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Mechanisms through which lithocholic acid delays yeast chronological aging under caloric restriction conditions.

Arlia-Ciommo A, Leonov A, Mohammad K, Beach A, Richard VR, Bourque SD, Burstein MT, Goldberg AA, Kyryakov P, Gomez-Perez A, Koupaki O, Titorenko VI.

Oncotarget. 2018 Oct 9;9(79):34945-34971. doi: 10.18632/oncotarget.26188. eCollection 2018 Oct 9.


Caloric restriction delays yeast chronological aging by remodeling carbohydrate and lipid metabolism, altering peroxisomal and mitochondrial functionalities, and postponing the onsets of apoptotic and liponecrotic modes of regulated cell death.

Arlia-Ciommo A, Leonov A, Beach A, Richard VR, Bourque SD, Burstein MT, Kyryakov P, Gomez-Perez A, Koupaki O, Feldman R, Titorenko VI.

Oncotarget. 2018 Mar 5;9(22):16163-16184. doi: 10.18632/oncotarget.24604. eCollection 2018 Mar 23.


Empirical Validation of a Hypothesis of the Hormetic Selective Forces Driving the Evolution of Longevity Regulation Mechanisms.

Gomez-Perez A, Kyryakov P, Burstein MT, Asbah N, Noohi F, Iouk T, Titorenko VI.

Front Genet. 2016 Dec 6;7:216. doi: 10.3389/fgene.2016.00216. eCollection 2016.


Frailty predicts risk of life-threatening complications and mortality after pancreatic resections.

Augustin T, Burstein MD, Schneider EB, Morris-Stiff G, Wey J, Chalikonda S, Walsh RM.

Surgery. 2016 Oct;160(4):987-996. doi: 10.1016/j.surg.2016.07.010. Epub 2016 Aug 18.


FolC2-mediated folate metabolism contributes to suppression of inflammation by probiotic Lactobacillus reuteri.

Thomas CM, Saulnier DM, Spinler JK, Hemarajata P, Gao C, Jones SE, Grimm A, Balderas MA, Burstein MD, Morra C, Roeth D, Kalkum M, Versalovic J.

Microbiologyopen. 2016 Oct;5(5):802-818. doi: 10.1002/mbo3.371. Epub 2016 Jun 28.


Disruptive Mood Dysregulation Disorder at Ages 13-18: Results from the National Comorbidity Survey-Adolescent Supplement.

Althoff RR, Crehan ET, He JP, Burstein M, Hudziak JJ, Merikangas KR.

J Child Adolesc Psychopharmacol. 2016 Mar;26(2):107-13. doi: 10.1089/cap.2015.0038. Epub 2016 Jan 15.


The Philadelphia Neurodevelopmental Cohort: constructing a deep phenotyping collaborative.

Calkins ME, Merikangas KR, Moore TM, Burstein M, Behr MA, Satterthwaite TD, Ruparel K, Wolf DH, Roalf DR, Mentch FD, Qiu H, Chiavacci R, Connolly JJ, Sleiman PMA, Gur RC, Hakonarson H, Gur RE.

J Child Psychol Psychiatry. 2015 Dec;56(12):1356-1369. doi: 10.1111/jcpp.12416. Epub 2015 Apr 8.


Comorbidity of physical and mental disorders in the neurodevelopmental genomics cohort study.

Merikangas KR, Calkins ME, Burstein M, He JP, Chiavacci R, Lateef T, Ruparel K, Gur RC, Lehner T, Hakonarson H, Gur RE.

Pediatrics. 2015 Apr;135(4):e927-38. doi: 10.1542/peds.2014-1444. Epub 2015 Mar 9.


The space of common psychiatric disorders in adolescents: comorbidity structure and individual latent liabilities.

Blanco C, Wall MM, He JP, Krueger RF, Olfson M, Jin CJ, Burstein M, Merikangas KR.

J Am Acad Child Adolesc Psychiatry. 2015 Jan;54(1):45-52. doi: 10.1016/j.jaac.2014.10.007. Epub 2014 Oct 18.


Major depression in the national comorbidity survey-adolescent supplement: prevalence, correlates, and treatment.

Avenevoli S, Swendsen J, He JP, Burstein M, Merikangas KR.

J Am Acad Child Adolesc Psychiatry. 2015 Jan;54(1):37-44.e2. doi: 10.1016/j.jaac.2014.10.010. Epub 2014 Oct 29.


Mechanism of liponecrosis, a distinct mode of programmed cell death.

Richard VR, Beach A, Piano A, Leonov A, Feldman R, Burstein MT, Kyryakov P, Gomez-Perez A, Arlia-Ciommo A, Baptista S, Campbell C, Goncharov D, Pannu S, Patrinos D, Sadri B, Svistkova V, Victor A, Titorenko VI.

Cell Cycle. 2014;13(23):3707-26. doi: 10.4161/15384101.2014.965003.


The psychosis spectrum in a young U.S. community sample: findings from the Philadelphia Neurodevelopmental Cohort.

Calkins ME, Moore TM, Merikangas KR, Burstein M, Satterthwaite TD, Bilker WB, Ruparel K, Chiavacci R, Wolf DH, Mentch F, Qiu H, Connolly JJ, Sleiman PA, Hakonarson H, Gur RC, Gur RE.

World Psychiatry. 2014 Oct;13(3):296-305. doi: 10.1002/wps.20152.


Comprehensive genomic analysis identifies novel subtypes and targets of triple-negative breast cancer.

Burstein MD, Tsimelzon A, Poage GM, Covington KR, Contreras A, Fuqua SA, Savage MI, Osborne CK, Hilsenbeck SG, Chang JC, Mills GB, Lau CC, Brown PH.

Clin Cancer Res. 2015 Apr 1;21(7):1688-98. doi: 10.1158/1078-0432.CCR-14-0432. Epub 2014 Sep 10.


Novel somatic and germline mutations in intracranial germ cell tumours.

Wang L, Yamaguchi S, Burstein MD, Terashima K, Chang K, Ng HK, Nakamura H, He Z, Doddapaneni H, Lewis L, Wang M, Suzuki T, Nishikawa R, Natsume A, Terasaka S, Dauser R, Whitehead W, Adekunle A, Sun J, Qiao Y, Marth G, Muzny DM, Gibbs RA, Leal SM, Wheeler DA, Lau CC.

Nature. 2014 Jul 10;511(7508):241-5. doi: 10.1038/nature13296. Epub 2014 Jun 4.


Pediatric data sharing in genomic research: attitudes and preferences of parents.

Burstein MD, Robinson JO, Hilsenbeck SG, McGuire AL, Lau CC.

Pediatrics. 2014 Apr;133(4):690-7. doi: 10.1542/peds.2013-1592. Epub 2014 Mar 10.


A mitochondrially targeted compound delays aging in yeast through a mechanism linking mitochondrial membrane lipid metabolism to mitochondrial redox biology.

Burstein MT, Titorenko VI.

Redox Biol. 2014 Jan 23;2:305-7. doi: 10.1016/j.redox.2014.01.011. eCollection 2014.


Threshold and subthreshold generalized anxiety disorder among US adolescents: prevalence, sociodemographic, and clinical characteristics.

Burstein M, Beesdo-Baum K, He JP, Merikangas KR.

Psychol Med. 2014 Aug;44(11):2351-62. doi: 10.1017/S0033291713002997. Epub 2014 Jan 2.


Mitochondrial membrane lipidome defines yeast longevity.

Beach A, Richard VR, Leonov A, Burstein MT, Bourque SD, Koupaki O, Juneau M, Feldman R, Iouk T, Titorenko VI.

Aging (Albany NY). 2013 Jul;5(7):551-74.


Macromitophagy is a longevity assurance process that in chronologically aging yeast limited in calorie supply sustains functional mitochondria and maintains cellular lipid homeostasis.

Richard VR, Leonov A, Beach A, Burstein MT, Koupaki O, Gomez-Perez A, Levy S, Pluska L, Mattie S, Rafesh R, Iouk T, Sheibani S, Greenwood M, Vali H, Titorenko VI.

Aging (Albany NY). 2013 Apr;5(4):234-69.


The Strengths and Difficulties Questionnaire (SDQ): the factor structure and scale validation in U.S. adolescents.

He JP, Burstein M, Schmitz A, Merikangas KR.

J Abnorm Child Psychol. 2013 May;41(4):583-95. doi: 10.1007/s10802-012-9696-6.


Specific phobia among U.S. adolescents: phenomenology and typology.

Burstein M, Georgiades K, He JP, Schmitz A, Feig E, Khazanov GK, Merikangas K.

Depress Anxiety. 2012 Dec;29(12):1072-82. doi: 10.1002/da.22008. Epub 2012 Oct 26.


Mental disorders in offspring of parents with bipolar and major depressive disorders.

Vandeleur C, Rothen S, Gholam-Rezaee M, Castelao E, Vidal S, Favre S, Ferrero F, Halfon O, Fumeaux P, Merikangas KR, Aubry JM, Burstein M, Preisig M.

Bipolar Disord. 2012 Sep;14(6):641-53. doi: 10.1111/j.1399-5618.2012.01048.x.


Integration of peroxisomes into an endomembrane system that governs cellular aging.

Beach A, Burstein MT, Richard VR, Leonov A, Levy S, Titorenko VI.

Front Physiol. 2012 Jul 17;3:283. doi: 10.3389/fphys.2012.00283. eCollection 2012.


Lithocholic acid extends longevity of chronologically aging yeast only if added at certain critical periods of their lifespan.

Burstein MT, Kyryakov P, Beach A, Richard VR, Koupaki O, Gomez-Perez A, Leonov A, Levy S, Noohi F, Titorenko VI.

Cell Cycle. 2012 Sep 15;11(18):3443-62. doi: 10.4161/cc.21754. Epub 2012 Aug 16.


Caloric restriction extends yeast chronological lifespan by altering a pattern of age-related changes in trehalose concentration.

Kyryakov P, Beach A, Richard VR, Burstein MT, Leonov A, Levy S, Titorenko VI.

Front Physiol. 2012 Jul 6;3:256. doi: 10.3389/fphys.2012.00256. eCollection 2012.


Structure of major depressive disorder in adolescents and adults in the US general population.

Lamers F, Burstein M, He JP, Avenevoli S, Angst J, Merikangas KR.

Br J Psychiatry. 2012 Aug;201:143-50. doi: 10.1192/bjp.bp.111.098079. Epub 2012 Jun 14.


Use and abuse of alcohol and illicit drugs in US adolescents: results of the National Comorbidity Survey-Adolescent Supplement.

Swendsen J, Burstein M, Case B, Conway KP, Dierker L, He J, Merikangas KR.

Arch Gen Psychiatry. 2012 Apr;69(4):390-8. doi: 10.1001/archgenpsychiatry.2011.1503.


Interspecies Chemical Signals Released into the Environment May Create Xenohormetic, Hormetic and Cytostatic Selective Forces that Drive the Ecosystemic Evolution of Longevity Regulation Mechanisms.

Burstein MT, Beach A, Richard VR, Koupaki O, Gomez-Perez A, Goldberg AA, Kyryakov P, Bourque SD, Glebov A, Titorenko VI.

Dose Response. 2012;10(1):75-82. doi: 10.2203/dose-response.11-011.Titorenko. Epub 2011 Jul 27.


Relations between parent psychopathology, family functioning, and adolescent problems in substance-abusing families: disaggregating the effects of parent gender.

Burstein M, Stanger C, Dumenci L.

Child Psychiatry Hum Dev. 2012 Aug;43(4):631-47. doi: 10.1007/s10578-012-0288-z.


Empirically derived subtypes of lifetime anxiety disorders: developmental and clinical correlates in U.S. adolescents.

Burstein M, Georgiades K, Lamers F, Swanson SA, Cui L, He JP, Avenevoli S, Merikangas KR.

J Consult Clin Psychol. 2012 Feb;80(1):102-15. doi: 10.1037/a0026069. Epub 2011 Nov 14.


Shyness versus social phobia in US youth.

Burstein M, Ameli-Grillon L, Merikangas KR.

Pediatrics. 2011 Nov;128(5):917-25. doi: 10.1542/peds.2011-1434. Epub 2011 Oct 17.


Social phobia and subtypes in the national comorbidity survey-adolescent supplement: prevalence, correlates, and comorbidity.

Burstein M, He JP, Kattan G, Albano AM, Avenevoli S, Merikangas KR.

J Am Acad Child Adolesc Psychiatry. 2011 Sep;50(9):870-80. doi: 10.1016/j.jaac.2011.06.005. Epub 2011 Jul 23.


Service utilization for lifetime mental disorders in U.S. adolescents: results of the National Comorbidity Survey-Adolescent Supplement (NCS-A).

Merikangas KR, He JP, Burstein M, Swendsen J, Avenevoli S, Case B, Georgiades K, Heaton L, Swanson S, Olfson M.

J Am Acad Child Adolesc Psychiatry. 2011 Jan;50(1):32-45. doi: 10.1016/j.jaac.2010.10.006. Epub 2010 Dec 3.


Lifetime prevalence of mental disorders in U.S. adolescents: results from the National Comorbidity Survey Replication--Adolescent Supplement (NCS-A).

Merikangas KR, He JP, Burstein M, Swanson SA, Avenevoli S, Cui L, Benjet C, Georgiades K, Swendsen J.

J Am Acad Child Adolesc Psychiatry. 2010 Oct;49(10):980-9. doi: 10.1016/j.jaac.2010.05.017. Epub 2010 Jul 31.


Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes.

Goldberg AA, Richard VR, Kyryakov P, Bourque SD, Beach A, Burstein MT, Glebov A, Koupaki O, Boukh-Viner T, Gregg C, Juneau M, English AM, Thomas DY, Titorenko VI.

Aging (Albany NY). 2010 Jul;2(7):393-414.


Parental anxiety and child symptomatology: an examination of additive and interactive effects of parent psychopathology. [corrected]

Burstein M, Ginsburg GS, Tein JY.

J Abnorm Child Psychol. 2010 Oct;38(7):897-909. doi: 10.1007/s10802-010-9415-0. Erratum in: J Abnorm Child Psychol. 2010 Oct;38(7):895.


The effect of parental modeling of anxious behaviors and cognitions in school-aged children: an experimental pilot study.

Burstein M, Ginsburg GS.

Behav Res Ther. 2010 Jun;48(6):506-15. doi: 10.1016/j.brat.2010.02.006. Epub 2010 Feb 25.


A novel function of lipid droplets in regulating longevity.

Goldberg AA, Bourque SD, Kyryakov P, Boukh-Viner T, Gregg C, Beach A, Burstein MT, Machkalyan G, Richard V, Rampersad S, Titorenko VI.

Biochem Soc Trans. 2009 Oct;37(Pt 5):1050-5. doi: 10.1042/BST0371050.


Parent psychopathology and youth internalizing symptoms in an urban community: a latent growth model analysis.

Burstein M, Ginsburg GS, Petras H, Ialongo N.

Child Psychiatry Hum Dev. 2010 Feb;41(1):61-87. doi: 10.1007/s10578-009-0152-y. Epub 2009 Aug 8.


Effect of calorie restriction on the metabolic history of chronologically aging yeast.

Goldberg AA, Bourque SD, Kyryakov P, Gregg C, Boukh-Viner T, Beach A, Burstein MT, Machkalyan G, Richard V, Rampersad S, Cyr D, Milijevic S, Titorenko VI.

Exp Gerontol. 2009 Sep;44(9):555-71. doi: 10.1016/j.exger.2009.06.001. Epub 2009 Jun 17.


Factor structure and psychometric properties of the Multidimensional Anxiety Scale for Children in an African American adolescent sample.

Kingery JN, Ginsburg GS, Burstein M.

Child Psychiatry Hum Dev. 2009 Jun;40(2):287-300. doi: 10.1007/s10578-009-0126-0. Epub 2009 Jan 23.


A comparison of outcomes between immediate and delayed repair of mandibular fractures.

Webb LS, Makhijani S, Khanna M, Burstein MJ, Falk AN, Koumanis DJ, Chao JD.

Can J Plast Surg. 2009 Winter;17(4):124-6.


Parent psychopathology, parenting, and child internalizing problems in substance-abusing families.

Burstein M, Stanger C, Kamon J, Dumenci L.

Psychol Addict Behav. 2006 Jun;20(2):97-106. doi: 10.1037/0893-164X.20.2.97.


Clinical characteristics of unexpected death among young enlisted military personnel: results of a three-decade retrospective surveillance.

Amital H, Glikson M, Burstein M, Afek A, Sinnreich R, Weiss Y, Israeli V.

Chest. 2004 Aug;126(2):528-33.


Parenting and children's externalizing problems in substance-abusing families.

Stanger C, Dumenci L, Kamon J, Burstein M.

J Clin Child Adolesc Psychol. 2004 Sep;33(3):590-600.


Cigarette smoking and hearing loss: lessons from the young adult periodic examinations in Israel (YAPEIS) database.

Sharabi Y, Reshef-Haran I, Burstein M, Eldad A.

Isr Med Assoc J. 2002 Dec;4(12):1118-20.


Limited clinical value of exercise stress test for the screening of coronary artery disease in young, asymptomatic adult men.

Livschitz S, Sharabi Y, Yushin J, Bar-On Z, Chouraqui P, Burstein M, Eldad A.

Am J Cardiol. 2000 Aug 15;86(4):462-4. No abstract available.


[Operative laparoscopy in pregnancy].

Lachman E, Schienfeld A, Boldes R, Levin S, Burstein M, Stark M.

Harefuah. 1999 Mar 1;136(5):343-6, 420. Review. Hebrew.


[Placenta accreta with placenta previa after previous cesarean sections--a growing danger in modern obstetrics].

Lachman E, Mali A, Gino G, Burstein M, Stark M.

Harefuah. 2000 Apr 16;138(8):628-31, 712. Hebrew.


Inhibition of HIV-1 replication by newly developed adamantane-containing polyanionic agents.

Burstein ME, Serbin AV, Khakhulina TV, Alymova IV, Stotskaya LL, Bogdan OP, Manukchina EE, Jdanov VV, Sharova NK, Bukrinskaya AG.

Antiviral Res. 1999 Apr;41(3):135-44.


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