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Items: 42

1.

Calculation of upper esophageal sphincter restitution time from high resolution manometry data using machine learning.

Jungheim M, Busche A, Miller S, Schilling N, Schmidt-Thieme L, Ptok M.

Physiol Behav. 2016 Oct 15;165:413-24. doi: 10.1016/j.physbeh.2016.08.005. Epub 2016 Aug 10.

PMID:
27521686
2.

Van der Woude and Popliteal Pterygium Syndromes: Broad intrafamilial variability in a three generation family with mutation in IRF6.

Busche A, Hehr U, Sieg P, Gillessen-Kaesbach G.

Am J Med Genet A. 2016 Sep;170(9):2404-7. doi: 10.1002/ajmg.a.37791. Epub 2016 Jun 10.

PMID:
27286731
3.

In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity.

Halle S, Keyser KA, Stahl FR, Busche A, Marquardt A, Zheng X, Galla M, Heissmeyer V, Heller K, Boelter J, Wagner K, Bischoff Y, Martens R, Braun A, Werth K, Uvarovskii A, Kempf H, Meyer-Hermann M, Arens R, Kremer M, Sutter G, Messerle M, Förster R.

Immunity. 2016 Feb 16;44(2):233-45. doi: 10.1016/j.immuni.2016.01.010. Epub 2016 Feb 9.

4.

Trends of patient referral to a memory clinic and towards earlier diagnosis from 1985-2009.

Grimmer T, Beringer S, Kehl V, Alexopoulos P, Busche A, Förstl H, Goldhardt O, Natale B, Ortner M, Peters H, Riedl L, Roßmeier C, Valentin W, Diehl-Schmid J, Kurz A.

Int Psychogeriatr. 2015 Dec;27(12):1939-44. doi: 10.1017/S104161021500157X. Epub 2015 Oct 2.

PMID:
26424328
5.

Assembling a Correctly Folded and Functional Heptahelical Membrane Protein by Protein Trans-splicing.

Mehler M, Eckert CE, Busche A, Kulhei J, Michaelis J, Becker-Baldus J, Wachtveitl J, Dötsch V, Glaubitz C.

J Biol Chem. 2015 Nov 13;290(46):27712-22. doi: 10.1074/jbc.M115.681205. Epub 2015 Sep 24.

6.

Genetic dosage compensation via co-occurrence of PMP22 duplication and PMP22 deletion.

Hirt N, Eggermann K, Hyrenbach S, Lambeck J, Busche A, Fischer J, Rudnik-Schöneborn S, Gaspar H.

Neurology. 2015 Apr 14;84(15):1605-6. doi: 10.1212/WNL.0000000000001470. Epub 2015 Mar 20. No abstract available.

PMID:
25795643
7.

Variants in CUL4B are associated with cerebral malformations.

Vulto-van Silfhout AT, Nakagawa T, Bahi-Buisson N, Haas SA, Hu H, Bienek M, Vissers LE, Gilissen C, Tzschach A, Busche A, Müsebeck J, Rump P, Mathijssen IB, Avela K, Somer M, Doagu F, Philips AK, Rauch A, Baumer A, Voesenek K, Poirier K, Vigneron J, Amram D, Odent S, Nawara M, Obersztyn E, Lenart J, Charzewska A, Lebrun N, Fischer U, Nillesen WM, Yntema HG, Järvelä I, Ropers HH, de Vries BB, Brunner HG, van Bokhoven H, Raymond FL, Willemsen MA, Chelly J, Xiong Y, Barkovich AJ, Kalscheuer VM, Kleefstra T, de Brouwer AP.

Hum Mutat. 2015 Jan;36(1):106-17. doi: 10.1002/humu.22718.

8.

Large homozygous RAB3GAP1 gene microdeletion causes Warburg micro syndrome 1.

Picker-Minh S, Busche A, Hartmann B, Spors B, Klopocki E, Hübner C, Horn D, Kaindl AM.

Orphanet J Rare Dis. 2014 Oct 21;9:113. doi: 10.1186/s13023-014-0113-9.

9.

Nodular inflammatory foci are sites of T cell priming and control of murine cytomegalovirus infection in the neonatal lung.

Stahl FR, Heller K, Halle S, Keyser KA, Busche A, Marquardt A, Wagner K, Boelter J, Bischoff Y, Kremmer E, Arens R, Messerle M, Förster R.

PLoS Pathog. 2013;9(12):e1003828. doi: 10.1371/journal.ppat.1003828. Epub 2013 Dec 12.

10.

Superior induction and maintenance of protective CD8 T cells in mice infected with mouse cytomegalovirus vector expressing RAE-1γ.

Trsan T, Busche A, Abram M, Wensveen FM, Lemmermann NA, Arapovic M, Babic M, Tomic A, Golemac M, Brinkmann MM, Jäger W, Oxenius A, Polic B, Krmpotic A, Messerle M, Jonjic S.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16550-5. doi: 10.1073/pnas.1310215110. Epub 2013 Sep 19.

11.

SPLICEFINDER - a fast and easy screening method for active protein trans-splicing positions.

Zettler J, Eppmann S, Busche A, Dikovskaya D, Dötsch V, Mootz HD, Sonntag T.

PLoS One. 2013 Sep 2;8(9):e72925. doi: 10.1371/journal.pone.0072925. eCollection 2013.

12.

Priming of CD8+ T cells against cytomegalovirus-encoded antigens is dominated by cross-presentation.

Busche A, Jirmo AC, Welten SP, Zischke J, Noack J, Constabel H, Gatzke AK, Keyser KA, Arens R, Behrens GM, Messerle M.

J Immunol. 2013 Mar 15;190(6):2767-77. doi: 10.4049/jimmunol.1200966. Epub 2013 Feb 6.

13.

Novel mutations including deletions of the entire OFD1 gene in 30 families with type 1 orofaciodigital syndrome: a study of the extensive clinical variability.

Bisschoff IJ, Zeschnigk C, Horn D, Wellek B, Rieß A, Wessels M, Willems P, Jensen P, Busche A, Bekkebraten J, Chopra M, Hove HD, Evers C, Heimdal K, Kaiser AS, Kunstmann E, Robinson KL, Linné M, Martin P, McGrath J, Pradel W, Prescott KE, Roesler B, Rudolf G, Siebers-Renelt U, Tyshchenko N, Wieczorek D, Wolff G, Dobyns WB, Morris-Rosendahl DJ.

Hum Mutat. 2013 Jan;34(1):237-47. doi: 10.1002/humu.22224. Epub 2012 Oct 17.

14.

Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection.

Rodríguez-Martín S, Kropp KA, Wilhelmi V, Lisnic VJ, Hsieh WY, Blanc M, Livingston A, Busche A, Tekotte H, Messerle M, Auer M, Fraser I, Jonjic S, Angulo A, Reddehase MJ, Ghazal P.

PLoS Pathog. 2012;8(8):e1002901. doi: 10.1371/journal.ppat.1002901. Epub 2012 Aug 30.

15.

Characterization of molecular interactions between ACP and halogenase domains in the Curacin A polyketide synthase.

Busche A, Gottstein D, Hein C, Ripin N, Pader I, Tufar P, Eisman EB, Gu L, Walsh CT, Sherman DH, Löhr F, Güntert P, Dötsch V.

ACS Chem Biol. 2012 Feb 17;7(2):378-86. doi: 10.1021/cb200352q. Epub 2011 Dec 15.

16.

Misregulation of mitotic chromosome segregation in a new type of autosomal recessive primary microcephaly.

Marchal JA, Ghani M, Schindler D, Gavvovidis I, Winkler T, Esquitino V, Sternberg N, Busche A, Krawitz P, Hecht J, Robinson P, Mundlos S, Graul-Neumann L, Sperling K, Trimborn M, Neitzel H.

Cell Cycle. 2011 Sep 1;10(17):2967-77. Epub 2011 Sep 1.

PMID:
21857152
17.

Reversible inhibition of murine cytomegalovirus replication by gamma interferon (IFN-γ) in primary macrophages involves a primed type I IFN-signaling subnetwork for full establishment of an immediate-early antiviral state.

Kropp KA, Robertson KA, Sing G, Rodriguez-Martin S, Blanc M, Lacaze P, Hassim MF, Khondoker MR, Busche A, Dickinson P, Forster T, Strobl B, Mueller M, Jonjic S, Angulo A, Ghazal P.

J Virol. 2011 Oct;85(19):10286-99. doi: 10.1128/JVI.00373-11. Epub 2011 Jul 20.

18.

The mouse cytomegalovirus glycoprotein m155 inhibits CD40 expression and restricts CD4 T cell responses.

Loewendorf AI, Steinbrueck L, Peter C, Busche A, Benedict CA, Kay-Jackson PC.

J Virol. 2011 May;85(10):5208-12. doi: 10.1128/JVI.02178-10. Epub 2011 Mar 16.

19.

Microdeletions of chromosome 7p21, including TWIST1, associated with significant microcephaly, facial dysmorphism, and short stature.

Busche A, Graul-Neumann LM, Zweier C, Rauch A, Klopocki E, Horn D.

Eur J Med Genet. 2011 May-Jun;54(3):256-61. doi: 10.1016/j.ejmg.2011.02.002. Epub 2011 Feb 17.

PMID:
21333765
20.

Single cell detection of latent cytomegalovirus reactivation in host tissue.

Marquardt A, Halle S, Seckert CK, Lemmermann NA, Veres TZ, Braun A, Maus UA, Förster R, Reddehase MJ, Messerle M, Busche A.

J Gen Virol. 2011 Jun;92(Pt 6):1279-91. doi: 10.1099/vir.0.029827-0. Epub 2011 Feb 16.

PMID:
21325477
21.

Genetic labeling reveals altered turnover and stability of innate lymphocytes in latent mouse cytomegalovirus infection.

Busche A, Schmitz S, Fleige H, Robbins SH, Walzer T, Stewart CA, Förster R, Messerle M, Prinz I.

J Immunol. 2011 Mar 1;186(5):2918-25. doi: 10.4049/jimmunol.1003232. Epub 2011 Jan 26.

22.

Recombinant mouse cytomegalovirus expressing a ligand for the NKG2D receptor is attenuated and has improved vaccine properties.

Slavuljica I, Busche A, Babić M, Mitrović M, Gašparović I, Cekinović D, Markova Car E, Pernjak Pugel E, Ciković A, Lisnić VJ, Britt WJ, Koszinowski U, Messerle M, Krmpotić A, Jonjić S.

J Clin Invest. 2010 Dec;120(12):4532-45. doi: 10.1172/JCI43961. Epub 2010 Nov 22.

23.

Establishment of a mouse model with misregulated chromosome condensation due to defective Mcph1 function.

Trimborn M, Ghani M, Walther DJ, Dopatka M, Dutrannoy V, Busche A, Meyer F, Nowak S, Nowak J, Zabel C, Klose J, Esquitino V, Garshasbi M, Kuss AW, Ropers HH, Mueller S, Poehlmann C, Gavvovidis I, Schindler D, Sperling K, Neitzel H.

PLoS One. 2010 Feb 16;5(2):e9242. doi: 10.1371/journal.pone.0009242.

24.

Segmental isotopic labeling of a central domain in a multidomain protein by protein trans-splicing using only one robust DnaE intein.

Busche AE, Aranko AS, Talebzadeh-Farooji M, Bernhard F, Dötsch V, Iwaï H.

Angew Chem Int Ed Engl. 2009;48(33):6128-31. doi: 10.1002/anie.200901488. No abstract available.

PMID:
19591176
25.

Conditional and reversible disruption of essential herpesvirus proteins.

Glass M, Busche A, Wagner K, Messerle M, Borst EM.

Nat Methods. 2009 Aug;6(8):577-9. doi: 10.1038/nmeth.1346. Epub 2009 Jul 5.

PMID:
19578384
26.

The mouse cytomegalovirus immediate-early 1 gene is not required for establishment of latency or for reactivation in the lungs.

Busche A, Marquardt A, Bleich A, Ghazal P, Angulo A, Messerle M.

J Virol. 2009 May;83(9):4030-8. doi: 10.1128/JVI.02520-08. Epub 2009 Feb 11.

27.

Neonatal manifestation of multiple sulfatase deficiency.

Busche A, Hennermann JB, Bürger F, Proquitté H, Dierks T, von Arnim-Baas A, Horn D.

Eur J Pediatr. 2009 Aug;168(8):969-73. doi: 10.1007/s00431-008-0871-2. Epub 2008 Dec 10. Review.

PMID:
19066960
28.

In vivo competence of murine cytomegalovirus under the control of the human cytomegalovirus major immediate-early enhancer in the establishment of latency and reactivation.

Gustems M, Busche A, Messerle M, Ghazal P, Angulo A.

J Virol. 2008 Oct;82(20):10302-7. doi: 10.1128/JVI.01255-08. Epub 2008 Aug 6.

29.

A cryptic unbalanced translocation t(2;9)(p25.2;q34.3) causes the phenotype of 9q subtelomeric deletion syndrome and additional exophthalmos and joint contractures.

Busche A, Klopocki E, Ullmann R, Mundlos S, Horn D.

Eur J Med Genet. 2008 Nov-Dec;51(6):615-21. doi: 10.1016/j.ejmg.2008.06.006. Epub 2008 Jul 12.

PMID:
18674647
30.

Phenotypes of major immediate-early gene mutants of mouse cytomegalovirus.

Busche A, Angulo A, Kay-Jackson P, Ghazal P, Messerle M.

Med Microbiol Immunol. 2008 Jun;197(2):233-40. doi: 10.1007/s00430-008-0076-3. Epub 2008 Feb 1. Review.

PMID:
18239940
31.

A short ultraconserved sequence drives transcription from an alternate FBN1 promoter.

Guo G, Bauer S, Hecht J, Schulz MH, Busche A, Robinson PN.

Int J Biochem Cell Biol. 2008;40(4):638-50. Epub 2007 Oct 2.

PMID:
17996480
32.

Administration of oral methylphenidate during adolescence prevents suppressive development of dopamine projections into prefrontal cortex and amygdala after an early pharmacological challenge in gerbils.

Grund T, Teuchert-Noodt G, Busche A, Neddens J, Brummelte S, Moll GH, Dawirs RR.

Brain Res. 2007 Oct 24;1176:124-32. Epub 2007 Aug 21.

PMID:
17900540
33.

Malignant and non-malignant lung tissue areas are differentially populated by natural killer cells and regulatory T cells in non-small cell lung cancer.

Esendagli G, Bruderek K, Goldmann T, Busche A, Branscheid D, Vollmer E, Brandau S.

Lung Cancer. 2008 Jan;59(1):32-40. Epub 2007 Sep 7.

PMID:
17825949
34.
35.

The maturation of the acetylcholine system in the dentate gyrus of gerbils (Meriones unguiculatus) is affected by epigenetic factors.

Busche A, Bagorda A, Lehmann K, Neddens J, Teuchert-Noodt G.

J Neural Transm (Vienna). 2006 Feb;113(2):113-24. Epub 2005 Jun 15.

PMID:
15959847
36.

Anti-cancer and antibacterial trioxacarcins with high anti-malaria activity from a marine Streptomycete and their absolute stereochemistry.

Maskey RP, Helmke E, Kayser O, Fiebig HH, Maier A, Busche A, Laatsch H.

J Antibiot (Tokyo). 2004 Dec;57(12):771-9.

37.
38.

Immunodominant PstS1 antigen of mycobacterium tuberculosis is a potent biological response modifier for the treatment of bladder cancer.

Sänger C, Busche A, Bentien G, Spallek R, Jonas F, Böhle A, Singh M, Brandau S.

BMC Cancer. 2004 Nov 26;4:86.

39.

Postnatal maturation of cortical serotonin lateral asymmetry in gerbils is vulnerable to both environmental and pharmacological epigenetic challenges.

Neddens J, Dawirs RR, Bagorda F, Busche A, Horstmann S, Teuchert-Noodt G.

Brain Res. 2004 Sep 24;1021(2):200-8.

PMID:
15342268
40.

Developmentally induced imbalance of dopaminergic fibre densities in limbic brain regions of gerbils ( Meriones unguiculatus).

Busche A, Polascheck D, Lesting J, Neddens J, Teuchert-Noodt G.

J Neural Transm (Vienna). 2004 Apr;111(4):451-63. Epub 2004 Feb 17.

PMID:
15057515
41.

Epigenetic factors differentially influence postnatal maturation of serotonin (5-HT) innervation in cerebral cortex of gerbils: interaction of rearing conditions and early methamphetamine challenge.

Neddens J, Bagorda F, Busche A, Horstmann S, Moll GH, Dawirs RR, Teuchert-Noodt G.

Brain Res Dev Brain Res. 2003 Dec 19;146(1-2):119-30.

PMID:
14643018
42.

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