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Items: 1 to 50 of 172

1.

Insights into Praziquantel metabolism and potential enantiomeric CYP-mediated drug-drug interaction.

Vendrell-Navarro G, Scheible H, Lignet F, Burt H, Luepfert C, Marx A, Abla N, Swart P, Perrin D.

Drug Metab Dispos. 2020 Mar 19. pii: dmd.119.089888. doi: 10.1124/dmd.119.089888. [Epub ahead of print]

2.

An Electronic Strategy for Eliminating Unnecessary Duplicate Genetic Testing.

Riley JD, Stanley G, Wyllie R, Burt HL, Horwitz SB, Cooper DD, Procop GW.

Am J Clin Pathol. 2020 Feb 8;153(3):328-332. doi: 10.1093/ajcp/aqz163.

PMID:
31665226
3.

Physiologically-Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug-Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations.

Taskar KS, Pilla Reddy V, Burt H, Posada MM, Varma M, Zheng M, Ullah M, Emami Riedmaier A, Umehara KI, Snoeys J, Nakakariya M, Chu X, Beneton M, Chen Y, Huth F, Narayanan R, Mukherjee D, Dixit V, Sugiyama Y, Neuhoff S.

Clin Pharmacol Ther. 2019 Oct 19. doi: 10.1002/cpt.1693. [Epub ahead of print] Review.

PMID:
31628859
4.

The use of ultrasound to increase the uptake and cytotoxicity of dual taxane and P-glycoprotein inhibitor loaded, solid core nanoparticles in drug resistant cells.

Jackson J, Leung D, Burt H.

Ultrasonics. 2020 Feb;101:106033. doi: 10.1016/j.ultras.2019.106033. Epub 2019 Sep 18.

PMID:
31561207
5.

The nested enzyme-within-enterocyte (NEWE) turnover model for predicting dynamic drug and disease effects on the gut wall.

Darwich AS, Burt HJ, Rostami-Hodjegan A.

Eur J Pharm Sci. 2019 Apr 1;131:195-207. doi: 10.1016/j.ejps.2019.02.017. Epub 2019 Feb 15.

PMID:
30776469
6.

Design and Near-Infrared Actuation of a Gold Nanorod⁻Polymer Microelectromechanical Device for On-Demand Drug Delivery.

Jackson J, Chen A, Zhang H, Burt H, Chiao M.

Micromachines (Basel). 2018 Jan 13;9(1). pii: E28. doi: 10.3390/mi9010028.

7.

Extrapolation of praziquantel pharmacokinetics to a pediatric population: a cautionary tale.

Bonate PL, Wang T, Passier P, Bagchus W, Burt H, Lüpfert C, Abla N, Kovac J, Keiser J.

J Pharmacokinet Pharmacodyn. 2018 Oct;45(5):747-762. doi: 10.1007/s10928-018-9601-1. Epub 2018 Sep 14.

8.

Enhanced taxane uptake into bladder tissues following co-administration with either mitomycin C, doxorubicin or gemcitabine: association to exfoliation processes.

Pandey R, Jackson JK, Liggins R, Mugabe C, Burt HM.

BJU Int. 2018 Nov;122(5):898-908. doi: 10.1111/bju.14423. Epub 2018 Jul 27.

9.

Cardiovascular Manifestations and Complications of Loeys-Dietz Syndrome: CT and MR Imaging Findings.

Loughborough WW, Minhas KS, Rodrigues JCL, Lyen SM, Burt HE, Manghat NE, Brooks MJ, Stuart G, Hamilton MCK.

Radiographics. 2018 Jan-Feb;38(1):275-286. doi: 10.1148/rg.2018170120. Review.

PMID:
29320330
10.

A case of kaposiform haemangioendothelioma successfully and safely treated with sirolimus.

Wlodek C, Burt H, Shaw L.

Clin Exp Dermatol. 2017 Oct;42(7):825-827. doi: 10.1111/ced.13168. Epub 2017 Jul 13. No abstract available.

PMID:
28703334
11.

Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis.

Burt HJ, Riedmaier AE, Harwood MD, Crewe HK, Gill KL, Neuhoff S.

Drug Metab Dispos. 2016 Oct;44(10):1550-61. doi: 10.1124/dmd.116.071183. Epub 2016 Aug 4.

12.
13.

Tissue Permeability Effects Associated with the Use of Mucoadhesive Cationic Nanoformulations of Docetaxel in the Bladder.

Pandey R, Jackson JK, Mugabe C, Liggins R, Burt HM.

Pharm Res. 2016 Aug;33(8):1850-61. doi: 10.1007/s11095-016-1920-6. Epub 2016 Apr 18.

PMID:
27091034
14.

Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug-drug interactions.

Burt HJ, Neuhoff S, Almond L, Gaohua L, Harwood MD, Jamei M, Rostami-Hodjegan A, Tucker GT, Rowland-Yeo K.

Eur J Pharm Sci. 2016 Jun 10;88:70-82. doi: 10.1016/j.ejps.2016.03.020. Epub 2016 Mar 25.

15.

Pancreatic cystosis in cystic fibrosis.

Burt H, Andronikou S, Langton-Hewer S.

BMJ Case Rep. 2016 Mar 4;2016. pii: bcr2015214288. doi: 10.1136/bcr-2015-214288. No abstract available.

16.

Mixed molecular weight copolymer nanoparticles for the treatment of drug-resistant tumors: formulation development and cytotoxicity.

Wan CPL, Letchford K, Leung D, Jackson JK, Burt HM.

J Pharm Sci. 2014 Dec;103(12):3966-3976. doi: 10.1002/jps.24208. Epub 2014 Oct 15.

PMID:
25318668
17.

Same-single-cell analysis using the microfluidic biochip to reveal drug accumulation enhancement by an amphiphilic diblock copolymer drug formulation.

Khamenehfar A, Wan CP, Li PC, Letchford K, Burt HM.

Anal Bioanal Chem. 2014 Nov;406(28):7071-83. doi: 10.1007/s00216-014-8151-7. Epub 2014 Oct 15.

PMID:
25315452
18.

Identification and optimization of an aminoalcohol-carbazole series with antimalarial properties.

Molette J, Routier J, Abla N, Besson D, Bombrun A, Brun R, Burt H, Georgi K, Kaiser M, Nwaka S, Muzerelle M, Scheer A.

ACS Med Chem Lett. 2013 Sep 22;4(11):1037-41. doi: 10.1021/ml400015f. eCollection 2013 Nov 14.

19.

Fabrication of robust hydrogel coatings on polydimethylsiloxane substrates using micropillar anchor structures with chemical surface modification.

Zhang H, Bian C, Jackson JK, Khademolhosseini F, Burt HM, Chiao M.

ACS Appl Mater Interfaces. 2014 Jun 25;6(12):9126-33. doi: 10.1021/am501167x. Epub 2014 Jun 5.

PMID:
24853631
20.

Fusidic acid and rifampicin co-loaded PLGA nanofibers for the prevention of orthopedic implant associated infections.

Gilchrist SE, Lange D, Letchford K, Bach H, Fazli L, Burt HM.

J Control Release. 2013 Aug 28;170(1):64-73. doi: 10.1016/j.jconrel.2013.04.012. Epub 2013 Apr 30.

PMID:
23639451
21.

The combined use of paclitaxel-loaded nanoparticles with a low-molecular-weight copolymer inhibitor of P-glycoprotein to overcome drug resistance.

Wan CP, Letchford K, Jackson JK, Burt HM.

Int J Nanomedicine. 2013;8:379-91. doi: 10.2147/IJN.S38737. Epub 2013 Jan 22.

22.

CONTROLLED DELIVERY OF ANTIANGIOGENIC DRUG TO HUMAN EYE TISSUE USING A MEMS DEVICE.

Pirmoradi FN, Ou K, Jackson JK, Letchford K, Cui J, Wolf KT, Gräber F, Zhao T, Matsubara JA, Burt H, Chiao M, Lin L.

2013 IEEE 26th Int Conf Micro Electro Mech Syst MEMS 2013 (2013). 2013 Jan;2013. pii: http://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=6474161. doi: 10.1109/MEMSYS.2013.6474161. Epub 2013 Mar 7.

23.

The use of tissue sealants to deliver antibiotics to an orthopaedic surgical site with a titanium implant.

Cashman JD, Jackson JK, Mugabe C, Gilchrist S, Ball K, Tredwell S, Burt HM.

J Orthop Sci. 2013 Jan;18(1):165-74. doi: 10.1007/s00776-012-0325-6. Epub 2012 Oct 25.

PMID:
23096950
24.

Microspheres as resistive elements in a check valve for low pressure and low flow rate conditions.

Ou K, Jackson J, Burt H, Chiao M.

Lab Chip. 2012 Nov 7;12(21):4372-80. doi: 10.1039/c2lc40652g.

PMID:
22918469
25.

Progress curve mechanistic modeling approach for assessing time-dependent inhibition of CYP3A4.

Burt HJ, Pertinez H, Säll C, Collins C, Hyland R, Houston JB, Galetin A.

Drug Metab Dispos. 2012 Sep;40(9):1658-67. doi: 10.1124/dmd.112.046078. Epub 2012 May 23.

PMID:
22621802
26.

The application of layered double hydroxide clay (LDH)-poly(lactide-co-glycolic acid) (PLGA) film composites for the controlled release of antibiotics.

Chakraborti M, Jackson JK, Plackett D, Gilchrist SE, Burt HM.

J Mater Sci Mater Med. 2012 Jul;23(7):1705-13. doi: 10.1007/s10856-012-4638-y. Epub 2012 Apr 20.

PMID:
22528072
27.

Phase separation behavior of fusidic acid and rifampicin in PLGA microspheres.

Gilchrist SE, Rickard DL, Letchford K, Needham D, Burt HM.

Mol Pharm. 2012 May 7;9(5):1489-501. doi: 10.1021/mp300099f. Epub 2012 Apr 18.

PMID:
22482935
28.

Increased accumulation and retention of micellar paclitaxel in drug-sensitive and P-glycoprotein-expressing cell lines following ultrasound exposure.

Wan CP, Jackson JK, Pirmoradi FN, Chiao M, Burt HM.

Ultrasound Med Biol. 2012 May;38(5):736-44. doi: 10.1016/j.ultrasmedbio.2012.01.023. Epub 2012 Mar 16.

PMID:
22425383
29.

Copolymer micelles and nanospheres with different in vitro stability demonstrate similar paclitaxel pharmacokinetics.

Letchford K, Burt HM.

Mol Pharm. 2012 Feb 6;9(2):248-60. doi: 10.1021/mp2002939. Epub 2012 Jan 19.

PMID:
22204437
30.

The solid-state characterization of fusidic acid.

Gilchrist SE, Letchford K, Burt HM.

Int J Pharm. 2012 Jan 17;422(1-2):245-53. doi: 10.1016/j.ijpharm.2011.11.005. Epub 2011 Nov 10.

PMID:
22100514
31.

Tissue uptake of docetaxel loaded hydrophobically derivatized hyperbranched polyglycerols and their effects on the morphology of the bladder urothelium.

Mugabe C, Raven PA, Fazli L, Baker JH, Jackson JK, Liggins RT, So AI, Gleave ME, Minchinton AI, Brooks DE, Burt HM.

Biomaterials. 2012 Jan;33(2):692-703. doi: 10.1016/j.biomaterials.2011.09.081. Epub 2011 Oct 19.

PMID:
22014457
32.

A magnetically controlled MEMS device for drug delivery: design, fabrication, and testing.

Pirmoradi FN, Jackson JK, Burt HM, Chiao M.

Lab Chip. 2011 Sep 21;11(18):3072-80. doi: 10.1039/c1lc20438f. Epub 2011 Aug 22.

PMID:
21860883
33.

Drug intercalation in layered double hydroxide clay: application in the development of a nanocomposite film for guided tissue regeneration.

Chakraborti M, Jackson JK, Plackett D, Brunette DM, Burt HM.

Int J Pharm. 2011 Sep 15;416(1):305-13. doi: 10.1016/j.ijpharm.2011.06.016. Epub 2011 Jun 17.

PMID:
21708236
34.

On-demand controlled release of docetaxel from a battery-less MEMS drug delivery device.

Pirmoradi FN, Jackson JK, Burt HM, Chiao M.

Lab Chip. 2011 Aug 21;11(16):2744-52. doi: 10.1039/c1lc20134d. Epub 2011 Jun 23.

PMID:
21698338
35.

Increased accumulation of paclitaxel and doxorubicin in proliferating capillary cells and prostate cancer cells following ultrasound exposure.

Jackson JK, Pirmoradi FN, Wan CP, Siu T, Chiao M, Burt HM.

Ultrasonics. 2011 Dec;51(8):932-9. doi: 10.1016/j.ultras.2011.05.008. Epub 2011 May 19.

PMID:
21663929
36.

The use of bone cement for the localized, controlled release of the antibiotics vancomycin, linezolid, or fusidic acid: effect of additives on drug release rates and mechanical strength.

Jackson J, Leung F, Duncan C, Mugabe C, Burt H.

Drug Deliv Transl Res. 2011 Apr;1(2):121-31. doi: 10.1007/s13346-011-0015-5.

PMID:
25788111
37.

The use of nanocrystalline cellulose for the binding and controlled release of drugs.

Jackson JK, Letchford K, Wasserman BZ, Ye L, Hamad WY, Burt HM.

Int J Nanomedicine. 2011;6:321-30. doi: 10.2147/IJN.S16749. Epub 2011 Feb 10.

38.

In vivo evaluation of mucoadhesive nanoparticulate docetaxel for intravesical treatment of non-muscle-invasive bladder cancer.

Mugabe C, Matsui Y, So AI, Gleave ME, Baker JH, Minchinton AI, Manisali I, Liggins R, Brooks DE, Burt HM.

Clin Cancer Res. 2011 May 1;17(9):2788-98. doi: 10.1158/1078-0432.CCR-10-2981. Epub 2011 Feb 28.

39.

In vitro and in vivo evaluation of intravesical docetaxel loaded hydrophobically derivatized hyperbranched polyglycerols in an orthotopic model of bladder cancer.

Mugabe C, Matsui Y, So AI, Gleave ME, Heller M, Zeisser-Labouèbe M, Heller L, Chafeeva I, Brooks DE, Burt HM.

Biomacromolecules. 2011 Apr 11;12(4):949-60. doi: 10.1021/bm101316q. Epub 2011 Mar 1.

PMID:
21355626
40.

Synthesis and characterization of carboxylic acid conjugated, hydrophobically derivatized, hyperbranched polyglycerols as nanoparticulate drug carriers for cisplatin.

Ye L, Letchford K, Heller M, Liggins R, Guan D, Kizhakkedathu JN, Brooks DE, Jackson JK, Burt HM.

Biomacromolecules. 2011 Jan 10;12(1):145-55. doi: 10.1021/bm101080p. Epub 2010 Dec 3.

PMID:
21128674
41.

Development and in vitro characterization of paclitaxel and docetaxel loaded into hydrophobically derivatized hyperbranched polyglycerols.

Mugabe C, Liggins RT, Guan D, Manisali I, Chafeeva I, Brooks DE, Heller M, Jackson JK, Burt HM.

Int J Pharm. 2011 Feb 14;404(1-2):238-49. doi: 10.1016/j.ijpharm.2010.11.010. Epub 2010 Nov 17.

PMID:
21093563
42.

The uptake of paclitaxel and docetaxel into ex vivo porcine bladder tissue from polymeric micelle formulations.

Tsallas A, Jackson J, Burt H.

Cancer Chemother Pharmacol. 2011 Aug;68(2):431-44. doi: 10.1007/s00280-010-1499-2. Epub 2010 Nov 11.

PMID:
21069339
43.

An in vitro study of plasticized poly(lactic-co-glycolic acid) films as possible guided tissue regeneration membranes: material properties and drug release kinetics.

Owen GR, Jackson JK, Chehroudi B, Brunette DM, Burt HM.

J Biomed Mater Res A. 2010 Dec 1;95(3):857-69. doi: 10.1002/jbm.a.32865.

PMID:
20824651
44.

IC50-based approaches as an alternative method for assessment of time-dependent inhibition of CYP3A4.

Burt HJ, Galetin A, Houston JB.

Xenobiotica. 2010 May;40(5):331-43. doi: 10.3109/00498251003698555.

PMID:
20230210
45.

The inhibition of collagenase induced degradation of collagen by the galloyl-containing polyphenols tannic acid, epigallocatechin gallate and epicatechin gallate.

Jackson JK, Zhao J, Wong W, Burt HM.

J Mater Sci Mater Med. 2010 May;21(5):1435-43. doi: 10.1007/s10856-010-4019-3. Epub 2010 Feb 17.

PMID:
20162329
46.

The differential in vitro and in vivo responses of bone marrow stromal cells on novel porous gelatin-alginate scaffolds.

Yang C, Frei H, Rossi FM, Burt HM.

J Tissue Eng Regen Med. 2009 Dec;3(8):601-14. doi: 10.1002/term.201.

PMID:
19685485
47.

Calcium pyrophosphate dihydrate crystal-induced inhibition of neutrophil apoptosis: involvement of Bcl-2 family members.

Higo T, Duronio V, Tudan C, Burt HM, Jackson JK.

Inflamm Res. 2010 Jan;59(1):71-81. doi: 10.1007/s00011-009-0073-z. Epub 2009 Aug 8.

PMID:
19669391
48.

Composite hydrogel formulations of stratifin to control MMP-1 expression in dermal fibroblasts.

Rahmani-Neishaboor E, Jackson J, Burt H, Ghahary A.

Pharm Res. 2009 Aug;26(8):2002-14. doi: 10.1007/s11095-009-9916-0. Epub 2009 Jun 17.

PMID:
19533306
49.

PLGA and PHBV microsphere formulations and solid-state characterization: possible implications for local delivery of fusidic acid for the treatment and prevention of orthopaedic infections.

Yang C, Plackett D, Needham D, Burt HM.

Pharm Res. 2009 Jul;26(7):1644-56. doi: 10.1007/s11095-009-9875-5. Epub 2009 Apr 21.

PMID:
19384471
50.

Effects of continuous and pulsatile PTH treatments on rat bone marrow stromal cells.

Yang C, Frei H, Burt HM, Rossi F.

Biochem Biophys Res Commun. 2009 Mar 20;380(4):791-6. doi: 10.1016/j.bbrc.2009.01.167. Epub 2009 Feb 3.

PMID:
19338754

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