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Imbalance of the renin-angiotensin system may contribute to inflammation and fibrosis in IBD: a novel therapeutic target?

Garg M, Royce SG, Tikellis C, Shallue C, Batu D, Velkoska E, Burrell LM, Patel SK, Beswick L, Jackson A, Britto K, Lukies M, Sluka P, Wardan H, Hirokawa Y, Tan CW, Faux M, Burgess AW, Hosking P, Monagle S, Thomas M, Gibson PR, Lubel J.

Gut. 2019 Aug 13. pii: gutjnl-2019-318512. doi: 10.1136/gutjnl-2019-318512. [Epub ahead of print]


Winter Peaks in Heart Failure: An Inevitable or Preventable Consequence of Seasonal Vulnerability?

Stewart S, Moholdt TT, Burrell LM, Sliwa K, Mocumbi AO, McMurray JJ, Keates AK, Hawley JA.

Card Fail Rev. 2019 May 24;5(2):83-85. doi: 10.15420/cfr.2018.40.2. eCollection 2019 May. Review.


May Measurement Month 2017: an analysis of blood pressure screening results from Australia-South-East Asia and Australasia.

Carnagarin R, Fonseca R, Brockman D, Hering D, Matthews VB, Mihailidou A, Reid C, Lee R, Lambert GW, Burrell LM, Sharman JE, Xia X, Poulter NR, Beaney T, Islam SM, Carrington M, Schlaich MP.

Eur Heart J Suppl. 2019 Apr;21(Suppl D):D14-D16. doi: 10.1093/eurheartj/suz052. Epub 2019 Apr 24.


May Measurement Month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension.

Beaney T, Burrell LM, Castillo RR, Charchar FJ, Cro S, Damasceno A, Kruger R, Nilsson PM, Prabhakaran D, Ramirez AJ, Schlaich MP, Schutte AE, Tomaszewski M, Touyz R, Wang JG, Weber MA, Poulter NR; MMM Investigators .

Eur Heart J. 2019 Jul 1;40(25):2006-2017. doi: 10.1093/eurheartj/ehz300.


Plasma endothelin-1 and adrenomedullin are associated with coronary artery function and cardiovascular outcomes in humans.

Theuerle J, Farouque O, Vasanthakumar S, Patel SK, Burrell LM, Clark DJ, Al-Fiadh AH.

Int J Cardiol. 2019 Sep 15;291:168-172. doi: 10.1016/j.ijcard.2019.04.008. Epub 2019 Apr 2.


Classic and Nonclassic Renin-Angiotensin Systems in the Critically Ill.

Bitker L, Burrell LM.

Crit Care Clin. 2019 Apr;35(2):213-227. doi: 10.1016/j.ccc.2018.11.002. Epub 2019 Jan 28. Review.


Prevalence and profile of "seasonal frequent flyers" with chronic heart disease: Analysis of 1598 patients and 4588 patient-years follow-up.

Loader J, Chan YK, Hawley JA, Moholdt T, McDonald CF, Jhund P, Petrie MC, McMurray JJ, Scuffham PA, Ramchand J, Burrell LM, Stewart S.

Int J Cardiol. 2019 Mar 15;279:126-132. doi: 10.1016/j.ijcard.2018.12.060. Epub 2019 Jan 2.


Renin-angiotensin inhibitors reprogram tumor immune microenvironment: A comprehensive view of the influences on anti-tumor immunity.

Vallejo-Ardila DL, Fifis T, Burrell LM, Walsh K, Christophi C.

Oncotarget. 2018 Oct 26;9(84):35500-35511. doi: 10.18632/oncotarget.26174. eCollection 2018 Oct 26. Review.


Further studies needed before using renin-angiotensin-aldosterone system blockade for atrial fibrillation prevention in hypertrophic cardiomyopathy.

Ramchand J, Sampaio Rodrigues T, Yudi MB, Burrell LM.

Heart. 2018 Dec;104(23):1985. doi: 10.1136/heartjnl-2018-313929. No abstract available.


Routine use of HbA1c amongst inpatients hospitalised with decompensated heart failure and the association of dysglycaemia with outcomes.

Khoo K, Lew J, Neef P, Kearney L, Churilov L, Robbins R, Tan A, Hachem M, Owen-Jones L, Lam Q, Hart GK, Wilson A, Sumithran P, Johnson D, Srivastava PM, Farouque O, Burrell LM, Zajac JD, Ekinci EI.

Sci Rep. 2018 Sep 10;8(1):13564. doi: 10.1038/s41598-018-31473-8.


The small molecule drug diminazene aceturate inhibits liver injury and biliary fibrosis in mice.

Rajapaksha IG, Mak KY, Huang P, Burrell LM, Angus PW, Herath CB.

Sci Rep. 2018 Jul 5;8(1):10175. doi: 10.1038/s41598-018-28490-y.


Left ventricular hypertrophy in experimental chronic kidney disease is associated with reduced expression of cardiac Kruppel-like factor 15.

Patel SK, Velkoska E, Gayed D, Ramchand J, Lesmana J, Burrell LM.

BMC Nephrol. 2018 Jul 3;19(1):159. doi: 10.1186/s12882-018-0955-9.


Elevated plasma angiotensin converting enzyme 2 activity is an independent predictor of major adverse cardiac events in patients with obstructive coronary artery disease.

Ramchand J, Patel SK, Srivastava PM, Farouque O, Burrell LM.

PLoS One. 2018 Jun 13;13(6):e0198144. doi: 10.1371/journal.pone.0198144. eCollection 2018.


May Measurement Month 2017: an analysis of blood pressure screening results worldwide.

Beaney T, Schutte AE, Tomaszewski M, Ariti C, Burrell LM, Castillo RR, Charchar FJ, Damasceno A, Kruger R, Lackland DT, Nilsson PM, Prabhakaran D, Ramirez AJ, Schlaich MP, Wang J, Weber MA, Poulter NR; MMM Investigators.

Lancet Glob Health. 2018 Jul;6(7):e736-e743. doi: 10.1016/S2214-109X(18)30259-6. Epub 2018 May 16. Erratum in: Lancet Glob Health. 2018 May 23;:.


Low-Dose Levothyroxine Reduces Intrahepatic Lipid Content in Patients With Type 2 Diabetes Mellitus and NAFLD.

Bruinstroop E, Dalan R, Cao Y, Bee YM, Chandran K, Cho LW, Soh SB, Teo EK, Toh SA, Leow MKS, Sinha RA, Sadananthan SA, Michael N, Stapleton HM, Leung C, Angus PW, Patel SK, Burrell LM, Lim SC, Sum CF, Velan SS, Yen PM.

J Clin Endocrinol Metab. 2018 Jul 1;103(7):2698-2706. doi: 10.1210/jc.2018-00475.


Kruppel-Like Factor 15 Is Critical for the Development of Left Ventricular Hypertrophy.

Patel SK, Ramchand J, Crocitti V, Burrell LM.

Int J Mol Sci. 2018 Apr 27;19(5). pii: E1303. doi: 10.3390/ijms19051303. Review.


Development of Acute Decompensated Heart Failure Among Hospital Inpatients: Incidence, Causes and Outcomes.

Plant LD, Taylor DM, Worland T, Puri A, Ugoni A, Patel SK, Johnson DF, Burrell LM.

Heart Lung Circ. 2019 Mar;28(3):406-413. doi: 10.1016/j.hlc.2017.12.004. Epub 2017 Dec 23.


Effects of Clonidine on the Cardiovascular, Renal, and Inflammatory Responses to Experimental Bacteremia.

Calzavacca P, Booth LC, Lankadeva YR, Bailey SR, Burrell LM, Bailey M, Bellomo R, May CN.

Shock. 2019 Mar;51(3):348-355. doi: 10.1097/SHK.0000000000001134.


Author reply.

Neef PA, Burrell LM, McDonald CF, Irving LB, Johnson DF, Steinfort DP.

Intern Med J. 2018 Feb;48(2):228-229. doi: 10.1111/imj.13700. No abstract available.


Left ventricular hypertrophy and cognitive function: a systematic review.

Restrepo C, Patel SK, Rethnam V, Werden E, Ramchand J, Churilov L, Burrell LM, Brodtmann A.

J Hum Hypertens. 2018 Mar;32(3):171-179. doi: 10.1038/s41371-017-0023-0. Epub 2018 Jan 12.


The Peguero-Lo Presti Electrocardiographic Criteria Predict All-Cause Mortality in Patients With Aortic Stenosis.

Ramchand J, Sampaio Rodrigues T, Kearney LG, Patel SK, Srivastava PM, Burrell LM.

J Am Coll Cardiol. 2017 Oct 3;70(14):1831-1832. doi: 10.1016/j.jacc.2017.05.084. No abstract available.


Resveratrol Inhibits Growth of Experimental Abdominal Aortic Aneurysm Associated With Upregulation of Angiotensin-Converting Enzyme 2.

Moran CS, Biros E, Krishna SM, Wang Y, Tikellis C, Morton SK, Moxon JV, Cooper ME, Norman PE, Burrell LM, Thomas MC, Golledge J.

Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2195-2203. doi: 10.1161/ATVBAHA.117.310129. Epub 2017 Sep 21.


Sacubitril/valsartan: beyond natriuretic peptides.

Singh JSS, Burrell LM, Cherif M, Squire IB, Clark AL, Lang CC.

Heart. 2017 Oct;103(20):1569-1577. doi: 10.1136/heartjnl-2017-311295. Epub 2017 Jul 8. Review.


Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure.

Marques FZ, Prestes PR, Byars SG, Ritchie SC, Würtz P, Patel SK, Booth SA, Rana I, Minoda Y, Berzins SP, Curl CL, Bell JR, Wai B, Srivastava PM, Kangas AJ, Soininen P, Ruohonen S, Kähönen M, Lehtimäki T, Raitoharju E, Havulinna A, Perola M, Raitakari O, Salomaa V, Ala-Korpela M, Kettunen J, McGlynn M, Kelly J, Wlodek ME, Lewandowski PA, Delbridge LM, Burrell LM, Inouye M, Harrap SB, Charchar FJ.

J Am Heart Assoc. 2017 Jun 14;6(6). pii: e005971. doi: 10.1161/JAHA.117.005971.


Commencement of cardioselective beta-blockers during hospitalisation for acute exacerbations of chronic obstructive pulmonary disease.

Neef PA, Burrell LM, McDonald CF, Irving LB, Johnson DF, Steinfort DP.

Intern Med J. 2017 Sep;47(9):1043-1050. doi: 10.1111/imj.13518.


Clinical Perspective on Antihypertensive Drug Treatment in Adults With Grade 1 Hypertension and Low-to-Moderate Cardiovascular Risk: An International Expert Consultation.

Morales Salinas A, Coca A, Olsen MH, Sanchez RA, Sebba-Barroso WK, Kones R, Bertomeu-Martinez V, Sobrino J, Alcocer L, Pineiro DJ, Lanas F, Machado CA, Aguirre-Palacios F, Ortellado J, Perez G, Sabio R, Landrove O, Rodriguez-Leyva D, Duenas-Herrera A, Rodriguez Portelles A, Parra-Carrillo JZ, Piskorz DL, Bryce-Moncloa A, Waisman G, Yano Y, Ventura H, Orias M, Prabhakaran D, Sundström J, Wang J, Burrell LM, Schutte AE, Lopez-Jaramillo P, Barbosa E, Redon J, Weber MA, Lavie CJ, Ramirez A, Ordunez P, Yusuf S, Zanchetti A.

Curr Probl Cardiol. 2017 Jul;42(7):198-225. doi: 10.1016/j.cpcardiol.2017.03.001. Epub 2017 Mar 8. Review.


Genetic Variation in Kruppel like Factor 15 Is Associated with Left Ventricular Hypertrophy in Patients with Type 2 Diabetes: Discovery and Replication Cohorts.

Patel SK, Wai B, Lang CC, Levin D, Palmer CNA, Parry HM, Velkoska E, Harrap SB, Srivastava PM, Burrell LM.

EBioMedicine. 2017 Apr;18:171-178. doi: 10.1016/j.ebiom.2017.03.036. Epub 2017 Mar 30.


Does left ventricular hypertrophy affect cognition and brain structural integrity in type 2 diabetes? Study design and rationale of the Diabetes and Dementia (D2) study.

Patel SK, Restrepo C, Werden E, Churilov L, Ekinci EI, Srivastava PM, Ramchand J, Wai B, Chambers B, O'Callaghan CJ, Darby D, Hachinski V, Cumming T, Donnan G, Burrell LM, Brodtmann A.

BMC Endocr Disord. 2017 Apr 7;17(1):24. doi: 10.1186/s12902-017-0173-7.


Adverse cardiac effects of exogenous angiotensin 1-7 in rats with subtotal nephrectomy are prevented by ACE inhibition.

Burrell LM, Gayed D, Griggs K, Patel SK, Velkoska E.

PLoS One. 2017 Feb 13;12(2):e0171975. doi: 10.1371/journal.pone.0171975. eCollection 2017.


Beta-blockers are under-prescribed in patients with chronic obstructive pulmonary disease and co-morbid cardiac disease.

Neef PA, McDonald CF, Burrell LM, Irving LB, Johnson DF, Steinfort DP.

Intern Med J. 2016 Nov;46(11):1336-1340. doi: 10.1111/imj.13240.


The Receptor for Advanced Glycation End Products (RAGE) Is Associated with Persistent Atrial Fibrillation.

Lancefield TF, Patel SK, Freeman M, Velkoska E, Wai B, Srivastava PM, Horrigan M, Farouque O, Burrell LM.

PLoS One. 2016 Sep 14;11(9):e0161715. doi: 10.1371/journal.pone.0161715. eCollection 2016.


An unusual presentation of carcinomatous meningitis.

Foo CT, Burrell LM, Johnson DF.

Oxf Med Case Reports. 2016 Aug 25;2016(8):omw068. doi: 10.1093/omcr/omw068. eCollection 2016 Aug.


Diminazene Aceturate Improves Cardiac Fibrosis and Diastolic Dysfunction in Rats with Kidney Disease.

Velkoska E, Patel SK, Griggs K, Burrell LM.

PLoS One. 2016 Aug 29;11(8):e0161760. doi: 10.1371/journal.pone.0161760. eCollection 2016.


Angiotensin converting enzyme 2 and diminazene: role in cardiovascular and blood pressure regulation.

Velkoska E, Patel SK, Burrell LM.

Curr Opin Nephrol Hypertens. 2016 Sep;25(5):384-95. doi: 10.1097/MNH.0000000000000254. Review.


Is It Time to Reappraise Blood Pressure Thresholds and Targets? A Statement From the International Society of Hypertension-A Global Perspective.

Weber MA, Poulter NR, Schutte AE, Burrell LM, Horiuchi M, Prabhakaran D, Ramirez AJ, Wang JG, Schiffrin EL, Touyz RM.

Hypertension. 2016 Aug;68(2):266-8. doi: 10.1161/HYPERTENSIONAHA.116.07818. Epub 2016 Jun 27. No abstract available.


Establishing a pragmatic framework to optimise health outcomes in heart failure and multimorbidity (ARISE-HF): A multidisciplinary position statement.

Stewart S, Riegel B, Boyd C, Ahamed Y, Thompson DR, Burrell LM, Carrington MJ, Coats A, Granger BB, Hides J, Weintraub WS, Moser DK, Dickson VV, McDermott CJ, Keates AK, Rich MW.

Int J Cardiol. 2016 Jun 1;212:1-10. doi: 10.1016/j.ijcard.2016.03.001. Epub 2016 Mar 10. Review.


A rare case of Behçet disease with generalised myositis, cardiomyositis and necrotising fasciitis.

Ng F, Chiong FJ, Buchanan R, Burrell LM.

BMJ Case Rep. 2016 Jan 6;2016. pii: bcr2015211983. doi: 10.1136/bcr-2015-211983.


MicroRNAs mediate the cardioprotective effect of angiotensin-converting enzyme inhibition in acute kidney injury.

Rana I, Velkoska E, Patel SK, Burrell LM, Charchar FJ.

Am J Physiol Renal Physiol. 2015 Dec 1;309(11):F943-54. doi: 10.1152/ajprenal.00183.2015. Epub 2015 Sep 23.


Impact of nurse-mediated management on achieving blood pressure goal levels in primary care: Insights from the Valsartan Intensified Primary carE Reduction of Blood Pressure Study.

Carrington MJ, Jennings GL, Harris M, Nelson M, Schlaich M, Stocks NP, Burrell LM, Amerena J, de Looze FJ, Swemmer CH, Kurstjens NP, Stewart S; VIPER-BP Study investigators.

Eur J Cardiovasc Nurs. 2016 Oct;15(6):409-16. doi: 10.1177/1474515115591901. Epub 2015 Jun 18.


Shigella sonnei bacteraemia occurring in a young man with shigellosis.

Huynh A, McGrath C, Johnson D, Burrell LM.

BMJ Case Rep. 2015 Apr 28;2015. pii: bcr2014208875. doi: 10.1136/bcr-2014-208875.


Comment on Venskutonyte et al. Longitudinal development of left ventricular diastolic dysfunction in patients with type 2 diabetes. Diabetes Care 2014;37:3092-3097.

Burrell LM, Wai B, Srivastava PM, Patel SK.

Diabetes Care. 2015 Apr;38(4):e62-3. doi: 10.2337/dc14-2641. No abstract available.


Short-term treatment with diminazene aceturate ameliorates the reduction in kidney ACE2 activity in rats with subtotal nephrectomy.

Velkoska E, Patel SK, Griggs K, Pickering RJ, Tikellis C, Burrell LM.

PLoS One. 2015 Mar 18;10(3):e0118758. doi: 10.1371/journal.pone.0118758. eCollection 2015.


Usefulness of retinal microvascular endothelial dysfunction as a predictor of coronary artery disease.

Al-Fiadh AH, Wong TY, Kawasaki R, Clark DJ, Patel SK, Freeman M, Wilson A, Burrell LM, Farouque O.

Am J Cardiol. 2015 Mar 1;115(5):609-13. doi: 10.1016/j.amjcard.2014.12.011. Epub 2014 Dec 18.


From gene to protein-experimental and clinical studies of ACE2 in blood pressure control and arterial hypertension.

Patel SK, Velkoska E, Freeman M, Wai B, Lancefield TF, Burrell LM.

Front Physiol. 2014 Jun 24;5:227. doi: 10.3389/fphys.2014.00227. eCollection 2014. Review.


More rigorous protocol adherence to intensive structured management improves blood pressure control in primary care: results from the Valsartan Intensified Primary carE Reduction of Blood Pressure study.

Stewart S, Stocks NP, Burrell LM, de Looze FJ, Esterman A, Harris M, Hung J, Swemmer CH, Kurstjens NP, Jennings GL, Carrington MJ; VIPER-BP Study Investigators.

J Hypertens. 2014 Jun;32(6):1342-50. doi: 10.1097/HJH.0000000000000180.


Effects of renal denervation on regional hemodynamics and kidney function in experimental hyperdynamic sepsis.

Calzavacca P, Bailey M, Velkoska E, Burrell LM, Ramchandra R, Bellomo R, May CN.

Crit Care Med. 2014 Jun;42(6):e401-9. doi: 10.1097/CCM.0000000000000302.


Retinal microvascular structure and function in patients with risk factors of atherosclerosis and coronary artery disease.

Al-Fiadh AH, Farouque O, Kawasaki R, Nguyen TT, Uddin N, Freeman M, Patel SK, Burrell LM, Wong TY.

Atherosclerosis. 2014 Apr;233(2):478-84. doi: 10.1016/j.atherosclerosis.2013.12.044. Epub 2014 Jan 18.


Upregulation of circulating components of the alternative renin-angiotensin system in inflammatory bowel disease: A pilot study.

Garg M, Burrell LM, Velkoska E, Griggs K, Angus PW, Gibson PR, Lubel JS.

J Renin Angiotensin Aldosterone Syst. 2015 Sep;16(3):559-69. doi: 10.1177/1470320314521086. Epub 2014 Feb 6.


The International Society of Hypertension and World Hypertension League call on governments, nongovernmental organizations and the food industry to work to reduce dietary sodium.

Campbell NR, Lackland DT, Chockalingam A, Lisheng L, Harrap SB, Touyz RM, Burrell LM, Ramírez AJ, Schmieder RE, Schutte AE, Prabhakaran D, Schiffrin EL; Executive Board of the World Hypertension League:; Executive Committee of the International Society of Hypertension:.

J Hypertens. 2014 Feb;32(2):446-7. doi: 10.1097/HJH.0000000000000079.


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