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Items: 41

1.

Quantitative and Mechanistic Assessment of Model Lipophilic Drugs in Micellar Solutions in the Transport Kinetics Across MDR1-MDCK Cell Monolayers.

Ho NFH, Nielsen J, Peterson M, Burton PS.

J Pharm Sci. 2016 Feb;105(2):904-914. doi: 10.1016/j.xphs.2015.11.028.

PMID:
26869435
2.

Solubility and permeability measurement and applications in drug discovery.

Burton PS, Goodwin JT.

Comb Chem High Throughput Screen. 2010 Feb;13(2):101-11. Review.

PMID:
20053165
3.

Evaluation of a basic physiologically based pharmacokinetic model for simulating the first-time-in-animal study.

Germani M, Crivori P, Rocchetti M, Burton PS, Wilson AG, Smith ME, Poggesi I.

Eur J Pharm Sci. 2007 Jul;31(3-4):190-201. Epub 2007 Mar 24.

PMID:
17481865
4.

Poverty and the extent of child obesity in Canada, Norway and the United States.

Phipps SA, Burton PS, Osberg LS, Lethbridge LN.

Obes Rev. 2006 Feb;7(1):5-12. Review.

PMID:
16436098
5.

Evaluation of a physiologically-based pharmacokinetic approach for simulating the first-time-in-animal study.

Germani M, Crivori P, Rocchetti M, Burton PS, Wilson AG, Smith ME, Poggesi I.

Basic Clin Pharmacol Toxicol. 2005 Mar;96(3):254-6. No abstract available.

6.

Influence of molecular flexibility and polar surface area metrics on oral bioavailability in the rat.

Lu JJ, Crimin K, Goodwin JT, Crivori P, Orrenius C, Xing L, Tandler PJ, Vidmar TJ, Amore BM, Wilson AG, Stouten PF, Burton PS.

J Med Chem. 2004 Nov 18;47(24):6104-7.

PMID:
15537364
7.

Summary workshop report: biopharmaceutics classification system--implementation challenges and extension opportunities.

Polli JE, Yu LX, Cook JA, Amidon GL, Borchardt RT, Burnside BA, Burton PS, Chen ML, Conner DP, Faustino PJ, Hawi AA, Hussain AS, Joshi HN, Kwei G, Lee VH, Lesko LJ, Lipper RA, Loper AE, Nerurkar SG, Polli JW, Sanvordeker DR, Taneja R, Uppoor RS, Vattikonda CS, Wilding I, Zhang G.

J Pharm Sci. 2004 Jun;93(6):1375-81. No abstract available.

PMID:
15124197
8.

Predicting oral absorption of drugs: a case study with a novel class of antimicrobial agents.

Hilgers AR, Smith DP, Biermacher JJ, Day JS, Jensen JL, Sims SM, Adams WJ, Friis JM, Palandra J, Hosley JD, Shobe EM, Burton PS.

Pharm Res. 2003 Aug;20(8):1149-55.

PMID:
12948011
9.

Automated analysis of polyethylene glycol-induced inhibition of P-glycoprotein activity in vitro.

Hugger ED, Cole CJ, Raub TJ, Burton PS, Borchardt RT.

J Pharm Sci. 2003 Jan;92(1):21-6.

PMID:
12486678
10.

Predicting drug absorption: how nature made it a difficult problem.

Burton PS, Goodwin JT, Vidmar TJ, Amore BM.

J Pharmacol Exp Ther. 2002 Dec;303(3):889-95. Review.

PMID:
12438506
11.

A comparison of commonly used polyethoxylated pharmaceutical excipients on their ability to inhibit P-glycoprotein activity in vitro.

Hugger ED, Novak BL, Burton PS, Audus KL, Borchardt RT.

J Pharm Sci. 2002 Sep;91(9):1991-2002.

PMID:
12210046
12.

Physicochemical determinants of passive membrane permeability: role of solute hydrogen-bonding potential and volume.

Goodwin JT, Conradi RA, Ho NF, Burton PS.

J Med Chem. 2001 Oct 25;44(22):3721-9. Erratum in: J Med Chem 2002 May 9;45(10):2122.

PMID:
11606137
13.

Activation of apoptotic and inflammatory pathways in dysfunctional donor hearts.

Birks EJ, Yacoub MH, Burton PS, Owen V, Pomerance A, O'Halloran A, Banner NR, Khaghani A, Latif N.

Transplantation. 2000 Nov 27;70(10):1498-506.

PMID:
11118097
14.

An NMR study of conformations of substituted dipeptides in dodecylphosphocholine micelles: implications for drug transport.

Kloosterman DA, Goodwin JT, Burton PS, Conradi RA, Stockman BJ, Scahill TA, Blinn JR.

Biopolymers. 2000 Apr 15;53(5):396-410.

PMID:
10738201
15.

Transport of model peptides across Ascaris suum cuticle.

Sheehy BA, Ho NF, Burton PS, Day JS, Geary TG, Thompson DP.

Mol Biochem Parasitol. 2000 Jan 5;105(1):39-49.

PMID:
10613697
16.

Mechanism, structure-activity studies, and potential applications of glutathione S-transferase-catalyzed cleavage of sulfonamides.

Zhao Z, Koeplinger KA, Peterson T, Conradi RA, Burton PS, Suarato A, Heinrikson RL, Tomasselli AG.

Drug Metab Dispos. 1999 Sep;27(9):992-8.

PMID:
10460797
17.

Strategies toward predicting peptide cellular permeability from computed molecular descriptors.

Goodwin JT, Mao B, Vidmar TJ, Conradi RA, Burton PS.

J Pept Res. 1999 Apr;53(4):355-69.

PMID:
10406214
18.

Properties of native and in vitro glycosylated forms of the glucagon-like peptide-1 receptor antagonist exendin(9-39).

Meurer JA, Colca JR, Burton PS, Elhammer AP.

Metabolism. 1999 Jun;48(6):716-24.

PMID:
10381145
19.

Piperazinyl oxazolidinone antibacterial agents containing a pyridine, diazene, or triazene heteroaromatic ring.

Tucker JA, Allwine DA, Grega KC, Barbachyn MR, Klock JL, Adamski JL, Brickner SJ, Hutchinson DK, Ford CW, Zurenko GE, Conradi RA, Burton PS, Jensen RM.

J Med Chem. 1998 Sep 10;41(19):3727-35.

PMID:
9733498
20.

Generalized essential telangiectasia in the presence of gastrointestinal bleeding.

Checketts SR, Burton PS, Bjorkman DJ, Kadunce DP.

J Am Acad Dermatol. 1997 Aug;37(2 Pt 2):321-5. Review.

PMID:
9270538
21.

Mechanistic roles of neutral surfactants on concurrent polarized and passive membrane transport of a model peptide in Caco-2 cells.

Nerurkar MM, Ho NF, Burton PS, Vidmar TJ, Borchardt RT.

J Pharm Sci. 1997 Jul;86(7):813-21.

PMID:
9232522
22.

How structural features influence the biomembrane permeability of peptides.

Burton PS, Conradi RA, Ho NF, Hilgers AR, Borchardt RT.

J Pharm Sci. 1996 Dec;85(12):1336-40. Review.

PMID:
8961149
23.

Spontaneous atrophic patches in extremely premature infants. Anetoderma of prematurity.

Prizant TL, Lucky AW, Frieden IJ, Burton PS, Suarez SM.

Arch Dermatol. 1996 Jun;132(6):671-4.

PMID:
8651717
24.
25.
26.
28.

Quantitative approaches to delineate paracellular diffusion in cultured epithelial cell monolayers.

Adson A, Raub TJ, Burton PS, Barsuhn CL, Hilgers AR, Audus KL, Ho NF.

J Pharm Sci. 1994 Nov;83(11):1529-36.

PMID:
7891269
29.

Hydrogen bonding potential as a determinant of the in vitro and in situ blood-brain barrier permeability of peptides.

Chikhale EG, Ng KY, Burton PS, Borchardt RT.

Pharm Res. 1994 Mar;11(3):412-9.

PMID:
8008709
30.

Epithelial cell permeability of a series of peptidic HIV protease inhibitors: aminoterminal substituent effects.

Conradi RA, Hilgers AR, Burton PS, Hester JB.

J Drug Target. 1994;2(2):167-71.

PMID:
8069595
31.

In vitro/in vivo models for peptide oral absorption: comparison of Caco-2 cell permeability with rat intestinal absorption of renin inhibitory peptides.

Conradi RA, Wilkinson KF, Rush BD, Hilgers AR, Ruwart MJ, Burton PS.

Pharm Res. 1993 Dec;10(12):1790-2. No abstract available.

PMID:
8302767
33.

Evidence for a polarized efflux system for peptides in the apical membrane of Caco-2 cells.

Burton PS, Conradi RA, Hilgers AR, Ho NF.

Biochem Biophys Res Commun. 1993 Feb 15;190(3):760-6.

PMID:
8439326
34.

Peptides are better absorbed from the lung than the gut in the rat.

Hoover JL, Rush BD, Wilkinson KF, Day JS, Burton PS, Vidmar TJ, Ruwart MJ.

Pharm Res. 1992 Aug;9(8):1103-6. No abstract available.

PMID:
1409386
35.
36.

Desolvation energy: a major determinant of absorption, but not clearance, of peptides in rats.

Karls MS, Rush BD, Wilkinson KF, Vidmar TJ, Burton PS, Ruwart MJ.

Pharm Res. 1991 Dec;8(12):1477-81.

PMID:
1808609
37.

The influence of peptide structure on transport across Caco-2 cells.

Conradi RA, Hilgers AR, Ho NF, Burton PS.

Pharm Res. 1991 Dec;8(12):1453-60.

PMID:
1808606
38.

Caco-2 cell monolayers as a model for drug transport across the intestinal mucosa.

Hilgers AR, Conradi RA, Burton PS.

Pharm Res. 1990 Sep;7(9):902-10.

PMID:
2235888
39.

Novel membrane localized iron chelators as inhibitors of iron-dependent lipid peroxidation.

Braughler JM, Burton PS, Chase RL, Pregenzer JF, Jacobsen EJ, VanDoornik FJ, Tustin JM, Ayer DE, Bundy GL.

Biochem Pharmacol. 1988 Oct 15;37(20):3853-60.

PMID:
3190732
40.

Innovative educational changes: a paradigm.

Meleis AI, Burton PS.

Int J Nurs Stud. 1981;18(1):33-9. No abstract available.

PMID:
6906344
41.

Synthesis, absorption, and toxicity of N1,N8-bis(2,3-dihydroxybenzoyl)spermidine, a potent iron chelator.

Bergeron RJ, Burton PS, McGovern KA, St Onge EJ, Streiff RR.

J Med Chem. 1980 Oct;23(10):1130-3.

PMID:
7420358

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