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Items: 1 to 50 of 136

1.

Remotely Monitored Therapy and Nitric Oxide Suppression Identifies Non-Adherence in Severe Asthma.

Heaney LG, Busby J, Bradding P, Chaudhuri R, Mansur AH, Niven R, Pavord ID, Lindsay JT, Costello RW; Medical Research Council UK Refractory Asthma Stratification Programme (RASP-UK).

Am J Respir Crit Care Med. 2018 Oct 19. doi: 10.1164/rccm.201806-1182OC. [Epub ahead of print]

PMID:
30339770
2.

Postdiagnostic Calcium Channel Blocker Use and Breast Cancer Mortality: A Population-based Cohort Study.

Busby J, Mills K, Zhang SD, Liberante FG, Cardwell CR.

Epidemiology. 2018 May;29(3):407-413. doi: 10.1097/EDE.0000000000000814.

PMID:
29608546
3.

Model for Identifying Individuals at Risk for Esophageal Adenocarcinoma.

Kunzmann AT, Thrift AP, Cardwell CR, Lagergren J, Xie S, Johnston BT, Anderson LA, Busby J, McMenamin ÚC, Spence AD, Coleman HG.

Clin Gastroenterol Hepatol. 2018 Aug;16(8):1229-1236.e4. doi: 10.1016/j.cgh.2018.03.014. Epub 2018 Mar 17.

PMID:
29559360
4.

Medications that relax the lower oesophageal sphincter and risk of oesophageal cancer: An analysis of two independent population-based databases.

Spence AD, Busby J, Murchie P, Kunzmann AT, McMenamin ÚC, Coleman HG, Johnston BT, O'Rorke MA, Murray LJ, Iversen L, Lee AJ, Cardwell CR.

Int J Cancer. 2018 Jul 1;143(1):22-31. doi: 10.1002/ijc.31293. Epub 2018 Mar 8.

PMID:
29396851
5.

Post-diagnostic calcium channel blocker use and breast cancer mortality: a population-based cohort study.

Busby J, Mills K, Zhang SD, Liberante FG, Cardwell C.

Epidemiology. 2018 Feb 1. doi: 10.1097/EDE.0000000000000814. [Epub ahead of print]

PMID:
29394190
6.

Selective serotonin reuptake inhibitor use and breast cancer survival: a population-based cohort study.

Busby J, Mills K, Zhang SD, Liberante FG, Cardwell CR.

Breast Cancer Res. 2018 Jan 19;20(1):4. doi: 10.1186/s13058-017-0928-0.

7.

A combined connectivity mapping and pharmacoepidemiology approach to identify existing medications with breast cancer causing or preventing properties.

Busby J, Murray L, Mills K, Zhang SD, Liberante F, Cardwell CR.

Pharmacoepidemiol Drug Saf. 2018 Jan;27(1):78-86. doi: 10.1002/pds.4345. Epub 2017 Dec 4.

PMID:
29205633
8.

Low-Dose Aspirin Use Does Not Increase Survival in 2 Independent Population-Based Cohorts of Patients With Esophageal or Gastric Cancer.

Spence AD, Busby J, Johnston BT, Baron JA, Hughes CM, Coleman HG, Cardwell CR.

Gastroenterology. 2018 Mar;154(4):849-860.e1. doi: 10.1053/j.gastro.2017.10.044. Epub 2017 Nov 6.

PMID:
29122547
9.

Angiotensin receptor blocker use and gastro-oesophageal cancer survival: a population-based cohort study.

Busby J, McMenamin Ú, Spence A, Johnston BT, Hughes C, Cardwell CR.

Aliment Pharmacol Ther. 2018 Jan;47(2):279-288. doi: 10.1111/apt.14388. Epub 2017 Nov 3.

PMID:
29105106
10.

How do population, general practice and hospital factors influence ambulatory care sensitive admissions: a cross sectional study.

Busby J, Purdy S, Hollingworth W.

BMC Fam Pract. 2017 May 25;18(1):67. doi: 10.1186/s12875-017-0638-9.

11.

Calculating hospital length of stay using the Hospital Episode Statistics; a comparison of methodologies.

Busby J, Purdy S, Hollingworth W.

BMC Health Serv Res. 2017 May 12;17(1):347. doi: 10.1186/s12913-017-2295-z.

12.

Patient flow within UK emergency departments: a systematic review of the use of computer simulation modelling methods.

Mohiuddin S, Busby J, Savović J, Richards A, Northstone K, Hollingworth W, Donovan JL, Vasilakis C.

BMJ Open. 2017 May 9;7(5):e015007. doi: 10.1136/bmjopen-2016-015007. Review.

13.

The Diagnosis of Urinary Tract Infection in Young Children (DUTY) Study Clinical Rule: Economic Evaluation.

Hollingworth W, Busby J, Butler CC, O'Brien K, Sterne JA, Hood K, Little P, Lawton M, Birnie K, Thomas-Jones E, Harman K, Hay AD; DUTY Study Team.

Value Health. 2017 Apr;20(4):556-566. doi: 10.1016/j.jval.2017.01.003. Epub 2017 Feb 22.

14.

The role of general practice in reducing unplanned hospital admissions.

Busby J, Hollingworth W, Purdy S.

Br J Hosp Med (Lond). 2017 Apr 2;78(4):186-187. doi: 10.12968/hmed.2017.78.4.186. No abstract available.

PMID:
28398883
15.

The effect of medications which cause inflammation of the gastro-oesophageal tract on cancer risk: a nested case-control study of routine Scottish data.

Busby J, Murchie P, Murray L, Iversen L, Lee AJ, Spence A, Watson MC, Cardwell CR.

Int J Cancer. 2017 Apr 15;140(8):1828-1835. doi: 10.1002/ijc.30612. Epub 2017 Feb 6.

16.

Analysis of Affordance, Time, and Adaptation in the Assessment of Industrial Control System Cybersecurity Risk.

Busby JS, Green B, Hutchison D.

Risk Anal. 2017 Jul;37(7):1298-1314. doi: 10.1111/risa.12681. Epub 2017 Jan 17.

PMID:
28095596
17.

An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition.

Egan B, Yuan CC, Craske ML, Labhart P, Guler GD, Arnott D, Maile TM, Busby J, Henry C, Kelly TK, Tindell CA, Jhunjhunwala S, Zhao F, Hatton C, Bryant BM, Classon M, Trojer P.

PLoS One. 2016 Nov 22;11(11):e0166438. doi: 10.1371/journal.pone.0166438. eCollection 2016.

18.

Using geographic variation in unplanned ambulatory care sensitive condition admission rates to identify commissioning priorities: an analysis of routine data from England.

Busby J, Purdy S, Hollingworth W.

J Health Serv Res Policy. 2017 Jan;22(1):20-27. doi: 10.1177/1355819616666397. Epub 2016 Nov 30.

PMID:
27827306
19.

Opportunities for primary care to reduce hospital admissions: a cross-sectional study of geographical variation.

Busby J, Purdy S, Hollingworth W.

Br J Gen Pract. 2017 Jan;67(654):e20-e28. doi: 10.3399/bjgp16X687949. Epub 2016 Oct 24.

20.

The Diagnosis of Urinary Tract infection in Young children (DUTY): a diagnostic prospective observational study to derive and validate a clinical algorithm for the diagnosis of urinary tract infection in children presenting to primary care with an acute illness.

Hay AD, Birnie K, Busby J, Delaney B, Downing H, Dudley J, Durbaba S, Fletcher M, Harman K, Hollingworth W, Hood K, Howe R, Lawton M, Lisles C, Little P, MacGowan A, O'Brien K, Pickles T, Rumsby K, Sterne JA, Thomas-Jones E, van der Voort J, Waldron CA, Whiting P, Wootton M, Butler CC.

Health Technol Assess. 2016 Jul;20(51):1-294. doi: 10.3310/hta20510.

21.

Improving the Diagnosis and Treatment of Urinary Tract Infection in Young Children in Primary Care: Results from the DUTY Prospective Diagnostic Cohort Study.

Hay AD, Sterne JA, Hood K, Little P, Delaney B, Hollingworth W, Wootton M, Howe R, MacGowan A, Lawton M, Busby J, Pickles T, Birnie K, O'Brien K, Waldron CA, Dudley J, Van Der Voort J, Downing H, Thomas-Jones E, Harman K, Lisles C, Rumsby K, Durbaba S, Whiting P, Butler CC.

Ann Fam Med. 2016 Jul;14(4):325-36. doi: 10.1370/afm.1954.

22.

An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells.

Vinogradova M, Gehling VS, Gustafson A, Arora S, Tindell CA, Wilson C, Williamson KE, Guler GD, Gangurde P, Manieri W, Busby J, Flynn EM, Lan F, Kim HJ, Odate S, Cochran AG, Liu Y, Wongchenko M, Yang Y, Cheung TK, Maile TM, Lau T, Costa M, Hegde GV, Jackson E, Pitti R, Arnott D, Bailey C, Bellon S, Cummings RT, Albrecht BK, Harmange JC, Kiefer JR, Trojer P, Classon M.

Nat Chem Biol. 2016 Jul;12(7):531-8. doi: 10.1038/nchembio.2085. Epub 2016 May 23.

PMID:
27214401
23.

Combining cross-crystal averaging and MRSAD to phase a 4354-amino-acid structure.

Busby JN, Lott JS, Panjikar S.

Acta Crystallogr D Struct Biol. 2016 Feb;72(Pt 2):182-91. doi: 10.1107/S2059798315023566. Epub 2016 Jan 22.

PMID:
26894666
24.
25.

Using clinical practice variations as a method for commissioners and clinicians to identify and prioritise opportunities for disinvestment in health care: a cross-sectional study, systematic reviews and qualitative study.

Hollingworth W, Rooshenas L, Busby J, Hine CE, Badrinath P, Whiting PF, Moore THM, Owen-Smith A, Sterne JAC, Jones HE, Beynon C, Donovan JL.

Southampton (UK): NIHR Journals Library; 2015 Apr.

26.

EZH2 inhibitor efficacy in non-Hodgkin's lymphoma does not require suppression of H3K27 monomethylation.

Bradley WD, Arora S, Busby J, Balasubramanian S, Gehling VS, Nasveschuk CG, Vaswani RG, Yuan CC, Hatton C, Zhao F, Williamson KE, Iyer P, Méndez J, Campbell R, Cantone N, Garapaty-Rao S, Audia JE, Cook AS, Dakin LA, Albrecht BK, Harmange JC, Daniels DL, Cummings RT, Bryant BM, Normant E, Trojer P.

Chem Biol. 2014 Nov 20;21(11):1463-75. doi: 10.1016/j.chembiol.2014.09.017.

27.

Can urinary PCA3 supplement PSA in the early detection of prostate cancer?

Wei JT, Feng Z, Partin AW, Brown E, Thompson I, Sokoll L, Chan DW, Lotan Y, Kibel AS, Busby JE, Bidair M, Lin DW, Taneja SS, Viterbo R, Joon AY, Dahlgren J, Kagan J, Srivastava S, Sanda MG.

J Clin Oncol. 2014 Dec 20;32(36):4066-72. doi: 10.1200/JCO.2013.52.8505. Epub 2014 Nov 10.

28.

A mutation in Ampd2 is associated with nephrotic syndrome and hypercholesterolemia in mice.

Helmering J, Juan T, Li CM, Chhoa M, Baron W, Gyuris T, Richards WG, Turk JR, Lawrence J, Cosgrove PA, Busby J, Kim KW, Kaufman SA, Cummings C, Carlson G, Véniant MM, Lloyd DJ.

Lipids Health Dis. 2014 Oct 31;13:167. doi: 10.1186/1476-511X-13-167.

29.

Crystal structure of PhnF, a GntR-family transcriptional regulator of phosphate transport in Mycobacterium smegmatis.

Gebhard S, Busby JN, Fritz G, Moreland NJ, Cook GM, Lott JS, Baker EN, Money VA.

J Bacteriol. 2014 Oct;196(19):3472-81. doi: 10.1128/JB.01965-14. Epub 2014 Jul 21.

30.

Organizational sensemaking about risk controls: the case of offshore hydrocarbons production.

Busby JS, Collins AM.

Risk Anal. 2014 Sep;34(9):1738-52. doi: 10.1111/risa.12198. Epub 2014 Apr 1.

PMID:
24689551
31.

Piperazine oxadiazole inhibitors of acetyl-CoA carboxylase.

Bourbeau MP, Siegmund A, Allen JG, Shu H, Fotsch C, Bartberger MD, Kim KW, Komorowski R, Graham M, Busby J, Wang M, Meyer J, Xu Y, Salyers K, Fielden M, Véniant MM, Gu W.

J Med Chem. 2013 Dec 27;56(24):10132-41. doi: 10.1021/jm401601s. Epub 2013 Dec 11.

PMID:
24294923
32.

Identification of EZH2 and EZH1 small molecule inhibitors with selective impact on diffuse large B cell lymphoma cell growth.

Garapaty-Rao S, Nasveschuk C, Gagnon A, Chan EY, Sandy P, Busby J, Balasubramanian S, Campbell R, Zhao F, Bergeron L, Audia JE, Albrecht BK, Harmange JC, Cummings R, Trojer P.

Chem Biol. 2013 Nov 21;20(11):1329-39. doi: 10.1016/j.chembiol.2013.09.013. Epub 2013 Oct 31.

33.

Direct interaction between AR and PAK6 in androgen-stimulated PAK6 activation.

Liu X, Busby J, John C, Wei J, Yuan X, Lu ML.

PLoS One. 2013 Oct 10;8(10):e77367. doi: 10.1371/journal.pone.0077367. eCollection 2013.

34.

A pragmatic randomised controlled trial of 'PhysioDirect' telephone assessment and advice services for patients with musculoskeletal problems: economic evaluation.

Hollinghurst S, Coast J, Busby J, Bishop A, Foster NE, Franchini A, Grove S, Hall J, Hopper C, Kaur S, Montgomery AA, Salisbury C.

BMJ Open. 2013 Oct 3;3(10):e003406. doi: 10.1136/bmjopen-2013-003406.

35.

The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation device.

Busby JN, Panjikar S, Landsberg MJ, Hurst MR, Lott JS.

Nature. 2013 Sep 26;501(7468):547-50. doi: 10.1038/nature12465. Epub 2013 Aug 4.

PMID:
23913273
36.

Uptake of carotid artery stenting in England and subsequent vascular admissions: an appropriate response to emerging evidence?

Lee AH, Busby J, Brooks M, Hollingworth W.

Eur J Vasc Endovasc Surg. 2013 Sep;46(3):282-9. doi: 10.1016/j.ejvs.2013.04.019. Epub 2013 May 20.

37.

Temporal growth and geographic variation in the use of laboratory tests by NHS general practices: using routine data to identify research priorities.

Busby J, Schroeder K, Woltersdorf W, Sterne JA, Ben-Shlomo Y, Hay A, Hollingworth W.

Br J Gen Pract. 2013 Apr;63(609):e256-66. doi: 10.3399/bjgp13X665224.

38.

Trends in procedures for infertility and caesarean sections: was NICE disinvestment guidance implemented? NICE recommendation reminders.

Chamberlain CA, Martin RM, Busby J, Gilbert R, Cahill DJ, Hollingworth W.

BMC Public Health. 2013 Feb 6;13:112. doi: 10.1186/1471-2458-13-112.

39.

A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of 'PhysioDirect' telephone assessment and advice services for physiotherapy.

Salisbury C, Foster NE, Hopper C, Bishop A, Hollinghurst S, Coast J, Kaur S, Pearson J, Franchini A, Hall J, Grove S, Calnan M, Busby J, Montgomery AA.

Health Technol Assess. 2013 Jan;17(2):1-157, v-vi. doi: 10.3310/hta17020.

40.

Prostate cancer, Version 3.2012: featured updates to the NCCN guidelines.

Mohler JL, Armstrong AJ, Bahnson RR, Boston B, Busby JE, D'Amico AV, Eastham JA, Enke CA, Farrington T, Higano CS, Horwitz EM, Kantoff PW, Kawachi MH, Kuettel M, Lee RJ, MacVicar GR, Malcolm AW, Miller D, Plimack ER, Pow-Sang JM, Roach M 3rd, Rohren E, Rosenfeld S, Srinivas S, Strope SA, Tward J, Twardowski P, Walsh PC, Ho M, Shead DA.

J Natl Compr Canc Netw. 2012 Sep;10(9):1081-7.

PMID:
22956807
41.

FGF21 promotes metabolic homeostasis via white adipose and leptin in mice.

Véniant MM, Hale C, Helmering J, Chen MM, Stanislaus S, Busby J, Vonderfecht S, Xu J, Lloyd DJ.

PLoS One. 2012;7(7):e40164. doi: 10.1371/journal.pone.0040164. Epub 2012 Jul 6.

42.

Robotic versus open radical cystectomy: identification of patients who benefit from the robotic approach.

Knox ML, El-Galley R, Busby JE.

J Endourol. 2013 Jan;27(1):40-4. doi: 10.1089/end.2012.0168. Epub 2012 Oct 11.

PMID:
22788707
43.

A phase 2 cancer chemoprevention biomarker trial of isoflavone G-2535 (genistein) in presurgical bladder cancer patients.

Messing E, Gee JR, Saltzstein DR, Kim K, diSant'Agnese A, Kolesar J, Harris L, Faerber A, Havighurst T, Young JM, Efros M, Getzenberg RH, Wheeler MA, Tangrea J, Parnes H, House M, Busby JE, Hohl R, Bailey H.

Cancer Prev Res (Phila). 2012 Apr;5(4):621-30. doi: 10.1158/1940-6207.CAPR-11-0455. Epub 2012 Jan 31.

44.

3D structure of the Yersinia entomophaga toxin complex and implications for insecticidal activity.

Landsberg MJ, Jones SA, Rothnagel R, Busby JN, Marshall SD, Simpson RM, Lott JS, Hankamer B, Hurst MR.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20544-9. doi: 10.1073/pnas.1111155108. Epub 2011 Dec 7.

45.

Health policy: lost in transition, losing money, but caution precludes a "quick fix".

Demark-Wahnefried W, Busby JE.

Nat Rev Urol. 2011 Dec 13;9(1):14-6. doi: 10.1038/nrurol.2011.205. No abstract available.

46.

Multi-institutional analysis of robotic radical cystectomy for bladder cancer: perioperative outcomes and complications in 227 patients.

Smith AB, Raynor M, Amling CL, Busby JE, Castle E, Davis R, Nielsen M, Thomas R, Wallen EM, Woods M, Pruthi RS.

J Laparoendosc Adv Surg Tech A. 2012 Jan-Feb;22(1):17-21. doi: 10.1089/lap.2011.0326. Epub 2011 Dec 5.

PMID:
22142028
47.

Structural analysis of Chi1 Chitinase from Yen-Tc: the multisubunit insecticidal ABC toxin complex of Yersinia entomophaga.

Busby JN, Landsberg MJ, Simpson RM, Jones SA, Hankamer B, Hurst MR, Lott JS.

J Mol Biol. 2012 Jan 13;415(2):359-71. doi: 10.1016/j.jmb.2011.11.018. Epub 2011 Nov 15.

PMID:
22108167
48.

Outcome of hand assisted laparoscopic bilateral native nephrectomy in transplant recipients.

El-Galley R, Safavy S, Busby JE, Colli J.

J Urol. 2011 Mar;185(3):1021-5. doi: 10.1016/j.juro.2010.10.084. Epub 2011 Jan 19.

PMID:
21251679
49.

Is risk-based regulation feasible? The case of polybrominated diphenyl ethers (PBDEs).

MacGillivray BH, Alcock RE, Busby J.

Risk Anal. 2011 Feb;31(2):266-81. doi: 10.1111/j.1539-6924.2010.01500.x. Epub 2010 Sep 29.

PMID:
20880219
50.

Understanding the mismatch between the demands of risk assessment and practice of scientists--the case of Deca-BDE.

Alcock RE, Macgillivray BH, Busby JS.

Environ Int. 2011 Jan;37(1):216-25. doi: 10.1016/j.envint.2010.06.002. Epub 2010 Jul 6. Review.

PMID:
20609476

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