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Rhodococcus as A Versatile Biocatalyst in Organic Synthesis.

Busch H, Hagedoorn PL, Hanefeld U.

Int J Mol Sci. 2019 Sep 26;20(19). pii: E4787. doi: 10.3390/ijms20194787. Review.


Blue light (λ=453 nm) nitric oxide dependently induces β-endorphin production of human skin keratinocytes in-vitro and increases systemic β-endorphin levels in humans in-vivo.

Albers I, Zernickel E, Stern M, Broja M, Busch HL, Heiss C, Grotheer V, Windolf J, Suschek CV.

Free Radic Biol Med. 2019 Sep 22;145:78-86. doi: 10.1016/j.freeradbiomed.2019.09.022. [Epub ahead of print]


SNAIL1 employs β-Catenin-LEF1 complexes to control colorectal cancer cell invasion and proliferation.

Freihen V, Rönsch K, Mastroianni J, Frey P, Rose K, Boerries M, Zeiser R, Busch H, Hecht A.

Int J Cancer. 2019 Aug 28. doi: 10.1002/ijc.32644. [Epub ahead of print]


[Freiburg Cardiac Arrest Receiving Team (CART) : Interdisciplinary solution for the acute management of non-traumatic out-of-hospital cardiac arrest].

Busch HJ, Schmid B, Kron J, Fink K, Busche C, Danner T, Veits O, Gottlieb D, Benk C, Trummer G, Meyer-Först S, Kopp S, Schwab W, Wengenmayer T, Biever P.

Med Klin Intensivmed Notfmed. 2019 Jul 30. doi: 10.1007/s00063-019-0598-z. [Epub ahead of print] German.


Maternally Inherited Differences within Mitochondrial Complex I Control Murine Healthspan.

Hirose M, Schilf P, Zarse K, Busch H, Fuellen G, Jöhren O, Köhling R, König IR, Richer B, Rupp J, Schwaninger M, Seeger K, Sina C, Ristow M, Ibrahim SM.

Genes (Basel). 2019 Jul 13;10(7). pii: E532. doi: 10.3390/genes10070532.


Oxidative stress as candidate therapeutic target to overcome microenvironmental protection of CLL.

Yosifov DY, Idler I, Bhattacharya N, Reichenzeller M, Close V, Ezerina D, Scheffold A, Jebaraj BMC, Kugler S, Bloehdorn J, Bahlo J, Robrecht S, Eichhorst B, Fischer K, Weigel A, Busch H, Lichter P, Döhner H, Dick TP, Stilgenbauer S, Mertens D.

Leukemia. 2019 Jul 12. doi: 10.1038/s41375-019-0513-x. [Epub ahead of print]


[Bleeding as a Leading Symptom in the Interdisciplinary Emergency Department].

Schmid B, Hodel K, Busch HJ.

Dtsch Med Wochenschr. 2019 Jul;144(13):876-883. doi: 10.1055/a-0747-7175. Epub 2019 Jun 28. German.


Age-associated outcomes after survived out-of-hospital cardiac arrest and subsequent target temperature management.

Pätz T, Stelzig K, Pfeifer R, Pittl U, Thiele H, Busch HJ, Reinhard I, Wolfrum S.

Acta Anaesthesiol Scand. 2019 Sep;63(8):1079-1088. doi: 10.1111/aas.13386. Epub 2019 Jun 17.


[Postcardiac arrest treatment guide].

Storm C, Behringer W, Wolfrum S, Michels G, Fink K, Kill C, Arrich J, Leithner C, Ploner C, Busch HJ.

Med Klin Intensivmed Notfmed. 2019 Jun 13. doi: 10.1007/s00063-019-0591-6. [Epub ahead of print] Review. German.


Unclear Information About a Treatment Recommendation.

Leidel BA, Dormann H, Busch HJ, Kluge S.

Dtsch Arztebl Int. 2019 Apr 26;116(17):296. doi: 10.3238/arztebl.2019.0296a. No abstract available.


Optimization of reference gene panels for gene expression analysis in preclinical models of inflammatory skin diseases.

Braun A, Sezin T, Bezdek S, Doxastaki I, Zillikens D, Busch HS, Sadik CD.

Exp Dermatol. 2019 Aug;28(8):985-988. doi: 10.1111/exd.13989. Epub 2019 Jul 3.


TGFβ-induced cytoskeletal remodeling mediates elevation of cell stiffness and invasiveness in NSCLC.

Gladilin E, Ohse S, Boerries M, Busch H, Xu C, Schneider M, Meister M, Eils R.

Sci Rep. 2019 May 21;9(1):7667. doi: 10.1038/s41598-019-43409-x.


A Natural mtDNA Polymorphism in Complex III Is a Modifier of Healthspan in Mice.

Hirose M, Künstner A, Schilf P, Tietjen AK, Jöhren O, Huebbe P, Rimbach G, Rupp J, Schwaninger M, Busch H, Ibrahim SM.

Int J Mol Sci. 2019 May 13;20(9). pii: E2359. doi: 10.3390/ijms20092359.


Effect of Trans-Nasal Evaporative Intra-arrest Cooling on Functional Neurologic Outcome in Out-of-Hospital Cardiac Arrest: The PRINCESS Randomized Clinical Trial.

Nordberg P, Taccone FS, Truhlar A, Forsberg S, Hollenberg J, Jonsson M, Cuny J, Goldstein P, Vermeersch N, Higuet A, Jiménes FC, Ortiz FR, Williams J, Desruelles D, Creteur J, Dillenbeck E, Busche C, Busch HJ, Ringh M, Konrad D, Peterson J, Vincent JL, Svensson L.

JAMA. 2019 May 7;321(17):1677-1685. doi: 10.1001/jama.2019.4149.


[Presumed consent for organ donation? : A survey among members of the German Society of Medical Intensive Care and Emergency Medicine].

Janssens U, Michels G, Karagiannidis C, Riessen R, Busch HJ, Welte T, Werdan K, Buerke M, John S, Kluge S.

Med Klin Intensivmed Notfmed. 2019 Apr 10. doi: 10.1007/s00063-019-0579-2. [Epub ahead of print] German.


ABA-Induced Vegetative Diaspore Formation in Physcomitrella patens.

Arif MA, Hiss M, Tomek M, Busch H, Meyberg R, Tintelnot S, Reski R, Rensing SA, Frank W.

Front Plant Sci. 2019 Mar 19;10:315. doi: 10.3389/fpls.2019.00315. eCollection 2019.


Genome-wide association study of psoriasis in an Egyptian population.

Bejaoui Y, Witte M, Abdelhady M, Eldarouti M, Abdallah NMA, Elghzaly AA, Tawhid Z, Gaballah MA, Busch H, Munz M, Wendorff M, Ellinghaus E, Franke A, Ibrahim SM.

Exp Dermatol. 2019 May;28(5):623-627. doi: 10.1111/exd.13926.


Semaphorin 3F Promotes Transendothelial Migration of Leukocytes in the Inflammatory Response After Survived Cardiac Arrest.

Reichert S, Scheid S, Roth T, Herkel M, Petrova D, Linden A, Weberbauer M, Esser J, Diehl P, Grundmann S, Busch HJ, Fink K, Bode C, Moser M, Helbing T.

Inflammation. 2019 Aug;42(4):1252-1264. doi: 10.1007/s10753-019-00985-4.


[Standardized focused echocardiography in acute medicine].

Michels G, Busch HJ.

Dtsch Med Wochenschr. 2019 Feb;144(4):288. doi: 10.1055/a-0754-9059. Epub 2019 Feb 13. German. No abstract available.


Delineating the Dynamic Transcriptome Response of mRNA and microRNA during Zebrafish Heart Regeneration.

Klett H, Jürgensen L, Most P, Busch M, Günther F, Dobreva G, Leuschner F, Hassel D, Busch H, Boerries M.

Biomolecules. 2018 Dec 28;9(1). pii: E11. doi: 10.3390/biom9010011.


Reminiscing to teach others and prepare for death is associated with meaning in life through generative behavior in elderlies from four cultures.

Hofer J, Busch H, Au A, Poláčková Šolcová I, Tavel P, Tsien Wong T.

Aging Ment Health. 2018 Dec 29:1-9. doi: 10.1080/13607863.2018.1548568. [Epub ahead of print]


Infection of HeLa cells with Chlamydia trachomatis inhibits protein synthesis and causes multiple changes to host cell pathways.

Ohmer M, Tzivelekidis T, Niedenführ N, Volceanov-Hahn L, Barth S, Vier J, Börries M, Busch H, Kook L, Biniossek ML, Schilling O, Kirschnek S, Häcker G.

Cell Microbiol. 2019 Apr;21(4):e12993. doi: 10.1111/cmi.12993. Epub 2019 Jan 7.


MMP14 empowers tumor-initiating breast cancer cells under hypoxic nutrient-depleted conditions.

Hillebrand LE, Wickberg SM, Gomez-Auli A, Follo M, Maurer J, Busch H, Boerries M, Reinheckel T.

FASEB J. 2019 Mar;33(3):4124-4140. doi: 10.1096/fj.201801127R. Epub 2018 Dec 6.


DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation.

Wanner N, Vornweg J, Combes A, Wilson S, Plappert J, Rafflenbeul G, Puelles VG, Rahman RU, Liwinski T, Lindner S, Grahammer F, Kretz O, Wlodek ME, Romano T, Moritz KM, Boerries M, Busch H, Bonn S, Little MH, Bechtel-Walz W, Huber TB.

J Am Soc Nephrol. 2019 Jan;30(1):63-78. doi: 10.1681/ASN.2018070736. Epub 2018 Dec 5.


Dietary ursolic acid improves health span and life span in male Drosophila melanogaster.

Staats S, Wagner AE, Lüersen K, Künstner A, Meyer T, Kahns AK, Derer S, Graspeuntner S, Rupp J, Busch H, Sina C, Ipharraguerre IR, Rimbach G.

Biofactors. 2019 Mar;45(2):169-186. doi: 10.1002/biof.1467. Epub 2018 Nov 29.


Detecting delirium in elderly medical emergency patients: validation and subsequent modification of the German Nursing Delirium Screening Scale.

Brich J, Baten V, Wußmann J, Heupel-Reuter M, Perlov E, Klöppel S, Busch HJ.

Intern Emerg Med. 2019 Aug;14(5):767-776. doi: 10.1007/s11739-018-1989-5. Epub 2018 Nov 27.


Soil Bacteria Isolated From Tunisian Arid Areas Show Promising Antimicrobial Activities Against Gram-Negatives.

Nasfi Z, Busch H, Kehraus S, Linares-Otoya L, König GM, Schäberle TF, Bachoual R.

Front Microbiol. 2018 Nov 13;9:2742. doi: 10.3389/fmicb.2018.02742. eCollection 2018.


Constitutional absence of epithelial integrin α3 impacts the composition of the cellular microenvironment of ILNEB keratinocytes.

He Y, Thriene K, Boerries M, Hausser I, Franzke CW, Busch H, Dengjel J, Has C.

Matrix Biol. 2018 Dec;74:62-76. doi: 10.1016/j.matbio.2018.07.001. Epub 2018 Jul 3.


[Transient loss of consciousness : Algorithm for the (differential) diagnosis of syncope at emergency department].

Sayk F, Frimmel M, Dodt C, Busch HJ, Wolfrum S.

Med Klin Intensivmed Notfmed. 2019 Jun;114(5):410-419. doi: 10.1007/s00063-018-0501-3. Epub 2018 Nov 9. Review. German.


Recommendations for extracorporeal cardiopulmonary resuscitation (eCPR): consensus statement of DGIIN, DGK, DGTHG, DGfK, DGNI, DGAI, DIVI and GRC.

Michels G, Wengenmayer T, Hagl C, Dohmen C, Böttiger BW, Bauersachs J, Markewitz A, Bauer A, Gräsner JT, Pfister R, Ghanem A, Busch HJ, Kreimeier U, Beckmann A, Fischer M, Kill C, Janssens U, Kluge S, Born F, Hoffmeister HM, Preusch M, Boeken U, Riessen R, Thiele H.

Clin Res Cardiol. 2019 May;108(5):455-464. doi: 10.1007/s00392-018-1366-4. Epub 2018 Sep 4. Review.


Macrophage Migration Inhibitory Factor (MIF) Drives Murine Psoriasiform Dermatitis.

Bezdek S, Leng L, Busch H, Mousavi S, Rades D, Dahlke M, Zillikens D, Bucala R, Sadik CD.

Front Immunol. 2018 Oct 2;9:2262. doi: 10.3389/fimmu.2018.02262. eCollection 2018.


Long-term survival of teeth in the posterior region after apical surgery.

Beck-Broichsitter BE, Schmid H, Busch HP, Wiltfang J, Becker ST.

J Craniomaxillofac Surg. 2018 Nov;46(11):1934-1938. doi: 10.1016/j.jcms.2018.08.005. Epub 2018 Aug 21.


IL-17A is functionally relevant and a potential therapeutic target in bullous pemphigoid.

Chakievska L, Holtsche MM, Künstner A, Goletz S, Petersen BS, Thaci D, Ibrahim SM, Ludwig RJ, Franke A, Sadik CD, Zillikens D, Hölscher C, Busch H, Schmidt E.

J Autoimmun. 2019 Jan;96:104-112. doi: 10.1016/j.jaut.2018.09.003. Epub 2018 Sep 13.


Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin.

Haun F, Neumann S, Peintner L, Wieland K, Habicht J, Schwan C, Østevold K, Koczorowska MM, Biniossek M, Kist M, Busch H, Boerries M, Davis RJ, Maurer U, Schilling O, Aktories K, Borner C.

Nat Commun. 2018 Aug 30;9(1):3524. doi: 10.1038/s41467-018-05850-w.


Lithocholic Acid Improves the Survival of Drosophila Melanogaster.

Staats S, Rimbach G, Kuenstner A, Graspeuntner S, Rupp J, Busch H, Sina C, Ipharraguerre IR, Wagner AE.

Mol Nutr Food Res. 2018 Oct;62(20):e1800424. doi: 10.1002/mnfr.201800424. Epub 2018 Sep 3.


[Recommendations for extracorporeal cardiopulmonary resuscitation (eCPR) : Consensus statement of DGIIN, DGK, DGTHG, DGfK, DGNI, DGAI, DIVI and GRC].

Michels G, Wengenmayer T, Hagl C, Dohmen C, Böttiger BW, Bauersachs J, Markewitz A, Bauer A, Gräsner JT, Pfister R, Ghanem A, Busch HJ, Kreimeier U, Beckmann A, Fischer M, Kill C, Janssens U, Kluge S, Born F, Hoffmeister HM, Preusch M, Boeken U, Riessen R, Thiele H.

Anaesthesist. 2018 Aug;67(8):607-616. doi: 10.1007/s00101-018-0473-y. Review. German.


Bid Expression Network Controls Neuronal Cell Fate During Avian Ciliary Ganglion Development.

Koszinowski S, La Padula V, Edlich F, Krieglstein K, Busch H, Boerries M.

Front Physiol. 2018 Jun 29;9:797. doi: 10.3389/fphys.2018.00797. eCollection 2018.


[Recommendations for extracorporeal cardiopulmonary resuscitation (eCPR) : Consensus statement of DGIIN, DGK, DGTHG, DGfK, DGNI, DGAI, DIVI and GRC].

Michels G, Wengenmayer T, Hagl C, Dohmen C, Böttiger BW, Bauersachs J, Markewitz A, Bauer A, Gräsner JT, Pfister R, Ghanem A, Busch HJ, Kreimeier U, Beckmann A, Fischer M, Kill C, Janssens U, Kluge S, Born F, Hoffmeister HM, Preusch M, Boeken U, Riessen R, Thiele H.

Med Klin Intensivmed Notfmed. 2018 Sep;113(6):478-486. doi: 10.1007/s00063-018-0452-8. German.


Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response.

Dvornikov D, Schneider MA, Ohse S, Szczygieł M, Titkova I, Rosenblatt M, Muley T, Warth A, Herth FJ, Dienemann H, Thomas M, Timmer J, Schilling M, Busch H, Boerries M, Meister M, Klingmüller U.

Sci Rep. 2018 Jun 22;8(1):9517. doi: 10.1038/s41598-018-27912-1.


Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney.

Viau A, Bienaimé F, Lukas K, Todkar AP, Knoll M, Yakulov TA, Hofherr A, Kretz O, Helmstädter M, Reichardt W, Braeg S, Aschman T, Merkle A, Pfeifer D, Dumit VI, Gubler MC, Nitschke R, Huber TB, Terzi F, Dengjel J, Grahammer F, Köttgen M, Busch H, Boerries M, Walz G, Triantafyllopoulou A, Kuehn EW.

EMBO J. 2018 Aug 1;37(15). pii: e98615. doi: 10.15252/embj.201798615. Epub 2018 Jun 19.


Desires and intentions for fatherhood: A comparison of childless gay and heterosexual men in Germany.

Kranz D, Busch H, Niepel C.

J Fam Psychol. 2018 Dec;32(8):995-1004. doi: 10.1037/fam0000439. Epub 2018 Jun 14.


A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes.

Rinschen MM, Gödel M, Grahammer F, Zschiedrich S, Helmstädter M, Kretz O, Zarei M, Braun DA, Dittrich S, Pahmeyer C, Schroder P, Teetzen C, Gee H, Daouk G, Pohl M, Kuhn E, Schermer B, Küttner V, Boerries M, Busch H, Schiffer M, Bergmann C, Krüger M, Hildebrandt F, Dengjel J, Benzing T, Huber TB.

Cell Rep. 2018 May 22;23(8):2495-2508. doi: 10.1016/j.celrep.2018.04.059.


Validation of the Brief Confusion Assessment Method for Screening Delirium in Elderly Medical Patients in a German Emergency Department.

Baten V, Busch HJ, Busche C, Schmid B, Heupel-Reuter M, Perlov E, Brich J, Klöppel S.

Acad Emerg Med. 2018 Nov;25(11):1251-1262. doi: 10.1111/acem.13449. Epub 2018 Jun 8.


Generativity affects fear of death through ego integrity in German, Czech, and Cameroonian older adults.

Busch H, Hofer J, Poláčková Šolcová I, Tavel P.

Arch Gerontol Geriatr. 2018 Jul - Aug;77:89-95. doi: 10.1016/j.archger.2018.04.001. Epub 2018 Apr 18.


Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles.

Klett H, Balavarca Y, Toth R, Gigic B, Habermann N, Scherer D, Schrotz-King P, Ulrich A, Schirmacher P, Herpel E, Brenner H, Ulrich CM, Michels KB, Busch H, Boerries M.

Epigenetics. 2018;13(4):386-397. doi: 10.1080/15592294.2018.1460034. Epub 2018 May 3.


Pathogenetic and Clinical Aspects of Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitides.

Lamprecht P, Kerstein A, Klapa S, Schinke S, Karsten CM, Yu X, Ehlers M, Epplen JT, Holl-Ulrich K, Wiech T, Kalies K, Lange T, Laudien M, Laskay T, Gemoll T, Schumacher U, Ullrich S, Busch H, Ibrahim S, Fischer N, Hasselbacher K, Pries R, Petersen F, Weppner G, Manz R, Humrich JY, Nieberding R, Riemekasten G, Müller A.

Front Immunol. 2018 Apr 9;9:680. doi: 10.3389/fimmu.2018.00680. eCollection 2018. Review.


Identification and Validation of a Diagnostic and Prognostic Multi-Gene Biomarker Panel for Pancreatic Ductal Adenocarcinoma.

Klett H, Fuellgraf H, Levit-Zerdoun E, Hussung S, Kowar S, Küsters S, Bronsert P, Werner M, Wittel U, Fritsch R, Busch H, Boerries M.

Front Genet. 2018 Apr 5;9:108. doi: 10.3389/fgene.2018.00108. eCollection 2018.


[Emergency Medicine : What do we need?]

Busch HJ, Schmid B, Michels G, Wolfrum S.

Med Klin Intensivmed Notfmed. 2018 May;113(4):260-266. doi: 10.1007/s00063-018-0437-7. Epub 2018 Apr 18. Review. German.


Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice.

Hirose M, Schilf P, Gupta Y, Zarse K, Künstner A, Fähnrich A, Busch H, Yin J, Wright MN, Ziegler A, Vallier M, Belheouane M, Baines JF, Tautz D, Johann K, Oelkrug R, Mittag J, Lehnert H, Othman A, Jöhren O, Schwaninger M, Prehn C, Adamski J, Shima K, Rupp J, Häsler R, Fuellen G, Köhling R, Ristow M, Ibrahim SM.

Sci Rep. 2018 Apr 12;8(1):5872. doi: 10.1038/s41598-018-24290-6.


Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Mathew NR, Baumgartner F, Braun L, O'Sullivan D, Thomas S, Waterhouse M, Müller TA, Hanke K, Taromi S, Apostolova P, Illert AL, Melchinger W, Duquesne S, Schmitt-Graeff A, Osswald L, Yan KL, Weber A, Tugues S, Spath S, Pfeifer D, Follo M, Claus R, Lübbert M, Rummelt C, Bertz H, Wäsch R, Haag J, Schmidts A, Schultheiss M, Bettinger D, Thimme R, Ullrich E, Tanriver Y, Vuong GL, Arnold R, Hemmati P, Wolf D, Ditschkowski M, Jilg C, Wilhelm K, Leiber C, Gerull S, Halter J, Lengerke C, Pabst T, Schroeder T, Kobbe G, Rösler W, Doostkam S, Meckel S, Stabla K, Metzelder SK, Halbach S, Brummer T, Hu Z, Dengjel J, Hackanson B, Schmid C, Holtick U, Scheid C, Spyridonidis A, Stölzel F, Ordemann R, Müller LP, Sicre-de-Fontbrune F, Ihorst G, Kuball J, Ehlert JE, Feger D, Wagner EM, Cahn JY, Schnell J, Kuchenbauer F, Bunjes D, Chakraverty R, Richardson S, Gill S, Kröger N, Ayuk F, Vago L, Ciceri F, Müller AM, Kondo T, Teshima T, Klaeger S, Kuster B, Kim DDH, Weisdorf D, van der Velden W, Dörfel D, Bethge W, Hilgendorf I, Hochhaus A, Andrieux G, Börries M, Busch H, Magenau J, Reddy P, Labopin M, Antin JH, Henden AS, Hill GR, Kennedy GA, Bar M, Sarma A, McLornan D, Mufti G, Oran B, Rezvani K, Shah O, Negrin RS, Nagler A, Prinz M, Burchert A, Neubauer A, Beelen D, Mackensen A, von Bubnoff N, Herr W, Becher B, Socié G, Caligiuri MA, Ruggiero E, Bonini C, Häcker G, Duyster J, Finke J, Pearce E, Blazar BR, Zeiser R.

Nat Med. 2018 Apr 10;24(4):526. doi: 10.1038/nm0418-526c.


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