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Items: 1 to 50 of 197

1.

Sex-independent expression of chloride/formate exchanger Cfex (Slc26a6) in rat pancreas, small intestine, and liver, and male-dominant expression in kidneys.

Karaica D, Breljak D, Lončar J, Lovrić M, Micek V, Vrhovac Madunić I, Brzica H, Herak-Kramberger CM, Dupor JI, Ljubojević M, Smital T, Vogrinc Ž, Burckhardt G, Burckhardt BC, Sabolić I.

Arh Hig Rada Toksikol. 2018 Dec 1;69(4):286-303. doi: 10.2478/aiht-2018-69-3157.

PMID:
30864378
2.

Interaction of Excitatory Amino Acid Transporters 1 - 3 (EAAT1, EAAT2, EAAT3) with N-Carbamoylglutamate and N-Acetylglutamate.

Burckhardt BC, Burckhardt G.

Cell Physiol Biochem. 2017;43(5):1907-1916. doi: 10.1159/000484110. Epub 2017 Oct 20.

3.

Differential Interaction of Dantrolene, Glafenine, Nalidixic Acid, and Prazosin with Human Organic Anion Transporters 1 and 3.

Burckhardt BC, Henjakovic M, Hagos Y, Burckhardt G.

J Pharmacol Exp Ther. 2017 Sep;362(3):450-458. doi: 10.1124/jpet.117.241406. Epub 2017 Jun 19.

PMID:
28630284
4.

Erratum to: Counter-flow suggests transport of dantrolene and 5-OH dantrolene by the organic anion transporters 2 (OAT2) and 3 (OAT3).

Burckhardt BC, Henjakovic M, Hagos Y, Burckhardt G.

Pflugers Arch. 2016 Nov;468(11-12):1919-1920. No abstract available.

PMID:
27889824
5.

Counter-flow suggests transport of dantrolene and 5-OH dantrolene by the organic anion transporters 2 (OAT2) and 3 (OAT3).

Burckhardt BC, Henjakovic M, Hagos Y, Burckhardt G.

Pflugers Arch. 2016 Nov;468(11-12):1909-1918. Epub 2016 Nov 3. Erratum in: Pflugers Arch. 2016 Nov;468(11-12):1919-1920.

PMID:
27812757
6.

Distribution of organic anion transporters NaDC3 and OAT1-3 along the human nephron.

Breljak D, Ljubojević M, Hagos Y, Micek V, Balen Eror D, Vrhovac Madunić I, Brzica H, Karaica D, Radović N, Kraus O, Anzai N, Koepsell H, Burckhardt G, Burckhardt BC, Sabolić I.

Am J Physiol Renal Physiol. 2016 Jul 1;311(1):F227-38. doi: 10.1152/ajprenal.00113.2016. Epub 2016 Apr 6.

7.

The Isoquinolone Derived Prolyl Hydroxylase Inhibitor ICA Is a Potent Substrate of the Organic Anion Transporters 1 and 3.

Schulz K, Hagos Y, Burckhardt G, Schley G, Burzlaff N, Willam C, Burckhardt BC.

Nephron. 2015;131(4):285-9. doi: 10.1159/000442531. Epub 2015 Dec 8.

PMID:
26640952
8.

In female rats, ethylene glycol treatment elevates protein expression of hepatic and renal oxalate transporter sat-1 (Slc26a1) without inducing hyperoxaluria.

Breljak D, Brzica H, Vrhovac I, Micek V, Karaica D, Ljubojević M, Sekovanić A, Jurasović J, Rašić D, Peraica M, Lovrić M, Schnedler N, Henjakovic M, Wegner W, Burckhardt G, Burckhardt BC, Sabolić I.

Croat Med J. 2015 Oct;56(5):447-59.

9.

Human organic anion transporter 2 is distinct from organic anion transporters 1 and 3 with respect to transport function.

Henjakovic M, Hagos Y, Krick W, Burckhardt G, Burckhardt BC.

Am J Physiol Renal Physiol. 2015 Nov 15;309(10):F843-51. doi: 10.1152/ajprenal.00140.2015. Epub 2015 Sep 16.

10.

Next generation sequencing of sex-specific genes in the livers of obese ZSF1 rats.

Babelova A, Burckhardt BC, Salinas-Riester G, Pommerenke C, Burckhardt G, Henjakovic M.

Genomics. 2015 Oct;106(4):204-13. doi: 10.1016/j.ygeno.2015.07.006. Epub 2015 Jul 19.

11.

Sex-differences in renal expression of selected transporters and transcription factors in lean and obese Zucker spontaneously hypertensive fatty rats.

Babelova A, Burckhardt BC, Wegner W, Burckhardt G, Henjakovic M.

J Diabetes Res. 2015;2015:483238. doi: 10.1155/2015/483238. Epub 2015 Jan 29.

12.

Interaction of human organic anion transporter polypeptides 1B1 and 1B3 with antineoplastic compounds.

Marada VV, Flörl S, Kühne A, Burckhardt G, Hagos Y.

Eur J Med Chem. 2015 Mar 6;92:723-31. doi: 10.1016/j.ejmech.2015.01.011. Epub 2015 Jan 8.

PMID:
25618019
13.

[Medical school admission test at the University of Goettingen - which applicants will benefit?].

Simmenroth-Nayda A, Meskauskas E, Burckhardt G, Görlich Y.

Z Evid Fortbild Qual Gesundhwes. 2014;108(10):609-17. doi: 10.1016/j.zefq.2014.09.024. Epub 2014 Nov 20. German.

PMID:
25499117
14.

Quality management of clinical-practical instruction for Practical Year medical students in Germany - proposal for a catalogue of criteria from the German Society of Medical Education.

Raes P, Angstwurm M, Berberat P, Kadmon M, Rotgans J, Streitlein-Böhme I, Burckhardt G, Fischer MR.

GMS Z Med Ausbild. 2014 Nov 17;31(4):Doc49. doi: 10.3205/zma000941. eCollection 2014.

15.

Interaction of human organic anion transporter 2 (OAT2) and sodium taurocholate cotransporting polypeptide (NTCP) with antineoplastic drugs.

Marada VV, Flörl S, Kühne A, Müller J, Burckhardt G, Hagos Y.

Pharmacol Res. 2015 Jan;91:78-87. doi: 10.1016/j.phrs.2014.11.002. Epub 2014 Dec 4.

PMID:
25481222
16.

Renal human organic anion transporter 3 increases the susceptibility of lymphoma cells to bendamustine uptake.

Hagos Y, Hundertmark P, Shnitsar V, Marada VV, Wulf G, Burckhardt G.

Am J Physiol Renal Physiol. 2015 Feb 15;308(4):F330-8. doi: 10.1152/ajprenal.00467.2014. Epub 2014 Dec 4.

17.

Transporters involved in renal excretion of N-carbamoylglutamate, an orphan drug to treat inborn n-acetylglutamate synthase deficiency.

Schwob E, Hagos Y, Burckhardt G, Burckhardt BC.

Am J Physiol Renal Physiol. 2014 Dec 15;307(12):F1373-9. doi: 10.1152/ajprenal.00482.2014. Epub 2014 Oct 29.

18.

Transcriptional regulation of human organic anion transporter 1 by B-cell CLL/lymphoma 6.

Wegner W, Burckhardt G, Henjakovic M.

Am J Physiol Renal Physiol. 2014 Dec 1;307(11):F1283-91. doi: 10.1152/ajprenal.00426.2014. Epub 2014 Sep 18.

19.

HNF4α induced chemosensitivity to oxaliplatin and 5-FU mediated by OCT1 and CNT3 in renal cell carcinoma.

Hagos Y, Wegner W, Kuehne A, Floerl S, Marada VV, Burckhardt G, Henjakovic M.

J Pharm Sci. 2014 Oct;103(10):3326-34. doi: 10.1002/jps.24128. Epub 2014 Aug 29.

PMID:
25175346
20.

Oxalate: from the environment to kidney stones.

Brzica H, Breljak D, Burckhardt BC, Burckhardt G, Sabolić I.

Arh Hig Rada Toksikol. 2013 Dec;64(4):609-30. doi: 10.2478/10004-1254-64-2013-2428. Review.

PMID:
24384768
21.

Glutathione is a low-affinity substrate of the human sodium-dependent dicarboxylate transporter.

Schorbach L, Krick W, Burckhardt G, Burckhardt BC.

Nephron Physiol. 2013;124(1-2):1-5. doi: 10.1159/000356419. Epub 2013 Nov 14.

PMID:
24247155
22.

Human organic anion transporter OAT1 is not responsible for glutathione transport but mediates transport of glutamate derivatives.

Hagos Y, Burckhardt G, Burckhardt BC.

Am J Physiol Renal Physiol. 2013 Feb 15;304(4):F403-9. doi: 10.1152/ajprenal.00412.2012. Epub 2012 Dec 19.

23.

On a fully closed state of native human type-1 VDAC enriched in Nonidet P40.

Thinnes FP, Burckhardt G.

Mol Genet Metab. 2012 Nov;107(3):632-3. doi: 10.1016/j.ymgme.2012.08.015. Epub 2012 Aug 29.

PMID:
23000107
24.

α-Ketoglutarate-related inhibitors of HIF prolyl hydroxylases are substrates of renal organic anion transporters 1 (OAT1) and 4 (OAT4).

Hagos Y, Schley G, Schödel J, Krick W, Burckhardt G, Willam C, Burckhardt BC.

Pflugers Arch. 2012 Oct;464(4):367-74. Epub 2012 Aug 9.

PMID:
22875277
25.

Drug transport by Organic Anion Transporters (OATs).

Burckhardt G.

Pharmacol Ther. 2012 Oct;136(1):106-30. doi: 10.1016/j.pharmthera.2012.07.010. Epub 2012 Jul 25. Review.

PMID:
22841915
26.

Piloting an outcome-based programme evaluation tool in undergraduate medical education.

Raupach T, Schiekirka S, Münscher C, Beißbarth T, Himmel W, Burckhardt G, Pukrop T.

GMS Z Med Ausbild. 2012;29(3):Doc44. doi: 10.3205/zma000814. Epub 2012 May 15.

27.

Male-dominant activation of rat renal organic anion transporter 1 (Oat1) and 3 (Oat3) expression by transcription factor BCL6.

Wegner W, Burckhardt BC, Burckhardt G, Henjakovic M.

PLoS One. 2012;7(4):e35556. doi: 10.1371/journal.pone.0035556. Epub 2012 Apr 18.

28.

Human organic cation transporter 1 is expressed in lymphoma cells and increases susceptibility to irinotecan and paclitaxel.

Gupta S, Wulf G, Henjakovic M, Koepsell H, Burckhardt G, Hagos Y.

J Pharmacol Exp Ther. 2012 Apr;341(1):16-23. doi: 10.1124/jpet.111.190561. Epub 2011 Dec 27.

PMID:
22202118
29.

Interaction of human multidrug and toxin extrusion 1 (MATE1) transporter with antineoplastic agents.

Grottker J, Rosenberger A, Burckhardt G, Hagos Y.

Drug Metabol Drug Interact. 2011;26(4):181-9. doi: 10.1515/DMDI.2011.024. Epub 2011 Nov 7.

PMID:
22149660
30.

Differential interaction of dicarboxylates with human sodium-dicarboxylate cotransporter 3 and organic anion transporters 1 and 3.

Kaufhold M, Schulz K, Breljak D, Gupta S, Henjakovic M, Krick W, Hagos Y, Sabolic I, Burckhardt BC, Burckhardt G.

Am J Physiol Renal Physiol. 2011 Nov;301(5):F1026-34. doi: 10.1152/ajprenal.00169.2011. Epub 2011 Aug 24.

31.

Towards outcome-based programme evaluation: using student comparative self-assessments to determine teaching effectiveness.

Raupach T, Münscher C, Beissbarth T, Burckhardt G, Pukrop T.

Med Teach. 2011;33(8):e446-53. doi: 10.3109/0142159X.2011.586751.

PMID:
21774642
32.

The sodium-dependent di- and tricarboxylate transporter, NaCT, is not responsible for the uptake of D-, L-2-hydroxyglutarate and 3-hydroxyglutarate into neurons.

Brauburger K, Burckhardt G, Burckhardt BC.

J Inherit Metab Dis. 2011 Apr;34(2):477-82. doi: 10.1007/s10545-010-9268-2. Epub 2011 Jan 25.

33.

SLC22 transporter family proteins as targets for cytostatic uptake into tumor cells.

Gupta S, Burckhardt G, Hagos Y.

Biol Chem. 2011 Jan;392(1-2):117-24. doi: 10.1515/BC.2011.014. Review.

PMID:
21194368
34.

URAT1 mutations cause renal hypouricemia type 1 in Iraqi Jews.

Dinour D, Bahn A, Ganon L, Ron R, Geifman-Holtzman O, Knecht A, Gafter U, Rachamimov R, Sela BA, Burckhardt G, Holtzman EJ.

Nephrol Dial Transplant. 2011 Jul;26(7):2175-81. doi: 10.1093/ndt/gfq722. Epub 2010 Dec 9.

PMID:
21148271
35.

In vitro and in vivo evidence of the importance of organic anion transporters (OATs) in drug therapy.

Burckhardt G, Burckhardt BC.

Handb Exp Pharmacol. 2011;(201):29-104. doi: 10.1007/978-3-642-14541-4_2. Review.

PMID:
21103968
36.

Glyoxylate is a substrate of the sulfate-oxalate exchanger, sat-1, and increases its expression in HepG2 cells.

Schnedler N, Burckhardt G, Burckhardt BC.

J Hepatol. 2011 Mar;54(3):513-20. doi: 10.1016/j.jhep.2010.07.036. Epub 2010 Sep 19.

PMID:
21093948
37.

New clues for nephrotoxicity induced by ifosfamide: preferential renal uptake via the human organic cation transporter 2.

Ciarimboli G, Holle SK, Vollenbröcker B, Hagos Y, Reuter S, Burckhardt G, Bierer S, Herrmann E, Pavenstädt H, Rossi R, Kleta R, Schlatter E.

Mol Pharm. 2011 Feb 7;8(1):270-9. doi: 10.1021/mp100329u. Epub 2010 Dec 2.

PMID:
21077648
38.

Professor Karl Julius Ullrich--in memoriam.

Murer H, Burckhardt G.

Kidney Int. 2010 Nov;78(9):827-8. doi: 10.1038/ki.2010.368. No abstract available.

39.

Organic anion transporter 3 (OAT3) and renal transport of the metal chelator 2,3-dimercapto-1-propanesulfonic acid (DMPS).

Rödiger M, Zhang X, Ugele B, Gersdorff N, Wright SH, Burckhardt G, Bahn A.

Can J Physiol Pharmacol. 2010 Feb;88(2):141-6. doi: 10.1139/Y09-123.

40.

[A contribution to the needs assessment of faculty development measures in medical schools].

Raupach T, Spering C, Bäumler C, Burckhardt G, Trümper L, Pukrop T.

Med Klin (Munich). 2009 Nov 15;104(11):841-5. doi: 10.1007/s00063-009-1180-x. Epub 2009 Nov 17. German.

PMID:
19916073
41.

Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy.

Bakhiya N, Arlt VM, Bahn A, Burckhardt G, Phillips DH, Glatt H.

Toxicology. 2009 Oct 1;264(1-2):74-9. doi: 10.1016/j.tox.2009.07.014. Epub 2009 Jul 28.

PMID:
19643159
42.

Influx and efflux transport as determinants of melphalan cytotoxicity: Resistance to melphalan in MDR1 overexpressing tumor cell lines.

Kühne A, Tzvetkov MV, Hagos Y, Lage H, Burckhardt G, Brockmöller J.

Biochem Pharmacol. 2009 Jul 1;78(1):45-53. doi: 10.1016/j.bcp.2009.03.026. Epub 2009 Apr 5.

PMID:
19447222
43.

Ability of sat-1 to transport sulfate, bicarbonate, or oxalate under physiological conditions.

Krick W, Schnedler N, Burckhardt G, Burckhardt BC.

Am J Physiol Renal Physiol. 2009 Jul;297(1):F145-54. doi: 10.1152/ajprenal.90401.2008. Epub 2009 Apr 15.

44.

Expression of human organic cation transporter 3 in kidney carcinoma cell lines increases chemosensitivity to melphalan, irinotecan, and vincristine.

Shnitsar V, Eckardt R, Gupta S, Grottker J, Müller GA, Koepsell H, Burckhardt G, Hagos Y.

Cancer Res. 2009 Feb 15;69(4):1494-501. doi: 10.1158/0008-5472.CAN-08-2483. Epub 2009 Feb 3.

45.

The liver and kidney expression of sulfate anion transporter sat-1 in rats exhibits male-dominant gender differences.

Brzica H, Breljak D, Krick W, Lovrić M, Burckhardt G, Burckhardt BC, Sabolić I.

Pflugers Arch. 2009 Apr;457(6):1381-92. doi: 10.1007/s00424-008-0611-5. Epub 2008 Nov 11.

PMID:
19002488
46.

Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13).

Bahn A, Hagos Y, Reuter S, Balen D, Brzica H, Krick W, Burckhardt BC, Sabolic I, Burckhardt G.

J Biol Chem. 2008 Jun 13;283(24):16332-41. doi: 10.1074/jbc.M800737200. Epub 2008 Apr 14.

47.

Membrane translocation of glutaric acid and its derivatives.

Mühlhausen C, Burckhardt BC, Hagos Y, Burckhardt G, Keyser B, Lukacs Z, Ullrich K, Braulke T.

J Inherit Metab Dis. 2008 Apr;31(2):188-93. doi: 10.1007/s10545-008-0825-x. Epub 2008 Apr 4. Review.

PMID:
18404412
48.

Organic anion transporters OAT1 and OAT4 mediate the high affinity transport of glutarate derivatives accumulating in patients with glutaric acidurias.

Hagos Y, Krick W, Braulke T, Mühlhausen C, Burckhardt G, Burckhardt BC.

Pflugers Arch. 2008 Oct;457(1):223-31. doi: 10.1007/s00424-008-0489-2. Epub 2008 Mar 26.

PMID:
18365245
49.

Short- and long-term A3 adenosine receptor activation inhibits the Na+/H+ exchanger NHE3 activity and expression in opossum kidney cells.

Di Sole F, Cerull R, Babich V, Casavola V, Helmle-Roth C, Burckhardt G.

J Cell Physiol. 2008 Jul;216(1):221-33. doi: 10.1002/jcp.21399.

PMID:
18286509
50.

Torasemide transport by organic anion transporters contributes to hyperuricemia.

Hagos Y, Bahn A, Vormfelde SV, Brockmöller J, Burckhardt G.

J Am Soc Nephrol. 2007 Dec;18(12):3101-9. Epub 2007 Oct 31. No abstract available.

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