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Early safety of tenofovir alafenamide in patients with a history of tubulopathy on tenofovir disoproxil fumarate: a randomized controlled clinical trial.

Hamzah L, Williams D, Bailey AC, Jones R, Ibrahim F, Musso CG, Burling K, Barbini B, Campbell L, Post FA; Fanconi-Tenofovir Alafenamide trial team.

HIV Med. 2019 Nov 3. doi: 10.1111/hiv.12819. [Epub ahead of print]


A New Estimate of the Glomerular Sieving Coefficient for Retinol-Binding Protein 4 Suggests It Is Not Freely Filtered.

Norden AGW, Burling KA, Zeni L, Unwin RJ.

Kidney Int Rep. 2019 Apr 29;4(7):1017-1018. doi: 10.1016/j.ekir.2019.04.017. eCollection 2019 Jul. No abstract available.


Associations of vomiting and antiemetic use in pregnancy with levels of circulating GDF15 early in the second trimester: A nested case-control study.

Petry CJ, Ong KK, Burling KA, Barker P, Goodburn SF, Perry JRB, Acerini CL, Hughes IA, Painter RC, Afink GB, Dunger DB, O'Rahilly S.

Wellcome Open Res. 2018 Sep 21;3:123. doi: 10.12688/wellcomeopenres.14818.1. eCollection 2018.


Low-dose interleukin-2 in patients with stable ischaemic heart disease and acute coronary syndromes (LILACS): protocol and study rationale for a randomised, double-blind, placebo-controlled, phase I/II clinical trial.

Zhao TX, Kostapanos M, Griffiths C, Arbon EL, Hubsch A, Kaloyirou F, Helmy J, Hoole SP, Rudd JHF, Wood G, Burling K, Bond S, Cheriyan J, Mallat Z.

BMJ Open. 2018 Sep 17;8(9):e022452. doi: 10.1136/bmjopen-2018-022452.


Assessment and Management of Anti-Insulin Autoantibodies in Varying Presentations of Insulin Autoimmune Syndrome.

Church D, Cardoso L, Kay RG, Williams CL, Freudenthal B, Clarke C, Harris J, Moorthy M, Karra E, Gribble FM, Reimann F, Burling K, Williams AJK, Munir A, Jones TH, Führer D, Moeller LC, Cohen M, Khoo B, Halsall D, Semple RK.

J Clin Endocrinol Metab. 2018 Oct 1;103(10):3845-3855. doi: 10.1210/jc.2018-00972.


The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus.

Oliveira JJ, Karrar S, Rainbow DB, Pinder CL, Clarke P, Rubio García A, Al-Assar O, Burling K, Morris S, Stratton R, Vyse TJ, Wicker LS, Todd JA, Ferreira RC.

Arthritis Res Ther. 2018 Jul 27;20(1):152. doi: 10.1186/s13075-018-1649-1.


Frequent Monitoring of C-Peptide Levels in Newly Diagnosed Type 1 Subjects Using Dried Blood Spots Collected at Home.

Willemsen RH, Burling K, Barker P, Ackland F, Dias RP, Edge J, Smith A, Todd J, Lopez B, Mander AP, Guy C, Dunger DB.

J Clin Endocrinol Metab. 2018 Sep 1;103(9):3350-3358. doi: 10.1210/jc.2018-00500.


Time-Resolved Fluorescence Assays for Quantification of Insulin Precursors in Plasma and Serum.

Taylor K, Halsall I, Guest PC, Burling K.

Methods Mol Biol. 2018;1735:457-465. doi: 10.1007/978-1-4939-7614-0_33.


Extracellular Lactate: A Novel Measure of T Cell Proliferation.

Grist JT, Jarvis LB, Georgieva Z, Thompson S, Kaur Sandhu H, Burling K, Clarke A, Jackson S, Wills M, Gallagher FA, Jones JL.

J Immunol. 2018 Feb 1;200(3):1220-1226. doi: 10.4049/jimmunol.1700886. Epub 2017 Dec 29.


Novel Mechanism for Buffering Dietary Salt in Humans: Effects of Salt Loading on Skin Sodium, Vascular Endothelial Growth Factor C, and Blood Pressure.

Selvarajah V, Mäki-Petäjä KM, Pedro L, Bruggraber SFA, Burling K, Goodhart AK, Brown MJ, McEniery CM, Wilkinson IB.

Hypertension. 2017 Nov;70(5):930-937. doi: 10.1161/HYPERTENSIONAHA.117.10003. Epub 2017 Oct 3.


mTORC1 in AGRP neurons integrates exteroceptive and interoceptive food-related cues in the modulation of adaptive energy expenditure in mice.

Burke LK, Darwish T, Cavanaugh AR, Virtue S, Roth E, Morro J, Liu SM, Xia J, Dalley JW, Burling K, Chua S, Vidal-Puig T, Schwartz GJ, Blouet C.

Elife. 2017 May 23;6. pii: e22848. doi: 10.7554/eLife.22848.


INNOVATE: A prospective cohort study combining serum and urinary biomarkers with novel diffusion-weighted magnetic resonance imaging for the prediction and characterization of prostate cancer.

Johnston E, Pye H, Bonet-Carne E, Panagiotaki E, Patel D, Galazi M, Heavey S, Carmona L, Freeman A, Trevisan G, Allen C, Kirkham A, Burling K, Stevens N, Hawkes D, Emberton M, Moore C, Ahmed HU, Atkinson D, Rodriguez-Justo M, Ng T, Alexander D, Whitaker H, Punwani S.

BMC Cancer. 2016 Oct 21;16(1):816.


The Prostate Health Index adds predictive value to multi-parametric MRI in detecting significant prostate cancers in a repeat biopsy population.

Gnanapragasam VJ, Burling K, George A, Stearn S, Warren A, Barrett T, Koo B, Gallagher FA, Doble A, Kastner C, Parker RA.

Sci Rep. 2016 Oct 17;6:35364. doi: 10.1038/srep35364.


Assessment of Renal Injury in Patients Undergoing Elective EVAR Using Urinary Neutrophil Gelatin-Associated Lipocalin, Interleukin 18, and Retinol-Binding Protein.

Noorani A, Sadat U, Rollins KE, Chowdhury MM, Tang TY, Harrison SC, Usman A, Burling K, Nordon A, Boyle JR.

Angiology. 2017 Jul;68(6):547-552. doi: 10.1177/0003319716672524. Epub 2016 Oct 5.


Whole blood mRNA in prostate cancer reveals a four-gene androgen regulated panel.

Thomas BC, Kay JD, Menon S, Vowler SL, Dawson SN, Bucklow LJ, Luxton HJ, Johnston T, Massie CE, Pugh M, Warren AY, Barker P, Burling K, Lynch AG, George A, Burge J, Corcoran M, Stearn S, Lamb AD, Sharma NL, Shaw GL, Neal DE, Whitaker HC.

Endocr Relat Cancer. 2016 Oct;23(10):797-812. doi: 10.1530/ERC-16-0287. Epub 2016 Aug 30.


Effects of fasting on serial measurements of hyperpolarized [1-(13) C]pyruvate metabolism in tumors.

Serrao EM, Rodrigues TB, Gallagher FA, Kettunen MI, Kennedy BW, Vowler SL, Burling KA, Brindle KM.

NMR Biomed. 2016 Aug;29(8):1048-55. doi: 10.1002/nbm.3568. Epub 2016 Jun 16.


Heterogeneity of glucagonomas due to differential processing of proglucagon-derived peptides.

Challis BG, Albrechtsen NJ, Bansiya V, Burling K, Barker P, Hartmann B, Gribble F, O'Rahilly S, Holst JJ, Simpson HL.

Endocrinol Diabetes Metab Case Rep. 2015;2015:150105. doi: 10.1530/EDM-15-0105. Epub 2015 Dec 1.


Effects on vitamin D, bone and the kidney of switching from fixed-dose tenofovir disoproxil fumarate/emtricitabine/efavirenz to darunavir/ritonavir monotherapy: a randomized, controlled trial (MIDAS).

Hamzah L, Tiraboschi JM, Iveson H, Toby M, Mant C, Cason J, Burling K, Wandolo E, Jendrulek I, Taylor C, Ibrahim F, Kulasegaram R, Teague A, Post FA, Fox J.

Antivir Ther. 2016;21(4):287-96. doi: 10.3851/IMP3000. Epub 2015 Oct 13.


Effects of renal tubular dysfunction on bone in tenofovir-exposed HIV-positive patients.

Hamzah L, Samarawickrama A, Campbell L, Pope M, Burling K, Fisher M, Gilleece Y, Walker-Bone K, Post FA.

AIDS. 2015 Sep 10;29(14):1785-1792. doi: 10.1097/QAD.0000000000000760.


Characterising the association of latency with α(1)-antitrypsin polymerisation using a novel monoclonal antibody.

Tan L, Perez J, Mela M, Miranda E, Burling KA, Rouhani FN, DeMeo DL, Haq I, Irving JA, Ordóñez A, Dickens JA, Brantly M, Marciniak SJ, Alexander GJ, Gooptu B, Lomas DA.

Int J Biochem Cell Biol. 2015 Jan;58:81-91. doi: 10.1016/j.biocel.2014.11.005. Epub 2014 Nov 13.


Insulin-like peptide 5 is an orexigenic gastrointestinal hormone.

Grosse J, Heffron H, Burling K, Akhter Hossain M, Habib AM, Rogers GJ, Richards P, Larder R, Rimmington D, Adriaenssens AA, Parton L, Powell J, Binda M, Colledge WH, Doran J, Toyoda Y, Wade JD, Aparicio S, Carlton MB, Coll AP, Reimann F, O'Rahilly S, Gribble FM.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11133-8. doi: 10.1073/pnas.1411413111. Epub 2014 Jul 15.


Reusable, robust, and accurate laser-generated photonic nanosensor.

Yetisen AK, Montelongo Y, da Cruz Vasconcellos F, Martinez-Hurtado JL, Neupane S, Butt H, Qasim MM, Blyth J, Burling K, Carmody JB, Evans M, Wilkinson TD, Kubota LT, Monteiro MJ, Lowe CR.

Nano Lett. 2014 Jun 11;14(6):3587-93. doi: 10.1021/nl5012504. Epub 2014 May 20.


Assessment of photosystem II thermoluminescence as a tool to investigate the effects of dehydration and rehydration on the cyclic/chlororespiratory electron pathways in wheat and barley leaves.

Bürling K, Ducruet JM, Cornic G, Hunsche M, Cerovic ZG.

Plant Sci. 2014 Jun;223:116-23. doi: 10.1016/j.plantsci.2014.03.013. Epub 2014 Mar 21.


Home urine C-peptide creatinine ratio can be used to monitor islet transplant function.

Oram RA, Brooks AM, Forbes S, Eckoldt S, Smith RM, Choudhary P, Rosenthal MJ, Johnson P, Rutter MK, Burling KA, McDonald TJ, Shaw JA, Hattersley AT.

Diabetes Care. 2014 Jun;37(6):1737-40. doi: 10.2337/dc13-1266. Epub 2014 Mar 12.


Attainment of metabolic goals in the integrated UK islet transplant program with locally isolated and transported preparations.

Brooks AM, Walker N, Aldibbiat A, Hughes S, Jones G, de Havilland J, Choudhary P, Huang GC, Parrott N, McGowan NW, Casey J, Mumford L, Barker P, Burling K, Hovorka R, Walker M, Smith RM, Forbes S, Rutter MK, Amiel S, Rosenthal MJ, Johnson P, Shaw JA.

Am J Transplant. 2013 Dec;13(12):3236-43. doi: 10.1111/ajt.12469. Epub 2013 Oct 1.


Cannabis use is associated with increased CCL11 plasma levels in young healthy volunteers.

Fernandez-Egea E, Scoriels L, Theegala S, Giro M, Ozanne SE, Burling K, Jones PB.

Prog Neuropsychopharmacol Biol Psychiatry. 2013 Oct 1;46:25-8. doi: 10.1016/j.pnpbp.2013.06.011. Epub 2013 Jun 29.


Leptin levels in children and adults with classic galactosaemia.

Knerr I, Coss KP, Doran PP, Hughes J, Wareham N, Burling K, Treacy EP.

JIMD Rep. 2013;9:125-131. doi: 10.1007/8904_2012_191. Epub 2012 Nov 7.


Presymptomatic detection of powdery mildew infection in winter wheat cultivars by laser-induced fluorescence.

Bürling K, Hunsche M, Noga G.

Appl Spectrosc. 2012 Dec;66(12):1411-9. doi: 10.1366/12-06614.


A new role for lipocalin prostaglandin d synthase in the regulation of brown adipose tissue substrate utilization.

Virtue S, Feldmann H, Christian M, Tan CY, Masoodi M, Dale M, Lelliott C, Burling K, Campbell M, Eguchi N, Voshol P, Sethi JK, Parker M, Urade Y, Griffin JL, Cannon B, Vidal-Puig A.

Diabetes. 2012 Dec;61(12):3139-47. doi: 10.2337/db12-0015. Epub 2012 Aug 24.


Bladder cancer diagnosis and identification of clinically significant disease by combined urinary detection of Mcm5 and nuclear matrix protein 22.

Kelly JD, Dudderidge TJ, Wollenschlaeger A, Okoturo O, Burling K, Tulloch F, Halsall I, Prevost T, Prevost AT, Vasconcelos JC, Robson W, Leung HY, Vasdev N, Pickard RS, Williams GH, Stoeber K.

PLoS One. 2012;7(7):e40305. doi: 10.1371/journal.pone.0040305. Epub 2012 Jul 9.


Lipocalin prostaglandin D synthase and PPARγ2 coordinate to regulate carbohydrate and lipid metabolism in vivo.

Virtue S, Masoodi M, Velagapudi V, Tan CY, Dale M, Suorti T, Slawik M, Blount M, Burling K, Campbell M, Eguchi N, Medina-Gomez G, Sethi JK, Orešič M, Urade Y, Griffin JL, Vidal-Puig A.

PLoS One. 2012;7(7):e39512. doi: 10.1371/journal.pone.0039512. Epub 2012 Jul 5.


Accelerated renal disease is associated with the development of metabolic syndrome in a glucolipotoxic mouse model.

Martínez-García C, Izquierdo A, Velagapudi V, Vivas Y, Velasco I, Campbell M, Burling K, Cava F, Ros M, Oresic M, Vidal-Puig A, Medina-Gomez G.

Dis Model Mech. 2012 Sep;5(5):636-48. doi: 10.1242/dmm.009266. Epub 2012 Jul 5.


Release of vancomycin and gentamicin from a contact lens versus a fibrin coating applied to a contact lens.

Hyatt AJ, Rajan MS, Burling K, Ellington MJ, Tassoni A, Martin KR.

Invest Ophthalmol Vis Sci. 2012 Apr 18;53(4):1946-52. doi: 10.1167/iovs.11-8607.


Analysis of molecular forms of urine Retinol-Binding Protein in Fanconi Syndrome and design of an accurate immunoassay.

Burling KA, Cutillas PR, Church D, Lapsley M, Norden AG.

Clin Chim Acta. 2012 Feb 18;413(3-4):483-9. doi: 10.1016/j.cca.2011.11.007. Epub 2011 Nov 19.


Use of blue-green and chlorophyll fluorescence measurements for differentiation between nitrogen deficiency and pathogen infection in winter wheat.

Bürling K, Hunsche M, Noga G.

J Plant Physiol. 2011 Sep 15;168(14):1641-8. doi: 10.1016/j.jplph.2011.03.016. Epub 2011 Jun 11.


Increased maternal Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) associated with older age at diagnosis of Type 1 diabetes in offspring.

Leech NJ, O'Sullivan J, Avery P, Howey C, Burling K, Iyer S, Pascoe L, Walker M, Cheetham T.

Diabet Med. 2010 Dec;27(12):1450-3.


Increased levels of circulating insulin-related peptides in first-onset, antipsychotic naïve schizophrenia patients.

Guest PC, Wang L, Harris LW, Burling K, Levin Y, Ernst A, Wayland MT, Umrania Y, Herberth M, Koethe D, van Beveren JM, Rothermundt M, McAllister G, Leweke FM, Steiner J, Bahn S.

Mol Psychiatry. 2010 Feb;15(2):118-9. doi: 10.1038/mp.2009.81. No abstract available.


Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals.

Heid IM, Henneman P, Hicks A, Coassin S, Winkler T, Aulchenko YS, Fuchsberger C, Song K, Hivert MF, Waterworth DM, Timpson NJ, Richards JB, Perry JR, Tanaka T, Amin N, Kollerits B, Pichler I, Oostra BA, Thorand B, Frants RR, Illig T, Dupuis J, Glaser B, Spector T, Guralnik J, Egan JM, Florez JC, Evans DM, Soranzo N, Bandinelli S, Carlson OD, Frayling TM, Burling K, Smith GD, Mooser V, Ferrucci L, Meigs JB, Vollenweider P, Dijk KW, Pramstaller P, Kronenberg F, van Duijn CM.

Atherosclerosis. 2010 Feb;208(2):412-20. doi: 10.1016/j.atherosclerosis.2009.11.035. Epub 2009 Dec 2.


A genome-wide association study reveals variants in ARL15 that influence adiponectin levels.

Richards JB, Waterworth D, O'Rahilly S, Hivert MF, Loos RJ, Perry JR, Tanaka T, Timpson NJ, Semple RK, Soranzo N, Song K, Rocha N, Grundberg E, Dupuis J, Florez JC, Langenberg C, Prokopenko I, Saxena R, Sladek R, Aulchenko Y, Evans D, Waeber G, Erdmann J, Burnett MS, Sattar N, Devaney J, Willenborg C, Hingorani A, Witteman JC, Vollenweider P, Glaser B, Hengstenberg C, Ferrucci L, Melzer D, Stark K, Deanfield J, Winogradow J, Grassl M, Hall AS, Egan JM, Thompson JR, Ricketts SL, König IR, Reinhard W, Grundy S, Wichmann HE, Barter P, Mahley R, Kesaniemi YA, Rader DJ, Reilly MP, Epstein SE, Stewart AF, Van Duijn CM, Schunkert H, Burling K, Deloukas P, Pastinen T, Samani NJ, McPherson R, Davey Smith G, Frayling TM, Wareham NJ, Meigs JB, Mooser V, Spector TD; GIANT Consortium.

PLoS Genet. 2009 Dec;5(12):e1000768. doi: 10.1371/journal.pgen.1000768. Epub 2009 Dec 11.


Plasma adiponectin concentrations are associated with body composition and plant-based dietary factors in female twins.

Cassidy A, Skidmore P, Rimm EB, Welch A, Fairweather-Tait S, Skinner J, Burling K, Richards JB, Spector TD, MacGregor AJ.

J Nutr. 2009 Feb;139(2):353-8. doi: 10.3945/jn.108.098681. Epub 2008 Dec 23.


Analysis of the alpha-1-antitrypsin deficient alleles M3S, MZ, and ZZ by biochemical and molecular methods: a family study.

Calapoğlu M, Değer O, Balaban F, Sahin Calapoğlu N, Bülbül Y, Burling K.

Biochem Genet. 2009 Feb;47(1-2):33-41. doi: 10.1007/s10528-008-9204-4. Epub 2008 Dec 13.


Urinary insulin-like growth factor 2 identifies the presence of urothelial carcinoma of the bladder.

Watson JA, Burling K, Fitzpatrick P, Kay E, Kelly J, Fitzpatrick JM, Dervan PA, McCann A.

BJU Int. 2009 Mar;103(5):694-7. doi: 10.1111/j.1464-410X.2008.08213.x. Epub 2008 Nov 25.


Adiponectin gene ADIPOQ SNP associations with serum adiponectin in two female populations and effects of SNPs on promoter activity.

Kyriakou T, Collins LJ, Spencer-Jones NJ, Malcolm C, Wang X, Snieder H, Swaminathan R, Burling KA, Hart DJ, Spector TD, O'Dell SD.

J Hum Genet. 2008;53(8):718-727. doi: 10.1007/s10038-008-0303-1. Epub 2008 Jun 4.


Serum levels of retinol-binding protein 4 and adiponectin in women with polycystic ovary syndrome: associations with visceral fat but no evidence for fat mass-independent effects on pathogenesis in this condition.

Barber TM, Hazell M, Christodoulides C, Golding SJ, Alvey C, Burling K, Vidal-Puig A, Groome NP, Wass JA, Franks S, McCarthy MI.

J Clin Endocrinol Metab. 2008 Jul;93(7):2859-65. doi: 10.1210/jc.2007-2759. Epub 2008 Apr 29.


Plasma adiponectin as a marker of insulin receptor dysfunction: clinical utility in severe insulin resistance.

Semple RK, Cochran EK, Soos MA, Burling KA, Savage DB, Gorden P, O'Rahilly S.

Diabetes Care. 2008 May;31(5):977-9. doi: 10.2337/dc07-2194. Epub 2008 Feb 25.


Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies.

Semple RK, Halberg NH, Burling K, Soos MA, Schraw T, Luan J, Cochran EK, Dunger DB, Wareham NJ, Scherer PE, Gorden P, O'Rahilly S.

Diabetes. 2007 Jun;56(6):1712-7. Epub 2007 Feb 26.


Serum adiponectin and bone mineral density in women.

Richards JB, Valdes AM, Burling K, Perks UC, Spector TD.

J Clin Endocrinol Metab. 2007 Apr;92(4):1517-23. Epub 2007 Jan 30.


Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator-activated receptor gamma function (P465L PPARgamma) in mice.

Gray SL, Nora ED, Grosse J, Manieri M, Stoeger T, Medina-Gomez G, Burling K, Wattler S, Russ A, Yeo GS, Chatterjee VK, O'Rahilly S, Voshol PJ, Cinti S, Vidal-Puig A.

Diabetes. 2006 Oct;55(10):2669-77.


Health effects of subchronic exposure to diesel-water-methanol emulsion emission.

Reed MD, Blair LF, Burling K, Daly I, Gigliotti AP, Gudi R, Mercieca MD, McDonald JD, O'Callaghan JP, Seilkop SK, Ronskoh NL, Wagner VO, Kraska RC.

Toxicol Ind Health. 2006 Mar;22(2):65-85.


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