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Items: 20


Reporting and connecting cell type names and gating definitions through ontologies.

Overton JA, Vita R, Dunn P, Burel JG, Bukhari SAC, Cheung KH, Kleinstein SH, Diehl AD, Peters B.

BMC Bioinformatics. 2019 Apr 25;20(Suppl 5):182. doi: 10.1186/s12859-019-2725-5.


Circulating T cell-monocyte complexes are markers of immune perturbations.

Burel JG, Pomaznoy M, Lindestam Arlehamn CS, Weiskopf D, da Silva Antunes R, Jung Y, Babor M, Schulten V, Seumois G, Greenbaum JA, Premawansa S, Premawansa G, Wijewickrama A, Vidanagama D, Gunasena B, Tippalagama R, deSilva AD, Gilman RH, Saito M, Taplitz R, Ley K, Vijayanand P, Sette A, Peters B.

Elife. 2019 Jun 25;8. pii: e46045. doi: 10.7554/eLife.46045.


Host Transcriptomics as a Tool to Identify Diagnostic and Mechanistic Immune Signatures of Tuberculosis.

Burel JG, Babor M, Pomaznoy M, Lindestam Arlehamn CS, Khan N, Sette A, Peters B.

Front Immunol. 2019 Feb 19;10:221. doi: 10.3389/fimmu.2019.00221. eCollection 2019. Review.


DAFi: A directed recursive data filtering and clustering approach for improving and interpreting data clustering identification of cell populations from polychromatic flow cytometry data.

Lee AJ, Chang I, Burel JG, Lindestam Arlehamn CS, Mandava A, Weiskopf D, Peters B, Sette A, Scheuermann RH, Qian Y.

Cytometry A. 2018 Jun;93(6):597-610. doi: 10.1002/cyto.a.23371. Epub 2018 Apr 17.


Discovering transcriptional signatures of disease for diagnosis versus mechanism.

Burel JG, Peters B.

Nat Rev Immunol. 2018 May;18(5):289-290. doi: 10.1038/nri.2018.26. Epub 2018 Apr 9. No abstract available.


Transcriptomic Analysis of CD4+ T Cells Reveals Novel Immune Signatures of Latent Tuberculosis.

Burel JG, Lindestam Arlehamn CS, Khan N, Seumois G, Greenbaum JA, Taplitz R, Gilman RH, Saito M, Vijayanand P, Sette A, Peters B.

J Immunol. 2018 May 1;200(9):3283-3290. doi: 10.4049/jimmunol.1800118. Epub 2018 Mar 30.


Dichotomous miR expression and immune responses following primary blood-stage malaria.

Burel JG, Apte SH, Groves PL, Boyle MJ, Langer C, Beeson JG, McCarthy JS, Doolan DL.

JCI Insight. 2017 Aug 3;2(15). pii: 93434. doi: 10.1172/jci.insight.93434. eCollection 2017 Aug 3.


Early Immune Regulatory Changes in a Primary Controlled Human Plasmodium vivax Infection: CD1c+ Myeloid Dendritic Cell Maturation Arrest, Induction of the Kynurenine Pathway, and Regulatory T Cell Activation.

Woodberry T, Loughland JR, Minigo G, Burel JG, Amante FH, Piera KA, McNeil Y, Yeo TW, Good MF, Doolan DL, Engwerda CR, McCarthy JS, Anstey NM.

Infect Immun. 2017 May 23;85(6). pii: e00986-16. doi: 10.1128/IAI.00986-16. Print 2017 Jun.


Polyfunctional and IFN-γ monofunctional human CD4+ T cell populations are molecularly distinct.

Burel JG, Apte SH, Groves PL, McCarthy JS, Doolan DL.

JCI Insight. 2017 Feb 9;2(3):e87499. doi: 10.1172/jci.insight.87499.


An Integrated Workflow To Assess Technical and Biological Variability of Cell Population Frequencies in Human Peripheral Blood by Flow Cytometry.

Burel JG, Qian Y, Lindestam Arlehamn C, Weiskopf D, Zapardiel-Gonzalo J, Taplitz R, Gilman RH, Saito M, de Silva AD, Vijayanand P, Scheuermann RH, Sette A, Peters B.

J Immunol. 2017 Feb 15;198(4):1748-1758. doi: 10.4049/jimmunol.1601750. Epub 2017 Jan 9.


Plasmodium vivax but Not Plasmodium falciparum Blood-Stage Infection in Humans Is Associated with the Expansion of a CD8+ T Cell Population with Cytotoxic Potential.

Burel JG, Apte SH, McCarthy JS, Doolan DL.

PLoS Negl Trop Dis. 2016 Dec 8;10(12):e0005031. doi: 10.1371/journal.pntd.0005031. eCollection 2016 Dec.


Reduced Plasmodium Parasite Burden Associates with CD38+ CD4+ T Cells Displaying Cytolytic Potential and Impaired IFN-γ Production.

Burel JG, Apte SH, Groves PL, Klein K, McCarthy JS, Doolan DL.

PLoS Pathog. 2016 Sep 23;12(9):e1005839. doi: 10.1371/journal.ppat.1005839. eCollection 2016 Sep.


Development of a cytokine-secreting-based assay for the identification, sorting and transcriptomic analysis of polyfunctional human T cells.

Burel JG, Apte SH, Doolan DL.

Eur Cytokine Netw. 2015 Oct-Dec;26(4):67-72. doi: 10.1684/ecn.2015.0369.


Systems Approaches towards Molecular Profiling of Human Immunity.

Burel JG, Apte SH, Doolan DL.

Trends Immunol. 2016 Jan;37(1):53-67. doi: 10.1016/ Epub 2015 Dec 5. Review.


Exome Sequencing to Predict Neoantigens in Melanoma.

Pritchard AL, Burel JG, Neller MA, Hayward NK, Lopez JA, Fatho M, Lennerz V, Wölfel T, Schmidt CW.

Cancer Immunol Res. 2015 Sep;3(9):992-8. doi: 10.1158/2326-6066.CIR-15-0088. Epub 2015 Jun 5.


Asthma is associated with multiple alterations in anti-viral innate signalling pathways.

Pritchard AL, White OJ, Burel JG, Carroll ML, Phipps S, Upham JW.

PLoS One. 2014 Sep 9;9(9):e106501. doi: 10.1371/journal.pone.0106501. eCollection 2014.


Clinical factors associated with the humoral immune response to influenza vaccination in chronic obstructive pulmonary disease.

Nath KD, Burel JG, Shankar V, Pritchard AL, Towers M, Looke D, Davies JM, Upham JW.

Int J Chron Obstruct Pulmon Dis. 2014;9:51-6. doi: 10.2147/COPD.S53590. Epub 2013 Dec 24.


Reduced rhinovirus-specific antibodies are associated with acute exacerbations of chronic obstructive pulmonary disease requiring hospitalisation.

Yerkovich ST, Hales BJ, Carroll ML, Burel JG, Towers MA, Smith DJ, Thomas WR, Upham JW.

BMC Pulm Med. 2012 Jul 31;12:37. doi: 10.1186/1471-2466-12-37.


Innate interferons inhibit allergen and microbial specific T(H)2 responses.

Pritchard AL, White OJ, Burel JG, Upham JW.

Immunol Cell Biol. 2012 Nov;90(10):974-7. doi: 10.1038/icb.2012.39. Epub 2012 Jul 24.


Innate IFNs and plasmacytoid dendritic cells constrain Th2 cytokine responses to rhinovirus: a regulatory mechanism with relevance to asthma.

Pritchard AL, Carroll ML, Burel JG, White OJ, Phipps S, Upham JW.

J Immunol. 2012 Jun 15;188(12):5898-905. doi: 10.4049/jimmunol.1103507. Epub 2012 May 18.

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