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Items: 1 to 50 of 220

1.

Editing of the gut microbiota reduces carcinogenesis in mouse models of colitis-associated colorectal cancer.

Zhu W, Miyata N, Winter MG, Arenales A, Hughes ER, Spiga L, Kim J, Sifuentes-Dominguez L, Starokadomskyy P, Gopal P, Byndloss MX, Santos RL, Burstein E, Winter SE.

J Exp Med. 2019 Jul 29. pii: jem.20181939. doi: 10.1084/jem.20181939. [Epub ahead of print]

PMID:
31358565
2.

Natural compounds in the chemoprevention of alcoholic liver disease.

Tu Y, Zhu S, Wang J, Burstein E, Jia D.

Phytother Res. 2019 Jul 2. doi: 10.1002/ptr.6410. [Epub ahead of print] Review.

PMID:
31264302
3.

Mosaic Tetrasomy 9p Associated With Inflammatory Bowel Disease.

Sifuentes-Dominguez L, Starokadomskyy P, Welch J, Gurram B, Park JY, Koduru P, Burstein E.

J Crohns Colitis. 2019 Apr 25. pii: jjz079. doi: 10.1093/ecco-jcc/jjz079. [Epub ahead of print]

PMID:
31104071
4.

Defective DNA Polymerase α-Primase Leads to X-Linked Intellectual Disability Associated with Severe Growth Retardation, Microcephaly, and Hypogonadism.

Van Esch H, Colnaghi R, Freson K, Starokadomskyy P, Zankl A, Backx L, Abramowicz I, Outwin E, Rohena L, Faulkner C, Leong GM, Newbury-Ecob RA, Challis RC, Õunap K, Jaeken J, Seuntjens E, Devriendt K, Burstein E, Low KJ, O'Driscoll M.

Am J Hum Genet. 2019 May 2;104(5):957-967. doi: 10.1016/j.ajhg.2019.03.006. Epub 2019 Apr 18.

PMID:
31006512
5.

Should inverse agonists be defined by pharmacological mechanism or clinical effect?

Burstein ES.

CNS Spectr. 2019 Aug;24(4):349-351. doi: 10.1017/S1092852918001761. Epub 2019 Mar 20. No abstract available.

PMID:
30890194
6.

Impaired COMMD10-Mediated Regulation of Ly6Chi Monocyte-Driven Inflammation Disrupts Gut Barrier Function.

Mouhadeb O, Ben Shlomo S, Cohen K, Farkash I, Gruber S, Maharshak N, Halpern Z, Burstein E, Gluck N, Varol C.

Front Immunol. 2018 Nov 14;9:2623. doi: 10.3389/fimmu.2018.02623. eCollection 2018.

7.

Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation.

Miyata N, Morris LL, Chen Q, Thorne C, Singla A, Zhu W, Winter M, Melton SD, Li H, Sifuentes-Dominguez L, Llano E, Huff-Hardy K, Starokadomskyy P, Lopez A, Reese TA, Turer E, Billadeau DD, Winter SE, Burstein E.

Cell Rep. 2018 Aug 28;24(9):2342-2355. doi: 10.1016/j.celrep.2018.07.066.

8.

Epithelial Na+ Channel: Reciprocal Control by COMMD10 and Nedd4-2.

Ware AW, Cheung TT, Rasulov S, Burstein E, McDonald FJ.

Front Physiol. 2018 Jun 26;9:793. doi: 10.3389/fphys.2018.00793. eCollection 2018.

9.

A subtype-specific neuropeptide FF receptor antagonist attenuates morphine and nicotine withdrawal syndrome in the rat.

Malin DH, Henceroth MM, Elayoubi J, Campbell JR, Anderson A, Goyarzu P, Izygon J, Madison CA, Ward CP, Burstein ES.

Neurosci Lett. 2018 Sep 25;684:98-103. doi: 10.1016/j.neulet.2018.06.053. Epub 2018 Jul 5.

PMID:
29981879
10.

Expression and purification of the SNX1/SNX6 complex.

Yong X, Hu W, Zhou X, Wang J, Burstein E, Jia D.

Protein Expr Purif. 2018 Nov;151:93-98. doi: 10.1016/j.pep.2018.06.010. Epub 2018 Jun 15.

PMID:
29908913
11.

Endosomal receptor trafficking: Retromer and beyond.

Wang J, Fedoseienko A, Chen B, Burstein E, Jia D, Billadeau DD.

Traffic. 2018 Aug;19(8):578-590. doi: 10.1111/tra.12574. Epub 2018 May 21. Review.

12.

The COMMD Family Regulates Plasma LDL Levels and Attenuates Atherosclerosis Through Stabilizing the CCC Complex in Endosomal LDLR Trafficking.

Fedoseienko A, Wijers M, Wolters JC, Dekker D, Smit M, Huijkman N, Kloosterhuis N, Klug H, Schepers A, Willems van Dijk K, Levels JHM, Billadeau DD, Hofker MH, van Deursen J, Westerterp M, Burstein E, Kuivenhoven JA, van de Sluis B.

Circ Res. 2018 Jun 8;122(12):1648-1660. doi: 10.1161/CIRCRESAHA.117.312004. Epub 2018 Mar 15.

PMID:
29545368
13.

Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation.

Burger E, Araujo A, López-Yglesias A, Rajala MW, Geng L, Levine B, Hooper LV, Burstein E, Yarovinsky F.

Cell Host Microbe. 2018 Feb 14;23(2):177-190.e4. doi: 10.1016/j.chom.2018.01.001. Epub 2018 Jan 18.

14.

Precision editing of the gut microbiota ameliorates colitis.

Zhu W, Winter MG, Byndloss MX, Spiga L, Duerkop BA, Hughes ER, Büttner L, de Lima Romão E, Behrendt CL, Lopez CA, Sifuentes-Dominguez L, Huff-Hardy K, Wilson RP, Gillis CC, Tükel Ç, Koh AY, Burstein E, Hooper LV, Bäumler AJ, Winter SE.

Nature. 2018 Jan 11;553(7687):208-211. doi: 10.1038/nature25172. Epub 2018 Jan 3.

15.

Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.

McNally KE, Faulkner R, Steinberg F, Gallon M, Ghai R, Pim D, Langton P, Pearson N, Danson CM, Nägele H, Morris LL, Singla A, Overlee BL, Heesom KJ, Sessions R, Banks L, Collins BM, Berger I, Billadeau DD, Burstein E, Cullen PJ.

Nat Cell Biol. 2017 Oct;19(10):1214-1225. doi: 10.1038/ncb3610. Epub 2017 Sep 11.

16.

Efficacy of Combination Vedolizumab and Ustekinumab for Refractory Crohn's Disease.

Huff-Hardy K, Bedair M, Vazquez R, Burstein E.

Inflamm Bowel Dis. 2017 Oct;23(10):E49. doi: 10.1097/MIB.0000000000001232. No abstract available.

PMID:
28858074
17.

Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization.

Scheepstra M, Andrei SA, de Vries RMJM, Meijer FA, Ma JN, Burstein ES, Olsson R, Ottmann C, Milroy LG, Brunsveld L.

ACS Chem Neurosci. 2017 Sep 20;8(9):2065-2077. doi: 10.1021/acschemneuro.7b00216. Epub 2017 Jul 24.

18.

Cellular functions of WASP family proteins at a glance.

Alekhina O, Burstein E, Billadeau DD.

J Cell Sci. 2017 Jul 15;130(14):2235-2241. doi: 10.1242/jcs.199570. Epub 2017 Jun 23. Review.

19.

Decompression Retinopathy After Goniotomy in a Child: A Case Report.

Burstein ES, Netland PA.

J Glaucoma. 2017 Aug;26(8):747-748. doi: 10.1097/IJG.0000000000000681.

PMID:
28410254
20.

Evolution of the skin manifestations of X-linked pigmentary reticulate disorder.

Starokadomskyy P, Sifuentes-Dominguez L, Gemelli T, Zinn AR, Dossi MT, Mellado C, Bertrand P, Borzutzky A, Burstein E.

Br J Dermatol. 2017 Nov;177(5):e200-e201. doi: 10.1111/bjd.15586. Epub 2017 Oct 8. No abstract available.

21.

Dronedarone Modulates M1 and M3 Muscarinic Receptors with Subtype Selectivity, Functional Selectivity, and Probe Dependence.

Jayasuriya GM, Elmslie G, Burstein ES, Ellis J.

Pharmacology. 2017;99(3-4):128-138. doi: 10.1159/000453362. Epub 2016 Dec 20.

PMID:
27992867
22.

Structural and mechanistic insights into regulation of the retromer coat by TBC1d5.

Jia D, Zhang JS, Li F, Wang J, Deng Z, White MA, Osborne DG, Phillips-Krawczak C, Gomez TS, Li H, Singla A, Burstein E, Billadeau DD, Rosen MK.

Nat Commun. 2016 Nov 9;7:13305. doi: 10.1038/ncomms13305.

23.

Preclinical PET Neuroimaging of [11C]Bexarotene.

Rotstein BH, Placzek MS, Krishnan HS, Pekošak A, Collier TL, Wang C, Liang SH, Burstein ES, Hooker JM, Vasdev N.

Mol Imaging. 2016 Aug 23;15. pii: 1536012116663054. doi: 10.1177/1536012116663054. Print 2016.

24.

Estrogen Receptor Beta Selective Agonists as Agents to Treat Chemotherapeutic-Induced Neuropathic Pain.

Ma JN, McFarland K, Olsson R, Burstein ES.

ACS Chem Neurosci. 2016 Sep 21;7(9):1180-7. doi: 10.1021/acschemneuro.6b00183. Epub 2016 Jul 26.

PMID:
27456785
25.

Inhibiting cancer cell hallmark features through nuclear export inhibition.

Sun Q, Chen X, Zhou Q, Burstein E, Yang S, Jia D.

Signal Transduct Target Ther. 2016 Jul 1;1:16010. doi: 10.1038/sigtrans.2016.10. eCollection 2016. Review.

26.

Secondary Aortoesophageal Fistula Associated With Aneurysmal Graft Infection by Coxiella burnetii.

Okwara CJ, Petrasek J, Gibson M, Burstein E.

ACG Case Rep J. 2016 Apr 15;3(3):169-71. doi: 10.14309/crj.2016.39. eCollection 2016 Apr.

27.

DNA polymerase-α regulates the activation of type I interferons through cytosolic RNA:DNA synthesis.

Starokadomskyy P, Gemelli T, Rios JJ, Xing C, Wang RC, Li H, Pokatayev V, Dozmorov I, Khan S, Miyata N, Fraile G, Raj P, Xu Z, Xu Z, Ma L, Lin Z, Wang H, Yang Y, Ben-Amitai D, Orenstein N, Mussaffi H, Baselga E, Tadini G, Grunebaum E, Sarajlija A, Krzewski K, Wakeland EK, Yan N, de la Morena MT, Zinn AR, Burstein E.

Nat Immunol. 2016 May;17(5):495-504. doi: 10.1038/ni.3409. Epub 2016 Mar 28.

28.

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.

Bartuzi P, Billadeau DD, Favier R, Rong S, Dekker D, Fedoseienko A, Fieten H, Wijers M, Levels JH, Huijkman N, Kloosterhuis N, van der Molen H, Brufau G, Groen AK, Elliott AM, Kuivenhoven JA, Plecko B, Grangl G, McGaughran J, Horton JD, Burstein E, Hofker MH, van de Sluis B.

Nat Commun. 2016 Mar 11;7:10961. doi: 10.1038/ncomms10961.

29.

Chiral Dihydrobenzofuran Acids Show Potent Retinoid X Receptor-Nuclear Receptor Related 1 Protein Dimer Activation.

Sundén H, Schäfer A, Scheepstra M, Leysen S, Malo M, Ma JN, Burstein ES, Ottmann C, Brunsveld L, Olsson R.

J Med Chem. 2016 Feb 11;59(3):1232-8. doi: 10.1021/acs.jmedchem.5b01702. Epub 2016 Jan 28.

PMID:
26820900
30.

Endosomal sorting of Notch receptors through COMMD9-dependent pathways modulates Notch signaling.

Li H, Koo Y, Mao X, Sifuentes-Dominguez L, Morris LL, Jia D, Miyata N, Faulkner RA, van Deursen JM, Vooijs M, Billadeau DD, van de Sluis B, Cleaver O, Burstein E.

J Cell Biol. 2015 Nov 9;211(3):605-17. doi: 10.1083/jcb.201505108.

31.

Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging.

Ben-Meir A, Burstein E, Borrego-Alvarez A, Chong J, Wong E, Yavorska T, Naranian T, Chi M, Wang Y, Bentov Y, Alexis J, Meriano J, Sung HK, Gasser DL, Moley KH, Hekimi S, Casper RF, Jurisicova A.

Aging Cell. 2015 Oct;14(5):887-95. doi: 10.1111/acel.12368. Epub 2015 Jun 26.

32.

Obesity in Inflammatory Bowel Disease: A Marker of Less Severe Disease.

Flores A, Burstein E, Cipher DJ, Feagins LA.

Dig Dis Sci. 2015 Aug;60(8):2436-45. doi: 10.1007/s10620-015-3629-5. Epub 2015 Mar 24.

PMID:
25799938
33.

Methodology to study NF-κB/RelA ubiquitination in vivo.

Li H, Starokadomskyy P, Burstein E.

Methods Mol Biol. 2015;1280:371-81. doi: 10.1007/978-1-4939-2422-6_22.

PMID:
25736761
34.

Detection of IκB degradation dynamics and IκB-α ubiquitination.

Starokadomskyy P, Burstein E.

Methods Mol Biol. 2015;1280:15-24. doi: 10.1007/978-1-4939-2422-6_2.

PMID:
25736741
35.

COMMD1 regulates inflammation and colitis-associated cancer progression.

Li H, Burstein E.

Oncoimmunology. 2014 Jul 3;3(7):e947891. eCollection 2014.

36.

Reversal of morphine tolerance by a compound with NPFF receptor subtype-selective actions.

Malin DH, Henceroth MM, Izygon JJ, Nghiem DM, Moon WD, Anderson AP, Madison CA, Goyarzu P, Ma JN, Burstein ES.

Neurosci Lett. 2015 Jan 1;584:141-5. doi: 10.1016/j.neulet.2014.10.018. Epub 2014 Oct 20.

37.

COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A.

Phillips-Krawczak CA, Singla A, Starokadomskyy P, Deng Z, Osborne DG, Li H, Dick CJ, Gomez TS, Koenecke M, Zhang JS, Dai H, Sifuentes-Dominguez LF, Geng LN, Kaufmann SH, Hein MY, Wallis M, McGaughran J, Gecz J, Sluis Bv, Billadeau DD, Burstein E.

Mol Biol Cell. 2015 Jan 1;26(1):91-103. doi: 10.1091/mbc.E14-06-1073. Epub 2014 Oct 29.

38.

A cell-type-specific role for murine Commd1 in liver inflammation.

Bartuzi P, Wijshake T, Dekker DC, Fedoseienko A, Kloosterhuis NJ, Youssef SA, Li H, Shiri-Sverdlov R, Kuivenhoven JA, de Bruin A, Burstein E, Hofker MH, van de Sluis B.

Biochim Biophys Acta. 2014 Nov;1842(11):2257-65. doi: 10.1016/j.bbadis.2014.06.035. Epub 2014 Jul 27.

39.

Bimolecular affinity purification: a variation of TAP with multiple applications.

Starokadomskyy P, Burstein E.

Methods Mol Biol. 2014;1177:193-209. doi: 10.1007/978-1-4939-1034-2_15.

PMID:
24943324
40.

Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer.

Li H, Chan L, Bartuzi P, Melton SD, Weber A, Ben-Shlomo S, Varol C, Raetz M, Mao X, Starokadomskyy P, van Sommeren S, Mokadem M, Schneider H, Weisberg R, Westra HJ, Esko T, Metspalu A, Kumar V, Faubion WA, Yarovinsky F, Hofker M, Wijmenga C, Kracht M, Franke L, Aguirre V, Weersma RK, Gluck N, van de Sluis B, Burstein E.

Gastroenterology. 2014 Jul;147(1):184-195.e3. doi: 10.1053/j.gastro.2014.04.007. Epub 2014 Apr 13.

41.

On the discovery and development of pimavanserin: a novel drug candidate for Parkinson's psychosis.

Hacksell U, Burstein ES, McFarland K, Mills RG, Williams H.

Neurochem Res. 2014 Oct;39(10):2008-17. doi: 10.1007/s11064-014-1293-3. Epub 2014 Mar 30. Review.

42.

Bexarotene prodrugs: targeting through cleavage by NQO1 (DT-diaphorase).

Schäfer A, Burstein ES, Olsson R.

Bioorg Med Chem Lett. 2014 Apr 15;24(8):1944-7. doi: 10.1016/j.bmcl.2014.03.003. Epub 2014 Mar 13.

PMID:
24666648
43.

Identification of the antiarrhythmic drugs amiodarone and lorcainide as potent H3 histamine receptor inverse agonists.

Del Tredici AL, Ma JN, Piu F, Burstein ES.

J Pharmacol Exp Ther. 2014 Jan;348(1):116-24. doi: 10.1124/jpet.113.208892. Epub 2013 Nov 7.

PMID:
24204014
44.

Low dose bexarotene treatment rescues dopamine neurons and restores behavioral function in models of Parkinson's disease.

McFarland K, Spalding TA, Hubbard D, Ma JN, Olsson R, Burstein ES.

ACS Chem Neurosci. 2013 Nov 20;4(11):1430-8. doi: 10.1021/cn400100f. Epub 2013 Oct 11.

45.

The protease activated receptor 2 (PAR2) polymorphic variant F240S constitutively activates PAR2 receptors and potentiates responses to small-molecule PAR2 agonists.

Ma JN, Burstein ES.

J Pharmacol Exp Ther. 2013 Dec;347(3):697-704. doi: 10.1124/jpet.113.208744. Epub 2013 Sep 27.

PMID:
24078870
46.

Cooperation of TLR12 and TLR11 in the IRF8-dependent IL-12 response to Toxoplasma gondii profilin.

Raetz M, Kibardin A, Sturge CR, Pifer R, Li H, Burstein E, Ozato K, Larin S, Yarovinsky F.

J Immunol. 2013 Nov 1;191(9):4818-27. doi: 10.4049/jimmunol.1301301. Epub 2013 Sep 27.

47.

Paraneoplastic diarrhea in a patient with lung adenocarcinoma.

Nguyen AD, Valasek MA, Burstein E.

Clin J Gastroenterol. 2013 Oct;6(5):357-60. doi: 10.1007/s12328-013-0407-9. Epub 2013 Jul 26.

PMID:
26181831
48.

AC-186, a selective nonsteroidal estrogen receptor β agonist, shows gender specific neuroprotection in a Parkinson's disease rat model.

McFarland K, Price DL, Davis CN, Ma JN, Bonhaus DW, Burstein ES, Olsson R.

ACS Chem Neurosci. 2013 Sep 18;4(9):1249-55. doi: 10.1021/cn400132u. Epub 2013 Aug 6.

49.

Design of a highly selective and potent class of non-planar estrogen receptor β agonists.

Sundén H, Ma JN, Hansen LK, Gustavsson AL, Burstein ES, Olsson R.

ChemMedChem. 2013 Aug;8(8):1283-94. doi: 10.1002/cmdc.201300175. Epub 2013 Jun 19.

PMID:
23784708
50.

CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling.

Starokadomskyy P, Gluck N, Li H, Chen B, Wallis M, Maine GN, Mao X, Zaidi IW, Hein MY, McDonald FJ, Lenzner S, Zecha A, Ropers HH, Kuss AW, McGaughran J, Gecz J, Burstein E.

J Clin Invest. 2013 May;123(5):2244-56. doi: 10.1172/JCI66466. Epub 2013 Apr 8.

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