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Items: 46

1.

RIM is essential for stimulated but not spontaneous somatodendritic dopamine release in the midbrain.

Robinson BG, Cai X, Wang J, Bunzow JR, Williams JT, Kaeser PS.

Elife. 2019 Sep 5;8. pii: e47972. doi: 10.7554/eLife.47972.

2.

Cellular tolerance at the µ-opioid receptor is phosphorylation dependent.

Arttamangkul S, Heinz DA, Bunzow JR, Song X, Williams JT.

Elife. 2018 Mar 28;7. pii: e34989. doi: 10.7554/eLife.34989.

3.

Desensitized D2 autoreceptors are resistant to trafficking.

Robinson BG, Bunzow JR, Grimm JB, Lavis LD, Dudman JT, Brown J, Neve KA, Williams JT.

Sci Rep. 2017 Jun 29;7(1):4379. doi: 10.1038/s41598-017-04728-z.

4.

Distinct regulation of dopamine D2S and D2L autoreceptor signaling by calcium.

Gantz SC, Robinson BG, Buck DC, Bunzow JR, Neve RL, Williams JT, Neve KA.

Elife. 2015 Aug 26;4. doi: 10.7554/eLife.09358.

5.

Agonist Binding and Desensitization of the μ-Opioid Receptor Is Modulated by Phosphorylation of the C-Terminal Tail Domain.

Birdsong WT, Arttamangkul S, Bunzow JR, Williams JT.

Mol Pharmacol. 2015 Oct;88(4):816-24. doi: 10.1124/mol.114.097527. Epub 2015 May 1.

6.

Exploring the determinants of trace amine-associated receptor 1's functional selectivity for the stereoisomers of amphetamine and methamphetamine.

Reese EA, Norimatsu Y, Grandy MS, Suchland KL, Bunzow JR, Grandy DK.

J Med Chem. 2014 Jan 23;57(2):378-90. doi: 10.1021/jm401316v. Epub 2014 Jan 7.

PMID:
24354319
7.

Spontaneous inhibitory synaptic currents mediated by a G protein-coupled receptor.

Gantz SC, Bunzow JR, Williams JT.

Neuron. 2013 Jun 5;78(5):807-12. doi: 10.1016/j.neuron.2013.04.013.

8.

The molecular basis of species-specific ligand activation of trace amine-associated receptor 1 (TAAR(1)).

Tan ES, Naylor JC, Groban ES, Bunzow JR, Jacobson MP, Grandy DK, Scanlan TS.

ACS Chem Biol. 2009 Mar 20;4(3):209-20. doi: 10.1021/cb800304d.

9.

PCR cloning of neural gene products.

Grandy DK, Bunzow JR, Dorit RL.

Curr Protoc Neurosci. 2001 May;Chapter 4:Unit 4.2. doi: 10.1002/0471142301.ns0402s08.

PMID:
18428481
10.

Exploring the structure-activity relationship of the ethylamine portion of 3-iodothyronamine for rat and mouse trace amine-associated receptor 1.

Tan ES, Miyakawa M, Bunzow JR, Grandy DK, Scanlan TS.

J Med Chem. 2007 Jun 14;50(12):2787-98. Epub 2007 May 12.

PMID:
17497842
11.

Trace amine-associated receptor 1 displays species-dependent stereoselectivity for isomers of methamphetamine, amphetamine, and para-hydroxyamphetamine.

Reese EA, Bunzow JR, Arttamangkul S, Sonders MS, Grandy DK.

J Pharmacol Exp Ther. 2007 Apr;321(1):178-86. Epub 2007 Jan 11.

PMID:
17218486
12.

Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues.

Hart ME, Suchland KL, Miyakawa M, Bunzow JR, Grandy DK, Scanlan TS.

J Med Chem. 2006 Feb 9;49(3):1101-12.

PMID:
16451074
13.

Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors.

Lindemann L, Ebeling M, Kratochwil NA, Bunzow JR, Grandy DK, Hoener MC.

Genomics. 2005 Mar;85(3):372-85.

PMID:
15718104
14.

3-Iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone.

Scanlan TS, Suchland KL, Hart ME, Chiellini G, Huang Y, Kruzich PJ, Frascarelli S, Crossley DA, Bunzow JR, Ronca-Testoni S, Lin ET, Hatton D, Zucchi R, Grandy DK.

Nat Med. 2004 Jun;10(6):638-42. Epub 2004 May 16.

PMID:
15146179
15.

Association of dopamine D(3) receptors with actin-binding protein 280 (ABP-280).

Li M, Li C, Weingarten P, Bunzow JR, Grandy DK, Zhou QY.

Biochem Pharmacol. 2002 Mar 1;63(5):859-63.

PMID:
11911837
16.

Amphetamine, 3,4-methylenedioxymethamphetamine, lysergic acid diethylamide, and metabolites of the catecholamine neurotransmitters are agonists of a rat trace amine receptor.

Bunzow JR, Sonders MS, Arttamangkul S, Harrison LM, Zhang G, Quigley DI, Darland T, Suchland KL, Pasumamula S, Kennedy JL, Olson SB, Magenis RE, Amara SG, Grandy DK.

Mol Pharmacol. 2001 Dec;60(6):1181-8.

PMID:
11723224
17.

Dopamine D4 receptor-deficient mice display cortical hyperexcitability.

Rubinstein M, Cepeda C, Hurst RS, Flores-Hernandez J, Ariano MA, Falzone TL, Kozell LB, Meshul CK, Bunzow JR, Low MJ, Levine MS, Grandy DK.

J Neurosci. 2001 Jun 1;21(11):3756-63.

18.

Locomotor activity in D2 dopamine receptor-deficient mice is determined by gene dosage, genetic background, and developmental adaptations.

Kelly MA, Rubinstein M, Phillips TJ, Lessov CN, Burkhart-Kasch S, Zhang G, Bunzow JR, Fang Y, Gerhardt GA, Grandy DK, Low MJ.

J Neurosci. 1998 May 1;18(9):3470-9.

19.

Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine.

Rubinstein M, Phillips TJ, Bunzow JR, Falzone TL, Dziewczapolski G, Zhang G, Fang Y, Larson JL, McDougall JA, Chester JA, Saez C, Pugsley TA, Gershanik O, Low MJ, Grandy DK.

Cell. 1997 Sep 19;90(6):991-1001.

20.

Mu and delta opioids but not kappa opioid inhibit voltage-activated Ba2+ currents in neuronal F-11 cell.

Nah SY, Unteutsch A, Bunzow JR, Cook SP, Beacham DW, Grandy DK.

Brain Res. 1997 Aug 22;766(1-2):66-71.

PMID:
9359588
21.

Pituitary lactotroph hyperplasia and chronic hyperprolactinemia in dopamine D2 receptor-deficient mice.

Kelly MA, Rubinstein M, Asa SL, Zhang G, Saez C, Bunzow JR, Allen RG, Hnasko R, Ben-Jonathan N, Grandy DK, Low MJ.

Neuron. 1997 Jul;19(1):103-13.

22.

Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.

Reinscheid RK, Nothacker HP, Bourson A, Ardati A, Henningsen RA, Bunzow JR, Grandy DK, Langen H, Monsma FJ Jr, Civelli O.

Science. 1995 Nov 3;270(5237):792-4.

PMID:
7481766
23.

Functional characterization of the human dopamine D4.2 receptor using vaccinia virus as an expression system.

Bouvier C, Bunzow JR, Guan HC, Unteutsch A, Civelli O, Grandy DK, Van Tol HH.

Eur J Pharmacol. 1995 Jun 23;290(1):11-7.

PMID:
7664820
24.

Characterization and distribution of a cloned rat mu-opioid receptor.

Bunzow JR, Zhang G, Bouvier C, Saez C, Ronnekleiv OK, Kelly MJ, Grandy DK.

J Neurochem. 1995 Jan;64(1):14-24.

PMID:
7798908
25.

Dopamine D4 receptor repeat: analysis of different native and mutant forms of the human and rat genes.

Asghari V, Schoots O, van Kats S, Ohara K, Jovanovic V, Guan HC, Bunzow JR, Petronis A, Van Tol HH.

Mol Pharmacol. 1994 Aug;46(2):364-73.

PMID:
8078498
26.

Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type.

Bunzow JR, Saez C, Mortrud M, Bouvier C, Williams JT, Low M, Grandy DK.

FEBS Lett. 1994 Jun 27;347(2-3):284-8.

27.

The distribution of dopamine D2 receptor heteronuclear RNA (hnRNA) in the rat brain.

Fox CA, Mansour A, Thompson RC, Bunzow JR, Civelli O, Watson SJ Jr.

J Chem Neuroanat. 1993 Nov-Dec;6(6):363-73.

28.

Molecular diversity of the dopamine receptors.

Civelli O, Bunzow JR, Grandy DK.

Annu Rev Pharmacol Toxicol. 1993;33:281-307. Review. No abstract available.

PMID:
8494342
29.

Multiple dopamine D4 receptor variants in the human population.

Van Tol HH, Wu CM, Guan HC, Ohara K, Bunzow JR, Civelli O, Kennedy J, Seeman P, Niznik HB, Jovanovic V.

Nature. 1992 Jul 9;358(6382):149-52.

PMID:
1319557
30.

The diversity of the dopamine receptors.

Civelli O, Bunzow JR, Zhou QY, Grandy DK.

NIDA Res Monogr. 1992;126:23-33. Review. No abstract available.

PMID:
1491715
31.

Comparison of the distributions of D1 and D2 dopamine receptor mRNAs in rat brain.

Meador-Woodruff JH, Mansour A, Healy DJ, Kuehn R, Zhou QY, Bunzow JR, Akil H, Civelli O, Watson SJ Jr.

Neuropsychopharmacology. 1991 Dec;5(4):231-42.

PMID:
1839499
32.

Multiple human D5 dopamine receptor genes: a functional receptor and two pseudogenes.

Grandy DK, Zhang YA, Bouvier C, Zhou QY, Johnson RA, Allen L, Buck K, Bunzow JR, Salon J, Civelli O.

Proc Natl Acad Sci U S A. 1991 Oct 15;88(20):9175-9.

33.

Molecular biology of the dopamine receptors.

Civelli O, Bunzow JR, Grandy DK, Zhou QY, Van Tol HH.

Eur J Pharmacol. 1991 Aug 14;207(4):277-86. Review.

PMID:
1783000
34.

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine.

Van Tol HH, Bunzow JR, Guan HC, Sunahara RK, Seeman P, Niznik HB, Civelli O.

Nature. 1991 Apr 18;350(6319):610-4.

PMID:
1840645
35.

Regulation of responsiveness at D2 dopamine receptors by receptor desensitization and adenylyl cyclase sensitization.

Bates MD, Senogles SE, Bunzow JR, Liggett SB, Civelli O, Caron MG.

Mol Pharmacol. 1991 Jan;39(1):55-63.

PMID:
1846220
36.

Cloning and expression of human and rat D1 dopamine receptors.

Zhou QY, Grandy DK, Thambi L, Kushner JA, Van Tol HH, Cone R, Pribnow D, Salon J, Bunzow JR, Civelli O.

Nature. 1990 Sep 6;347(6288):76-80.

PMID:
2168520
37.

Molecular cloning and expression of the rat beta 1-adrenergic receptor gene.

Machida CA, Bunzow JR, Searles RP, Van Tol H, Tester B, Neve KA, Teal P, Nipper V, Civelli O.

J Biol Chem. 1990 Aug 5;265(22):12960-5.

38.
39.

Molecular characterization of dopamine receptors.

Bates MD, Gingrich JA, Bunzow JR, Falardeau P, Dearry A, Senogles SE, Civelli O, Caron MG.

Am J Hypertens. 1990 Jun;3(6 Pt 2):29S-33S. Review.

PMID:
2143386
40.

Cloning, functional expression, and mRNA tissue distribution of the rat 5-hydroxytryptamine1A receptor gene.

Albert PR, Zhou QY, Van Tol HH, Bunzow JR, Civelli O.

J Biol Chem. 1990 Apr 5;265(10):5825-32.

41.

Coupling of a cloned rat dopamine-D2 receptor to inhibition of adenylyl cyclase and prolactin secretion.

Albert PR, Neve KA, Bunzow JR, Civelli O.

J Biol Chem. 1990 Feb 5;265(4):2098-104.

42.

Cloning of the cDNA and gene for a human D2 dopamine receptor.

Grandy DK, Marchionni MA, Makam H, Stofko RE, Alfano M, Frothingham L, Fischer JB, Burke-Howie KJ, Bunzow JR, Server AC, et al.

Proc Natl Acad Sci U S A. 1989 Dec;86(24):9762-6.

43.

The human dopamine D2 receptor gene is located on chromosome 11 at q22-q23 and identifies a TaqI RFLP.

Grandy DK, Litt M, Allen L, Bunzow JR, Marchionni M, Makam H, Reed L, Magenis RE, Civelli O.

Am J Hum Genet. 1989 Nov;45(5):778-85.

44.

Distribution of D2 dopamine receptor mRNA in rat brain.

Meador-Woodruff JH, Mansour A, Bunzow JR, Van Tol HH, Watson SJ Jr, Civelli O.

Proc Natl Acad Sci U S A. 1989 Oct;86(19):7625-8.

45.

Functional characterization of a rat dopamine D-2 receptor cDNA expressed in a mammalian cell line.

Neve KA, Henningsen RA, Bunzow JR, Civelli O.

Mol Pharmacol. 1989 Sep;36(3):446-51.

PMID:
2571073
46.

Cloning and expression of a rat D2 dopamine receptor cDNA.

Bunzow JR, Van Tol HH, Grandy DK, Albert P, Salon J, Christie M, Machida CA, Neve KA, Civelli O.

Nature. 1988 Dec 22-29;336(6201):783-7.

PMID:
2974511

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