Burns TF[au] - PubMed

Search results

Items: 1 to 50 of 55

<< First< Prev

Page of 2

Select item 317391841.

Phase 2 study of the focal adhesion kinase inhibitor defactinib (VS-6063) in previously treated advanced KRAS mutant non-small cell lung cancer.

Gerber DE, Camidge DR, Morgensztern D, Cetnar J, Kelly RJ, Ramalingam SS, Spigel DR, Jeong W, Scaglioni PP, Zhang S, Li M, Weaver DT, Vaikus L, Keegan M, Horobin JC, Burns TF.

Lung Cancer. 2019 Nov 4;139:60-67. doi: 10.1016/j.lungcan.2019.10.033. [Epub ahead of print]

PMID:: 31739184

Similar articles

Select item 313611692.

The estrogen pathway as a modulator of response to immunotherapy.

Velez MA, Burns TF, Stabile LP.

Immunotherapy. 2019 Sep;11(13):1161-1176. doi: 10.2217/imt-2019-0024. Epub 2019 Jul 30.

PMID:: 31361169

Similar articles

Select item 307984223.

SNAIL is induced by tamoxifen and leads to growth inhibition in invasive lobular breast carcinoma.

Bossart EA, Tasdemir N, Sikora MJ, Bahreini A, Levine KM, Chen J, Basudan A, Jacobsen BM, Burns TF, Oesterreich S.

Breast Cancer Res Treat. 2019 Jun;175(2):327-337. doi: 10.1007/s10549-019-05161-8. Epub 2019 Feb 23.

PMID:: 30798422

Similar articles

Select item 307340264.

TWIST1 regulation of circRNA: a novel mechanism to promote epithelial-mesenchymal transition in hepatocellular carcinoma.

Yochum ZA, Burns TF.

Noncoding RNA Investig. 2018 Dec;2. pii: 71. doi: 10.21037/ncri.2018.12.01. Epub 2018 Dec 19. No abstract available.

PMID:: 30734026

Free PMC Article

Similar articles

Select item 306155505.

Survival Outcomes of Younger Patients With Mantle Cell Lymphoma Treated in the Rituximab Era.

Gerson JN, Handorf E, Villa D, Gerrie AS, Chapani P, Li S, Medeiros LJ, Wang MI, Cohen JB, Calzada O, Churnetski MC, Hill BT, Sawalha Y, Hernandez-Ilizaliturri FJ, Kothari S, Vose JM, Bast MA, Fenske TS, Narayana Rao Gari S, Maddocks KJ, Bond D, Bachanova V, Kolla B, Chavez J, Shah B, Lansigan F, Burns TF, Donovan AM, Wagner-Johnston N, Messmer M, Mehta A, Anderson JK, Reddy N, Kovach AE, Landsburg DJ, Glenn M, Inwards DJ, Karmali R, Kaplan JB, Caimi PF, Rajguru S, Evens A, Klein A, Umyarova E, Pulluri B, Amengual JE, Lue JK, Diefenbach C, Fisher RI, Barta SK.

J Clin Oncol. 2019 Feb 20;37(6):471-480. doi: 10.1200/JCO.18.00690. Epub 2019 Jan 7.

PMID:: 30615550

Similar articles

Select item 301712586.

Targeting the EMT transcription factor TWIST1 overcomes resistance to EGFR inhibitors in EGFR-mutant non-small-cell lung cancer.

Yochum ZA, Cades J, Wang H, Chatterjee S, Simons BW, O'Brien JP, Khetarpal SK, Lemtiri-Chlieh G, Myers KV, Huang EH, Rudin CM, Tran PT, Burns TF.

Oncogene. 2019 Jan;38(5):656-670. doi: 10.1038/s41388-018-0482-y. Epub 2018 Aug 31.

PMID:: 30171258

Free PMC Article

Similar articles

Select item 300305697.

Cytogenetically cryptic insertion of PML segment into RARA on chromosome 17q resulting PML-RARA fusion in acute promyelocytic leukemia.

Burns TF, Loo EY, Bengtson EM, Bao L.

Ann Hematol. 2019 Jan;98(1):211-213. doi: 10.1007/s00277-018-3399-1. Epub 2018 Jul 20. No abstract available.

PMID:: 30030569

Similar articles

Select item 298806138.

Real-world outcomes and management strategies for venetoclax-treated chronic lymphocytic leukemia patients in the United States.

Mato AR, Thompson M, Allan JN, Brander DM, Pagel JM, Ujjani CS, Hill BT, Lamanna N, Lansigan F, Jacobs R, Shadman M, Skarbnik AP, Pu JJ, Barr PM, Sehgal AR, Cheson BD, Zent CS, Tuncer HH, Schuster SJ, Pickens PV, Shah NN, Goy A, Winter AM, Garcia C, Kennard K, Isaac K, Dorsey C, Gashonia LM, Singavi AK, Roeker LE, Zelenetz A, Williams A, Howlett C, Weissbrot H, Ali N, Khajavian S, Sitlinger A, Tranchito E, Rhodes J, Felsenfeld J, Bailey N, Patel B, Burns TF, Yacur M, Malhotra M, Svoboda J, Furman RR, Nabhan C.

Haematologica. 2018 Sep;103(9):1511-1517. doi: 10.3324/haematol.2018.193615. Epub 2018 Jun 7.

PMID:: 29880613

Free PMC Article

Similar articles

Select item 295617059.

HSP90 inhibition targets autophagy and induces a CASP9-dependent resistance mechanism in NSCLC.

Han J, Goldstein LA, Hou W, Chatterjee S, Burns TF, Rabinowich H.

Autophagy. 2018;14(6):958-971. doi: 10.1080/15548627.2018.1434471. Epub 2018 Mar 21.

PMID:: 29561705

Free PMC Article

Similar articles

Select item 2924700410.

Caveolin-1 promotes the tumor suppressor properties of oncogene-induced cellular senescence.

Volonte D, Vyas AR, Chen C, Dacic S, Stabile LP, Kurland BF, Abberbock SR, Burns TF, Herman JG, Di YP, Galbiati F.

J Biol Chem. 2018 Feb 2;293(5):1794-1809. doi: 10.1074/jbc.M117.815902. Epub 2017 Dec 15.

PMID:: 29247004

Free PMC Article

Similar articles

Select item 2916731411.

Wnt/β-Catenin Pathway Activation Mediates Adaptive Resistance to BRAF Inhibition in Colorectal Cancer.

Chen G, Gao C, Gao X, Zhang DH, Kuan SF, Burns TF, Hu J.

Mol Cancer Ther. 2018 Apr;17(4):806-813. doi: 10.1158/1535-7163.MCT-17-0561. Epub 2017 Nov 22.

PMID:: 29167314

Free PMC Article

Similar articles

Select item 2898903912.

First-Line Osimertinib in Patients with Treatment-Naive Somatic or Germline EGFR T790M-Mutant Metastatic NSCLC.

Ancevski Hunter K, Friedland DM, Villaruz LC, Burns TF.

J Thorac Oncol. 2018 Jan;13(1):e3-e5. doi: 10.1016/j.jtho.2017.09.1963. Epub 2017 Oct 5. No abstract available.

PMID:: 28989039

Free Article

Similar articles

Select item 2891477413.

Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach.

Chatterjee S, Burns TF.

Int J Mol Sci. 2017 Sep 15;18(9). pii: E1978. doi: 10.3390/ijms18091978. Review.

PMID:: 28914774

Free PMC Article

Similar articles

Select item 2889996914.

TMEM16A/ANO1 Inhibits Apoptosis Via Downregulation of Bim Expression.

Godse NR, Khan N, Yochum ZA, Gomez-Casal R, Kemp C, Shiwarski DJ, Seethala RS, Kulich S, Seshadri M, Burns TF, Duvvuri U.

Clin Cancer Res. 2017 Dec 1;23(23):7324-7332. doi: 10.1158/1078-0432.CCR-17-1561. Epub 2017 Sep 12.

PMID:: 28899969

Free PMC Article

Similar articles

Select item 2885181215.

A First-in-Class TWIST1 Inhibitor with Activity in Oncogene-Driven Lung Cancer.

Yochum ZA, Cades J, Mazzacurati L, Neumann NM, Khetarpal SK, Chatterjee S, Wang H, Attar MA, Huang EH, Chatley SN, Nugent K, Somasundaram A, Engh JA, Ewald AJ, Cho YJ, Rudin CM, Tran PT, Burns TF.

Mol Cancer Res. 2017 Dec;15(12):1764-1776. doi: 10.1158/1541-7786.MCR-17-0298. Epub 2017 Aug 29.

PMID:: 28851812

Free PMC Article

Similar articles

Select item 2861459116.

Core Entrustable Professional Activities in Clinical Pharmacology for Entering Residency: Biologics.

Donnenberg VS, Mandic M, Rhee JC, Burns TF, Meibohm B, Korth-Bradley JM.

J Clin Pharmacol. 2017 Aug;57(8):947-955. doi: 10.1002/jcph.938. Epub 2017 Jun 14. Review.

PMID:: 28614591

Similar articles

Select item 2856643617.

Reactivation of the p90RSK-CDC25C Pathway Leads to Bypass of the Ganetespib-Induced G₂-M Arrest and Mediates Acquired Resistance to Ganetespib in KRAS-Mutant NSCLC.

Chatterjee S, Huang EH, Christie I, Burns TF.

Mol Cancer Ther. 2017 Aug;16(8):1658-1668. doi: 10.1158/1535-7163.MCT-17-0114. Epub 2017 May 31.

PMID:: 28566436

Free PMC Article

Similar articles

Select item 2847253718.

Phase 1/2 study of rilotumumab (AMG 102), a hepatocyte growth factor inhibitor, and erlotinib in patients with advanced non-small cell lung cancer.

Tarhini AA, Rafique I, Floros T, Tran P, Gooding WE, Villaruz LC, Burns TF, Friedland DM, Petro DP, Farooqui M, Gomez-Garcia J, Gaither-Davis A, Dacic S, Argiris A, Socinski MA, Stabile LP, Siegfried JM.

Cancer. 2017 Aug 1;123(15):2936-2944. doi: 10.1002/cncr.30717. Epub 2017 May 4.

PMID:: 28472537

Free PMC Article

Similar articles

Select item 2843439919.

The next generation of immunotherapy: keeping lung cancer in check.

Somasundaram A, Burns TF.

J Hematol Oncol. 2017 Apr 24;10(1):87. doi: 10.1186/s13045-017-0456-5. Review.

PMID:: 28434399

Free PMC Article

Similar articles

Select item 2829312320.

Pembrolizumab in the treatment of metastatic non-small-cell lung cancer: patient selection and perspectives.

Somasundaram A, Burns TF.

Lung Cancer (Auckl). 2017 Jan 11;8:1-11. doi: 10.2147/LCTT.S105678. eCollection 2017. Review.

PMID:: 28293123

Free PMC Article

Similar articles

Select item 2816750521.

Acquired Resistance to the Hsp90 Inhibitor, Ganetespib, in KRAS-Mutant NSCLC Is Mediated via Reactivation of the ERK-p90RSK-mTOR Signaling Network.

Chatterjee S, Huang EH, Christie I, Kurland BF, Burns TF.

Mol Cancer Ther. 2017 May;16(5):793-804. doi: 10.1158/1535-7163.MCT-16-0677. Epub 2017 Feb 6.

PMID:: 28167505

Free PMC Article

Similar articles

Select item 2806665122.

Paradoxical functions of ZEB1 in EGFR-mutant lung cancer: tumor suppressor and driver of therapeutic resistance.

Yochum ZA, Socinski MA, Burns TF.

J Thorac Dis. 2016 Nov;8(11):E1528-E1531. doi: 10.21037/jtd.2016.11.59. No abstract available.

PMID:: 28066651

Free PMC Article

Similar articles

Select item 2737969623.

HSP90 inhibitors in lung cancer: promise still unfulfilled.

Chatterjee S, Bhattacharya S, Socinski MA, Burns TF.

Clin Adv Hematol Oncol. 2016 May;14(5):346-56. Review.

PMID:: 27379696

Similar articles

Select item 2667311924.

Near complete response after single dose of nivolumab in patient with advanced heavily pre-treated KRAS mutant pulmonary adenocarcinoma.

Davar D, Socinski MA, Dacic S, Burns TF.

Exp Hematol Oncol. 2015 Dec 14;4:34. doi: 10.1186/s40164-015-0029-7. eCollection 2015.

PMID:: 26673119

Free PMC Article

Similar articles

Select item 2666806225.

KRAS mutant lung cancer: progress thus far on an elusive therapeutic target.

Bhattacharya S, Socinski MA, Burns TF.

Clin Transl Med. 2015 Dec;4(1):35. doi: 10.1186/s40169-015-0075-0. Epub 2015 Dec 14.

PMID:: 26668062

Free PMC Article

Similar articles

Select item 2630000726.

NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function.

Sun F, Qu Z, Xiao Y, Zhou J, Burns TF, Stabile LP, Siegfried JM, Xiao G.

Oncogene. 2016 May 5;35(18):2299-310. doi: 10.1038/onc.2015.299. Epub 2015 Aug 24.

PMID:: 26300007

Free PMC Article

Similar articles

Select item 2562289627.

Structure-function studies of the bHLH phosphorylation domain of TWIST1 in prostate cancer cells.

Gajula RP, Chettiar ST, Williams RD, Nugent K, Kato Y, Wang H, Malek R, Taparra K, Cades J, Annadanam A, Yoon AR, Fertig E, Firulli BA, Mazzacurati L, Burns TF, Firulli AB, An SS, Tran PT.

Neoplasia. 2015 Jan;17(1):16-31. doi: 10.1016/j.neo.2014.10.009.

PMID:: 25622896

Free PMC Article

Similar articles

Select item 2539599228.

Targeting the estrogen pathway for the treatment and prevention of lung cancer.

Burns TF, Stabile LP.

Lung Cancer Manag. 2014 Feb 1;3(1):43-52.

PMID:: 25395992

Free PMC Article

Similar articles

Select item 2538190029.

Personalized treatment of EGFR mutant and ALK-positive patients in NSCLC.

Somasundaram A, Socinski MA, Burns TF.

Expert Opin Pharmacother. 2014 Dec;15(18):2693-708. doi: 10.1517/14656566.2014.971013. Epub 2014 Nov 10. Review.

PMID:: 25381900

Similar articles

Select item 2428298930.

Do oncogenic drivers exist in squamous cell carcinoma of the lung?

Villaruz LC, Burns TF, Socinski MA.

Oncology (Williston Park). 2013 Sep;27(9):906, 913-4. No abstract available.

PMID:: 24282989

Free PMC Article

Similar articles

Select item 2425857231.

Personalizing therapy in advanced non-small cell lung cancer.

Villaruz LC, Burns TF, Ramfidis VS, Socinski MA.

Semin Respir Crit Care Med. 2013 Dec;34(6):822-36. doi: 10.1055/s-0033-1358552. Epub 2013 Nov 20. Review.

PMID:: 24258572

Free PMC Article

Similar articles

Select item 2398221632.

The twist box domain is required for Twist1-induced prostate cancer metastasis.

Gajula RP, Chettiar ST, Williams RD, Thiyagarajan S, Kato Y, Aziz K, Wang R, Gandhi N, Wild AT, Vesuna F, Ma J, Salih T, Cades J, Fertig E, Biswal S, Burns TF, Chung CH, Rudin CM, Herman JM, Hales RK, Raman V, An SS, Tran PT.

Mol Cancer Res. 2013 Nov;11(11):1387-400. doi: 10.1158/1541-7786.MCR-13-0218-T. Epub 2013 Aug 27.

PMID:: 23982216

Free PMC Article

Similar articles

Select item 2352649133.

The prognostic and predictive value of KRAS oncogene substitutions in lung adenocarcinoma.

Villaruz LC, Socinski MA, Cunningham DE, Chiosea SI, Burns TF, Siegfried JM, Dacic S.

Cancer. 2013 Jun 15;119(12):2268-74. doi: 10.1002/cncr.28039. Epub 2013 Mar 22.

PMID:: 23526491

Free PMC Article

Similar articles

Select item 2336453234.

Inhibition of TWIST1 leads to activation of oncogene-induced senescence in oncogene-driven non-small cell lung cancer.

Burns TF, Dobromilskaya I, Murphy SC, Gajula RP, Thiyagarajan S, Chatley SN, Aziz K, Cho YJ, Tran PT, Rudin CM.

Mol Cancer Res. 2013 Apr;11(4):329-38. doi: 10.1158/1541-7786.MCR-12-0456. Epub 2013 Jan 30.

PMID:: 23364532

Free PMC Article

Similar articles

Select item 2265466735.

Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis.

Tran PT, Shroff EH, Burns TF, Thiyagarajan S, Das ST, Zabuawala T, Chen J, Cho YJ, Luong R, Tamayo P, Salih T, Aziz K, Adam SJ, Vicent S, Nielsen CH, Withofs N, Sweet-Cordero A, Gambhir SS, Rudin CM, Felsher DW.

PLoS Genet. 2012;8(5):e1002650. doi: 10.1371/journal.pgen.1002650. Epub 2012 May 24.

PMID:: 22654667

Free PMC Article

Similar articles

Select item 2218971736.

Detection of circulating tumor cells in the cerebrospinal fluid: a new frontier.

Burns TF, Wolff AC.

Cell Cycle. 2012 Jan 15;11(2):203-4. doi: 10.4161/cc.11.2.18780. Epub 2012 Jan 15. No abstract available.

PMID:: 22189717

Similar articles

Select item 2119256237.

Bevacizumab in advanced lung cancer: in search of the right drug for the right patient.

Burns TF, Juergens RA.

Oncology (Williston Park). 2010 Nov 30;24(13):1223-4, 1226. No abstract available.

PMID:: 21192562

Free Article

Similar articles

Select item 2018732138.

Lung cancer in 'never-smokers': beyond EGFR mutations and EGFR-TK inhibitors.

Burns TF, Rudin CM.

Oncology (Williston Park). 2010 Jan;24(1):48-9. Review. No abstract available.

PMID:: 20187321

Free Article

Similar articles

Select item 1710258939.

Insulin-like growth factor factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signaling.

Grimberg A, Coleman CM, Shi Z, Burns TF, MacLachlan TK, Wang W, El-Deiry WS.

Cancer Biol Ther. 2006 Oct;5(10):1408-14. Epub 2006 Oct 30.

PMID:: 17102589

Free PMC Article

Similar articles

Select item 1576999640.

p53-Dependent and p53-independent induction of insulin-like growth factor binding protein-3 by deoxyribonucleic acid damage and hypoxia.

Grimberg A, Coleman CM, Burns TF, Himelstein BP, Koch CJ, Cohen P, El-Deiry WS.

J Clin Endocrinol Metab. 2005 Jun;90(6):3568-74. Epub 2005 Mar 15.

PMID:: 15769996

Free PMC Article

Similar articles

Select item 1571365341.

DR5 knockout mice are compromised in radiation-induced apoptosis.

Finnberg N, Gruber JJ, Fei P, Rudolph D, Bric A, Kim SH, Burns TF, Ajuha H, Page R, Wu GS, Chen Y, McKenna WG, Bernhard E, Lowe S, Mak T, El-Deiry WS.

Mol Cell Biol. 2005 Mar;25(5):2000-13.