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The Importance of Biologically Active Vitamin D for Mineralization by Osteocytes After Parathyroidectomy for Renal Hyperparathyroidism.

Yajima A, Tsuchiya K, Burr DB, Wallace JM, Damrath JD, Inaba M, Tominaga Y, Satoh S, Nakayama T, Tanizawa T, Ogawa H, Ito A, Nitta K.

JBMR Plus. 2019 Oct 23;3(11):e10234. doi: 10.1002/jbm4.10234. eCollection 2019 Nov.


Voluntary Chronic Heavy Alcohol Consumption in Male Rhesus Macaques Suppresses Cancellous Bone Formation and Increases Bone Marrow Adiposity.

Kahler-Quesada AM, Grant KA, Walter NAR, Newman N, Allen MR, Burr DB, Branscum AJ, Maddalozzo GF, Turner RT, Iwaniec UT.

Alcohol Clin Exp Res. 2019 Sep 26. doi: 10.1111/acer.14202. [Epub ahead of print]


Stress concentrations and bone microdamage: John Currey's contributions to understanding the initiation and arrest of cracks in bone.

Burr DB.

Bone. 2019 Oct;127:517-525. doi: 10.1016/j.bone.2019.07.015. Epub 2019 Jul 22.


Loss of Nmp4 optimizes osteogenic metabolism and secretion to enhance bone quality.

Shao Y, Wichern E, Childress PJ, Adaway M, Misra J, Klunk A, Burr DB, Wek RC, Mosley AL, Liu Y, Robling AG, Brustovetsky N, Hamilton J, Jacobs K, Vashishth D, Stayrook KR, Allen MR, Wallace JM, Bidwell JP.

Am J Physiol Endocrinol Metab. 2019 May 1;316(5):E749-E772. doi: 10.1152/ajpendo.00343.2018. Epub 2019 Jan 15.


Changes in bone matrix properties with aging.

Burr DB.

Bone. 2019 Mar;120:85-93. doi: 10.1016/j.bone.2018.10.010. Epub 2018 Oct 10.


Teriparatide Treatment Increases Mineral Content and Volume in Cortical and Trabecular Bone of Iliac Crest: A Comparison of Infrared Imaging With X-Ray-Based Bone Assessment Techniques.

Paschalis EP, Krege JH, Gamsjaeger S, Eriksen EF, Burr DB, Disch DP, Stepan JJ, Fahrleitner-Pammer A, Klaushofer K, Marin F, Pavo I.

J Bone Miner Res. 2018 Dec;33(12):2230-2235. doi: 10.1002/jbmr.3565. Epub 2018 Sep 14.


Microcrack-associated bone remodeling is rarely observed in biopsies from athletes with medial tibial stress syndrome.

Winters M, Burr DB, van der Hoeven H, Condon KW, Bellemans J, Moen MH.

J Bone Miner Metab. 2019 May;37(3):496-502. doi: 10.1007/s00774-018-0945-9. Epub 2018 Jul 31.


Osteocytic perilacunar/canalicular turnover in hemodialysis patients with high and low serum PTH levels.

Yajima A, Tsuchiya K, Burr DB, Minner DE, Condon KW, Miller CA, Satoh S, Inaba M, Nakayama T, Tanizawa T, Ito A, Nitta K.

Bone. 2018 Aug;113:68-76. doi: 10.1016/j.bone.2018.05.002. Epub 2018 May 5.


Inhibition of CaMKK2 Enhances Fracture Healing by Stimulating Indian Hedgehog Signaling and Accelerating Endochondral Ossification.

Williams JN, Kambrath AV, Patel RB, Kang KS, Mével E, Li Y, Cheng YH, Pucylowski AJ, Hassert MA, Voor MJ, Kacena MA, Thompson WR, Warden SJ, Burr DB, Allen MR, Robling AG, Sankar U.

J Bone Miner Res. 2018 May;33(5):930-944. doi: 10.1002/jbmr.3379. Epub 2018 Feb 5.


Editorial: Wnt Signaling Related to Subchondral Bone Density and Cartilage Degradation in Osteoarthritis.

Burr DB, Utreja A.

Arthritis Rheumatol. 2018 Feb;70(2):157-161. doi: 10.1002/art.40382. Epub 2018 Jan 9. No abstract available.


Effects of combination treatment with alendronate and raloxifene on skeletal properties in a beagle dog model.

Allen MR, McNerny E, Aref M, Organ JM, Newman CL, McGowan B, Jang T, Burr DB, Brown DM, Hammond M, Territo PR, Lin C, Persohn S, Jiang L, Riley AA, McCarthy BP, Hutchins GD, Wallace JM.

PLoS One. 2017 Aug 9;12(8):e0181750. doi: 10.1371/journal.pone.0181750. eCollection 2017.


Improving Combination Osteoporosis Therapy in a Preclinical Model of Heightened Osteoanabolism.

Shao Y, Hernandez-Buquer S, Childress P, Stayrook KR, Alvarez MB, Davis H, Plotkin LI, He Y, Condon KW, Burr DB, Warden SJ, Robling AG, Yang FC, Wek RC, Allen MR, Bidwell JP.

Endocrinology. 2017 Sep 1;158(9):2722-2740. doi: 10.1210/en.2017-00355.


Response to PD Miller, Underdiagnosis and Undertreatment of Osteoporosis: The Battle To Be Won.

Burr DB, Lane JE, Howe TS, Ng AC, Ebeling PR.

J Clin Endocrinol Metab. 2017 Mar 1;102(3):1088-1089. doi: 10.1210/jc.2016-2189. No abstract available.


STING Contributes to Abnormal Bone Formation Induced by Deficiency of DNase II in Mice.

Baum R, Sharma S, Organ JM, Jakobs C, Hornung V, Burr DB, Marshak-Rothstein A, Fitzgerald KA, Gravallese EM.

Arthritis Rheumatol. 2017 Feb;69(2):460-471. doi: 10.1002/art.39863.


Corrigendum to "Structural features underlying raloxifene's biophysical interaction with bone matrix" [Bioorg. Med. Chem. 24 (2016) 759-767].

Bivi N, Hu H, Chavali B, Chalmers MJ, Reutter CT, Durst GL, Riley A, Sato M, Allen MR, Burr DB, Dodge JA.

Bioorg Med Chem. 2016 Sep 15;24(18):4516. doi: 10.1016/j.bmc.2016.07.014. Epub 2016 Jul 14. No abstract available.


The use of finite element analysis to estimate the changing strength of bone following treatment for osteoporosis.

Burr DB.

Osteoporos Int. 2016 Sep;27(9):2651-2654. doi: 10.1007/s00198-016-3707-3. Epub 2016 Jul 22. No abstract available.


Corrigendum to "The resistance of cortical bone tissue to failure under cyclic loading is reduced with alendronate"[Bone 64 (2014) 57-64].

Bajaj D, Geissler JR, Allen MR, Burr DB, Fritton JC.

Bone. 2016 Feb;83:283. doi: 10.1016/j.bone.2015.03.009. Epub 2015 Mar 27. No abstract available.


Structural features underlying raloxifene's biophysical interaction with bone matrix.

Bivi N, Hu H, Chavali B, Chalmers MJ, Reutter CT, Durst GL, Riley A, Sato M, Allen MR, Burr DB, Dodge JA.

Bioorg Med Chem. 2016 Feb 15;24(4):759-67. doi: 10.1016/j.bmc.2015.12.045. Epub 2015 Dec 29. Erratum in: Bioorg Med Chem. 2016 Sep 15;24(18):4516.


Alendronate treatment alters bone tissues at multiple structural levels in healthy canine cortical bone.

Acevedo C, Bale H, Gludovatz B, Wat A, Tang SY, Wang M, Busse B, Zimmermann EA, Schaible E, Allen MR, Burr DB, Ritchie RO.

Bone. 2015 Dec;81:352-363. doi: 10.1016/j.bone.2015.08.002. Epub 2015 Aug 5.


Microbial osteolysis in an Early Pleistocene hominin (Paranthropus robustus) from Swartkrans, South Africa.

Grine FE, Bromage TG, Daegling DJ, Burr DB, Brain CK.

J Hum Evol. 2015 Aug;85:126-35. doi: 10.1016/j.jhevol.2015.05.004. Epub 2015 Jun 18.


Foreword: Calcified Tissue International and Musculoskeletal Research Special Issue: Bone Material Properties and Skeletal Fragility.

Burr DB, Allen MR.

Calcif Tissue Int. 2015 Sep;97(3):199-200. doi: 10.1007/s00223-015-0012-7. Epub 2015 May 13. No abstract available.


Understanding the etiology of the posteromedial tibial stress fracture.

Milgrom C, Burr DB, Finestone AS, Voloshin A.

Bone. 2015 Sep;78:11-4. doi: 10.1016/j.bone.2015.04.033. Epub 2015 Apr 28.


Response to Courtney et al.

Bajaj D, Geissler JR, Allen MR, Burr DB, Fritton JC.

Bone. 2016 Aug;89:77-79. doi: 10.1016/j.bone.2015.03.007. Epub 2015 Mar 24. No abstract available.


In Vivo UTE-MRI Reveals Positive Effects of Raloxifene on Skeletal-Bound Water in Skeletally Mature Beagle Dogs.

Allen MR, Territo PR, Lin C, Persohn S, Jiang L, Riley AA, McCarthy BP, Newman CL, Burr DB, Hutchins GD.

J Bone Miner Res. 2015 Aug;30(8):1441-4. doi: 10.1002/jbmr.2470. Epub 2015 May 21.


Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone.

Tu X, Delgado-Calle J, Condon KW, Maycas M, Zhang H, Carlesso N, Taketo MM, Burr DB, Plotkin LI, Bellido T.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E478-86. doi: 10.1073/pnas.1409857112. Epub 2015 Jan 20.


The complex relationship between bone remodeling and the physical and material properties of bone.

Burr DB.

Osteoporos Int. 2015 Mar;26(3):845-7. doi: 10.1007/s00198-014-2970-4. Epub 2014 Dec 20. No abstract available.


Repair mechanisms for microdamage in bone.

Burr DB.

J Bone Miner Res. 2014 Dec;29(12):2534-6. doi: 10.1002/jbmr.2366. No abstract available. Erratum in: J Bone Miner Res. 2015 Feb;30(2):395.


Treatment with eldecalcitol positively affects mineralization, microdamage, and collagen crosslinks in primate bone.

Saito M, Grynpas MD, Burr DB, Allen MR, Smith SY, Doyle N, Amizuka N, Hasegawa T, Kida Y, Marumo K, Saito H.

Bone. 2015 Apr;73:8-15. doi: 10.1016/j.bone.2014.11.025. Epub 2014 Dec 5.


Duration-dependent effects of clinically relevant oral alendronate doses on cortical bone toughness in beagle dogs.

Burr DB, Liu Z, Allen MR.

Bone. 2015 Feb;71:58-62. doi: 10.1016/j.bone.2014.10.010. Epub 2014 Oct 23.


Raloxifene prevents skeletal fragility in adult female Zucker Diabetic Sprague-Dawley rats.

Hill Gallant KM, Gallant MA, Brown DM, Sato AY, Williams JN, Burr DB.

PLoS One. 2014 Sep 22;9(9):e108262. doi: 10.1371/journal.pone.0108262. eCollection 2014.


The resistance of cortical bone tissue to failure under cyclic loading is reduced with alendronate.

Bajaj D, Geissler JR, Allen MR, Burr DB, Fritton JC.

Bone. 2014 Jul;64:57-64. doi: 10.1016/j.bone.2014.03.045. Epub 2014 Apr 1. Erratum in: Bone. 2016 Feb;83:283. Erratum in: Bone. 2016 Feb;83:283.


Bone cell-independent benefits of raloxifene on the skeleton: a novel mechanism for improving bone material properties.

Gallant MA, Brown DM, Hammond M, Wallace JM, Du J, Deymier-Black AC, Almer JD, Stock SR, Allen MR, Burr DB.

Bone. 2014 Apr;61:191-200. doi: 10.1016/j.bone.2014.01.009. Epub 2014 Jan 24.


Multiscale analysis of morphology and mechanics in tail tendon from the ZDSD rat model of type 2 diabetes.

Gonzalez AD, Gallant MA, Burr DB, Wallace JM.

J Biomech. 2014 Feb 7;47(3):681-6. doi: 10.1016/j.jbiomech.2013.11.045. Epub 2013 Dec 6.


Nanoscale changes in collagen are reflected in physical and mechanical properties of bone at the microscale in diabetic rats.

Hammond MA, Gallant MA, Burr DB, Wallace JM.

Bone. 2014 Mar;60:26-32. doi: 10.1016/j.bone.2013.11.015. Epub 2013 Nov 21.


Beyond the decade: strategic priorities to reduce the burden of musculoskeletal disease.

Jacobs JJ, King TR, Klippel JH, Berven SH, Burr DB, Caskey PM, Elderkin AL, Esposito PW, Gall EP, Goldring SR, Pollak AN, Sandborg CI, Templeton KJ.

J Bone Joint Surg Am. 2013 Sep 4;95(17):e1251-6. doi: 10.2106/JBJS.L.01370. No abstract available.


In vivo reference point indentation reveals positive effects of raloxifene on mechanical properties following 6 months of treatment in skeletally mature beagle dogs.

Aref M, Gallant MA, Organ JM, Wallace JM, Newman CL, Burr DB, Brown DM, Allen MR.

Bone. 2013 Oct;56(2):449-53. doi: 10.1016/j.bone.2013.07.009. Epub 2013 Jul 17.


Proposed pathogenesis for atypical femoral fractures: lessons from materials research.

Ettinger B, Burr DB, Ritchie RO.

Bone. 2013 Aug;55(2):495-500. doi: 10.1016/j.bone.2013.02.004. Epub 2013 Feb 16.


Reference-point indentation correlates with bone toughness assessed using whole-bone traditional mechanical testing.

Gallant MA, Brown DM, Organ JM, Allen MR, Burr DB.

Bone. 2013 Mar;53(1):301-5. doi: 10.1016/j.bone.2012.12.015. Epub 2012 Dec 27.


Circulating αKlotho influences phosphate handling by controlling FGF23 production.

Smith RC, O'Bryan LM, Farrow EG, Summers LJ, Clinkenbeard EL, Roberts JL, Cass TA, Saha J, Broderick C, Ma YL, Zeng QQ, Kharitonenkov A, Wilson JM, Guo Q, Sun H, Allen MR, Burr DB, Breyer MD, White KE.

J Clin Invest. 2012 Dec;122(12):4710-5. doi: 10.1172/JCI64986. Epub 2012 Nov 26.


Microcrack density and nanomechanical properties in the subchondral region of the immature piglet femoral head following ischemic osteonecrosis.

Aruwajoye OO, Patel MK, Allen MR, Burr DB, Aswath PB, Kim HK.

Bone. 2013 Feb;52(2):632-9. doi: 10.1016/j.bone.2012.07.028. Epub 2012 Aug 3.


Bone remodelling in osteoarthritis.

Burr DB, Gallant MA.

Nat Rev Rheumatol. 2012 Nov;8(11):665-73. doi: 10.1038/nrrheum.2012.130. Epub 2012 Aug 7. Review.


Bisphosphonate binding affinity affects drug distribution in both intracortical and trabecular bone of rabbits.

Turek J, Ebetino FH, Lundy MW, Sun S, Kashemirov BA, McKenna CE, Gallant MA, Plotkin LI, Bellido T, Duan X, Triffitt JT, Russell RG, Burr DB, Allen MR.

Calcif Tissue Int. 2012 Mar;90(3):202-10. doi: 10.1007/s00223-012-9570-0. Epub 2012 Jan 17.


Three years of alendronate treatment does not continue to decrease microstructural stresses and strains associated with trabecular microdamage initiation beyond those at 1 year.

Green JO, Diab T, Allen MR, Vidakovic B, Burr DB, Guldberg RE.

Osteoporos Int. 2012 Sep;23(9):2313-20. doi: 10.1007/s00198-011-1875-8. Epub 2012 Jan 12.


Resolution of inflammation induces osteoblast function and regulates the Wnt signaling pathway.

Matzelle MM, Gallant MA, Condon KW, Walsh NC, Manning CA, Stein GS, Lian JB, Burr DB, Gravallese EM.

Arthritis Rheum. 2012 May;64(5):1540-50. doi: 10.1002/art.33504.


Why bones bend but don't break.

Burr DB.

J Musculoskelet Neuronal Interact. 2011 Dec;11(4):270-85. Review.


Increased strontium uptake in trabecular bone of ovariectomized calcium-deficient rats treated with strontium ranelate or strontium chloride.

Pemmer B, Hofstaetter JG, Meirer F, Smolek S, Wobrauschek P, Simon R, Fuchs RK, Allen MR, Condon KW, Reinwald S, Phipps RJ, Burr DB, Paschalis EP, Klaushofer K, Streli C, Roschger P.

J Synchrotron Radiat. 2011 Nov;18(Pt 6):835-41. doi: 10.1107/S090904951103038X. Epub 2011 Sep 15.


Issues in modern bone histomorphometry.

Recker RR, Kimmel DB, Dempster D, Weinstein RS, Wronski TJ, Burr DB.

Bone. 2011 Nov;49(5):955-64. doi: 10.1016/j.bone.2011.07.017. Epub 2011 Jul 23. Review.


Bisphosphonates do not alter the rate of secondary mineralization.

Fuchs RK, Faillace ME, Allen MR, Phipps RJ, Miller LM, Burr DB.

Bone. 2011 Oct;49(4):701-5. doi: 10.1016/j.bone.2011.05.009. Epub 2011 May 18.


Treatment with connexin 46 siRNA suppresses the growth of human Y79 retinoblastoma cell xenografts in vivo.

Burr DB, Molina SA, Banerjee D, Low DM, Takemoto DJ.

Exp Eye Res. 2011 Apr;92(4):251-9. doi: 10.1016/j.exer.2011.02.003. Epub 2011 Feb 12.


Charles Hall Turner: 1961-2010.

Robling AG, Burr DB.

J Bone Miner Res. 2011 Jan;26(1):1-2. doi: 10.1002/jbmr.303. No abstract available.

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