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Items: 1 to 50 of 114

1.

Exposure to hexavalent chromium resulted in significantly higher tissue chromium burden compared with trivalent chromium following similar oral doses to male F344/N rats and female B6C3F1 mice.

Collins BJ, Stout MD, Levine KE, Kissling GE, Melnick RL, Fennell TR, Walden R, Abdo K, Pritchard JB, Fernando RA, Burka LT, Hooth MJ.

Toxicol Sci. 2010 Dec;118(2):368-79. doi: 10.1093/toxsci/kfq263. Epub 2010 Sep 15.

2.

Metabolism and disposition of [14C]dibromoacetonitrile in rats and mice following oral and intravenous administration.

Mathews JM, Pulliam D Jr, Black SR, Burka LT.

Xenobiotica. 2010 Jul;40(7):499-509. doi: 10.3109/00498251003802298.

PMID:
20429840
3.

Effect of dose volume on the toxicokinetics of acrylamide and its metabolites and 2-deoxy-D-glucose.

Ghanayem BI, Bai R, Burka LT.

Drug Metab Dispos. 2009 Feb;37(2):259-63. doi: 10.1124/dmd.108.024265. Epub 2008 Nov 20.

4.

Estrogenic phenol and catechol metabolites of PCBs modulate catechol-O-methyltransferase expression via the estrogen receptor: potential contribution to cancer risk.

Ho PW, Garner CE, Ho JW, Leung KC, Chu AC, Kwok KH, Kung MH, Burka LT, Ramsden DB, Ho SL.

Curr Drug Metab. 2008 May;9(4):304-9.

PMID:
18473748
5.

Neuronal effects of 4-t-Butylcatechol: a model for catechol-containing antioxidants.

Lo YC, Liu Y, Lin YC, Shih YT, Liu CM, Burka LT.

Toxicol Appl Pharmacol. 2008 Apr 15;228(2):247-55. doi: 10.1016/j.taap.2007.12.001. Epub 2007 Dec 14.

6.

Chemical and enzymatic oxidation of furosemide: formation of pyridinium salts.

Chen LJ, Burka LT.

Chem Res Toxicol. 2007 Dec;20(12):1741-4. Epub 2007 Oct 4.

PMID:
17914885
7.

Metabolism and disposition of n-butyl glycidyl ether in F344 rats and B6C3F1 mice.

Chen LJ, Lebetkin EH, Nwakpuda EI, Burka LT.

Drug Metab Dispos. 2007 Dec;35(12):2218-24. Epub 2007 Sep 17.

PMID:
17875671
8.

14C-labeled pulegone and metabolites binding to alpha2u-globulin in kidneys of male F-344 rats.

Ferguson LJ, Lebetkin EH, Lih FB, Tomer KB, Parkinson HD, Borghoff SJ, Burka LT.

J Toxicol Environ Health A. 2007 Sep;70(17):1416-23.

PMID:
17687727
9.

Immunohistochemical analysis of expressions of hepatic cytochrome P450 in F344 rats following oral treatment with kava extract.

Clayton NP, Yoshizawa K, Kissling GE, Burka LT, Chan PC, Nyska A.

Exp Toxicol Pathol. 2007 Jan;58(4):223-36. Epub 2006 Oct 23.

10.

Metabolism of furans in vitro: ipomeanine and 4-ipomeanol.

Chen LJ, DeRose EF, Burka LT.

Chem Res Toxicol. 2006 Oct;19(10):1320-9.

PMID:
17040101
12.
13.

Metabolism and disposition of 1-bromopropane in rats and mice following inhalation or intravenous administration.

Garner CE, Sumner SC, Davis JG, Burgess JP, Yueh Y, Demeter J, Zhan Q, Valentine J, Jeffcoat AR, Burka LT, Mathews JM.

Toxicol Appl Pharmacol. 2006 Aug 15;215(1):23-36. Epub 2006 Mar 2.

PMID:
16513153
14.
15.

Metabolism and disposition of juglone in male F344 rats.

Chen LJ, Lebetkin EH, Burka LT.

Xenobiotica. 2005 Oct-Nov;35(10-11):1019-34.

PMID:
16393859
16.

Differential expression of CYP1A, 2B, and 3A genes in the F344 rat following exposure to a polybrominated diphenyl ether mixture or individual components.

Sanders JM, Burka LT, Smith CS, Black W, James R, Cunningham ML.

Toxicol Sci. 2005 Nov;88(1):127-33. Epub 2005 Aug 17.

PMID:
16107549
17.

Pharmacokinetics and disposition of the kavalactone kawain: interaction with kava extract and kavalactones in vivo and in vitro.

Mathews JM, Etheridge AS, Valentine JL, Black SR, Coleman DP, Patel P, So J, Burka LT.

Drug Metab Dispos. 2005 Oct;33(10):1555-63. Epub 2005 Jul 20.

PMID:
16033948
18.

Transcriptional profiling of the left and median liver lobes of male f344/n rats following exposure to acetaminophen.

Irwin RD, Parker JS, Lobenhofer EK, Burka LT, Blackshear PE, Vallant MK, Lebetkin EH, Gerken DF, Boorman GA.

Toxicol Pathol. 2005;33(1):111-7.

PMID:
15805062
19.
20.

Toxicology and carcinogenesis studies of microencapsulated trans-cinnamaldehyde in rats and mice.

Hooth MJ, Sills RC, Burka LT, Haseman JK, Witt KL, Orzech DP, Fuciarelli AF, Graves SW, Johnson JD, Bucher JR.

Food Chem Toxicol. 2004 Nov;42(11):1757-68.

PMID:
15350673
22.

Lung deposition and clearance of inhaled vanadium pentoxide in chronically exposed F344 rats and B6C3F1 mice.

Dill JA, Lee KM, Mellinger KH, Bates DJ, Burka LT, Roycroft JH.

Toxicol Sci. 2004 Jan;77(1):6-18. Epub 2003 Nov 4.

PMID:
14600283
23.

Metabolism of (R)-(+)-menthofuran in Fischer-344 rats: identification of sulfonic acid metabolites.

Chen LJ, Lebetkin EH, Burka LT.

Drug Metab Dispos. 2003 Oct;31(10):1208-13.

PMID:
12975329
24.

Comparative disposition of (R)-(+)-pulegone in B6C3F1 mice and F344 rats.

Chen LJ, Lebetkin EH, Burka LT.

Drug Metab Dispos. 2003 Jul;31(7):892-9.

PMID:
12814966
25.

Alpha 2u-globulin nephropathy and carcinogenicity following exposure to decalin (decahydronaphthalene) in F344/N rats.

Dill JA, Lee KM, Renne RA, Miller RA, Fuciarelli AF, Gideon KM, Chan PC, Burka LT, Roycroft JH.

Toxicol Sci. 2003 Apr;72(2):223-34.

PMID:
12660359
26.

Single administration toxicokinetic studies of decalin (decahydronaphthalene) in rats and mice.

Dill JA, Fuciarelli AF, Lee KM, Mellinger KM, Chan PC, Burka LT, Roycroft JH.

Toxicol Sci. 2003 Apr;72(2):210-22.

PMID:
12660358
27.

Mouse bone marrow micronucleus test results do not predict the germ cell mutagenicity of N-hydroxymethylacrylamide in the mouse dominant lethal assay.

Witt KL, Hughes LA, Burka LT, McFee AF, Mathews JM, Black SL, Bishop JB.

Environ Mol Mutagen. 2003;41(2):111-20.

PMID:
12605380
28.

Disposition of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone (mx) in b6c3f1 mice and f344 rats.

Lebetkin EH, Chen LJ, Burka LT.

J Toxicol Environ Health A. 2002 Dec 27;65(24):2101-18.

PMID:
12515589
29.

Carcinogenic potential of o-nitrotoluene and p-nitrotoluene.

Dunnick JK, Burka LT, Mahler J, Sills R.

Toxicology. 2003 Feb 1;183(1-3):221-34.

PMID:
12504353
30.

Metabolism of (R)-(+)-pulegone in F344 rats.

Chen LJ, Lebetkin EH, Burka LT.

Drug Metab Dispos. 2001 Dec;29(12):1567-77.

PMID:
11717176
31.

Tyrosine iminoxyl radical formation from tyrosyl radical/nitric oxide and nitrosotyrosine.

Sturgeon BE, Glover RE, Chen YR, Burka LT, Mason RP.

J Biol Chem. 2001 Dec 7;276(49):45516-21. Epub 2001 Sep 10.

32.

Comparative xenobiotic metabolism between Tg.AC and p53+/- genetically altered mice and their respective wild types.

Sanders JM, Burka LT, Chanas B, Matthews HB.

Toxicol Sci. 2001 May;61(1):54-61.

PMID:
11294974
33.

Metabolism and disposition of luminol in the rat.

Sanders JM, Chen LJ, Burka LT, Matthews HB.

Xenobiotica. 2000 Mar;30(3):263-72.

PMID:
10752641
34.
35.

Catechol metabolites of polychlorinated biphenyls inhibit the catechol-O-methyltransferase-mediated metabolism of catechol estrogens.

Garner CE, Burka LT, Etheridge AE, Matthews HB.

Toxicol Appl Pharmacol. 2000 Jan 15;162(2):115-23.

PMID:
10637135
36.

In vivo production of nitric oxide after administration of cyclohexanone oxime.

Glover RE, Corbett JT, Burka LT, Mason RP.

Chem Res Toxicol. 1999 Oct;12(10):952-7.

PMID:
10525271
37.

Identification of urinary metabolites of isoprene in rats and comparison with mouse urinary metabolites.

Buckley LA, Coleman DP, Burgess JP, Thomas BF, Burka LT, Jeffcoat AR.

Drug Metab Dispos. 1999 Jul;27(7):848-54.

PMID:
10383931
38.

Distribution and metabolism of (5-hydroxymethyl)furfural in male F344 rats and B6C3F1 mice after oral administration.

Godfrey VB, Chen LJ, Griffin RJ, Lebetkin EH, Burka LT.

J Toxicol Environ Health A. 1999 Jun 11;57(3):199-210.

PMID:
10376886
39.

Role of cytochrome P-450 2E1 in methacrylonitrile metabolism and disposition.

Ghanayem BI, Sanders JM, Chanas B, Burka LT, Gonzalez FJ.

J Pharmacol Exp Ther. 1999 May;289(2):1054-9.

PMID:
10215687
40.

In vitro estrogenicity of the catechol metabolites of selected polychlorinated biphenyls.

Garner CE, Jefferson WN, Burka LT, Matthews HB, Newbold RR.

Toxicol Appl Pharmacol. 1999 Jan 15;154(2):188-97.

PMID:
9925803
41.

Toxicokinetics of inhaled 2-butoxyethanol and its major metabolite, 2-butoxyacetic acid, in F344 rats and B6C3F1 mice.

Dill JA, Lee KM, Bates DJ, Anderson DJ, Johnson RE, Chou BJ, Burka LT, Roycroft JH.

Toxicol Appl Pharmacol. 1998 Dec;153(2):227-42.

PMID:
9878593
42.

Disposition of methyl ethyl ketoxime in the rat after oral, intravenous and dermal administration.

Burka LT, Black SR, Mathews JM.

Xenobiotica. 1998 Oct;28(10):1005-15.

PMID:
9849647
43.

Disposition of butanal oxime in rat following oral, intravenous and dermal administration.

Mathews JM, Black SR, Burka LT.

Xenobiotica. 1998 Aug;28(8):767-77.

PMID:
9741955
44.

Disposition of 2-methylimidazole in rats.

Sanders JM, Griffin RJ, Burka LT, Matthews HB.

J Toxicol Environ Health A. 1998 May 22;54(2):121-32.

PMID:
9652548
45.

Metabolism and disposition of phenolphthalein in male and female F344 rats and B6C3F1 mice.

Griffin RJ, Godfrey VB, Burka LT.

Toxicol Sci. 1998 Apr;42(2):73-81.

PMID:
9579019
46.

The effects of perinatal/juvenile methoxychlor exposure on adult rat nervous, immune, and reproductive system function.

Chapin RE, Harris MW, Davis BJ, Ward SM, Wilson RE, Mauney MA, Lockhart AC, Smialowicz RJ, Moser VC, Burka LT, Collins BJ.

Fundam Appl Toxicol. 1997 Nov;40(1):138-57.

PMID:
9398496
47.
48.

Determination of tamoxifen and metabolites in serum by capillary electrophoresis using a nonaqueous buffer system.

Sanders JM, Burka LT, Shelby MD, Newbold RR, Cunningham ML.

J Chromatogr B Biomed Sci Appl. 1997 Jul 18;695(1):181-5.

PMID:
9271143
49.

Biliary elimination of oral 2,4-dichlorophenoxyacetic acid and its metabolites in male and female Sprague-Dawley rats, B6C3F1 mice, and Syrian hamsters.

Griffin RJ, Salemme J, Clark J, Myers P, Burka LT.

J Toxicol Environ Health. 1997 Jul;51(4):401-13.

PMID:
9202719
50.

Purpose and guidelines for toxicokinetic studies within the National Toxicology Program.

Buchanan JR, Burka LT, Melnick RL.

Environ Health Perspect. 1997 May;105(5):468-71. Review.

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