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Items: 1 to 50 of 222

1.

A shorter working week for everyone: How much paid work is needed for mental health and well-being?

Kamerāde D, Wang S, Burchell B, Balderson SU, Coutts A.

Soc Sci Med. 2019 Jun 10:112353. doi: 10.1016/j.socscimed.2019.06.006. [Epub ahead of print]

2.

Restless legs syndrome is associated with major comorbidities in a population of Danish blood donors.

Didriksen M, Allen RP, Burchell BJ, Thørner LW, Rigas AS, Di Angelantonio E, Nielsen MH, Jennum PJ, Werge T, Erikstrup C, Pedersen OB, Nielsen K, Bruun MT, Burgdorf KS, Sørensen E, Ullum H.

Sleep Med. 2018 May;45:124-131. doi: 10.1016/j.sleep.2018.02.007. Epub 2018 Mar 8.

PMID:
29680420
3.

Prevalence of restless legs syndrome and associated factors in an otherwise healthy population: results from the Danish Blood Donor Study.

Didriksen M, Rigas AS, Allen RP, Burchell BJ, Di Angelantonio E, Nielsen MH, Jennum P, Werge T, Erikstrup C, Pedersen OB, Bruun MT, Burgdorf KS, Sørensen E, Ullum H.

Sleep Med. 2017 Aug;36:55-61. doi: 10.1016/j.sleep.2017.04.014. Epub 2017 May 26.

PMID:
28735922
4.

A novel method for the immunoquantification of UDP-glucuronosyltransferases in human tissue.

Milne AM, Burchell B, Coughtrie MW.

Drug Metab Dispos. 2011 Dec;39(12):2258-63. doi: 10.1124/dmd.111.041699. Epub 2011 Aug 31.

PMID:
21880828
5.

Validation of the self-completed Cambridge-Hopkins questionnaire (CH-RLSq) for ascertainment of restless legs syndrome (RLS) in a population survey.

Allen RP, Burchell BJ, MacDonald B, Hening WA, Earley CJ.

Sleep Med. 2009 Dec;10(10):1097-100. doi: 10.1016/j.sleep.2008.10.007. Epub 2009 Feb 4.

PMID:
19195928
6.

RLS and blood donation.

Burchell BJ, Allen RP, Miller JK, Hening WA, Earley CJ.

Sleep Med. 2009 Sep;10(8):844-9. doi: 10.1016/j.sleep.2008.09.013. Epub 2009 Jan 20.

PMID:
19157975
7.

Amino terminal domains of human UDP-glucuronosyltransferases (UGT) 2B7 and 2B15 associated with substrate selectivity and autoactivation.

Lewis BC, Mackenzie PI, Elliot DJ, Burchell B, Bhasker CR, Miners JO.

Biochem Pharmacol. 2007 May 1;73(9):1463-73. Epub 2006 Dec 22.

PMID:
17223084
8.
9.

Identification of the human liver UDP-glucuronosyltransferase involved in the metabolism of p-ethoxyphenylurea (dulcin).

Uesawa Y, Staines AG, Lockley D, Mohri K, Burchell B.

Arch Toxicol. 2007 Mar;81(3):163-8. Epub 2006 Aug 5.

PMID:
16897040
10.

Glucuronidation of SN-38 and NU/ICRF 505 in human colon cancer and adjacent normal colon.

Cummings J, Ethell BT, Jardine L, Burchell B.

Anticancer Res. 2006 May-Jun;26(3B):2189-96.

11.

Substrate specificity of human hepatic udp-glucuronosyltransferases.

Burchell B, Lockley DJ, Staines A, Uesawa Y, Coughtrie MW.

Methods Enzymol. 2005;400:46-57.

PMID:
16399342
12.

Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily.

Mackenzie PI, Bock KW, Burchell B, Guillemette C, Ikushiro S, Iyanagi T, Miners JO, Owens IS, Nebert DW.

Pharmacogenet Genomics. 2005 Oct;15(10):677-85. Review.

PMID:
16141793
13.
14.

Identification of the rabbit liver UDP-glucuronosyltransferase catalyzing the glucuronidation of 4-ethoxyphenylurea (dulcin).

Uesawa Y, Staines AG, O'Sullivan A, Mohri K, Burchell B.

Drug Metab Dispos. 2004 Dec;32(12):1476-81. Epub 2004 Sep 24.

PMID:
15448114
15.

Assessment of catechol induction and glucuronidation in rat liver microsomes.

Elovaara E, Mikkola J, Luukkanen L, Antonio L, Fournel-Gigleux S, Burchell B, Magdalou J, Taskinen J.

Drug Metab Dispos. 2004 Dec;32(12):1426-33. Epub 2004 Sep 15.

PMID:
15371300
16.

Evidence for multiple glucuronide transporters in rat liver microsomes.

Csala M, Staines AG, Bánhegyi G, Mandl J, Coughtrie MW, Burchell B.

Biochem Pharmacol. 2004 Oct 1;68(7):1353-62.

PMID:
15345325
17.

Farnesol is glucuronidated in human liver, kidney and intestine in vitro, and is a novel substrate for UGT2B7 and UGT1A1.

Staines AG, Sindelar P, Coughtrie MW, Burchell B.

Biochem J. 2004 Dec 15;384(Pt 3):637-45.

18.

N-glucuronidation of carbamazepine in human tissues is mediated by UGT2B7.

Staines AG, Coughtrie MW, Burchell B.

J Pharmacol Exp Ther. 2004 Dec;311(3):1131-7. Epub 2004 Aug 3.

PMID:
15292462
19.

Glucuronidation as a mechanism of intrinsic drug resistance in human colon cancer: reversal of resistance by food additives.

Cummings J, Ethell BT, Jardine L, Boyd G, Macpherson JS, Burchell B, Smyth JF, Jodrell DI.

Cancer Res. 2003 Dec 1;63(23):8443-50.

20.

Almokalant glucuronidation in human liver and kidney microsomes: evidence for the involvement of UGT1A9 and 2B7.

Gaiser BK, Lockley DJ, Staines AG, Baarnhielm C, Burchell B.

Xenobiotica. 2003 Nov;33(11):1073-83.

PMID:
14660172
21.
22.

Glucuronidation of HMR1098 in human microsomes: evidence for the involvement of UGT1A1 in the formation of S-glucuronides.

Ethell BT, Riedel J, Englert H, Jantz H, Oekonomopulos R, Burchell B.

Drug Metab Dispos. 2003 Aug;31(8):1027-34.

PMID:
12867491
23.

Treatment of restless legs syndrome with gabapentin: a double-blind, cross-over study.

Burchell BJ.

Neurology. 2003 May 13;60(9):1558; author reply 1558. No abstract available.

PMID:
12743261
24.

The effect of valproic acid on drug and steroid glucuronidation by expressed human UDP-glucuronosyltransferases.

Ethell BT, Anderson GD, Burchell B.

Biochem Pharmacol. 2003 May 1;65(9):1441-9.

PMID:
12732356
25.

Cloning and characterisation of the first drug-metabolising canine UDP-glucuronosyltransferase of the 2B subfamily.

Soars MG, Fettes M, O'Sullivan AC, Riley RJ, Ethell BT, Burchell B.

Biochem Pharmacol. 2003 Apr 15;65(8):1251-9.

PMID:
12694866
26.

MRP1-transfected cells do not show increased resistance against oxidative stress.

Balcerczyk A, Rychlik B, Kruszewski M, Burchell B, Bartosz G.

Free Radic Res. 2003 Feb;37(2):189-95.

PMID:
12653207
27.

Glucuronidation of catechols by human hepatic, gastric, and intestinal microsomal UDP-glucuronosyltransferases (UGT) and recombinant UGT1A6, UGT1A9, and UGT2B7.

Antonio L, Xu J, Little JM, Burchell B, Magdalou J, Radominska-Pandya A.

Arch Biochem Biophys. 2003 Mar 15;411(2):251-61.

PMID:
12623074
28.
29.

Glucuronidation of dihydroartemisinin in vivo and by human liver microsomes and expressed UDP-glucuronosyltransferases.

Ilett KF, Ethell BT, Maggs JL, Davis TM, Batty KT, Burchell B, Binh TQ, Thu le TA, Hung NC, Pirmohamed M, Park BK, Edwards G.

Drug Metab Dispos. 2002 Sep;30(9):1005-12.

PMID:
12167566
30.

Histone 2A stimulates glucose-6-phosphatase activity by permeabilization of liver microsomes.

Benedetti A, Fulceri R, Allan BB, Houston P, Sukhodub AL, Marcolongo P, Ethell B, Burchell B, Burchell A.

Biochem J. 2002 Oct 15;367(Pt 2):505-10.

31.

Quantitative structure activity relationships for the glucuronidation of simple phenols by expressed human UGT1A6 and UGT1A9.

Ethell BT, Ekins S, Wang J, Burchell B.

Drug Metab Dispos. 2002 Jun;30(6):734-8.

PMID:
12019203
32.

The importance of cysteine 126 in the human liver UDP-glucuronosyltransferase UGT1A6.

Senay C, Jedlitschky G, Terrier N, Burchell B, Magdalou J, Fournel-Gigleux S.

Biochim Biophys Acta. 2002 May 20;1597(1):90-6.

PMID:
12009407
33.

Tissue-specific regulation of canine intestinal and hepatic phenol and morphine UDP-glucuronosyltransferases by beta-naphthoflavone in comparison with humans.

Bock KW, Bock-Hennig BS, Münzel PA, Brandenburg JO, Köhle CT, Soars MG, Riley RJ, Burchell B, von Richter O, Eichelbaum MF, Swedmark S, Orzechowski A.

Biochem Pharmacol. 2002 May 1;63(9):1683-90.

PMID:
12007571
34.

Enhanced clearance of topoisomerase I inhibitors from human colon cancer cells by glucuronidation.

Cummings J, Boyd G, Ethell BT, Macpherson JS, Burchell B, Smyth JF, Jodrell DI.

Biochem Pharmacol. 2002 Feb 15;63(4):607-13.

PMID:
11992628
35.

In vitro analysis of human drug glucuronidation and prediction of in vivo metabolic clearance.

Soars MG, Burchell B, Riley RJ.

J Pharmacol Exp Ther. 2002 Apr;301(1):382-90.

PMID:
11907196
36.

Ethanol-dependent induction of bilirubin UDP-glucuronosyl-transferase in rat liver is mediated by Kupffer cells.

Kardon T, Mile V, Bánhegyi G, Csala M, Burchell B, Mandl J, Braun L.

Life Sci. 2002 Jan 25;70(10):1205-12.

PMID:
11848303
37.

Characterization of catechol glucuronidation in rat liver.

Antonio L, Grillasca JP, Taskinen J, Elovaara E, Burchell B, Piet MH, Ethell B, Ouzzine M, Fournel-Gigleux S, Magdalou J.

Drug Metab Dispos. 2002 Feb;30(2):199-207.

PMID:
11792691
38.

Evaluation of the marmoset as a model species for drug glucuronidation.

Soars MG, Riley RJ, Burchell B.

Xenobiotica. 2001 Dec;31(12):849-60.

PMID:
11780760
39.

Cloning and characterization of a canine UDP-glucuronosyltransferase.

Soars MG, Smith DJ, Riley RJ, Burchell B.

Arch Biochem Biophys. 2001 Jul 15;391(2):218-24.

PMID:
11437353
40.

Bile bilirubin pigment analysis in disorders of bilirubin metabolism in early infancy.

Lee WS, McKiernan PJ, Beath SV, Preece MA, Baty D, Kelly DA, Burchell B, Clarke DJ.

Arch Dis Child. 2001 Jul;85(1):38-42.

41.
42.

Characterisation of glucuronidation and transport in V79 cells co-expressing UGT1A1 and MRP1.

Cuff RL, Wade LT, Rychlik B, Jedlitschky GA, Burchell B.

Toxicol Lett. 2001 Mar 31;120(1-3):43-9.

PMID:
11323160
43.

Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank.

Fisher MB, Vandenbranden M, Findlay K, Burchell B, Thummel KE, Hall SD, Wrighton SA.

Pharmacogenetics. 2000 Nov;10(8):727-39.

PMID:
11186135
44.

Evidence for significant differences in microsomal drug glucuronidation by canine and human liver and kidney.

Soars MG, Riley RJ, Findlay KA, Coffey MJ, Burchell B.

Drug Metab Dispos. 2001 Feb;29(2):121-6.

PMID:
11159800
45.
46.

Importance of histidine residues for the function of the human liver UDP-glucuronosyltransferase UGT1A6: evidence for the catalytic role of histidine 370.

Ouzzine M, Antonio L, Burchell B, Netter P, Fournel-Gigleux S, Magdalou J.

Mol Pharmacol. 2000 Dec;58(6):1609-15.

PMID:
11093802
47.

Transcriptional induction of bilirubin UDP-glucuronosyltransrase by ethanol in rat liver.

Kardon T, Coffey MJ, Bánhegyi G, Conley AA, Burchell B, Mandl J, Braun L.

Alcohol. 2000 Jul;21(3):251-7.

PMID:
11091029
48.

Production of human UDP-glucuronosyltransferases 1A6 and 1A9 using the Semliki Forest virus expression system.

Forsman T, Lautala P, Lundström K, Monastyrskaia K, Ouzzine M, Burchell B, Taskinen J, Ulmanen I.

Life Sci. 2000 Oct 6;67(20):2473-84.

PMID:
11065170
49.

The specificity of glucuronidation of entacapone and tolcapone by recombinant human UDP-glucuronosyltransferases.

Lautala P, Ethell BT, Taskinen J, Burchell B.

Drug Metab Dispos. 2000 Nov;28(11):1385-9.

PMID:
11038168
50.

Characterization of the uridine diphosphate-glucuronosyltransferase-catalyzing thyroid hormone glucuronidation in man.

Findlay KA, Kaptein E, Visser TJ, Burchell B.

J Clin Endocrinol Metab. 2000 Aug;85(8):2879-83.

PMID:
10946897

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