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Items: 1 to 50 of 105

1.

Response to the comments of Runyan et al. on "Trichloroethylene in drinking water throughout gestation did not produce congenital heart defects in Sprague Dawley rats".

DeSesso JM, Coder PS, York RG, Budinsky RA, Pottenger LH, Sen S, Lucarell JM, Bevan C, Bus JS.

Birth Defects Res. 2019 Oct 1;111(16):1237-1239. doi: 10.1002/bdr2.1577. Epub 2019 Aug 16. No abstract available.

PMID:
31419071
2.

Evaluation of potential health effects associated with occupational and environmental exposure to styrene - an update.

Banton MI, Bus JS, Collins JJ, Delzell E, Gelbke HP, Kester JE, Moore MM, Waites R, Sarang SS.

J Toxicol Environ Health B Crit Rev. 2019;22(1-4):1-130. doi: 10.1080/10937404.2019.1633718. Epub 2019 Jul 8.

PMID:
31284836
3.

Trichloroethylene in drinking water throughout gestation did not produce congenital heart defects in Sprague Dawley rats.

DeSesso JM, Coder PS, York RG, Budinsky RA, Pottenger LH, Sen S, Lucarell JM, Bevan C, Bus JS.

Birth Defects Res. 2019 Oct 1;111(16):1217-1233. doi: 10.1002/bdr2.1531. Epub 2019 Jun 13.

PMID:
31197966
4.

Strain-related differences in mouse lung gene expression over a two-year period of inhalation exposure to styrene: Relevance to human risk assessment.

Andersen ME, Cruzan G, Black MB, Pendse SN, Dodd DE, Bus JS, Sarang SS, Banton MI, Waites R, Layko DB, McMullen PD.

Regul Toxicol Pharmacol. 2018 Jul;96:153-166. doi: 10.1016/j.yrtph.2018.05.011. Epub 2018 May 17.

5.

Based on an analysis of mode of action, styrene-induced mouse lung tumors are not a human cancer concern.

Cruzan G, Bus JS, Andersen ME, Carlson GP, Banton MI, Sarang SS, Waites R.

Regul Toxicol Pharmacol. 2018 Jun;95:17-28. doi: 10.1016/j.yrtph.2018.02.010. Epub 2018 Feb 26.

6.

Editor's Highlight: Complete Attenuation of Mouse Lung Cell Proliferation and Tumorigenicity in CYP2F2 Knockout and CYP2F1 Humanized Mice Exposed to Inhaled Styrene for up to 2 Years Supports a Lack of Human Relevance.

Cruzan G, Bus JS, Banton MI, Sarang SS, Waites R, Layko DB, Raymond J, Dodd D, Andersen ME.

Toxicol Sci. 2017 Oct 1;159(2):413-421. doi: 10.1093/toxsci/kfx141.

7.

Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling following 1-day and multi-week exposures.

Andersen ME, Cruzan G, Black MB, Pendse SN, Dodd D, Bus JS, Sarang SS, Banton MI, Waites R, McMullen PD.

Toxicol Appl Pharmacol. 2017 Nov 15;335:28-40. doi: 10.1016/j.taap.2017.09.015. Epub 2017 Sep 23.

8.

How well can carcinogenicity be predicted by high throughput "characteristics of carcinogens" mechanistic data?

Becker RA, Dreier DA, Manibusan MK, Cox LAT, Simon TW, Bus JS.

Regul Toxicol Pharmacol. 2017 Nov;90:185-196. doi: 10.1016/j.yrtph.2017.08.021. Epub 2017 Sep 1.

9.

Combining transcriptomics and PBPK modeling indicates a primary role of hypoxia and altered circadian signaling in dichloromethane carcinogenicity in mouse lung and liver.

Andersen ME, Black MB, Campbell JL, Pendse SN, Clewell HJ III, Pottenger LH, Bus JS, Dodd DE, Kemp DC, McMullen PD.

Toxicol Appl Pharmacol. 2017 Oct 1;332:149-158. doi: 10.1016/j.taap.2017.04.002. Epub 2017 Apr 7.

10.
12.

Risk assessments for chronic exposure of children and prospective parents to ethylbenzene (CAS No. 100-41-4).

Sweeney LM, Kester JE, Kirman CR, Gentry PR, Banton MI, Bus JS, Gargas ML.

Crit Rev Toxicol. 2015;45(8):662-726. doi: 10.3109/10408444.2015.1046157. Epub 2015 Sep 25. Review.

PMID:
25997510
13.

Human health screening level risk assessments of tertiary-butyl acetate (TBAC): calculated acute and chronic reference concentration (RfC) and Hazard Quotient (HQ) values based on toxicity and exposure scenario evaluations.

Bus JS, Banton MI, Faber WD, Kirman CR, McGregor DB, Pourreau DB.

Crit Rev Toxicol. 2015 Feb;45(2):142-71. doi: 10.3109/10408444.2014.980884. Epub 2015 Jan 28. Review.

PMID:
25629921
14.

Re: Knapp DW, Peer WA, Conteh A, Diggs AR, Cooper BR, Glickman NW, et al. detection of herbicides in the urine of pet dogs following home lawn application. Sci Total Env 2013; 456-457: 34-41.

Bus JS, Hammond L.

Sci Total Environ. 2014 Jul 15;487:576-7. doi: 10.1016/j.scitotenv.2014.03.081. Epub 2014 Apr 13. No abstract available.

PMID:
24739893
15.

Assessment of the genotoxicity of trichloroethylene in the in vivo micronucleus assay by inhalation exposure.

Wilmer JW, Spencer PJ, Ball N, Bus JS.

Mutagenesis. 2014 May;29(3):209-14. doi: 10.1093/mutage/geu006. Epub 2014 Mar 11.

PMID:
24618993
16.

Nonmalignant respiratory disease mortality in styrene-exposed workers.

Collins JJ, Bodner KM, Bus JS.

Epidemiology. 2014 Jan;25(1):161-2. doi: 10.1097/EDE.0b013e3182a798fa. No abstract available.

PMID:
24296937
17.

FutureTox: building the road for 21st century toxicology and risk assessment practices.

Rowlands JC, Sander M, Bus JS; FutureTox Organizing Committee.

Toxicol Sci. 2014 Feb;137(2):269-77. doi: 10.1093/toxsci/kft252. Epub 2013 Nov 7.

18.

Life-stage-, sex-, and dose-dependent dietary toxicokinetics and relationship to toxicity of 2,4-dichlorophenoxyacetic acid (2,4-D) in rats: implications for toxicity test dose selection, design, and interpretation.

Saghir SA, Marty MS, Zablotny CL, Passage JK, Perala AW, Neal BH, Hammond L, Bus JS.

Toxicol Sci. 2013 Dec;136(2):294-307. doi: 10.1093/toxsci/kft212. Epub 2013 Oct 8.

19.

An F1-extended one-generation reproductive toxicity study in Crl:CD(SD) rats with 2,4-dichlorophenoxyacetic acid.

Marty MS, Neal BH, Zablotny CL, Yano BL, Andrus AK, Woolhiser MR, Boverhof DR, Saghir SA, Perala AW, Passage JK, Lawson MA, Bus JS, Lamb JC 4th, Hammond L.

Toxicol Sci. 2013 Dec;136(2):527-47. doi: 10.1093/toxsci/kft213. Epub 2013 Sep 26.

20.

A framework for fit-for-purpose dose response assessment.

Bette Meek ME, Bolger M, Bus JS, Christopher J, Conolly RB, Lewis RJ, Paolini GM, Schoeny R, Haber LT, Rosenstein AB, Dourson ML.

Regul Toxicol Pharmacol. 2013 Jul;66(2):234-40. doi: 10.1016/j.yrtph.2013.03.012. Epub 2013 Apr 6.

21.

Cancer mortality of workers exposed to styrene in the U.S. Reinforced plastics and composite industry.

Collins JJ, Bodner KM, Bus JS.

Epidemiology. 2013 Mar;24(2):195-203. doi: 10.1097/EDE.0b013e318281a30f.

PMID:
23344212
22.

Assessment of diurnal systemic dose of agrochemicals in regulatory toxicity testing--an integrated approach without additional animal use.

Saghir SA, Bartels MJ, Rick DL, McCoy AT, Rasoulpour RJ, Ellis-Hutchings RG, Sue Marty M, Terry C, Bailey JP, Billington R, Bus JS.

Regul Toxicol Pharmacol. 2012 Jul;63(2):321-32. doi: 10.1016/j.yrtph.2012.03.004. Epub 2012 Mar 14.

PMID:
22440553
23.

Use of toxicokinetics to support chemical evaluation: Informing high dose selection and study interpretation.

Creton S, Saghir SA, Bartels MJ, Billington R, Bus JS, Davies W, Dent MP, Hawksworth GM, Parry S, Travis KZ.

Regul Toxicol Pharmacol. 2012 Mar;62(2):241-7. doi: 10.1016/j.yrtph.2011.12.005. Epub 2011 Dec 16.

PMID:
22198561
24.

Letter to the editor regarding the article by Paganelli et Al.

Saltmiras D, Bus JS, Spanogle T, Hauswirth J, Tobia A, Hill S.

Chem Res Toxicol. 2011 May 16;24(5):607-8. doi: 10.1021/tx100452k. Epub 2011 Mar 21. No abstract available.

PMID:
21417442
25.

Oral gavage subchronic neurotoxicity and inhalation subchronic immunotoxicity studies of ethylbenzene in the rat.

Li AA, Maurissen JP, Barnett JF Jr, Foss J, Freshwater L, Garman RH, Peachee VL, Hong SJ, Stump DG, Bus JS.

Neurotoxicology. 2010 Jun;31(3):247-58. doi: 10.1016/j.neuro.2010.02.001. Epub 2010 Feb 19. Review.

PMID:
20171981
26.

In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis.

Saghir SA, Zhang F, Rick DL, Kan L, Bus JS, Bartels MJ.

Regul Toxicol Pharmacol. 2010 Jul-Aug;57(2-3):129-35. doi: 10.1016/j.yrtph.2010.01.003. Epub 2010 Jan 22.

PMID:
20096743
27.

Toxicity testing in the 21st century: a view from the chemical industry.

Bus JS, Becker RA.

Toxicol Sci. 2009 Dec;112(2):297-302. doi: 10.1093/toxsci/kfp234. Epub 2009 Oct 4. No abstract available.

PMID:
19805406
28.

Twenty-first century approaches to toxicity testing, biomonitoring, and risk assessment: perspectives from the global chemical industry.

Phillips RD, Bahadori T, Barry BE, Bus JS, Gant TW, Mostowy JM, Smith C, Willuhn M, Zimmer U.

J Expo Sci Environ Epidemiol. 2009 Sep;19(6):536-43. doi: 10.1038/jes.2009.38.

PMID:
19690554
29.

Mechanism of ethylbenzene-induced mouse-specific lung tumor: metabolism of ethylbenzene by rat, mouse, and human liver and lung microsomes.

Saghir SA, Rick DL, McClymont EL, Zhang F, Bartels MJ, Bus JS.

Toxicol Sci. 2009 Feb;107(2):352-66. doi: 10.1093/toxsci/kfn244. Epub 2008 Dec 15.

PMID:
19075040
30.

Physiologically based pharmacokinetic modeling of chloroethane disposition in mice, rats, and women.

Gargas ML, Sweeney LM, Himmelstein MW, Pottenger LH, Bus JS, Holder JW.

Toxicol Sci. 2008 Jul;104(1):54-66. doi: 10.1093/toxsci/kfn064. Epub 2008 Apr 2.

PMID:
18385209
31.

The naphthalene state of the science symposium: objectives, organization, structure, and charge.

Belzer RB, Bus JS, Cavalieri EL, Lewis SC, North DW, Pleus RC.

Regul Toxicol Pharmacol. 2008 Jul;51(2 Suppl):S1-5. doi: 10.1016/j.yrtph.2007.10.017. Epub 2007 Nov 21.

PMID:
18243454
32.

Making sense of human biomonitoring data: findings and recommendations of a workshop.

Bahadori T, Phillips RD, Money CD, Quackenboss JJ, Clewell HJ, Bus JS, Robison SH, Humphris CJ, Parekh AA, Osborn K, Kauffman RM.

J Expo Sci Environ Epidemiol. 2007 Jul;17(4):308-13. Epub 2007 May 9.

PMID:
17495868
33.

Improving the scientific foundation for mixtures joint toxicity and risk assessment: contributions from the SOT mixtures project--introduction.

Mason AM, Borgert CJ, Bus JS, Moiz Mumtaz M, Simmons JE, Sipes IG; SOT Mixtures Task Force.

Toxicol Appl Pharmacol. 2007 Sep 1;223(2):99-103. Epub 2007 Feb 24. Review.

PMID:
17434550
35.

Toxicity testing in chemical safety evaluation.

Bus JS.

Curr Protoc Toxicol. 2007 Feb;Chapter 19:Unit19.2. doi: 10.1002/0471141755.tx1902s31.

PMID:
23045142
36.

Strategies to assess systemic exposure of chemicals in subchronic/chronic diet and drinking water studies.

Saghir SA, Mendrala AL, Bartels MJ, Day SJ, Hansen SC, Sushynski JM, Bus JS.

Toxicol Appl Pharmacol. 2006 Mar 15;211(3):245-60. Epub 2005 Jul 22.

PMID:
16040073
37.

Dose-dependent transitions in mechanisms of toxicity: case studies.

Slikker W Jr, Andersen ME, Bogdanffy MS, Bus JS, Cohen SD, Conolly RB, David RM, Doerrer NG, Dorman DC, Gaylor DW, Hattis D, Rogers JM, Setzer RW, Swenberg JA, Wallace K.

Toxicol Appl Pharmacol. 2004 Dec 15;201(3):226-94. Review.

PMID:
15582646
38.

Dose-dependent transitions in mechanisms of toxicity.

Slikker W Jr, Andersen ME, Bogdanffy MS, Bus JS, Cohen SD, Conolly RB, David RM, Doerrer NG, Dorman DC, Gaylor DW, Hattis D, Rogers JM, Setzer RW, Swenberg JA, Wallace K.

Toxicol Appl Pharmacol. 2004 Dec 15;201(3):203-25. Review.

PMID:
15582645
39.

Herbicide effects on embryo implantation and litter size.

Lamb JC, Neal BH, Ginevan ME, Bus JS, Mahlburg WM.

Environ Health Perspect. 2003 Jul;111(9):A450. No abstract available.

40.

Developmental toxicity studies in rats and rabbits on 2,4-dichlorophenoxyacetic acid and its forms.

Charles JM, Hanley TR Jr, Wilson RD, van Ravenzwaay B, Bus JS.

Toxicol Sci. 2001 Mar;60(1):121-31.

PMID:
11222879
41.

Toxicology: judge data or dollars?

Crissman JW, Bus JS, Miller RR.

Environ Health Perspect. 1999 Oct;107(10):A489-91. No abstract available.

42.

In vivo micronucleus assays on 2,4-dichlorophenoxyacetic acid and its derivatives.

Charles JM, Cunny HC, Wilson RD, Ivett JL, Murli H, Bus JS, Gollapudi B.

Mutat Res. 1999 Jul 21;444(1):227-34.

PMID:
10477358
43.

Evaluation of the genotoxicity of 2,4-dichlorophenoxyacetic acid and its derivatives in mammalian cell cultures.

Gollapudi BB, Charles JM, Linscombe VA, Day SJ, Bus JS.

Mutat Res. 1999 Jul 21;444(1):217-25.

PMID:
10477357
44.

Ames assays and unscheduled DNA synthesis assays on 2, 4-dichlorophenoxyacetic acid and its derivatives.

Charles JM, Cunny HC, Wilson RD, Bus JS, Lawlor TE, Cifone MA, Fellows M, Gollapudi B.

Mutat Res. 1999 Jul 21;444(1):207-16.

PMID:
10477356
45.

Mode of action considerations in the use of transgenic animals for mutagenicity and carcinogenicity evaluations.

Gollapudi BB, Stott WT, Yano BL, Bus JS.

Toxicol Lett. 1998 Dec 28;102-103:479-84.

PMID:
10022299
46.

Single-dose and chronic dietary neurotoxicity screening studies on 2,4-dichlorophenoxyacetic acid in rats.

Mattsson JL, Charles JM, Yano BL, Cunny HC, Wilson RD, Bus JS.

Fundam Appl Toxicol. 1997 Nov;40(1):111-9.

PMID:
9398493
47.

Chronic dietary toxicity/oncogenicity studies on 2,4-dichlorophenoxyacetic acid in rodents.

Charles JM, Bond DM, Jeffries TK, Yano BL, Stott WT, Johnson KA, Cunny HC, Wilson RD, Bus JS.

Fundam Appl Toxicol. 1996 Oct;33(2):166-72.

PMID:
8921335
48.

Comparative subchronic studies on 2,4-dichlorophenoxyacetic acid, amine, and ester in rats.

Charles JM, Cunny HC, Wilson RD, Bus JS.

Fundam Appl Toxicol. 1996 Oct;33(2):161-5.

PMID:
8921334
49.

Comparative subchronic and chronic dietary toxicity studies on 2,4-dichlorophenoxyacetic acid, amine, and ester in the dog.

Charles JM, Dalgard DW, Cunny HC, Wilson RD, Bus JS.

Fundam Appl Toxicol. 1996 Jan;29(1):78-85.

PMID:
8838642
50.

Studies on the renal transport of trimethylpentanoic acid metabolites of 2,2,4-trimethylpentane in rat renal cortical slices.

Lock EA, Strasser J Jr, Bus JS, Charbonneau M.

J Appl Toxicol. 1993 Jul-Aug;13(4):291-6.

PMID:
8376730

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