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An ultrafast system for signaling mechanical pain in human skin.

Nagi SS, Marshall AG, Makdani A, Jarocka E, Liljencrantz J, Ridderström M, Shaikh S, O'Neill F, Saade D, Donkervoort S, Foley AR, Minde J, Trulsson M, Cole J, Bönnemann CG, Chesler AT, Bushnell MC, McGlone F, Olausson H.

Sci Adv. 2019 Jul 3;5(7):eaaw1297. doi: 10.1126/sciadv.aaw1297. eCollection 2019 Jul.


Is placebo analgesia for heat pain a sensory effect? An exploratory study on minimizing the influence of response bias.

Case LK, Laubacher CM, Richards EA, Grossman M, Atlas LY, Parker S, Bushnell MC.

Neurobiol Pain. 2019 Jan-Jul;5. pii: 100023. doi: 10.1016/j.ynpai.2018.09.001. Epub 2018 Sep 5.


Attitudes and Perceptions Toward Authorized Deception: A Pilot Comparison of Healthy Controls and Fibromyalgia Patients.

Goo SJ, Frangos E, Richards EA, Ceko M, Justement BL, Korb P, Walitt BT, Colloca L, Bushnell MC.

Pain Med. 2019 Apr 22. pii: pnz081. doi: 10.1093/pm/pnz081. [Epub ahead of print]


PIEZO2 mediates injury-induced tactile pain in mice and humans.

Szczot M, Liljencrantz J, Ghitani N, Barik A, Lam R, Thompson JH, Bharucha-Goebel D, Saade D, Necaise A, Donkervoort S, Foley AR, Gordon T, Case L, Bushnell MC, Bönnemann CG, Chesler AT.

Sci Transl Med. 2018 Oct 10;10(462). pii: eaat9892. doi: 10.1126/scitranslmed.aat9892.


Persistent inflammatory pain alters sexually-motivated behavior in male rats.

Pitcher MH, Tarum F, Lehmann M, Bushnell MC.

Behav Brain Res. 2019 Jan 1;356:380-389. doi: 10.1016/j.bbr.2018.09.001. Epub 2018 Sep 8.


Prevalence and Profile of High-Impact Chronic Pain in the United States.

Pitcher MH, Von Korff M, Bushnell MC, Porter L.

J Pain. 2019 Feb;20(2):146-160. doi: 10.1016/j.jpain.2018.07.006. Epub 2018 Aug 7.


Chronic neuropathic pain reduces opioid receptor availability with associated anhedonia in rat.

Thompson SJ, Pitcher MH, Stone LS, Tarum F, Niu G, Chen X, Kiesewetter DO, Schweinhardt P, Bushnell MC.

Pain. 2018 Sep;159(9):1856-1866. doi: 10.1097/j.pain.0000000000001282.


Unique Autonomic Responses to Pain in Yoga Practitioners.

Cotton VA, Low LA, Villemure C, Bushnell MC.

Psychosom Med. 2018 Nov/Dec;80(9):791-798. doi: 10.1097/PSY.0000000000000587.


Do the psychological effects of vagus nerve stimulation partially mediate vagal pain modulation?

Frangos E, Richards EA, Bushnell MC.

Neurobiol Pain. 2017 Jan-Jul;1:37-45. doi: 10.1016/j.ynpai.2017.03.002. Epub 2017 May 17.


Comment on "Molecular and neural basis of contagious itch behavior in mice".

Liljencrantz J, Pitcher MH, Low LA, Bauer L, Bushnell MC.

Science. 2017 Jul 14;357(6347). pii: eaan4749. doi: 10.1126/science.aan4749.


Inhibitory rTMS of secondary somatosensory cortex reduces intensity but not pleasantness of gentle touch.

Case LK, Laubacher CM, Richards EA, Spagnolo PA, Olausson H, Bushnell MC.

Neurosci Lett. 2017 Jul 13;653:84-91. doi: 10.1016/j.neulet.2017.05.006. Epub 2017 May 18.


Encoding of Touch Intensity But Not Pleasantness in Human Primary Somatosensory Cortex.

Case LK, Laubacher CM, Olausson H, Wang B, Spagnolo PA, Bushnell MC.

J Neurosci. 2016 May 25;36(21):5850-60. doi: 10.1523/JNEUROSCI.1130-15.2016.


Restraint training for awake functional brain scanning of rodents can cause long-lasting changes in pain and stress responses.

Low LA, Bauer LC, Pitcher MH, Bushnell MC.

Pain. 2016 Aug;157(8):1761-72. doi: 10.1097/j.pain.0000000000000579.


Touch Perception Altered by Chronic Pain and by Opioid Blockade.

Case LK, Čeko M, Gracely JL, Richards EA, Olausson H, Bushnell MC.

eNeuro. 2016 Mar 10;3(1). pii: ENEURO.0138-15.2016. doi: 10.1523/ENEURO.0138-15.2016. eCollection 2016 Jan-Feb.


Evidence against pain specificity in the dorsal posterior insula.

Davis KD, Bushnell MC, Iannetti GD, St Lawrence K, Coghill R.

F1000Res. 2015 Jul 24;4:362. doi: 10.12688/f1000research.6833.1. eCollection 2015.


Is a Responsive Default Mode Network Required for Successful Working Memory Task Performance?

Čeko M, Gracely JL, Fitzcharles MA, Seminowicz DA, Schweinhardt P, Bushnell MC.

J Neurosci. 2015 Aug 19;35(33):11595-605. doi: 10.1523/JNEUROSCI.0264-15.2015.


Neuroprotective effects of yoga practice: age-, experience-, and frequency-dependent plasticity.

Villemure C, Čeko M, Cotton VA, Bushnell MC.

Front Hum Neurosci. 2015 May 12;9:281. doi: 10.3389/fnhum.2015.00281. eCollection 2015.


Effect of environment on the long-term consequences of chronic pain.

Bushnell MC, Case LK, Ceko M, Cotton VA, Gracely JL, Low LA, Pitcher MH, Villemure C.

Pain. 2015 Apr;156 Suppl 1:S42-9. doi: 10.1097/ Review.


Metabolic brain activity suggestive of persistent pain in a rat model of neuropathic pain.

Thompson SJ, Millecamps M, Aliaga A, Seminowicz DA, Low LA, Bedell BJ, Stone LS, Schweinhardt P, Bushnell MC.

Neuroimage. 2014 May 1;91:344-52. doi: 10.1016/j.neuroimage.2014.01.020. Epub 2014 Jan 21.


Fibromyalgia interacts with age to change the brain.

Ceko M, Bushnell MC, Fitzcharles MA, Schweinhardt P.

Neuroimage Clin. 2013 Sep 6;3:249-60. doi: 10.1016/j.nicl.2013.08.015. eCollection 2013.


Cognitive and emotional control of pain and its disruption in chronic pain.

Bushnell MC, Ceko M, Low LA.

Nat Rev Neurosci. 2013 Jul;14(7):502-11. doi: 10.1038/nrn3516. Epub 2013 May 30. Review.


Insular cortex mediates increased pain tolerance in yoga practitioners.

Villemure C, Ceko M, Cotton VA, Bushnell MC.

Cereb Cortex. 2014 Oct;24(10):2732-40. doi: 10.1093/cercor/bht124. Epub 2013 May 21.


Peripheral nerve injury is associated with chronic, reversible changes in global DNA methylation in the mouse prefrontal cortex.

Tajerian M, Alvarado S, Millecamps M, Vachon P, Crosby C, Bushnell MC, Szyf M, Stone LS.

PLoS One. 2013;8(1):e55259. doi: 10.1371/journal.pone.0055259. Epub 2013 Jan 28.


Altered C-tactile processing in human dynamic tactile allodynia.

Liljencrantz J, Björnsdotter M, Morrison I, Bergstrand S, Ceko M, Seminowicz DA, Cole J, Bushnell MC, Olausson H.

Pain. 2013 Feb;154(2):227-34. doi: 10.1016/j.pain.2012.10.024. Epub 2012 Nov 5.


Nerve injury causes long-term attentional deficits in rats.

Low LA, Millecamps M, Seminowicz DA, Naso L, Thompson SJ, Stone LS, Bushnell MC.

Neurosci Lett. 2012 Nov 7;529(2):103-7. doi: 10.1016/j.neulet.2012.09.027. Epub 2012 Sep 19.


Anatomical and functional enhancements of the insula after loss of large primary somatosensory fibers.

Čeko M, Seminowicz DA, Bushnell MC, Olausson HW.

Cereb Cortex. 2013 Sep;23(9):2017-24. doi: 10.1093/cercor/bhs157. Epub 2012 Jul 20.


Neuroimaging of pain: insights into normal and pathological pain mechanisms.

Schweinhardt P, Bushnell MC.

Neurosci Lett. 2012 Jun 29;520(2):129-30. doi: 10.1016/j.neulet.2012.06.014. No abstract available.


The ventral striatum is implicated in the analgesic effect of mood changes.

Villemure C, Laferrière AC, Bushnell MC.

Pain Res Manag. 2012 Mar-Apr;17(2):69-74.


Rodent functional and anatomical imaging of pain.

Thompson SJ, Bushnell MC.

Neurosci Lett. 2012 Jun 29;520(2):131-9. doi: 10.1016/j.neulet.2012.03.015. Epub 2012 Mar 15. Review.


Fibromyalgia and depression.

Gracely RH, Ceko M, Bushnell MC.

Pain Res Treat. 2012;2012:486590. doi: 10.1155/2012/486590. Epub 2011 Nov 19.


Neurobiology underlying fibromyalgia symptoms.

Ceko M, Bushnell MC, Gracely RH.

Pain Res Treat. 2012;2012:585419. doi: 10.1155/2012/585419. Epub 2011 Oct 27.


Effective treatment of chronic low back pain in humans reverses abnormal brain anatomy and function.

Seminowicz DA, Wideman TH, Naso L, Hatami-Khoroushahi Z, Fallatah S, Ware MA, Jarzem P, Bushnell MC, Shir Y, Ouellet JA, Stone LS.

J Neurosci. 2011 May 18;31(20):7540-50. doi: 10.1523/JNEUROSCI.5280-10.2011.


Autonomic responses to heat pain: Heart rate, skin conductance, and their relation to verbal ratings and stimulus intensity.

Loggia ML, Juneau M, Bushnell MC.

Pain. 2011 Mar;152(3):592-8. doi: 10.1016/j.pain.2010.11.032. Epub 2011 Jan 6.


Pain imaging in health and disease--how far have we come?

Schweinhardt P, Bushnell MC.

J Clin Invest. 2010 Nov;120(11):3788-97. doi: 10.1172/JCI43498. Epub 2010 Nov 1. Review.


Response to heat pain stimulation in idiopathic Parkinson's disease.

Nandhagopal R, Troiano AR, Mak E, Schulzer M, Bushnell MC, Stoessl AJ.

Pain Med. 2010 Jun;11(6):834-40. doi: 10.1111/j.1526-4637.2010.00866.x.


Regional gray matter density changes in brains of patients with irritable bowel syndrome.

Seminowicz DA, Labus JS, Bueller JA, Tillisch K, Naliboff BD, Bushnell MC, Mayer EA.

Gastroenterology. 2010 Jul;139(1):48-57.e2. doi: 10.1053/j.gastro.2010.03.049. Epub 2010 Mar 27.


How neuroimaging studies have challenged us to rethink: is chronic pain a disease?

Tracey I, Bushnell MC.

J Pain. 2009 Nov;10(11):1113-20. doi: 10.1016/j.jpain.2009.09.001. Review.


MRI structural brain changes associated with sensory and emotional function in a rat model of long-term neuropathic pain.

Seminowicz DA, Laferriere AL, Millecamps M, Yu JS, Coderre TJ, Bushnell MC.

Neuroimage. 2009 Sep;47(3):1007-14. doi: 10.1016/j.neuroimage.2009.05.068. Epub 2009 Jun 1.


The anatomy of the mesolimbic reward system: a link between personality and the placebo analgesic response.

Schweinhardt P, Seminowicz DA, Jaeger E, Duncan GH, Bushnell MC.

J Neurosci. 2009 Apr 15;29(15):4882-7. doi: 10.1523/JNEUROSCI.5634-08.2009.


Carriers of recessive WNK1/HSN2 mutations for hereditary sensory and autonomic neuropathy type 2 (HSAN2) are more sensitive to thermal stimuli.

Loggia ML, Bushnell MC, Tétreault M, Thiffault I, Bhérer C, Mohammed NK, Kuchinad AA, Laferrière A, Dicaire MJ, Loisel L, Mogil JS, Brais B.

J Neurosci. 2009 Feb 18;29(7):2162-6. doi: 10.1523/JNEUROSCI.4633-08.2009.


Mood influences supraspinal pain processing separately from attention.

Villemure C, Bushnell MC.

J Neurosci. 2009 Jan 21;29(3):705-15. doi: 10.1523/JNEUROSCI.3822-08.2009.


Increased gray matter density in young women with chronic vulvar pain.

Schweinhardt P, Kuchinad A, Pukall CF, Bushnell MC.

Pain. 2008 Dec;140(3):411-9. doi: 10.1016/j.pain.2008.09.014. Epub 2008 Oct 17.


Effects of psychological state on pain perception in the dental environment.

Loggia ML, Schweinhardt P, Villemure C, Bushnell MC.

J Can Dent Assoc. 2008 Sep;74(7):651-6.


Experimentally induced mood changes preferentially affect pain unpleasantness.

Loggia ML, Mogil JS, Bushnell MC.

J Pain. 2008 Sep;9(9):784-91. doi: 10.1016/j.jpain.2008.03.014. Epub 2008 Jun 6.


Unmyelinated tactile afferents have opposite effects on insular and somatosensory cortical processing.

Olausson HW, Cole J, Vallbo A, McGlone F, Elam M, Krämer HH, Rylander K, Wessberg J, Bushnell MC.

Neurosci Lett. 2008 May 9;436(2):128-32. doi: 10.1016/j.neulet.2008.03.015. Epub 2008 Mar 12.


Fibromyalgia: a disorder of the brain?

Schweinhardt P, Sauro KM, Bushnell MC.

Neuroscientist. 2008 Oct;14(5):415-21. doi: 10.1177/1073858407312521. Epub 2008 Feb 12. Review.


Functional role of unmyelinated tactile afferents in human hairy skin: sympathetic response and perceptual localization.

Olausson H, Cole J, Rylander K, McGlone F, Lamarre Y, Wallin BG, Krämer H, Wessberg J, Elam M, Bushnell MC, Vallbo A.

Exp Brain Res. 2008 Jan;184(1):135-40. Epub 2007 Oct 26.


Empathy hurts: compassion for another increases both sensory and affective components of pain perception.

Loggia ML, Mogil JS, Bushnell MC.

Pain. 2008 May;136(1-2):168-76. Epub 2007 Sep 5.


Fibromyalgia patients show an abnormal dopamine response to pain.

Wood PB, Schweinhardt P, Jaeger E, Dagher A, Hakyemez H, Rabiner EA, Bushnell MC, Chizh BA.

Eur J Neurosci. 2007 Jun;25(12):3576-82.


Accelerated brain gray matter loss in fibromyalgia patients: premature aging of the brain?

Kuchinad A, Schweinhardt P, Seminowicz DA, Wood PB, Chizh BA, Bushnell MC.

J Neurosci. 2007 Apr 11;27(15):4004-7.

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