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Effects of Alcohol and Acetate on Cerebral Blood Flow: A Pilot Study.

Tanabe J, Yamamoto DJ, Sutton B, Brown MS, Hoffman PL, Burnham EL, Glueck DH, Tabakoff B.

Alcohol Clin Exp Res. 2019 Oct;43(10):2070-2078. doi: 10.1111/acer.14173. Epub 2019 Aug 24.


Unconscious bias in the selection and interpretation of data on sex and burnout - Authors' reply.

Burns KEA, Burnham EL, Dodek PM, Moss M.

Lancet Respir Med. 2019 Aug;7(8):e24. doi: 10.1016/S2213-2600(19)30223-1. Epub 2019 Jul 23. No abstract available.


Patterns of utilization and effects of hospital-specific factors on physical, occupational, and speech therapy for critically ill patients with acute respiratory failure in the USA: results of a 5-year sample.

Prohaska CC, Sottile PD, Nordon-Craft A, Gallagher MD, Burnham EL, Clark BJ, Ho M, Kiser TH, Vandivier RW, Liu W, Schenkman M, Moss M.

Crit Care. 2019 May 16;23(1):175. doi: 10.1186/s13054-019-2467-9.


Burnout in women intensivists: a hidden epidemic?

Burnham EL, Burns KEA, Moss M, Dodek PM.

Lancet Respir Med. 2019 Apr;7(4):292-294. doi: 10.1016/S2213-2600(19)30029-3. Epub 2019 Feb 8. No abstract available.


Ethics of Health Research Supported by For-Profit Cannabis Companies: What Have We Learned from Big Tobacco?

Burnham EL, Eakin MN, Pakhale S.

Ann Am Thorac Soc. 2019 Mar;16(3):396-397. doi: 10.1513/AnnalsATS.201811-764LE. No abstract available.


Impact of Macrolide Antibiotics on Hospital Readmissions and Other Clinically Important Outcomes in Critically Ill Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease: A Propensity Score-Matched Cohort Study.

Kiser TH, Reynolds PM, Moss M, Burnham EL, Ho PM, Vandivier RW; Colorado Pulmonary Outcomes Research Group (CPOR).

Pharmacotherapy. 2019 Mar;39(3):242-252. doi: 10.1002/phar.2221.


Evaluation of Prophylactic Heparin Dosage Strategies and Risk Factors for Venous Thromboembolism in the Critically Ill Patient.

Reynolds PM, Van Matre ET, Wright GC, McQueen RB, Burnham EL, Ho PJM, Moss M, Vandivier RW, Kiser TH; Colorado Pulmonary Outcomes Research Group (CPOR).

Pharmacotherapy. 2019 Mar;39(3):232-241. doi: 10.1002/phar.2212. Epub 2019 Jan 21.


The authors reply.

Kiser TH, Burnham EL, Clark B, Ho PM, Allen RR, Moss M, Vandivier RW.

Crit Care Med. 2018 Dec;46(12):e1224-e1225. doi: 10.1097/CCM.0000000000003453. No abstract available.


Alcohol and cannabis use alter pulmonary innate immunity.

Bailey KL, Wyatt TA, Katafiasz DM, Taylor KW, Heires AJ, Sisson JH, Romberger DJ, Burnham EL.

Alcohol. 2019 Nov;80:131-138. doi: 10.1016/j.alcohol.2018.11.002. Epub 2018 Nov 10.


Evaluation of unfractionated heparin versus low-molecular-weight heparin and fondaparinux for pharmacologic venous thromboembolic prophylaxis in critically ill patients with cancer.

Van Matre ET, Reynolds PM, MacLaren R, Mueller SW, Wright GC, Moss M, Burnham EL, Ho PM, Vandivier RW, Kiser TH.

J Thromb Haemost. 2018 Dec;16(12):2492-2500. doi: 10.1111/jth.14317. Epub 2018 Nov 15.


The impact of alcohol use disorders on pulmonary immune cell inflammatory responses to Streptococcus pneumoniae.

Gaydos J, McNally A, Burnham EL.

Alcohol. 2019 Nov;80:119-130. doi: 10.1016/j.alcohol.2018.08.016. Epub 2018 Sep 5.


Optimal Cut-Points for Phosphatidylethanol Vary by Clinical Setting: Response to Nguyen and Seth's (2018) Letter to the Editor.

Afshar M, Burnham EL, Joyce C, Kovacs EJ, Lowery EM.

Alcohol Clin Exp Res. 2018 Oct;42(10):2064-2065. doi: 10.1111/acer.13853. Epub 2018 Aug 13. No abstract available.


Half-Dose Versus Full-Dose Alteplase for Treatment of Pulmonary Embolism.

Kiser TH, Burnham EL, Clark B, Ho PM, Allen RR, Moss M, Vandivier RW.

Crit Care Med. 2018 Oct;46(10):1617-1625. doi: 10.1097/CCM.0000000000003288.


Injury Characteristics and von Willebrand Factor for the Prediction of Acute Respiratory Distress Syndrome in Patients With Burn Injury: Development and Internal Validation.

Afshar M, Burnham EL, Joyce C, Gagnon R, Dunn R, Albright JM, Ramirez L, Repine JE, Netzer G, Kovacs EJ.

Ann Surg. 2019 Dec;270(6):1186-1193. doi: 10.1097/SLA.0000000000002795.


The authors reply.

Kelmenson DA, Held N, Allen RR, Quan D, Burnham EL, Clark BJ, Ho PM, Kiser TH, Vandivier RW, Moss M.

Crit Care Med. 2018 Apr;46(4):e347-e348. doi: 10.1097/CCM.0000000000002984. No abstract available.


An Observational Study of the Efficacy of Cisatracurium Compared with Vecuronium in Patients with or at Risk for Acute Respiratory Distress Syndrome.

Sottile PD, Kiser TH, Burnham EL, Ho PM, Allen RR, Vandivier RW, Moss M; Colorado Pulmonary Outcomes Research Group (CPOR).

Am J Respir Crit Care Med. 2018 Apr 1;197(7):897-904. doi: 10.1164/rccm.201706-1132OC.


Age-related immune responses after burn and inhalation injury are associated with altered clinical outcomes.

Frankel JH, Boe DM, Albright JM, O'Halloran EB, Carter SR, Davis CS, Ramirez L, Burnham EL, Gamelli RL, Afshar M, Kovacs EJ.

Exp Gerontol. 2018 May;105:78-86. doi: 10.1016/j.exger.2017.10.022. Epub 2017 Oct 26.


Outcomes of ICU Patients With a Discharge Diagnosis of Critical Illness Polyneuromyopathy: A Propensity-Matched Analysis.

Kelmenson DA, Held N, Allen RR, Quan D, Burnham EL, Clark BJ, Ho PM, Kiser TH, Vandivier RW, Moss M.

Crit Care Med. 2017 Dec;45(12):2055-2060. doi: 10.1097/CCM.0000000000002763.


Malondialdehyde-Acetaldehyde (MAA) Protein Adducts Are Found Exclusively in the Lungs of Smokers with Alcohol Use Disorders and Are Associated with Systemic Anti-MAA Antibodies.

Sapkota M, Burnham EL, DeVasure JM, Sweeter JM, Hunter CD, Duryee MJ, Klassen LW, Kharbanda KK, Sisson JH, Thiele GM, Wyatt TA.

Alcohol Clin Exp Res. 2017 Dec;41(12):2093-2099. doi: 10.1111/acer.13509. Epub 2017 Nov 4.


Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice.

Neudecker V, Brodsky KS, Clambey ET, Schmidt EP, Packard TA, Davenport B, Standiford TJ, Weng T, Fletcher AA, Barthel L, Masterson JC, Furuta GT, Cai C, Blackburn MR, Ginde AA, Graner MW, Janssen WJ, Zemans RL, Evans CM, Burnham EL, Homann D, Moss M, Kreth S, Zacharowski K, Henson PM, Eltzschig HK.

Sci Transl Med. 2017 Sep 20;9(408). pii: eaah5360. doi: 10.1126/scitranslmed.aah5360.


The Contributing Risk of Tobacco Use for ARDS Development in Burn-Injured Adults With Inhalation Injury.

Afshar M, Netzer G, Mosier MJ, Cooper RS, Adams W, Burnham EL, Kovacs EJ, Durazo-Arvizu R, Kliethermes S.

Respir Care. 2017 Nov;62(11):1456-1465. doi: 10.4187/respcare.05560. Epub 2017 Sep 12.


The respiratory tract microbial biogeography in alcohol use disorder.

Samuelson DR, Burnham EL, Maffei VJ, Vandivier RW, Blanchard EE, Shellito JE, Luo M, Taylor CM, Welsh DA.

Am J Physiol Lung Cell Mol Physiol. 2018 Jan 1;314(1):L107-L117. doi: 10.1152/ajplung.00277.2017. Epub 2017 Aug 31.


Alcohol abuse is associated with enhanced pulmonary and systemic xanthine oxidoreductase activity.

Fini MA, Gaydos J, McNally A, Karoor V, Burnham EL.

Am J Physiol Lung Cell Mol Physiol. 2017 Dec 1;313(6):L1047-L1057. doi: 10.1152/ajplung.00570.2016. Epub 2017 Aug 24.


Impact of Regular Cannabis Use on Biomarkers of Lower Urinary Tract Function.

Nedumaran B, Rudra P, Gaydos J, Kumar S, Meacham RB, Burnham EL, Malykhina AP.

Urology. 2017 Nov;109:223.e9-223.e16. doi: 10.1016/j.urology.2017.08.011. Epub 2017 Aug 18.


Cut-Point Levels of Phosphatidylethanol to Identify Alcohol Misuse in a Mixed Cohort Including Critically Ill Patients.

Afshar M, Burnham EL, Joyce C, Clark BJ, Yong M, Gaydos J, Cooper RS, Smith GS, Kovacs EJ, Lowery EM.

Alcohol Clin Exp Res. 2017 Oct;41(10):1745-1753. doi: 10.1111/acer.13471. Epub 2017 Sep 13.


Alternative pre-mRNA splicing of Toll-like receptor signaling components in peripheral blood mononuclear cells from patients with ARDS.

Blumhagen RZ, Hedin BR, Malcolm KC, Burnham EL, Moss M, Abraham E, Huie TJ, Nick JA, Fingerlin TE, Alper S.

Am J Physiol Lung Cell Mol Physiol. 2017 Nov 1;313(5):L930-L939. doi: 10.1152/ajplung.00247.2017. Epub 2017 Aug 3.


The Experience of Patients with Alcohol Misuse after Surviving a Critical Illness. A Qualitative Study.

Clark BJ, Jones J, Reed KD, Hodapp R, Douglas IS, Van Pelt D, Burnham EL, Moss M.

Ann Am Thorac Soc. 2017 Jul;14(7):1154-1161. doi: 10.1513/AnnalsATS.201611-854OC.


Gender Parity in Critical Care Medicine.

Mehta S, Burns KEA, Machado FR, Fox-Robichaud AE, Cook DJ, Calfee CS, Ware LB, Burnham EL, Kissoon N, Marshall JC, Mancebo J, Finfer S, Hartog C, Reinhart K, Maitland K, Stapleton RD, Kwizera A, Amin P, Abroug F, Smith O, Laake JH, Shrestha GS, Herridge MS.

Am J Respir Crit Care Med. 2017 Aug 15;196(4):425-429. doi: 10.1164/rccm.201701-0076CP. Review.


Activation of NLRP3 inflammasome by cholesterol crystals in alcohol consumption induces atherosclerotic lesions.

Abdul-Muneer PM, Alikunju S, Mishra V, Schuetz H, Szlachetka AM, Burnham EL, Haorah J.

Brain Behav Immun. 2017 May;62:291-305. doi: 10.1016/j.bbi.2017.02.014. Epub 2017 Feb 21.


Adjuvant Therapies for ARDS: Not Ready for Prime Time?

Aschner Y, Burnham EL.

Ann Am Thorac Soc. 2017 Jan;14(1):14-16. doi: 10.1513/AnnalsATS.201610-809ED. No abstract available.


Alcohol and lung injury and immunity.

Yeligar SM, Chen MM, Kovacs EJ, Sisson JH, Burnham EL, Brown LA.

Alcohol. 2016 Sep;55:51-59. doi: 10.1016/j.alcohol.2016.08.005. Epub 2016 Sep 16. Review.


The Relationship Between Airway Antioxidant Levels, Alcohol Use Disorders, and Cigarette Smoking.

Burnham EL, McNally A, Gaydos J, Brown LA.

Alcohol Clin Exp Res. 2016 Oct;40(10):2147-2160. doi: 10.1111/acer.13201. Epub 2016 Sep 14.


Extremes of Interferon-Stimulated Gene Expression Associate with Worse Outcomes in the Acute Respiratory Distress Syndrome.

Nick JA, Caceres SM, Kret JE, Poch KR, Strand M, Faino AV, Nichols DP, Saavedra MT, Taylor-Cousar JL, Geraci MW, Burnham EL, Fessler MB, Suratt BT, Abraham E, Moss M, Malcolm KC.

PLoS One. 2016 Sep 8;11(9):e0162490. doi: 10.1371/journal.pone.0162490. eCollection 2016.


Alcohol and inflammatory responses: Highlights of the 2015 Alcohol and Immunology Research Interest Group (AIRIG) meeting.

Cannon AR, Morris NL, Hammer AM, Curtis B, Remick DG, Yeligar SM, Poole L, Burnham EL, Wyatt TA, Molina PE, So-Armah K, Cisneros T, Wang G, Lang CH, Mandrekar P, Kovacs EJ, Choudhry MA.

Alcohol. 2016 Aug;54:73-7. doi: 10.1016/j.alcohol.2016.06.005. Epub 2016 Jul 25.


Composition of the Sepsis Definitions Task Force.

Burnham EL, Roman J.

JAMA. 2016 Jul 26;316(4):460-1. doi: 10.1001/jama.2016.6383. No abstract available.


Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation.

Moazed F, Burnham EL, Vandivier RW, O'Kane CM, Shyamsundar M, Hamid U, Abbott J, Thickett DR, Matthay MA, McAuley DF, Calfee CS.

Thorax. 2016 Dec;71(12):1130-1136. doi: 10.1136/thoraxjnl-2015-207886. Epub 2016 Feb 2.


Azithromycin use and outcomes in severe sepsis patients with and without pneumonia.

Afshar M, Foster CL, Layden JE, Burnham EL.

J Crit Care. 2016 Apr;32:120-5. doi: 10.1016/j.jcrc.2015.12.010. Epub 2015 Dec 21.


Alveolar macrophage inflammatory mediator expression is elevated in the setting of alcohol use disorders.

O'Halloran EB, Curtis BJ, Afshar M, Chen MM, Kovacs EJ, Burnham EL.

Alcohol. 2016 Feb;50:43-50. doi: 10.1016/j.alcohol.2015.11.003. Epub 2015 Nov 24.


Alcohol abuse and smoking alter inflammatory mediator production by pulmonary and systemic immune cells.

Gaydos J, McNally A, Guo R, Vandivier RW, Simonian PL, Burnham EL.

Am J Physiol Lung Cell Mol Physiol. 2016 Mar 15;310(6):L507-18. doi: 10.1152/ajplung.00242.2015. Epub 2016 Jan 8.


γδ T cells protect against LPS-induced lung injury.

Wehrmann F, Lavelle JC, Collins CB, Tinega AN, Thurman JM, Burnham EL, Simonian PL.

J Leukoc Biol. 2016 Feb;99(2):373-86. doi: 10.1189/jlb.4A0115-017RR. Epub 2015 Oct 1.


TLR2 and TLR4 Expression and Inflammatory Cytokines are Altered in the Airway Epithelium of Those with Alcohol Use Disorders.

Bailey KL, Romberger DJ, Katafiasz DM, Heires AJ, Sisson JH, Wyatt TA, Burnham EL.

Alcohol Clin Exp Res. 2015 Sep;39(9):1691-7. doi: 10.1111/acer.12803. Epub 2015 Jul 24.


Metabolic Consequences of Chronic Alcohol Abuse in Non-Smokers: A Pilot Study.

Obianyo O, Liang Y, Burnham EL, Mehta A, Park Y, Uppal K, Harris FL, Jones DP, Brown LA.

PLoS One. 2015 Jun 23;10(6):e0129570. doi: 10.1371/journal.pone.0129570. eCollection 2015.


Cannabis Smoking in 2015: A Concern for Lung Health?

Biehl JR, Burnham EL.

Chest. 2015 Sep;148(3):596-606. doi: 10.1378/chest.15-0447. Review.


Introduction to the 57th annual Thomas L. Petty Aspen Lung Conference: Rebuilding the injured lung.

Riches DW, Burnham EL, Moss M, Downey GP, Schmidt EP.

Ann Am Thorac Soc. 2015 Mar;12 Suppl 1:S1-2. doi: 10.1513/AnnalsATS.201411-536MG. No abstract available.


Detection of fibroproliferation by chest high-resolution CT scan in resolving ARDS.

Burnham EL, Hyzy RC, Paine R 3rd, Kelly AM, Quint LE, Lynch D, Curran-Everett D, Moss M, Standiford TJ.

Chest. 2014 Nov;146(5):1196-1204. doi: 10.1378/chest.13-2708.


Training mentors of clinical and translational research scholars: a randomized controlled trial.

Pfund C, House SC, Asquith P, Fleming MF, Buhr KA, Burnham EL, Eichenberger Gilmore JM, Huskins WC, McGee R, Schurr K, Shapiro ED, Spencer KC, Sorkness CA.

Acad Med. 2014 May;89(5):774-82. doi: 10.1097/ACM.0000000000000218.


Neuroendocrine signaling via the serotonin transporter regulates clearance of apoptotic cells.

Tanaka T, Doe JM, Horstmann SA, Ahmad S, Ahmad A, Min SJ, Reynolds PR, Suram S, Gaydos J, Burnham EL, Vandivier RW.

J Biol Chem. 2014 Apr 11;289(15):10466-75. doi: 10.1074/jbc.M113.482299. Epub 2014 Feb 25.


24/7 attendings: "helicoptering" the housestaff?

Burnham EL.

Pediatrics. 2014 Jan;133(1):131-3. doi: 10.1542/peds.2013-3493. Epub 2013 Dec 9. No abstract available.


Surrogate consent for genetic testing, the reconsent process, and consent for long-term outcomes in acute respiratory distress syndrome trials.

Smart A, Thompson BT, Needham DM, Hopkins RO, Williams A, Burnham EL, Moss M; NHLBI ARDS Network Investigators.

Am J Respir Crit Care Med. 2013 Dec 1;188(11):1370-3. doi: 10.1164/rccm.201307-1235LE. No abstract available.


Post-extubation dysphagia is associated with longer hospitalization in survivors of critical illness with neurologic impairment.

Macht M, King CJ, Wimbish T, Clark BJ, Benson AB, Burnham EL, Williams A, Moss M.

Crit Care. 2013 Jun 20;17(3):R119. doi: 10.1186/cc12791.

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