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Items: 1 to 50 of 316

1.

Dissection of immune gene networks in primary melanoma tumors critical for antitumor surveillance of patients with stage II-III resectable disease.

Sivendran S, Chang R, Pham L, Phelps RG, Harcharik ST, Hall LD, Bernardo SG, Moskalenko MM, Sivendran M, Fu Y, de Moll EH, Pan M, Moon JY, Arora S, Cohain A, DiFeo A, Ferringer TC, Tismenetsky M, Tsui CL, Friedlander PA, Parides MK, Banchereau J, Chaussabel D, Lebwohl MG, Wolchok JD, Bhardwaj N, Burakoff SJ, Oh WK, Palucka K, Merad M, Schadt EE, Saenger YM.

J Invest Dermatol. 2014 Aug;134(8):2202-2211. doi: 10.1038/jid.2014.85. Epub 2014 Feb 12.

2.

Identification of a novel binding site between HIV type 1 Nef C-terminal flexible loop and AP2 required for Nef-mediated CD4 downregulation.

Jin YJ, Cai CY, Mezei M, Ohlmeyer M, Sanchez R, Burakoff SJ.

AIDS Res Hum Retroviruses. 2013 Apr;29(4):725-31. doi: 10.1089/AID.2012.0286. Epub 2012 Dec 31.

3.

A remembrance of Baruj Benacerraf (AAI '57) 1920-2011.

Germain RN, Burakoff SJ.

J Immunol. 2011 Dec 1;187(11):5465-9. doi: 10.4049/jimmunol.1190069. No abstract available.

4.

CD43 regulates the threshold for T cell activation by targeting Cbl functions.

Pedraza-Alva G, Mérida LB, del Rio R, Fierro NA, Cruz-Muñoz ME, Olivares N, Melchy E, Igras V, Holländer GA, Burakoff SJ, Rosenstein Y.

IUBMB Life. 2011 Oct;63(10):940-8. doi: 10.1002/iub.554. Epub 2011 Sep 9.

5.

Non-invasive in vivo imaging for liver tumour progression using an orthotopic hepatocellular carcinoma model in immunocompetent mice.

Wang Q, Luan W, Goz V, Burakoff SJ, Hiotis SP.

Liver Int. 2011 Sep;31(8):1200-8. doi: 10.1111/j.1478-3231.2011.02523.x. Epub 2011 Apr 11.

PMID:
21745281
6.

Two sorting motifs, a ubiquitination motif and a tyrosine motif, are involved in HIV-1 and simian immunodeficiency virus Nef-mediated receptor endocytosis.

Cai CY, Zhang X, Sinko PJ, Burakoff SJ, Jin YJ.

J Immunol. 2011 May 15;186(10):5807-14. doi: 10.4049/jimmunol.1003506. Epub 2011 Apr 11.

7.

Cancer therapy from bench to bedside.

Oh WK, Burakoff SJ.

Mt Sinai J Med. 2010 Nov-Dec;77(6):571-2. doi: 10.1002/msj.20221. No abstract available.

PMID:
21105120
8.

Alkylating HIV-1 Nef - a potential way of HIV intervention.

Jin YJ, Zhang X, Cai CY, Burakoff SJ.

AIDS Res Ther. 2010 Jul 26;7:26. doi: 10.1186/1742-6405-7-26.

9.

Interleukin-3 (IL-3)-induced c-fos activation is modulated by Gab2-calcineurin interaction.

Pyarajan S, Matejovic G, Pratt JC, Baksh S, Burakoff SJ.

J Biol Chem. 2008 Aug 29;283(35):23505-9. doi: 10.1074/jbc.C800087200. Epub 2008 Jun 27.

10.

Lysine 144, a ubiquitin attachment site in HIV-1 Nef, is required for Nef-mediated CD4 down-regulation.

Jin YJ, Cai CY, Zhang X, Burakoff SJ.

J Immunol. 2008 Jun 15;180(12):7878-86.

11.

Prostaglandin E2 activates HPK1 kinase activity via a PKA-dependent pathway.

Sawasdikosol S, Pyarajan S, Alzabin S, Matejovic G, Burakoff SJ.

J Biol Chem. 2007 Nov 30;282(48):34693-9. Epub 2007 Sep 25.

12.

From bytes to bedside: data integration and computational biology for translational cancer research.

Mathew JP, Taylor BS, Bader GD, Pyarajan S, Antoniotti M, Chinnaiyan AM, Sander C, Burakoff SJ, Mishra B.

PLoS Comput Biol. 2007 Feb 23;3(2):e12. Review. No abstract available.

13.

A CD8/Lck transgene is able to drive thymocyte differentiation.

Fragoso RC, Pyarajan S, Irie HY, Burakoff SJ.

J Immunol. 2006 Nov 1;177(9):6007-17.

14.

HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent.

Jin YJ, Cai CY, Zhang X, Zhang HT, Hirst JA, Burakoff SJ.

J Immunol. 2005 Sep 1;175(5):3157-64. Erratum in: J Immunol. 2006 Feb 15;176(4):2669.

15.

CD4 phosphorylation partially reverses Nef down-regulation of CD4.

Jin YJ, Zhang X, Boursiquot JG, Burakoff SJ.

J Immunol. 2004 Nov 1;173(9):5495-500.

16.

Fratricide of CD8+ cytotoxic T lymphocytes is dependent on cellular activation and perforin-mediated killing.

Su MW, Pyarajan S, Chang JH, Yu CL, Jin YJ, Stierhof YD, Walden P, Burakoff SJ.

Eur J Immunol. 2004 Sep;34(9):2459-70.

17.

Nicotine activates nuclear factor of activated T cells c2 (NFATc2) and prevents cell cycle entry in T cells.

Frazer-Abel AA, Baksh S, Fosmire SP, Willis D, Pierce AM, Meylemans H, Linthicum DS, Burakoff SJ, Coons T, Bellgrau D, Modiano JF.

J Pharmacol Exp Ther. 2004 Nov;311(2):758-69. Epub 2004 Jul 1.

PMID:
15231866
18.

Increasing T-cell age reduces effector activity but preserves proliferative capacity in a murine allogeneic major histocompatibility complex-mismatched bone marrow transplant model.

Friedman JS, Alpdogan O, van den Brink MR, Liu C, Hurwitz D, Boyd A, Kupper TS, Burakoff SJ.

Biol Blood Marrow Transplant. 2004 Jul;10(7):448-60.

19.

SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness.

Friedman JS, Lopez MF, Fleming MD, Rivera A, Martin FM, Welsh ML, Boyd A, Doctrow SR, Burakoff SJ.

Blood. 2004 Oct 15;104(8):2565-73. Epub 2004 Jun 17.

PMID:
15205258
21.

Hematopoietic progenitor kinase 1 (HPK1) negatively regulates prostaglandin E2-induced fos gene transcription.

Sawasdikosol S, Russo KM, Burakoff SJ.

Blood. 2003 May 1;101(9):3687-9. Epub 2003 Jan 9.

PMID:
12522005
23.

NFATc2-mediated repression of cyclin-dependent kinase 4 expression.

Baksh S, Widlund HR, Frazer-Abel AA, Du J, Fosmire S, Fisher DE, DeCaprio JA, Modiano JF, Burakoff SJ.

Mol Cell. 2002 Nov;10(5):1071-81.

24.

Effect of anti-IL-2Ralpha antibody on IL-2-induced Jak/STAT signaling.

Tkaczuk J, Yu CL, Baksh S, Milford EL, Carpenter CB, Burakoff SJ, McKay DB.

Am J Transplant. 2002 Jan;2(1):31-40.

25.

Cytolytic pathways in haematopoietic stem-cell transplantation.

van den Brink MR, Burakoff SJ.

Nat Rev Immunol. 2002 Apr;2(4):273-81. Review.

PMID:
12001998
26.

Enhanced allostimulatory activity of host antigen-presenting cells in old mice intensifies acute graft-versus-host disease.

Ordemann R, Hutchinson R, Friedman J, Burakoff SJ, Reddy P, Duffner U, Braun TM, Liu C, Teshima T, Ferrara JL.

J Clin Invest. 2002 May;109(9):1249-56.

27.

Wnt-1 and Wnt-4 regulate thymic cellularity.

Mulroy T, McMahon JA, Burakoff SJ, McMahon AP, Sen J.

Eur J Immunol. 2002 Apr;32(4):967-71.

28.

Differential use of Fas ligand and perforin cytotoxic pathways by donor T cells in graft-versus-host disease and graft-versus-leukemia effect.

Schmaltz C, Alpdogan O, Horndasch KJ, Muriglan SJ, Kappel BJ, Teshima T, Ferrara JL, Burakoff SJ, van den Brink MR.

Blood. 2001 May 1;97(9):2886-95.

PMID:
11313285
29.

Absence of mitochondrial superoxide dismutase results in a murine hemolytic anemia responsive to therapy with a catalytic antioxidant.

Friedman JS, Rebel VI, Derby R, Bell K, Huang TT, Kuypers FA, Epstein CJ, Burakoff SJ.

J Exp Med. 2001 Apr 16;193(8):925-34.

30.
31.
32.

A peptide library approach identifies a specific inhibitor for the ZAP-70 protein tyrosine kinase.

Nishikawa K, Sawasdikosol S, Fruman DA, Lai J, Songyang Z, Burakoff SJ, Yaffe MB, Cantley LC.

Mol Cell. 2000 Oct;6(4):969-74.

33.

Cutting edge: gab2 mediates an inhibitory phosphatidylinositol 3'-kinase pathway in T cell antigen receptor signaling.

Pratt JC, Igras VE, Maeda H, Baksh S, Gelfand EW, Burakoff SJ, Neel BG, Gu H.

J Immunol. 2000 Oct 15;165(8):4158-63.

34.

Regulation of Cbl molecular interactions by the co-receptor molecule CD43 in human T cells.

Pedraza-Alva G, Sawasdikosol S, Liu YC, Mérida LB, Cruz-Muñoz ME, Oceguera-Yañez F, Burakoff SJ, Rosenstein Y.

J Biol Chem. 2001 Jan 5;276(1):729-37.

35.

Adapting to multiple personalities: Cbl is also a RING finger ubiquitin ligase.

Sawasdikosol S, Pratt JC, Meng W, Eck MJ, Burakoff SJ.

Biochim Biophys Acta. 2000 Jul 31;1471(1):M1-M12. Review. No abstract available.

PMID:
11004605
36.

The role of calcineurin in lymphocyte activation.

Baksh S, Burakoff SJ.

Semin Immunol. 2000 Aug;12(4):405-15. Review.

PMID:
10995587
37.

Fas ligand-deficient gld mice are more susceptible to graft-versus-host-disease.

van den Brink MR, Moore E, Horndasch KJ, Crawford JM, Murphy GF, Burakoff SJ.

Transplantation. 2000 Jul 15;70(1):184-91.

PMID:
10919598
38.

CD43-mediated signals induce DNA binding activity of AP-1, NF-AT, and NFkappa B transcription factors in human T lymphocytes.

Santana MA, Pedraza-Alva G, Olivares-Zavaleta N, Madrid-Marina V, Horejsi V, Burakoff SJ, Rosenstein Y.

J Biol Chem. 2000 Oct 6;275(40):31460-8.

39.

Calcineurin regulation of the mammalian G0/G1 checkpoint element, cyclin dependent kinase 4.

Baksh S, DeCaprio JA, Burakoff SJ.

Oncogene. 2000 Jun 1;19(24):2820-7.

40.

Graft-versus-host-disease-associated thymic damage results in the appearance of T cell clones with anti-host reactivity.

van den Brink MR, Moore E, Ferrara JL, Burakoff SJ.

Transplantation. 2000 Feb 15;69(3):446-9.

PMID:
10706060
41.

Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation.

Yu CL, Jin YJ, Burakoff SJ.

J Biol Chem. 2000 Jan 7;275(1):599-604.

42.

Fas-deficient lpr mice are more susceptible to graft-versus-host disease.

van Den Brink MR, Moore E, Horndasch KJ, Crawford JM, Hoffman J, Murphy GF, Burakoff SJ.

J Immunol. 2000 Jan 1;164(1):469-80.

43.

Antigen-induced unresponsiveness results in altered T cell signaling.

McKay DB, Irie HY, Hollander G, Ferrara JL, Strom TB, Li Y, Burakoff SJ.

J Immunol. 1999 Dec 15;163(12):6455-61.

44.
45.

Requirement for Shc in TCR-mediated activation of a T cell hybridoma.

Pratt JC, van den Brink MR, Igras VE, Walk SF, Ravichandran KS, Burakoff SJ.

J Immunol. 1999 Sep 1;163(5):2586-91.

46.

SLAP, a dimeric adapter protein, plays a functional role in T cell receptor signaling.

Tang J, Sawasdikosol S, Chang JH, Burakoff SJ.

Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9775-80.

47.

The extracellular signal-regulated kinase pathway is required for activation-induced cell death of T cells.

van den Brink MR, Kapeller R, Pratt JC, Chang JH, Burakoff SJ.

J Biol Chem. 1999 Apr 16;274(16):11178-85.

48.

Positive and negative signaling pathways.

Pratt JC, Sawasdikosol S, van den Brink MR, Burakoff SJ.

Transplant Proc. 1999 Feb-Mar;31(1-2):772-4. Review. No abstract available.

PMID:
10083327
49.

Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase.

Meng W, Sawasdikosol S, Burakoff SJ, Eck MJ.

Nature. 1999 Mar 4;398(6722):84-90.

PMID:
10078535

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