JL, Sauvezie B.

Joint Bone Spine. 2003 Jun;70(3):226-9.

PMID:
12814766
31.
32.

On-line measurement of texture, thickness and plastic strain ratio using laser-ultrasound resonance spectroscopy.

Moreau A, Lévesque D, Lord M, Dubois M, Monchalin JP, Padioleau C, Bussière JF.

Ultrasonics. 2002 Dec;40(10):1047-56.

PMID:
12441181
33.

No changes in the distribution of organisms responsible for septic arthritis over a 20 year period.

Dubost JJ, Soubrier M, De Champs C, Ristori JM, Bussiére JL, Sauvezie B.

Ann Rheum Dis. 2002 Mar;61(3):267-9.

34.

Pamidronate in the treatment of diffuse sclerosing osteomyelitis of the mandible.

Soubrier M, Dubost JJ, Ristori JM, Sauvezie B, Bussière JL.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001 Dec;92(6):637-40.

PMID:
11740481
35.
36.

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions.

Lawrence D, Shahrokh Z, Marsters S, Achilles K, Shih D, Mounho B, Hillan K, Totpal K, DeForge L, Schow P, Hooley J, Sherwood S, Pai R, Leung S, Khan L, Gliniak B, Bussiere J, Smith CA, Strom SS, Kelley S, Fox JA, Thomas D, Ashkenazi A.

Nat Med. 2001 Apr;7(4):383-5. No abstract available.

PMID:
11283636
37.

Safety evaluation of immunomodulatory biopharmaceuticals: can we improve the predictive value of preclinical studies?

Black LE, Green JD, Rener J, Dayan A, Cavagnaro JA, Spindler P, Bussiere JL, Bouchard P, Inoue T, Thomas PT, Essayan DM, Gillett NA, Hart TK, Hastings K, House RV, Latta D, Liminga U, Treacy G, Wierda D.

Hum Exp Toxicol. 2000 Apr;19(4):205-7. No abstract available.

PMID:
10918508
38.

[Rheumatoid arthritis preceding microscopic polyangitis. Report of two cases].

Soubrier M, Le Seaux S, Dubost JJ, Mizony MH, Ristori JM, Bussière JL.

Rev Med Interne. 2000 Jan;21(1):78-82. French.

PMID:
10685457
39.

Safety and antitumor activity of recombinant soluble Apo2 ligand.

Ashkenazi A, Pai RC, Fong S, Leung S, Lawrence DA, Marsters SA, Blackie C, Chang L, McMurtrey AE, Hebert A, DeForge L, Koumenis IL, Lewis D, Harris L, Bussiere J, Koeppen H, Shahrokh Z, Schwall RH.

J Clin Invest. 1999 Jul;104(2):155-62.

40.

Lack of developmental neurotoxicity of MN rgp 120/HIV-1 administered subcutaneously to neonatal rats.

Bussiere JL, Hardy LM, Peterson M, Foss JA, Garman RH, Hoberman AM, Christian MS.

Toxicol Sci. 1999 Mar;48(1):90-9.

PMID:
10330688
41.

The isometric force that induces maximal surface muscle deoxygenation.

Kahn JF, Jouanin JC, Bussière JL, Tinet E, Avrillier S, Ollivier JP, Monod H.

Eur J Appl Physiol Occup Physiol. 1998 Jul;78(2):183-7.

PMID:
9694319
42.

An open study of the anti-TNF alpha agent pentoxifylline in the treatment of rheumatoid arthritis.

Dubost JJ, Soubrier M, Ristori JM, Beaujon G, Oualid T, Bussière JL, Sauvezie B.

Rev Rhum Engl Ed. 1997 Dec;64(12):789-93.

PMID:
9476267
43.

Vasculitis confined to the calves. Report of a case.

Soubrier M, Bangil M, Franc S, Dubost JJ, Ristori JM, Kémény JL, Bussiere JL.

Rev Rhum Engl Ed. 1997 Jun;64(6):414-6. Review.

PMID:
9513615
44.

Response to minocycline of arthritis associated with agammaglobulinemia. A case-report.

Soubrier M, Dubost JJ, Micheau V, Zmantar C, Ristori JM, Bussière JL.

Rev Rhum Engl Ed. 1997 Mar;64(3):195-7.

PMID:
9090770
45.

[Does reactive arthritis caused by Brucella exist? Apropos of 4 cases].

Dubost JJ, Constantin A, Soubrier M, Ristori JM, Cantagrel A, Bussière JL.

Presse Med. 1997 Feb 22;26(5):207-10. French.

PMID:
9122109
46.

[Giant aneurysm of the interventricular septum. Value of imaging techniques].

Revel F, Pernin F, Bussière JL, de Bourayne J, Gandjbakhch I, Ollivier JP.

Arch Mal Coeur Vaiss. 1997 Feb;90(2):285-9. French.

PMID:
9181038
47.

[Erosive polyarthritis triggered by vaccination against hepatitis B].

Soubrier M, Dubost JJ, Bielsa C, Ristori JM, Bussière JL.

Presse Med. 1997 Feb 1;26(2):75. French. No abstract available.

PMID:
9082414
48.

[Idiopathic muscular granulomatosis: apropos of a case].

Bielsa C, Soubrier M, Bussière JL.

Ann Med Interne (Paris). 1997;148(4):329-30. Review. French. No abstract available.

PMID:
9515107
49.

Subchondral insufficiency fracture of the femoral head.

Bangil M, Soubrier M, Dubost JJ, Rami S, Carcanagues Y, Ristori JM, Bussiere JL.

Rev Rhum Engl Ed. 1996 Dec;63(11):859-61. Review.

PMID:
9010975
50.

Reproductive effects of chronic administration of murine interferon-gamma.

Bussiere JL, Hardy LM, Hoberman AM, Foss JA, Christian MS.

Reprod Toxicol. 1996 Sep-Oct;10(5):379-91.

PMID:
8888410

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