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Items: 1 to 50 of 74

1.

Radiation-induced DNA damage cooperates with heterozygosity of TP53 and PTEN to generate high grade gliomas.

Todorova PK, Fletcher-Sananikone E, Mukherjee B, Kollipara R, Vemireddy V, Xie XJ, Guida PM, Story MD, Hatanpaa K, Habib AA, Kittler R, Bachoo R, Hromas R, Floyd JR, Burma S.

Cancer Res. 2019 May 14. pii: canres.0680.2019. doi: 10.1158/0008-5472.CAN-19-0680. [Epub ahead of print]

PMID:
31088835
2.

TNF-driven adaptive response mediates resistance to EGFR inhibition in lung cancer.

Gong K, Guo G, Gerber DE, Gao B, Peyton M, Huang C, Minna JD, Hatanpaa KJ, Kernstine K, Cai L, Xie Y, Zhu H, Fattah FJ, Zhang S, Takahashi M, Mukherjee B, Burma S, Dowell J, Dao K, Papadimitrakopoulou VA, Olivas V, Bivona TG, Zhao D, Habib AA.

J Clin Invest. 2018 Jun 1;128(6):2500-2518. doi: 10.1172/JCI96148. Epub 2018 May 7.

3.

BRD4 Promotes DNA Repair and Mediates the Formation of TMPRSS2-ERG Gene Rearrangements in Prostate Cancer.

Li X, Baek G, Ramanand SG, Sharp A, Gao Y, Yuan W, Welti J, Rodrigues DN, Dolling D, Figueiredo I, Sumanasuriya S, Crespo M, Aslam A, Li R, Yin Y, Mukherjee B, Kanchwala M, Hughes AM, Halsey WS, Chiang CM, Xing C, Raj GV, Burma S, de Bono J, Mani RS.

Cell Rep. 2018 Jan 16;22(3):796-808. doi: 10.1016/j.celrep.2017.12.078.

4.

EGFR Mutations Compromise Hypoxia-Associated Radiation Resistance through Impaired Replication Fork-Associated DNA Damage Repair.

Saki M, Makino H, Javvadi P, Tomimatsu N, Ding LH, Clark JE, Gavin E, Takeda K, Andrews J, Saha D, Story MD, Burma S, Nirodi CS.

Mol Cancer Res. 2017 Nov;15(11):1503-1516. doi: 10.1158/1541-7786.MCR-17-0136. Epub 2017 Aug 11.

5.

Androgen Receptor Variants Mediate DNA Repair after Prostate Cancer Irradiation.

Yin Y, Li R, Xu K, Ding S, Li J, Baek G, Ramanand SG, Ding S, Liu Z, Gao Y, Kanchwala MS, Li X, Hutchinson R, Liu X, Woldu SL, Xing C, Desai NB, Feng FY, Burma S, de Bono JS, Dehm SM, Mani RS, Chen BPC, Raj GV.

Cancer Res. 2017 Sep 15;77(18):4745-4754. doi: 10.1158/0008-5472.CAN-17-0164. Epub 2017 Jul 28.

6.

A TNF-JNK-Axl-ERK signaling axis mediates primary resistance to EGFR inhibition in glioblastoma.

Guo G, Gong K, Ali S, Ali N, Shallwani S, Hatanpaa KJ, Pan E, Mickey B, Burma S, Wang DH, Kesari S, Sarkaria JN, Zhao D, Habib AA.

Nat Neurosci. 2017 Aug;20(8):1074-1084. doi: 10.1038/nn.4584. Epub 2017 Jun 12.

7.

DNA-damage-induced degradation of EXO1 exonuclease limits DNA end resection to ensure accurate DNA repair.

Tomimatsu N, Mukherjee B, Harris JL, Boffo FL, Hardebeck MC, Potts PR, Khanna KK, Burma S.

J Biol Chem. 2017 Jun 30;292(26):10779-10790. doi: 10.1074/jbc.M116.772475. Epub 2017 May 17.

8.

Prevalence of female genital tuberculosis, its risk factors and associated clinical features among the women of Andaman Islands, India: a community-based study.

Parvez R, Sugunan AP, Vijayachari P, Burma SP, Mandal A, Saha MK, Shah WA.

Public Health. 2017 Jul;148:56-62. doi: 10.1016/j.puhe.2017.03.001. Epub 2017 Apr 8.

PMID:
28404534
9.

MET signaling promotes DNA repair and radiation resistance in glioblastoma stem-like cells.

Todorova PK, Mukherjee B, Burma S.

Ann Transl Med. 2017 Feb;5(3):61. doi: 10.21037/atm.2017.01.67. No abstract available.

10.

Enhanced dependency of KRAS-mutant colorectal cancer cells on RAD51-dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae.

Kalimutho M, Bain AL, Mukherjee B, Nag P, Nanayakkara DM, Harten SK, Harris JL, Subramanian GN, Sinha D, Shirasawa S, Srihari S, Burma S, Khanna KK.

Mol Oncol. 2017 May;11(5):470-490. doi: 10.1002/1878-0261.12040. Epub 2017 Mar 27.

11.

Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks.

Kim HS, Nickoloff JA, Wu Y, Williamson EA, Sidhu GS, Reinert BL, Jaiswal AS, Srinivasan G, Patel B, Kong K, Burma S, Lee SH, Hromas RA.

J Biol Chem. 2017 Feb 17;292(7):2795-2804. doi: 10.1074/jbc.M116.758235. Epub 2017 Jan 3.

12.

INT6/EIF3E Controls the RNF8-Dependent Ubiquitylation Pathway and Facilitates DNA Double-Strand Break Repair in Human Cells.

Morris C, Tomimatsu N, Burma S, Jalinot P.

Cancer Res. 2016 Oct 15;76(20):6054-6065. Epub 2016 Aug 22.

13.

Augmented HR Repair Mediates Acquired Temozolomide Resistance in Glioblastoma.

Gil Del Alcazar CR, Todorova PK, Habib AA, Mukherjee B, Burma S.

Mol Cancer Res. 2016 Oct;14(10):928-940. Epub 2016 Jun 29.

14.

Mouse models of radiation-induced glioblastoma.

Mukherjee B, Todorova PK, Burma S.

Oncoscience. 2015 Dec 28;2(12):934-5. eCollection 2015. No abstract available.

15.

EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.

Wu Y, Lee SH, Williamson EA, Reinert BL, Cho JH, Xia F, Jaiswal AS, Srinivasan G, Patel B, Brantley A, Zhou D, Shao L, Pathak R, Hauer-Jensen M, Singh S, Kong K, Wu X, Kim HS, Beissbarth T, Gaedcke J, Burma S, Nickoloff JA, Hromas RA.

PLoS Genet. 2015 Dec 18;11(12):e1005675. doi: 10.1371/journal.pgen.1005675. eCollection 2015 Dec.

16.

Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone.

Chakrabarti G, Silvers MA, Ilcheva M, Liu Y, Moore ZR, Luo X, Gao J, Anderson G, Liu L, Sarode V, Gerber DE, Burma S, DeBerardinis RJ, Gerson SL, Boothman DA.

Sci Rep. 2015 Nov 25;5:17066. doi: 10.1038/srep17066.

17.

Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone.

Chakrabarti G, Moore ZR, Luo X, Ilcheva M, Ali A, Padanad M, Zhou Y, Xie Y, Burma S, Scaglioni PP, Cantley LC, DeBerardinis RJ, Kimmelman AC, Lyssiotis CA, Boothman DA.

Cancer Metab. 2015 Oct 12;3:12. doi: 10.1186/s40170-015-0137-1. eCollection 2015.

18.

Concepts and challenges in cancer risk prediction for the space radiation environment.

Barcellos-Hoff MH, Blakely EA, Burma S, Fornace AJ Jr, Gerson S, Hlatky L, Kirsch DG, Luderer U, Shay J, Wang Y, Weil MM.

Life Sci Space Res (Amst). 2015 Jul;6:92-103. doi: 10.1016/j.lssr.2015.07.006. Epub 2015 Jul 17. Review.

19.
20.

Immunofluorescence-based methods to monitor DNA end resection.

Mukherjee B, Tomimatsu N, Burma S.

Methods Mol Biol. 2015;1292:67-75. doi: 10.1007/978-1-4939-2522-3_5.

21.

Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice.

Tomimatsu N, Mukherjee B, Catherine Hardebeck M, Ilcheva M, Vanessa Camacho C, Louise Harris J, Porteus M, Llorente B, Khanna KK, Burma S.

Nat Commun. 2014 Apr 7;5:3561. doi: 10.1038/ncomms4561.

22.

DNA double-strand breaks cooperate with loss of Ink4 and Arf tumor suppressors to generate glioblastomas with frequent Met amplification.

Camacho CV, Todorova PK, Hardebeck MC, Tomimatsu N, Gil del Alcazar CR, Ilcheva M, Mukherjee B, McEllin B, Vemireddy V, Hatanpaa K, Story MD, Habib AA, Murty VV, Bachoo R, Burma S.

Oncogene. 2015 Feb 19;34(8):1064-72. doi: 10.1038/onc.2014.29. Epub 2014 Mar 17.

23.

Primary skull lymphoma: A case report and review of similar cases.

Senapati SB, Mishra SS, Dhir MK, Das S, Burma S.

South Asian J Cancer. 2013 Oct;2(4):287. doi: 10.4103/2278-330X.119908. No abstract available.

24.

Inhibition of DNA double-strand break repair by the dual PI3K/mTOR inhibitor NVP-BEZ235 as a strategy for radiosensitization of glioblastoma.

Gil del Alcazar CR, Hardebeck MC, Mukherjee B, Tomimatsu N, Gao X, Yan J, Xie XJ, Bachoo R, Li L, Habib AA, Burma S.

Clin Cancer Res. 2014 Mar 1;20(5):1235-48. doi: 10.1158/1078-0432.CCR-13-1607. Epub 2013 Dec 23.

25.

EGFR wild type antagonizes EGFRvIII-mediated activation of Met in glioblastoma.

Li L, Puliyappadamba VT, Chakraborty S, Rehman A, Vemireddy V, Saha D, Souza RF, Hatanpaa KJ, Koduru P, Burma S, Boothman DA, Habib AA.

Oncogene. 2015 Jan 2;34(1):129-134. doi: 10.1038/onc.2013.534. Epub 2013 Dec 23.

26.

An EGFR wild type-EGFRvIII-HB-EGF feed-forward loop regulates the activation of EGFRvIII.

Li L, Chakraborty S, Yang CR, Hatanpaa KJ, Cipher DJ, Puliyappadamba VT, Rehman A, Jiwani AJ, Mickey B, Madden C, Raisanen J, Burma S, Saha D, Wang Z, Pingle SC, Kesari S, Boothman DA, Habib AA.

Oncogene. 2014 Aug 14;33(33):4253-64. doi: 10.1038/onc.2013.400. Epub 2013 Sep 30.

27.

Opposing effect of EGFRWT on EGFRvIII-mediated NF-κB activation with RIP1 as a cell death switch.

Puliyappadamba VT, Chakraborty S, Chauncey SS, Li L, Hatanpaa KJ, Mickey B, Noorani S, Shu HK, Burma S, Boothman DA, Habib AA.

Cell Rep. 2013 Aug 29;4(4):764-75. doi: 10.1016/j.celrep.2013.07.025. Epub 2013 Aug 22.

28.

Cytoplasmic TRADD confers a worse prognosis in glioblastoma.

Chakraborty S, Li L, Tang H, Xie Y, Puliyappadamba VT, Raisanen J, Burma S, Boothman DA, Cochran B, Wu J, Habib AA.

Neoplasia. 2013 Aug;15(8):888-97.

29.

A case of primary skull lymphoma: review of literature.

Mishra SS, Senapati SB, Dhir MK, Das S, Burma S.

Neurol India. 2013 May-Jun;61(3):334-6. doi: 10.4103/0028-3886.115101. Review. No abstract available.

30.

Primary intraosseous malignant peripheral nerve sheath tumor of spine with a giant paraspinal and retrospinal subcutaneous extension.

Patnaik A, Mishra SS, Senapati SB, Patra SK, Tripathy K, Burma S.

Surg Neurol Int. 2012;3:157. doi: 10.4103/2152-7806.105096. Epub 2012 Dec 26.

31.

Nucleolin participates in DNA double-strand break-induced damage response through MDC1-dependent pathway.

Kobayashi J, Fujimoto H, Sato J, Hayashi I, Burma S, Matsuura S, Chen DJ, Komatsu K.

PLoS One. 2012;7(11):e49245. doi: 10.1371/journal.pone.0049245. Epub 2012 Nov 7.

32.

The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection.

Costelloe T, Louge R, Tomimatsu N, Mukherjee B, Martini E, Khadaroo B, Dubois K, Wiegant WW, Thierry A, Burma S, van Attikum H, Llorente B.

Nature. 2012 Sep 27;489(7417):581-4. doi: 10.1038/nature11353. Epub 2012 Sep 9.

33.

AZD5438, an inhibitor of Cdk1, 2, and 9, enhances the radiosensitivity of non-small cell lung carcinoma cells.

Raghavan P, Tumati V, Yu L, Chan N, Tomimatsu N, Burma S, Bristow RG, Saha D.

Int J Radiat Oncol Biol Phys. 2012 Nov 15;84(4):e507-14. doi: 10.1016/j.ijrobp.2012.05.035. Epub 2012 Jul 12.

34.

INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells.

Morris C, Tomimatsu N, Richard DJ, Cluet D, Burma S, Khanna KK, Jalinot P.

Cancer Res. 2012 Apr 15;72(8):2006-16. doi: 10.1158/0008-5472.CAN-11-2562.

35.

The dual PI3K/mTOR inhibitor NVP-BEZ235 is a potent inhibitor of ATM- and DNA-PKCs-mediated DNA damage responses.

Mukherjee B, Tomimatsu N, Amancherla K, Camacho CV, Pichamoorthy N, Burma S.

Neoplasia. 2012 Jan;14(1):34-43.

36.

Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions.

Tomimatsu N, Mukherjee B, Deland K, Kurimasa A, Bolderson E, Khanna KK, Burma S.

DNA Repair (Amst). 2012 Apr 1;11(4):441-8. doi: 10.1016/j.dnarep.2012.01.006. Epub 2012 Feb 11.

37.

DNA double-strand breaks make bedfellows of ATM and AKT.

Mukherjee B, Burma S.

Cell Cycle. 2011 Oct 1;10(19):3230. doi: 10.4161/cc.10.19.17080. Epub 2011 Oct 1. No abstract available.

PMID:
21946524
38.

Epothilone B confers radiation dose enhancement in DAB2IP gene knock-down radioresistant prostate cancer cells.

Kong Z, Raghavan P, Xie D, Boike T, Burma S, Chen D, Chakraborty A, Hsieh JT, Saha D.

Int J Radiat Oncol Biol Phys. 2010 Nov 15;78(4):1210-8. doi: 10.1016/j.ijrobp.2010.06.019.

PMID:
20970033
39.

Targeting nonhomologous end-joining through epidermal growth factor receptor inhibition: rationale and strategies for radiosensitization.

Mukherjee B, Choy H, Nirodi C, Burma S.

Semin Radiat Oncol. 2010 Oct;20(4):250-7. doi: 10.1016/j.semradonc.2010.05.002. Review.

40.

Epidermal growth factor receptor in glioma: signal transduction, neuropathology, imaging, and radioresistance.

Hatanpaa KJ, Burma S, Zhao D, Habib AA.

Neoplasia. 2010 Sep;12(9):675-84. Review.

41.

Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks.

Camacho CV, Mukherjee B, McEllin B, Ding LH, Hu B, Habib AA, Xie XJ, Nirodi CS, Saha D, Story MD, Balajee AS, Bachoo RM, Boothman DA, Burma S.

Carcinogenesis. 2010 Oct;31(10):1889-96. doi: 10.1093/carcin/bgq153. Epub 2010 Jul 26.

42.

WRN participates in translesion synthesis pathway through interaction with NBS1.

Kobayashi J, Okui M, Asaithamby A, Burma S, Chen BP, Tanimoto K, Matsuura S, Komatsu K, Chen DJ.

Mech Ageing Dev. 2010 Jun;131(6):436-44. doi: 10.1016/j.mad.2010.06.005. Epub 2010 Jun 17.

43.

PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors.

McEllin B, Camacho CV, Mukherjee B, Hahm B, Tomimatsu N, Bachoo RM, Burma S.

Cancer Res. 2010 Jul 1;70(13):5457-64. doi: 10.1158/0008-5472.CAN-09-4295. Epub 2010 Jun 8.

44.

Downregulation of human DAB2IP gene expression in prostate cancer cells results in resistance to ionizing radiation.

Kong Z, Xie D, Boike T, Raghavan P, Burma S, Chen DJ, Habib AA, Chakraborty A, Hsieh JT, Saha D.

Cancer Res. 2010 Apr 1;70(7):2829-39. doi: 10.1158/0008-5472.CAN-09-2919. Epub 2010 Mar 23.

45.

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks.

Bolderson E, Tomimatsu N, Richard DJ, Boucher D, Kumar R, Pandita TK, Burma S, Khanna KK.

Nucleic Acids Res. 2010 Apr;38(6):1821-31. doi: 10.1093/nar/gkp1164. Epub 2009 Dec 17.

46.

Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells.

Tomimatsu N, Mukherjee B, Burma S.

EMBO Rep. 2009 Jun;10(6):629-35. doi: 10.1038/embor.2009.60. Epub 2009 May 15.

47.

EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma.

Mukherjee B, McEllin B, Camacho CV, Tomimatsu N, Sirasanagandala S, Nannepaga S, Hatanpaa KJ, Mickey B, Madden C, Maher E, Boothman DA, Furnari F, Cavenee WK, Bachoo RM, Burma S.

Cancer Res. 2009 May 15;69(10):4252-9. doi: 10.1158/0008-5472.CAN-08-4853. Epub 2009 May 12.

48.

RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN.

Park S, Zhao D, Hatanpaa KJ, Mickey BE, Saha D, Boothman DA, Story MD, Wong ET, Burma S, Georgescu MM, Rangnekar VM, Chauncey SS, Habib AA.

Cancer Res. 2009 May 15;69(10):4107-11. doi: 10.1158/0008-5472.CAN-09-0474. Epub 2009 May 12.

49.

Histone H2AX participates the DNA damage-induced ATM activation through interaction with NBS1.

Kobayashi J, Tauchi H, Chen B, Burma S, Tashiro S, Matsuura S, Tanimoto K, Chen DJ, Komatsu K.

Biochem Biophys Res Commun. 2009 Mar 20;380(4):752-7. doi: 10.1016/j.bbrc.2009.01.109. Epub 2009 Jan 23. Erratum in: Biochem Biophys Res Commun. 2009 Jun 26;384(2):271. Bruma, Sandeep [corrected to Burma, Sandeep].

PMID:
19338747
50.

Modulation of the DNA-damage response to HZE particles by shielding.

Mukherjee B, Camacho CV, Tomimatsu N, Miller J, Burma S.

DNA Repair (Amst). 2008 Oct 1;7(10):1717-30. doi: 10.1016/j.dnarep.2008.06.016. Epub 2008 Aug 13.

PMID:
18672098

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