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Items: 1 to 50 of 119

1.

DEAD-box helicase eIF4A2 inhibits CNOT7 deadenylation activity.

Meijer HA, Schmidt T, Gillen SL, Langlais C, Jukes-Jones R, de Moor CH, Cain K, Wilczynska A, Bushell M.

Nucleic Acids Res. 2019 Jun 10. pii: gkz509. doi: 10.1093/nar/gkz509. [Epub ahead of print]

PMID:
31180491
2.

Leucine zipper and ICAT domain containing (LZIC) protein regulates cell cycle transitions in response to ionizing radiation.

Skalka G, Hall H, Somers J, Bushell M, Willis A, Malewicz M.

Cell Cycle. 2019 May;18(9):963-975. doi: 10.1080/15384101.2019.1601476. Epub 2019 Apr 19.

3.

Challenges and Opportunities in the Management of Onychomycosis.

Christenson JK, Peterson GM, Naunton M, Bushell M, Kosari S, Baby KE, Thomas J.

J Fungi (Basel). 2018 Jul 24;4(3). pii: E87. doi: 10.3390/jof4030087. Review.

4.

Exploring the use of Option Grid™ patient decision aids in a sample of clinics in Poland.

Scalia P, Elwyn G, Barr P, Song J, Zisman-Ilani Y, Lesniak M, Mullin S, Kurek K, Bushell M, Durand MA.

Z Evid Fortbild Qual Gesundhwes. 2018 Jul;134:1-8. doi: 10.1016/j.zefq.2018.04.002. Epub 2018 May 29.

5.

MiR-142-3p is downregulated in aggressive p53 mutant mouse models of pancreatic ductal adenocarcinoma by hypermethylation of its locus.

Godfrey JD, Morton JP, Wilczynska A, Sansom OJ, Bushell MD.

Cell Death Dis. 2018 May 29;9(6):644. doi: 10.1038/s41419-018-0628-4.

6.

TAp73 contributes to the oxidative stress response by regulating protein synthesis.

Marini A, Rotblat B, Sbarrato T, Niklison-Chirou MV, Knight JRP, Dudek K, Jones C, Bushell M, Knight RA, Amelio I, Willis AE, Melino G.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6219-6224. doi: 10.1073/pnas.1718531115. Epub 2018 May 29.

7.

Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair.

Lu WT, Hawley BR, Skalka GL, Baldock RA, Smith EM, Bader AS, Malewicz M, Watts FZ, Wilczynska A, Bushell M.

Nat Commun. 2018 Feb 7;9(1):532. doi: 10.1038/s41467-018-02893-x.

8.

Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf).

Chernova T, Murphy FA, Galavotti S, Sun XM, Powley IR, Grosso S, Schinwald A, Zacarias-Cabeza J, Dudek KM, Dinsdale D, Le Quesne J, Bennett J, Nakas A, Greaves P, Poland CA, Donaldson K, Bushell M, Willis AE, MacFarlane M.

Curr Biol. 2017 Nov 6;27(21):3302-3314.e6. doi: 10.1016/j.cub.2017.09.007.

9.

The emerging role of RNAs in DNA damage repair.

Hawley BR, Lu WT, Wilczynska A, Bushell M.

Cell Death Differ. 2017 Nov;24(11):1989. doi: 10.1038/cdd.2017.146. Epub 2017 Sep 1.

10.

Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice.

Halliday M, Radford H, Zents KAM, Molloy C, Moreno JA, Verity NC, Smith E, Ortori CA, Barrett DA, Bushell M, Mallucci GR.

Brain. 2017 Jun 1;140(6):1768-1783. doi: 10.1093/brain/awx074.

11.

RTN3 Is a Novel Cold-Induced Protein and Mediates Neuroprotective Effects of RBM3.

Bastide A, Peretti D, Knight JR, Grosso S, Spriggs RV, Pichon X, Sbarrato T, Roobol A, Roobol J, Vito D, Bushell M, von der Haar T, Smales CM, Mallucci GR, Willis AE.

Curr Biol. 2017 Mar 6;27(5):638-650. doi: 10.1016/j.cub.2017.01.047. Epub 2017 Feb 23.

12.

The emerging role of RNAs in DNA damage repair.

Hawley BR, Lu WT, Wilczynska A, Bushell M.

Cell Death Differ. 2017 Apr;24(4):580-587. doi: 10.1038/cdd.2017.16. Epub 2017 Feb 24. Review. Erratum in: Cell Death Differ. 2017 Sep 01;:.

13.

A novel role for GSK3β as a modulator of Drosha microprocessor activity and MicroRNA biogenesis.

Fletcher CE, Godfrey JD, Shibakawa A, Bushell M, Bevan CL.

Nucleic Acids Res. 2016 Oct 23. pii: gkw938. [Epub ahead of print]

14.

Maternal Obesity in Pregnancy Developmentally Programs Adipose Tissue Inflammation in Young, Lean Male Mice Offspring.

Alfaradhi MZ, Kusinski LC, Fernandez-Twinn DS, Pantaleão LC, Carr SK, Ferland-McCollough D, Yeo GS, Bushell M, Ozanne SE.

Endocrinology. 2016 Nov;157(11):4246-4256. Epub 2016 Sep 1.

15.

A ribosome-related signature in peripheral blood CLL B cells is linked to reduced survival following treatment.

Sbarrato T, Horvilleur E, Pöyry T, Hill K, Chaplin LC, Spriggs RV, Stoneley M, Wilson L, Jayne S, Vulliamy T, Beck D, Dokal I, Dyer MJ, Yeomans AM, Packham G, Bushell M, Wagner SD, Willis AE.

Cell Death Dis. 2016 Jun 2;7(6):e2249. doi: 10.1038/cddis.2016.148.

16.

Segregation of the Anodic Microbial Communities in a Microbial Fuel Cell Cascade.

Hodgson DM, Smith A, Dahale S, Stratford JP, Li JV, Grüning A, Bushell ME, Marchesi JR, Avignone Rossa C.

Front Microbiol. 2016 May 11;7:699. doi: 10.3389/fmicb.2016.00699. eCollection 2016.

17.

The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration.

Hall AE, Lu WT, Godfrey JD, Antonov AV, Paicu C, Moxon S, Dalmay T, Wilczynska A, Muller PA, Bushell M.

Cell Death Dis. 2016 Apr 7;7:e2184. doi: 10.1038/cddis.2016.91.

18.

Cell-autonomous programming of rat adipose tissue insulin signalling proteins by maternal nutrition.

Martin-Gronert MS, Fernandez-Twinn DS, Bushell M, Siddle K, Ozanne SE.

Diabetologia. 2016 Jun;59(6):1266-75. doi: 10.1007/s00125-016-3905-8. Epub 2016 Mar 10.

19.

Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease.

Chernova T, Sun XM, Powley IR, Galavotti S, Grosso S, Murphy FA, Miles GJ, Cresswell L, Antonov AV, Bennett J, Nakas A, Dinsdale D, Cain K, Bushell M, Willis AE, MacFarlane M.

Cell Death Differ. 2016 Jul;23(7):1152-64. doi: 10.1038/cdd.2015.165. Epub 2016 Feb 19.

20.

A common polymorphism in the 5' UTR of ERCC5 creates an upstream ORF that confers resistance to platinum-based chemotherapy.

Somers J, Wilson LA, Kilday JP, Horvilleur E, Cannell IG, Pöyry TA, Cobbold LC, Kondrashov A, Knight JR, Puget S, Grill J, Grundy RG, Bushell M, Willis AE.

Genes Dev. 2015 Sep 15;29(18):1891-6. doi: 10.1101/gad.261867.115. Epub 2015 Sep 3.

21.

Using Focus Groups to Validate a Pharmacy Vaccination Training Program.

Bushell M, Morrissey H, Ball P.

Pharmacy (Basel). 2015 Jun 12;3(2):39-52. doi: 10.3390/pharmacy3020039.

22.

The role of microRNA in nutritional control.

Nolte-'t Hoen EN, Van Rooij E, Bushell M, Zhang CY, Dashwood RH, James WP, Harris C, Baltimore D.

J Intern Med. 2015 Aug;278(2):99-109. doi: 10.1111/joim.12372. Epub 2015 May 19.

23.

LARP1 post-transcriptionally regulates mTOR and contributes to cancer progression.

Mura M, Hopkins TG, Michael T, Abd-Latip N, Weir J, Aboagye E, Mauri F, Jameson C, Sturge J, Gabra H, Bushell M, Willis AE, Curry E, Blagden SP.

Oncogene. 2015 Sep 24;34(39):5025-36. doi: 10.1038/onc.2014.428. Epub 2014 Dec 22.

24.

Old case, new leads: miRNA links Kaposi's sarcoma-associated herpesvirus with sepsis.

Lu WT, Bushell M.

Cell Death Dis. 2014 Dec 4;5:e1560. doi: 10.1038/cddis.2014.516. No abstract available.

25.

mTORC1-mediated translational elongation limits intestinal tumour initiation and growth.

Faller WJ, Jackson TJ, Knight JR, Ridgway RA, Jamieson T, Karim SA, Jones C, Radulescu S, Huels DJ, Myant KB, Dudek KM, Casey HA, Scopelliti A, Cordero JB, Vidal M, Pende M, Ryazanov AG, Sonenberg N, Meyuhas O, Hall MN, Bushell M, Willis AE, Sansom OJ.

Nature. 2015 Jan 22;517(7535):497-500. doi: 10.1038/nature13896. Epub 2014 Nov 5.

26.

The ever-evolving role of mTOR in translation.

Fonseca BD, Smith EM, Yelle N, Alain T, Bushell M, Pause A.

Semin Cell Dev Biol. 2014 Dec;36:102-12. doi: 10.1016/j.semcdb.2014.09.014. Epub 2014 Sep 27. Review.

PMID:
25263010
27.

The complexity of miRNA-mediated repression.

Wilczynska A, Bushell M.

Cell Death Differ. 2015 Jan;22(1):22-33. doi: 10.1038/cdd.2014.112. Epub 2014 Sep 5. Review.

28.

Regulation of miRNA strand selection: follow the leader?

Meijer HA, Smith EM, Bushell M.

Biochem Soc Trans. 2014 Aug;42(4):1135-40. doi: 10.1042/BST20140142. Review.

PMID:
25110015
29.

Downregulation of IRS-1 in adipose tissue of offspring of obese mice is programmed cell-autonomously through post-transcriptional mechanisms.

Fernandez-Twinn DS, Alfaradhi MZ, Martin-Gronert MS, Duque-Guimaraes DE, Piekarz A, Ferland-McCollough D, Bushell M, Ozanne SE.

Mol Metab. 2014 Jan 20;3(3):325-33. doi: 10.1016/j.molmet.2014.01.007. eCollection 2014 Jun.

30.

The diverse roles of the eIF4A family: you are the company you keep.

Lu WT, Wilczynska A, Smith E, Bushell M.

Biochem Soc Trans. 2014 Feb;42(1):166-72. doi: 10.1042/BST20130161. Review.

PMID:
24450646
31.

miRNAs-19b, -29b-2* and -339-5p show an early and sustained up-regulation in ischemic models of stroke.

Dhiraj DK, Chrysanthou E, Mallucci GR, Bushell M.

PLoS One. 2013 Dec 20;8(12):e83717. doi: 10.1371/journal.pone.0083717. eCollection 2013.

32.

Human 4E-T represses translation of bound mRNAs and enhances microRNA-mediated silencing.

Kamenska A, Lu WT, Kubacka D, Broomhead H, Minshall N, Bushell M, Standart N.

Nucleic Acids Res. 2014 Mar;42(5):3298-313. doi: 10.1093/nar/gkt1265. Epub 2013 Dec 13.

33.

Remodelling of a polypyrimidine tract-binding protein complex during apoptosis activates cellular IRESs.

King HA, Cobbold LC, Pichon X, Pöyry T, Wilson LA, Booden H, Jukes-Jones R, Cain K, Lilley KS, Bushell M, Willis AE.

Cell Death Differ. 2014 Jan;21(1):161-71. doi: 10.1038/cdd.2013.135. Epub 2013 Oct 18.

34.

A role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma.

Horvilleur E, Sbarrato T, Hill K, Spriggs RV, Screen M, Goodrem PJ, Sawicka K, Chaplin LC, Touriol C, Packham G, Potter KN, Dirnhofer S, Tzankov A, Dyer MJ, Bushell M, MacFarlane M, Willis AE.

Leukemia. 2014 May;28(5):1092-102. doi: 10.1038/leu.2013.295. Epub 2013 Oct 18.

35.

Translational repression and eIF4A2 activity are critical for microRNA-mediated gene regulation.

Meijer HA, Kong YW, Lu WT, Wilczynska A, Spriggs RV, Robinson SW, Godfrey JD, Willis AE, Bushell M.

Science. 2013 Apr 5;340(6128):82-5. doi: 10.1126/science.1231197.

36.

Straw N-halamines: evaluation in single and multistage filtration systems.

Ahmed Ael-S, Cavalli G, Bushell ME, Wardell JN, Pedley S, Charles K, Hay JN.

Carbohydr Polym. 2013 Feb 15;92(2):1934-41. doi: 10.1016/j.carbpol.2012.11.036. Epub 2012 Nov 23.

PMID:
23399240
37.

microRNAs in cancer management.

Kong YW, Ferland-McCollough D, Jackson TJ, Bushell M.

Lancet Oncol. 2012 Jun;13(6):e249-58. doi: 10.1016/S1470-2045(12)70073-6. Review.

PMID:
22652233
38.

Sustained translational repression by eIF2α-P mediates prion neurodegeneration.

Moreno JA, Radford H, Peretti D, Steinert JR, Verity N, Martin MG, Halliday M, Morgan J, Dinsdale D, Ortori CA, Barrett DA, Tsaytler P, Bertolotti A, Willis AE, Bushell M, Mallucci GR.

Nature. 2012 May 6;485(7399):507-11. doi: 10.1038/nature11058. Erratum in: Nature.2014 Jul 17;511(7509):370.

39.

Programming of adipose tissue miR-483-3p and GDF-3 expression by maternal diet in type 2 diabetes.

Ferland-McCollough D, Fernandez-Twinn DS, Cannell IG, David H, Warner M, Vaag AA, Bork-Jensen J, Brøns C, Gant TW, Willis AE, Siddle K, Bushell M, Ozanne SE.

Cell Death Differ. 2012 Jun;19(6):1003-12. doi: 10.1038/cdd.2011.183. Epub 2012 Jan 6.

40.

Pedestrian crash trends and potential countermeasures from around the world.

Zegeer CV, Bushell M.

Accid Anal Prev. 2012 Jan;44(1):3-11. doi: 10.1016/j.aap.2010.12.007. Epub 2011 Mar 1.

PMID:
22062330
41.

Acorn: a grid computing system for constraint based modeling and visualization of the genome scale metabolic reaction networks via a web interface.

Sroka J, Bieniasz-Krzywiec L, Gwóźdź S, Leniowski D, Lącki J, Markowski M, Avignone-Rossa C, Bushell ME, McFadden J, Kierzek AM.

BMC Bioinformatics. 2011 May 24;12:196. doi: 10.1186/1471-2105-12-196.

42.

Genome-wide transcriptomic analysis of the response to nitrogen limitation in Streptomyces coelicolor A3(2).

Lewis RA, Shahi SK, Laing E, Bucca G, Efthimiou G, Bushell M, Smith CP.

BMC Res Notes. 2011 Mar 23;4:78. doi: 10.1186/1756-0500-4-78.

43.

The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis.

Kress TR, Cannell IG, Brenkman AB, Samans B, Gaestel M, Roepman P, Burgering BM, Bushell M, Rosenwald A, Eilers M.

Mol Cell. 2011 Feb 18;41(4):445-57. doi: 10.1016/j.molcel.2011.01.023.

44.

SurreyFBA: a command line tool and graphics user interface for constraint-based modeling of genome-scale metabolic reaction networks.

Gevorgyan A, Bushell ME, Avignone-Rossa C, Kierzek AM.

Bioinformatics. 2011 Feb 1;27(3):433-4. doi: 10.1093/bioinformatics/btq679. Epub 2010 Dec 9.

PMID:
21148545
45.

The involvement of microRNAs in Type 2 diabetes.

Ferland-McCollough D, Ozanne SE, Siddle K, Willis AE, Bushell M.

Biochem Soc Trans. 2010 Dec;38(6):1565-70. doi: 10.1042/BST0381565. Review.

PMID:
21118127
46.

New approach to produce water free of bacteria, viruses, and halogens in a recyclable system.

Ahmed Ael-S, Cavalli G, Bushell ME, Wardell JN, Pedley S, Charles K, Hay JN.

Appl Environ Microbiol. 2011 Feb;77(3):847-53. doi: 10.1128/AEM.01645-10. Epub 2010 Nov 29.

47.

Translational regulation of gene expression during conditions of cell stress.

Spriggs KA, Bushell M, Willis AE.

Mol Cell. 2010 Oct 22;40(2):228-37. doi: 10.1016/j.molcel.2010.09.028. Review.

48.

LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing.

James V, Zhang Y, Foxler DE, de Moor CH, Kong YW, Webb TM, Self TJ, Feng Y, Lagos D, Chu CY, Rana TM, Morley SJ, Longmore GD, Bushell M, Sharp TV.

Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12499-504. doi: 10.1073/pnas.0914987107. Epub 2010 Jun 28.

49.

Regulation of Myc by miR-34c: A mechanism to prevent genomic instability?

Cannell IG, Bushell M.

Cell Cycle. 2010 Jul 15;9(14):2726-30. Epub 2010 Jul 27. Review.

PMID:
20603603
50.

Inhibition of hypoxia-inducible factor-1alpha (HIF-1alpha) protein synthesis by DNA damage inducing agents.

Lou JJ, Chua YL, Chew EH, Gao J, Bushell M, Hagen T.

PLoS One. 2010 May 7;5(5):e10522. doi: 10.1371/journal.pone.0010522.

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