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Items: 43

1.

Comprehensive single cell mRNA profiling reveals a detailed roadmap for pancreatic endocrinogenesis.

Bastidas-Ponce A, Tritschler S, Dony L, Scheibner K, Tarquis-Medina M, Salinno C, Schirge S, Burtscher I, Böttcher A, Theis FJ, Lickert H, Bakhti M.

Development. 2019 Jun 17;146(12). pii: dev173849. doi: 10.1242/dev.173849.

PMID:
31160421
2.

Point mutations in the PDX1 transactivation domain impair human β-cell development and function.

Wang X, Sterr M, Ansarullah, Burtscher I, Böttcher A, Beckenbauer J, Siehler J, Meitinger T, Häring HU, Staiger H, Cernilogar FM, Schotta G, Irmler M, Beckers J, Wright CVE, Bakhti M, Lickert H.

Mol Metab. 2019 Jun;24:80-97. doi: 10.1016/j.molmet.2019.03.006. Epub 2019 Mar 20.

3.

Mob2 Insufficiency Disrupts Neuronal Migration in the Developing Cortex.

O'Neill AC, Kyrousi C, Einsiedler M, Burtscher I, Drukker M, Markie DM, Kirk EP, Götz M, Robertson SP, Cappello S.

Front Cell Neurosci. 2018 Mar 12;12:57. doi: 10.3389/fncel.2018.00057. eCollection 2018.

4.

Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.

Wang X, Sterr M, Burtscher I, Chen S, Hieronimus A, Machicao F, Staiger H, Häring HU, Lederer G, Meitinger T, Cernilogar FM, Schotta G, Irmler M, Beckers J, Hrabě de Angelis M, Ray M, Wright CVE, Bakhti M, Lickert H.

Mol Metab. 2018 Mar;9:57-68. doi: 10.1016/j.molmet.2018.01.011. Epub 2018 Jan 31.

5.

A novel Cre-inducible knock-in ARL13B-tRFP fusion cilium reporter.

Schmitz F, Burtscher I, Stauber M, Gossler A, Lickert H.

Genesis. 2017 Nov;55(11). doi: 10.1002/dvg.23073. Epub 2017 Oct 13.

PMID:
28948682
6.

Foxa2 and Pdx1 cooperatively regulate postnatal maturation of pancreatic β-cells.

Bastidas-Ponce A, Roscioni SS, Burtscher I, Bader E, Sterr M, Bakhti M, Lickert H.

Mol Metab. 2017 Mar 25;6(6):524-534. doi: 10.1016/j.molmet.2017.03.007. eCollection 2017 Jun.

7.

Foxa2 identifies a cardiac progenitor population with ventricular differentiation potential.

Bardot E, Calderon D, Santoriello F, Han S, Cheung K, Jadhav B, Burtscher I, Artap S, Jain R, Epstein J, Lickert H, Gouon-Evans V, Sharp AJ, Dubois NC.

Nat Commun. 2017 Feb 14;8:14428. doi: 10.1038/ncomms14428.

8.

Generation of a human induced pluripotent stem cell (iPSC) line from a patient with family history of diabetes carrying a C18R mutation in the PDX1 gene.

Wang X, Chen S, Burtscher I, Sterr M, Hieronimus A, Machicao F, Staiger H, Häring HU, Lederer G, Meitinger T, Lickert H.

Stem Cell Res. 2016 Sep;17(2):292-295. doi: 10.1016/j.scr.2016.08.005. Epub 2016 Aug 6.

9.

Generation of a human induced pluripotent stem cell (iPSC) line from a patient carrying a P33T mutation in the PDX1 gene.

Wang X, Chen S, Burtscher I, Sterr M, Hieronimus A, Machicao F, Staiger H, Häring HU, Lederer G, Meitinger T, Lickert H.

Stem Cell Res. 2016 Sep;17(2):273-276. doi: 10.1016/j.scr.2016.08.004. Epub 2016 Aug 5.

10.

Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios.

Hoppe PS, Schwarzfischer M, Loeffler D, Kokkaliaris KD, Hilsenbeck O, Moritz N, Endele M, Filipczyk A, Gambardella A, Ahmed N, Etzrodt M, Coutu DL, Rieger MA, Marr C, Strasser MK, Schauberger B, Burtscher I, Ermakova O, Bürger A, Lickert H, Nerlov C, Theis FJ, Schroeder T.

Nature. 2016 Jul 14;535(7611):299-302. doi: 10.1038/nature18320.

PMID:
27411635
11.

Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation.

Jung B, Padula D, Burtscher I, Landerer C, Lutter D, Theis F, Messias AC, Geerlof A, Sattler M, Kremmer E, Boldt K, Ueffing M, Lickert H.

PLoS One. 2016 Feb 22;11(2):e0149477. doi: 10.1371/journal.pone.0149477. eCollection 2016.

12.

The global gene expression profile of the secondary transition during pancreatic development.

Willmann SJ, Mueller NS, Engert S, Sterr M, Burtscher I, Raducanu A, Irmler M, Beckers J, Sass S, Theis FJ, Lickert H.

Mech Dev. 2016 Feb;139:51-64. doi: 10.1016/j.mod.2015.11.004. Epub 2015 Nov 28.

13.

Homology arms of targeting vectors for gene insertions and CRISPR/Cas9 technology: size does not matter; quality control of targeted clones does.

Petrezselyova S, Kinsky S, Truban D, Sedlacek R, Burtscher I, Lickert H.

Cell Mol Biol Lett. 2015 Dec;20(5):773-87. doi: 10.1515/cmble-2015-0047.

PMID:
26540224
14.

Flattop regulates basal body docking and positioning in mono- and multiciliated cells.

Gegg M, Böttcher A, Burtscher I, Hasenoeder S, Van Campenhout C, Aichler M, Walch A, Grant SG, Lickert H.

Elife. 2014 Oct 8;3. doi: 10.7554/eLife.03842.

15.

miR-335 promotes mesendodermal lineage segregation and shapes a transcription factor gradient in the endoderm.

Yang D, Lutter D, Burtscher I, Uetzmann L, Theis FJ, Lickert H.

Development. 2014 Feb;141(3):514-25. doi: 10.1242/dev.104232.

16.

The Sox17CreERT2 knock-in mouse line displays spatiotemporal activation of Cre recombinase in distinct Sox17 lineage progenitors.

Engert S, Burtscher I, Kalali B, Gerhard M, Lickert H.

Genesis. 2013 Nov;51(11):793-802. doi: 10.1002/dvg.22714. Epub 2013 Oct 1.

PMID:
24038996
17.

Wnt/β-catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse.

Engert S, Burtscher I, Liao WP, Dulev S, Schotta G, Lickert H.

Development. 2013 Aug;140(15):3128-38. doi: 10.1242/dev.088765. Epub 2013 Jul 3.

18.

Foxa2-venus fusion reporter mouse line allows live-cell analysis of endoderm-derived organ formation.

Burtscher I, Barkey W, Lickert H.

Genesis. 2013 Aug;51(8):596-604. doi: 10.1002/dvg.22404. Epub 2013 Jun 26.

PMID:
23712942
19.

Fltp(T2AiCre): a new knock-in mouse line for conditional gene targeting in distinct mono- and multiciliated tissues.

Lange A, Gegg M, Burtscher I, Bengel D, Kremmer E, Lickert H.

Differentiation. 2012 Feb;83(2):S105-13. doi: 10.1016/j.diff.2011.11.003. Epub 2011 Dec 6.

PMID:
22153975
20.

The Sox17-mCherry fusion mouse line allows visualization of endoderm and vascular endothelial development.

Burtscher I, Barkey W, Schwarzfischer M, Theis FJ, Lickert H.

Genesis. 2012 Jun;50(6):496-505. doi: 10.1002/dvg.20829. Epub 2011 Dec 27.

PMID:
22121118
21.

Pitchfork regulates primary cilia disassembly and left-right asymmetry.

Kinzel D, Boldt K, Davis EE, Burtscher I, Trümbach D, Diplas B, Attié-Bitach T, Wurst W, Katsanis N, Ueffing M, Lickert H.

Dev Cell. 2010 Jul 20;19(1):66-77. doi: 10.1016/j.devcel.2010.06.005.

22.

Sox17-2A-iCre: a knock-in mouse line expressing Cre recombinase in endoderm and vascular endothelial cells.

Engert S, Liao WP, Burtscher I, Lickert H.

Genesis. 2009 Sep;47(9):603-10. doi: 10.1002/dvg.20540.

PMID:
19548312
23.

Generation of a mouse line expressing Sox17-driven Cre recombinase with specific activity in arteries.

Liao WP, Uetzmann L, Burtscher I, Lickert H.

Genesis. 2009 Jul;47(7):476-83. doi: 10.1002/dvg.20520.

PMID:
19415628
24.

Foxa2 regulates polarity and epithelialization in the endoderm germ layer of the mouse embryo.

Burtscher I, Lickert H.

Development. 2009 Mar;136(6):1029-38. doi: 10.1242/dev.028415.

25.

Genetic ablation of FLRT3 reveals a novel morphogenetic function for the anterior visceral endoderm in suppressing mesoderm differentiation.

Egea J, Erlacher C, Montanez E, Burtscher I, Yamagishi S, Hess M, Hampel F, Sanchez R, Rodriguez-Manzaneque MT, Bösl MR, Fässler R, Lickert H, Klein R.

Genes Dev. 2008 Dec 1;22(23):3349-62. doi: 10.1101/gad.486708.

26.

A mouse line expressing Foxa2-driven Cre recombinase in node, notochord, floorplate, and endoderm.

Uetzmann L, Burtscher I, Lickert H.

Genesis. 2008 Oct;46(10):515-22. doi: 10.1002/dvg.20410.

PMID:
18798232
27.

Osteonecrosis of the metacarpal head in a patient with a prothrombin 20210A gene mutation.

Björkman A, Jörgsholm P, Burtscher IM.

Scand J Plast Reconstr Surg Hand Surg. 2005;39(6):379-81.

PMID:
16298813
28.

Factor V Leiden and the prothrombin 20210A gene mutation and osteonecrosis of the knee.

Björkman A, Burtscher IM, Svensson PJ, Hillarp A, Besjakov J, Benoni G.

Arch Orthop Trauma Surg. 2005 Feb;125(1):51-5. Epub 2004 Nov 18.

PMID:
15723247
29.

Factor V leiden and prothrombin gene mutation: risk factors for osteonecrosis of the femoral head in adults.

Björkman A, Svensson PJ, Hillarp A, Burtscher IM, Rünow A, Benoni G.

Clin Orthop Relat Res. 2004 Aug;(425):168-72.

PMID:
15292803
30.

Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder.

Groet J, McElwaine S, Spinelli M, Rinaldi A, Burtscher I, Mulligan C, Mensah A, Cavani S, Dagna-Bricarelli F, Basso G, Cotter FE, Nizetic D.

Lancet. 2003 May 10;361(9369):1617-20.

PMID:
12747884
31.

The IGF/IGF-1 receptor signaling pathway as a potential target for cancer therapy.

Burtscher I, Christofori G.

Drug Resist Updat. 1999 Feb;2(1):3-8.

PMID:
11504463
32.

Proton magnetic resonance spectroscopy in brain tumours: clinical applications.

Burtscher IM, Holtås S.

Neuroradiology. 2001 May;43(5):345-52. Review.

PMID:
11396737
33.

Proton MR spectroscopy in clinical routine.

Burtscher IM, Holtås S.

J Magn Reson Imaging. 2001 Apr;13(4):560-7. Review.

PMID:
11276100
34.

A ring-enhancing metastasis with central high signal on diffusion-weighted imaging and low apparent diffusion coefficients.

Holtås S, Geijer B, Strömblad LG, Maly-Sundgren P, Burtscher IM.

Neuroradiology. 2000 Nov;42(11):824-7.

PMID:
11151689
35.

201Thallium SPECT and 1H-MRS compared with MRI in chemotherapy monitoring of high-grade malignant astrocytomas.

Kallén K, Burtscher IM, Holtås S, Ryding E, Rosén I.

J Neurooncol. 2000;46(2):173-85.

PMID:
10894370
36.

Organ damage in treated middle-aged hypertensives compared to normotensives: results from a cross-sectional study in general practice.

Enström I, Burtscher IM, Eskilsson J, Holm K, Holtås S, Pennert K, Thulin T.

Blood Press. 2000;9(1):28-33.

PMID:
10854005
37.

Proton MR spectroscopy and preoperative diagnostic accuracy: an evaluation of intracranial mass lesions characterized by stereotactic biopsy findings.

Burtscher IM, Skagerberg G, Geijer B, Englund E, Ståhlberg F, Holtås S.

AJNR Am J Neuroradiol. 2000 Jan;21(1):84-93.

38.

MRI and proton spectroscopy in a child with Rasmussen's encephalitis. Case report.

Sundgren PC, Burtscher IM, Lundgren J, Geijer B, Holtås S.

Neuroradiology. 1999 Dec;41(12):935-40.

PMID:
10639671
39.

Quality assessment of localization technique performance in small volume in vivo 1H MR spectroscopy.

Burtscher IM, Johansson E, Holtås S, Ståhlberg F.

Magn Reson Imaging. 1999 Dec;17(10):1511-9.

PMID:
10610000
40.
41.

In vivo proton MR spectroscopy of untreated and treated brain abscesses.

Burtscher IM, Holtås S.

AJNR Am J Neuroradiol. 1999 Jun-Jul;20(6):1049-53.

42.

Aneurysm clip MR artifacts. Titanium versus stainless steel and influence of imaging parameters.

Burtscher IM, Owman T, Romner B, Ståhlberg F, Holtås S.

Acta Radiol. 1998 Jan;39(1):70-6.

PMID:
9498874
43.

Proton (1H) MR spectroscopy for routine diagnostic evaluation of brain lesions.

Burtscher IM, Ståhlberg F, Holtås S.

Acta Radiol. 1997 Nov;38(6):953-60.

PMID:
9394648

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