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Items: 1 to 50 of 86

1.

BET bromodomain inhibition blocks the function of a critical AR-independent master regulator network in lethal prostate cancer.

Coleman DJ, Gao L, King CJ, Schwartzman J, Urrutia J, Sehrawat A, Tayou J, Balter A, Burchard J, Chiotti KE, Derrick DS, Sun D, Xia Z, Heiser LM, Alumkal JJ.

Oncogene. 2019 Jul;38(28):5658-5669. doi: 10.1038/s41388-019-0815-5. Epub 2019 Apr 17.

PMID:
30996246
2.

Intratracheal Administration of siRNA Triggers mRNA Silencing in the Lung to Modulate T Cell Immune Response and Lung Inflammation.

Ng B, Cash-Mason T, Wang Y, Seitzer J, Burchard J, Brown D, Dudkin V, Davide J, Jadhav V, Sepp-Lorenzino L, Cejas PJ.

Mol Ther Nucleic Acids. 2019 Jun 7;16:194-205. doi: 10.1016/j.omtn.2019.02.013. Epub 2019 Feb 26.

3.

Maintenance of MYC expression promotes de novo resistance to BET bromodomain inhibition in castration-resistant prostate cancer.

Coleman DJ, Gao L, Schwartzman J, Korkola JE, Sampson D, Derrick DS, Urrutia J, Balter A, Burchard J, King CJ, Chiotti KE, Heiser LM, Alumkal JJ.

Sci Rep. 2019 Mar 7;9(1):3823. doi: 10.1038/s41598-019-40518-5.

4.

Development of the Metabolic Syndrome: Study Design and Baseline Data of the Lufthansa Prevention Study (LUPS), A Prospective Observational Cohort Survey.

Müller-Wieland D, Altenburg C, Becher H, Burchard J, Frisch A, Gebhard J, Haas J, Harth V, Heeren J, Hengelbrock J, von Karais M, Knebel B, Kotzka J, Löwe B, Marx N, Pinnschmidt H, Preisser A, Rose M, Sawitzky-Rose B, Scheja L, Terschüren C, Töller M, Vettorazzi E, Wegscheider K.

Exp Clin Endocrinol Diabetes. 2018 Nov 26. doi: 10.1055/a-0767-6361. [Epub ahead of print]

PMID:
30477037
5.

Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival.

Gast CE, Silk AD, Zarour L, Riegler L, Burkhart JG, Gustafson KT, Parappilly MS, Roh-Johnson M, Goodman JR, Olson B, Schmidt M, Swain JR, Davies PS, Shasthri V, Iizuka S, Flynn P, Watson S, Korkola J, Courtneidge SA, Fischer JM, Jaboin J, Billingsley KG, Lopez CD, Burchard J, Gray J, Coussens LM, Sheppard BC, Wong MH.

Sci Adv. 2018 Sep 12;4(9):eaat7828. doi: 10.1126/sciadv.aat7828. eCollection 2018 Sep.

6.

Can Listeners Hear Who Is Singing? The Development of Voice Category Perception.

Erickson ML, Burchard J, Phillips P.

J Voice. 2018 Jul;32(4):459-465. doi: 10.1016/j.jvoice.2017.06.016. Epub 2018 Mar 2.

PMID:
29503102
7.

Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry.

Rizvi NF, Howe JA, Nahvi A, Klein DJ, Fischmann TO, Kim HY, McCoy MA, Walker SS, Hruza A, Richards MP, Chamberlin C, Saradjian P, Butko MT, Mercado G, Burchard J, Strickland C, Dandliker PJ, Smith GF, Nickbarg EB.

ACS Chem Biol. 2018 Mar 16;13(3):820-831. doi: 10.1021/acschembio.7b01013. Epub 2018 Feb 14.

PMID:
29412640
8.

Mycotoxins in dry-cured meats: A review.

Pizzolato Montanha F, Anater A, Burchard JF, Luciano FB, Meca G, Manyes L, Pimpão CT.

Food Chem Toxicol. 2018 Jan;111:494-502. doi: 10.1016/j.fct.2017.12.008. Epub 2017 Dec 5. Review.

PMID:
29217267
9.

Vitamin C Prevents Offspring DNA Methylation Changes Associated with Maternal Smoking in Pregnancy.

Shorey-Kendrick LE, McEvoy CT, Ferguson B, Burchard J, Park BS, Gao L, Vuylsteke BH, Milner KF, Morris CD, Spindel ER.

Am J Respir Crit Care Med. 2017 Sep 15;196(6):745-755. doi: 10.1164/rccm.201610-2141OC.

10.

Physiologically activated mammary fibroblasts promote postpartum mammary cancer.

Guo Q, Minnier J, Burchard J, Chiotti K, Spellman P, Schedin P.

JCI Insight. 2017 Mar 23;2(6):e89206. doi: 10.1172/jci.insight.89206.

11.

Assessment of roles for the Rho-specific guanine nucleotide dissociation inhibitor Ly-GDI in platelet function: a spatial systems approach.

Ngo AT, Thierheimer ML, Babur Ö, Rocheleau AD, Huang T, Pang J, Rigg RA, Mitrugno A, Theodorescu D, Burchard J, Nan X, Demir E, McCarty OJ, Aslan JE.

Am J Physiol Cell Physiol. 2017 Apr 1;312(4):C527-C536. doi: 10.1152/ajpcell.00274.2016. Epub 2017 Feb 1.

12.

The genome as pharmacopeia: association of genetic dose with phenotypic response.

Wadhawan S, Runz H, Burchard J.

Biochem Pharmacol. 2015 Apr 15;94(4):229-40. doi: 10.1016/j.bcp.2015.02.005. Epub 2015 Feb 20. Review.

PMID:
25707983
13.

A single dose of EGLN1 siRNA yields increased erythropoiesis in nonhuman primates.

Abrams MT, Koser M, Burchard J, Strapps W, Mehmet H, Gindy M, Zaller D, Sepp-Lorenzino L, Stickens D.

Nucleic Acid Ther. 2014 Dec;24(6):405-12. doi: 10.1089/nat.2014.0495.

PMID:
25272050
14.

Assessing unintended hybridization-induced biological effects of oligonucleotides.

Lindow M, Vornlocher HP, Riley D, Kornbrust DJ, Burchard J, Whiteley LO, Kamens J, Thompson JD, Nochur S, Younis H, Bartz S, Parry J, Ferrari N, Henry SP, Levin AA.

Nat Biotechnol. 2012 Oct;30(10):920-3. doi: 10.1038/nbt.2376. No abstract available.

PMID:
23051805
15.

siRNA off-target effects in genome-wide screens identify signaling pathway members.

Buehler E, Khan AA, Marine S, Rajaram M, Bahl A, Burchard J, Ferrer M.

Sci Rep. 2012;2:428. doi: 10.1038/srep00428. Epub 2012 May 29.

16.

Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting.

Lamb JR, Zhang C, Xie T, Wang K, Zhang B, Hao K, Chudin E, Fraser HB, Millstein J, Ferguson M, Suver C, Ivanovska I, Scott M, Philippar U, Bansal D, Zhang Z, Burchard J, Smith R, Greenawalt D, Cleary M, Derry J, Loboda A, Watters J, Poon RT, Fan ST, Yeung C, Lee NP, Guinney J, Molony C, Emilsson V, Buser-Doepner C, Zhu J, Friend S, Mao M, Shaw PM, Dai H, Luk JM, Schadt EE.

PLoS One. 2011;6(7):e20090. doi: 10.1371/journal.pone.0020090. Epub 2011 Jul 5.

17.

DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival.

Luk JM, Burchard J, Zhang C, Liu AM, Wong KF, Shek FH, Lee NP, Fan ST, Poon RT, Ivanovska I, Philippar U, Cleary MA, Buser CA, Shaw PM, Lee CN, Tenen DG, Dai H, Mao M.

J Biol Chem. 2011 Sep 2;286(35):30706-13. doi: 10.1074/jbc.M111.229831. Epub 2011 Jul 7.

18.

Gene expression signature of c-MYC-immortalized human fibroblasts reveals loss of growth inhibitory response to TGFβ.

Wang ML, Walsh R, Robinson KL, Burchard J, Bartz SR, Cleary M, Galloway DA, Grandori C.

Cell Cycle. 2011 Aug 1;10(15):2540-8. Epub 2011 Aug 1.

19.

RNA-induced silencing complex-bound small interfering RNA is a determinant of RNA interference-mediated gene silencing in mice.

Wei J, Jones J, Kang J, Card A, Krimm M, Hancock P, Pei Y, Ason B, Payson E, Dubinina N, Cancilla M, Stroh M, Burchard J, Sachs AB, Hochman JH, Flanagan WM, Kuklin NA.

Mol Pharmacol. 2011 Jun;79(6):953-63. doi: 10.1124/mol.110.070409. Epub 2011 Mar 22.

PMID:
21427169
20.

Global regulation on microRNA in hepatitis B virus-associated hepatocellular carcinoma.

Liu AM, Zhang C, Burchard J, Fan ST, Wong KF, Dai H, Poon RT, Luk JM.

OMICS. 2011 Mar;15(3):187-91. doi: 10.1089/omi.2010.0098. Epub 2011 Feb 14.

PMID:
21319996
21.

microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma.

Burchard J, Zhang C, Liu AM, Poon RT, Lee NP, Wong KF, Sham PC, Lam BY, Ferguson MD, Tokiwa G, Smith R, Leeson B, Beard R, Lamb JR, Lim L, Mao M, Dai H, Luk JM.

Mol Syst Biol. 2010 Aug 24;6:402. doi: 10.1038/msb.2010.58.

22.

MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT.

Zhang Z, Sun H, Dai H, Walsh RM, Imakura M, Schelter J, Burchard J, Dai X, Chang AN, Diaz RL, Marszalek JR, Bartz SR, Carleton M, Cleary MA, Linsley PS, Grandori C.

Cell Cycle. 2009 Sep 1;8(17):2756-68. Epub 2009 Sep 29.

PMID:
19652553
23.

MicroRNA-like off-target transcript regulation by siRNAs is species specific.

Burchard J, Jackson AL, Malkov V, Needham RH, Tan Y, Bartz SR, Dai H, Sachs AB, Linsley PS.

RNA. 2009 Feb;15(2):308-15. doi: 10.1261/rna.1326809.

24.

MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators.

Gabriely G, Wurdinger T, Kesari S, Esau CC, Burchard J, Linsley PS, Krichevsky AM.

Mol Cell Biol. 2008 Sep;28(17):5369-80. doi: 10.1128/MCB.00479-08. Epub 2008 Jun 30.

25.

MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression.

Ivanovska I, Ball AS, Diaz RL, Magnus JF, Kibukawa M, Schelter JM, Kobayashi SV, Lim L, Burchard J, Jackson AL, Linsley PS, Cleary MA.

Mol Cell Biol. 2008 Apr;28(7):2167-74. doi: 10.1128/MCB.01977-07. Epub 2008 Jan 22.

26.

Exposure of pregnant dairy heifer to magnetic fields at 60 Hz and 30 microT.

Burchard JF, Nguyen DH, Monardes HG.

Bioelectromagnetics. 2007 Sep;28(6):471-6.

PMID:
17492762
27.

Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies.

Kittler R, Surendranath V, Heninger AK, Slabicki M, Theis M, Putz G, Franke K, Caldarelli A, Grabner H, Kozak K, Wagner J, Rees E, Korn B, Frenzel C, Sachse C, Sönnichsen B, Guo J, Schelter J, Burchard J, Linsley PS, Jackson AL, Habermann B, Buchholz F.

Nat Methods. 2007 Apr;4(4):337-44. Epub 2007 Mar 11.

PMID:
17351622
28.

Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression.

Linsley PS, Schelter J, Burchard J, Kibukawa M, Martin MM, Bartz SR, Johnson JM, Cummins JM, Raymond CK, Dai H, Chau N, Cleary M, Jackson AL, Carleton M, Lim L.

Mol Cell Biol. 2007 Mar;27(6):2240-52. Epub 2007 Jan 22.

29.

LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.

Majercak J, Ray WJ, Espeseth A, Simon A, Shi XP, Wolffe C, Getty K, Marine S, Stec E, Ferrer M, Strulovici B, Bartz S, Gates A, Xu M, Huang Q, Ma L, Shughrue P, Burchard J, Colussi D, Pietrak B, Kahana J, Beher D, Rosahl T, Shearman M, Hazuda D, Sachs AB, Koblan KS, Seabrook GR, Stone DJ.

Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17967-72. Epub 2006 Nov 10.

30.

Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions.

Bartz SR, Zhang Z, Burchard J, Imakura M, Martin M, Palmieri A, Needham R, Guo J, Gordon M, Chung N, Warrener P, Jackson AL, Carleton M, Oatley M, Locco L, Santini F, Smith T, Kunapuli P, Ferrer M, Strulovici B, Friend SH, Linsley PS.

Mol Cell Biol. 2006 Dec;26(24):9377-86. Epub 2006 Sep 25.

31.

A genome wide analysis of ubiquitin ligases in APP processing identifies a novel regulator of BACE1 mRNA levels.

Espeseth AS, Huang Q, Gates A, Xu M, Yu Y, Simon AJ, Shi XP, Zhang X, Hodor P, Stone DJ, Burchard J, Cavet G, Bartz S, Linsley P, Ray WJ, Hazuda D.

Mol Cell Neurosci. 2006 Nov;33(3):227-35. Epub 2006 Sep 15.

PMID:
16978875
32.

Designing siRNA that distinguish between genes that differ by a single nucleotide.

Schwarz DS, Ding H, Kennington L, Moore JT, Schelter J, Burchard J, Linsley PS, Aronin N, Xu Z, Zamore PD.

PLoS Genet. 2006 Sep 8;2(9):e140. Epub 2006 Jul 24.

33.

Plasma concentrations of thyroxine in dairy cows exposed to 60 Hz electric and magnetic fields.

Burchard JF, Nguyen DH, Rodriguez M.

Bioelectromagnetics. 2006 Oct;27(7):553-9.

PMID:
16724328
34.

Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing.

Jackson AL, Burchard J, Leake D, Reynolds A, Schelter J, Guo J, Johnson JM, Lim L, Karpilow J, Nichols K, Marshall W, Khvorova A, Linsley PS.

RNA. 2006 Jul;12(7):1197-205. Epub 2006 May 8.

35.

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity.

Jackson AL, Burchard J, Schelter J, Chau BN, Cleary M, Lim L, Linsley PS.

RNA. 2006 Jul;12(7):1179-87. Epub 2006 May 8.

36.

Second-generation shRNA libraries covering the mouse and human genomes.

Silva JM, Li MZ, Chang K, Ge W, Golding MC, Rickles RJ, Siolas D, Hu G, Paddison PJ, Schlabach MR, Sheth N, Bradshaw J, Burchard J, Kulkarni A, Cavet G, Sachidanandam R, McCombie WR, Cleary MA, Elledge SJ, Hannon GJ.

Nat Genet. 2005 Nov;37(11):1281-8. Epub 2005 Oct 2.

PMID:
16200065
37.

Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis.

Cleary MA, Kilian K, Wang Y, Bradshaw J, Cavet G, Ge W, Kulkarni A, Paddison PJ, Chang K, Sheth N, Leproust E, Coffey EM, Burchard J, McCombie WR, Linsley P, Hannon GJ.

Nat Methods. 2004 Dec;1(3):241-8. Epub 2004 Nov 18.

PMID:
15782200
38.

Exposure chamber for determining the biological effects of electric and magnetic fields on dairy cows.

Nguyen DH, Richard L, Burchard JF.

Bioelectromagnetics. 2005 Feb;26(2):138-44.

PMID:
15672371
39.

Synthetic shRNAs as potent RNAi triggers.

Siolas D, Lerner C, Burchard J, Ge W, Linsley PS, Paddison PJ, Hannon GJ, Cleary MA.

Nat Biotechnol. 2005 Feb;23(2):227-31. Epub 2004 Dec 26.

PMID:
15619616
40.

Blood melatonin and prolactin concentrations in dairy cows exposed to 60 Hz electric and magnetic fields during 8 h photoperiods.

Rodriguez M, Petitclerc D, Burchard JF, Nguyen DH, Block E.

Bioelectromagnetics. 2004 Oct;25(7):508-15.

PMID:
15376244
41.

T lymphocyte activation gene identification by coregulated expression on DNA microarrays.

Mao M, Biery MC, Kobayashi SV, Ward T, Schimmack G, Burchard J, Schelter JM, Dai H, He YD, Linsley PS.

Genomics. 2004 Jun;83(6):989-99.

PMID:
15177553
42.

Lack of effect of 10 kV/m 60 Hz electric field exposure on pregnant dairy heifer hormones.

Burchard JF, Nguyen DH, Monardes HG, Petitclerc D.

Bioelectromagnetics. 2004 May;25(4):308-12.

PMID:
15114640
43.
44.

Expression profiling reveals off-target gene regulation by RNAi.

Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, Mao M, Li B, Cavet G, Linsley PS.

Nat Biotechnol. 2003 Jun;21(6):635-7. Epub 2003 May 18.

PMID:
12754523
45.

Responses of the estrous cycle in dairy cows exposed to electric and magnetic fields (60 Hz) during 8-h photoperiods.

Rodriguez M, Petitclerc D, Burchard JF, Nguyen DH, Block E, Downey BR.

Anim Reprod Sci. 2003 May 15;77(1-2):11-20.

PMID:
12654524
47.

Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors.

Riley JL, Mao M, Kobayashi S, Biery M, Burchard J, Cavet G, Gregson BP, June CH, Linsley PS.

Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11790-5. Epub 2002 Aug 23.

48.

Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer.

Hughes TR, Mao M, Jones AR, Burchard J, Marton MJ, Shannon KW, Lefkowitz SM, Ziman M, Schelter JM, Meyer MR, Kobayashi S, Davis C, Dai H, He YD, Stephaniants SB, Cavet G, Walker WL, West A, Coffey E, Shoemaker DD, Stoughton R, Blanchard AP, Friend SH, Linsley PS.

Nat Biotechnol. 2001 Apr;19(4):342-7.

PMID:
11283592
49.

Experimental annotation of the human genome using microarray technology.

Shoemaker DD, Schadt EE, Armour CD, He YD, Garrett-Engele P, McDonagh PD, Loerch PM, Leonardson A, Lum PY, Cavet G, Wu LF, Altschuler SJ, Edwards S, King J, Tsang JS, Schimmack G, Schelter JM, Koch J, Ziman M, Marton MJ, Li B, Cundiff P, Ward T, Castle J, Krolewski M, Meyer MR, Mao M, Burchard J, Kidd MJ, Dai H, Phillips JW, Linsley PS, Stoughton R, Scherer S, Boguski MS.

Nature. 2001 Feb 15;409(6822):922-7.

PMID:
11237012
50.

Widespread aneuploidy revealed by DNA microarray expression profiling.

Hughes TR, Roberts CJ, Dai H, Jones AR, Meyer MR, Slade D, Burchard J, Dow S, Ward TR, Kidd MJ, Friend SH, Marton MJ.

Nat Genet. 2000 Jul;25(3):333-7.

PMID:
10888885

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