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Items: 1 to 50 of 213

1.

Intracerebroventricular enzyme replacement therapy with Beta-Galactosidase reverses brain pathologies due to GM1 gangliosidosis in mice.

Chen JC, Luu AR, Wise N, Angelis R, Agrawal V, Mangini L, Vincelette J, Handyside B, Sterling HJ, Lo MJ, Wong H, Galicia N, Pacheco G, Van Vleet J, Giaramita A, Fong S, Roy SM, Hague C, Lawrence R, Bullens S, Christianson TM, d'Azzo A, Crawford BE, Bunting S, Lebowitz JH, Yogalingam G.

J Biol Chem. 2019 Sep 3. pii: jbc.RA119.009811. doi: 10.1074/jbc.RA119.009811. [Epub ahead of print]

2.

Using a student-led, community-specific training module to increase PrEP uptake amongst at-risk populations: results from an exploratory pilot implementation.

Bunting SR, Saqueton R, Batteson TJ.

AIDS Care. 2019 Aug 26:1-5. doi: 10.1080/09540121.2019.1659916. [Epub ahead of print]

PMID:
31450953
3.

XLF extends its range from DNA repair to replication.

Gonzalez-Rodriguez Y, Bunting SF.

J Cell Biol. 2019 Jul 1;218(7):2075-2076. doi: 10.1083/jcb.201905221. Epub 2019 Jun 12.

PMID:
31189608
4.

A Guide for Designing Student-Led, Interprofessional Community Education Initiatives About HIV Risk and Pre-Exposure Prophylaxis.

Bunting SR, Saqueton R, Batteson TJ.

MedEdPORTAL. 2019 Apr 18;15:10818. doi: 10.15766/mep_2374-8265.10818.

5.

Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8+ T-Cell Activation.

Wang Z, Vaughan TY, Zhu W, Chen Y, Fu G, Medrzycki M, Nishio H, Bunting ST, Hankey-Giblin PA, Nusrat A, Parkos CA, Wang D, Wen R, Bunting KD.

Front Immunol. 2019 Mar 18;10:486. doi: 10.3389/fimmu.2019.00486. eCollection 2019.

6.

PALB2 connects BRCA1 and BRCA2 in the G2/M checkpoint response.

Simhadri S, Vincelli G, Huo Y, Misenko S, Foo TK, Ahlskog J, Sørensen CS, Oakley GG, Ganesan S, Bunting SF, Xia B.

Oncogene. 2019 Mar;38(10):1585-1596. doi: 10.1038/s41388-018-0535-2. Epub 2018 Oct 18.

7.

Antiparallel Coiled-Coil Interactions Mediate the Homodimerization of the DNA Damage-Repair Protein PALB2.

Song F, Li M, Liu G, Swapna GVT, Daigham NS, Xia B, Montelione GT, Bunting SF.

Biochemistry. 2018 Nov 27;57(47):6581-6591. doi: 10.1021/acs.biochem.8b00789. Epub 2018 Nov 8.

PMID:
30289697
8.

VX-984 is a selective inhibitor of non-homologous end joining, with possible preferential activity in transformed cells.

Khan AJ, Misenko SM, Thandoni A, Schiff D, Jhawar SR, Bunting SF, Haffty BG.

Oncotarget. 2018 May 25;9(40):25833-25841. doi: 10.18632/oncotarget.25383. eCollection 2018 May 25.

9.

Congenital dyserythropoietic anaemia type I diagnosed in a young adult with a history of splenectomy in childhood for presumed haemolytic anaemia.

Chonat S, McLemore ML, Bunting ST, Nortman S, Zhang K, Kalfa TA.

Br J Haematol. 2018 Jul;182(1):10. doi: 10.1111/bjh.15217. Epub 2018 Apr 20. No abstract available.

PMID:
29676459
10.

DNA repair and cell cycle checkpoint defects in a mouse model of 'BRCAness' are partially rescued by 53BP1 deletion.

Misenko SM, Patel DS, Her J, Bunting SF.

Cell Cycle. 2018;17(7):881-891. doi: 10.1080/15384101.2018.1456295. Epub 2018 May 15.

11.

How cells ensure correct repair of DNA double-strand breaks.

Her J, Bunting SF.

J Biol Chem. 2018 Jul 6;293(27):10502-10511. doi: 10.1074/jbc.TM118.000371. Epub 2018 Feb 5. Review.

12.

53BP1 Mediates ATR-Chk1 Signaling and Protects Replication Forks under Conditions of Replication Stress.

Her J, Ray C, Altshuler J, Zheng H, Bunting SF.

Mol Cell Biol. 2018 Mar 29;38(8). pii: e00472-17. doi: 10.1128/MCB.00472-17. Print 2018 Apr 15.

13.

Gene Therapy with BMN 270 Results in Therapeutic Levels of FVIII in Mice and Primates and Normalization of Bleeding in Hemophilic Mice.

Bunting S, Zhang L, Xie L, Bullens S, Mahimkar R, Fong S, Sandza K, Harmon D, Yates B, Handyside B, Sihn CR, Galicia N, Tsuruda L, O'Neill CA, Bagri A, Colosi P, Long S, Vehar G, Carter B.

Mol Ther. 2018 Feb 7;26(2):496-509. doi: 10.1016/j.ymthe.2017.12.009. Epub 2017 Dec 14.

14.

The BLM Helicase: Keeping recombination honest?

Her J, Ray C, Bunting SF.

Cell Cycle. 2018;17(4):401-402. doi: 10.1080/15384101.2017.1421045. Epub 2018 Jan 16. No abstract available.

15.

Utility and correlation of known anticoagulation parameters in the management of pediatric ventricular assist devices.

Bhatia AK, Yabrodi M, Carroll M, Bunting S, Kanter K, Maher KO, Deshpande SR.

World J Cardiol. 2017 Sep 26;9(9):749-756. doi: 10.4330/wjc.v9.i9.749.

16.

Utility of Fluorescence In Situ Hybridization Panel for Myelodysplastic Syndrome in Evaluation of Cytopenia in a Pediatric Hospital: A 5-Year Retrospective Review and Utilization Management.

Bunting CT, Senior T, Susson Y, Rivera A, Saxe D, Bunting ST.

Lab Med. 2017 Aug 1;48(3):266-270. doi: 10.1093/labmed/lmx047.

PMID:
28934515
17.

BLM helicase regulates DNA repair by counteracting RAD51 loading at DNA double-strand break sites.

Patel DS, Misenko SM, Her J, Bunting SF.

J Cell Biol. 2017 Nov 6;216(11):3521-3534. doi: 10.1083/jcb.201703144. Epub 2017 Sep 14.

18.

Clearance of Heparan Sulfate and Attenuation of CNS Pathology by Intracerebroventricular BMN 250 in Sanfilippo Type B Mice.

Aoyagi-Scharber M, Crippen-Harmon D, Lawrence R, Vincelette J, Yogalingam G, Prill H, Yip BK, Baridon B, Vitelli C, Lee A, Gorostiza O, Adintori EG, Minto WC, Van Vleet JL, Yates B, Rigney S, Christianson TM, Tiger PMN, Lo MJ, Holtzinger J, Fitzpatrick PA, LeBowitz JH, Bullens S, Crawford BE, Bunting S.

Mol Ther Methods Clin Dev. 2017 Jun 6;6:43-53. doi: 10.1016/j.omtm.2017.05.009. eCollection 2017 Sep 15.

19.

A Lysine Desert Protects a Novel Domain in the Slx5-Slx8 SUMO Targeted Ub Ligase To Maintain Sumoylation Levels in Saccharomyces cerevisiae.

Sharma P, Mullen JR, Li M, Zaratiegui M, Bunting SF, Brill SJ.

Genetics. 2017 Aug;206(4):1807-1821. doi: 10.1534/genetics.117.202697. Epub 2017 May 26.

20.

An Unfortunate Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Change (POEMS).

Afridi F, Otoya J, Bunting SF, Chaaya G.

Cureus. 2017 Mar 8;9(3):e1086. doi: 10.7759/cureus.1086.

21.

Can greening of aquaculture sequester blue carbon?

Ahmed N, Bunting SW, Glaser M, Flaherty MS, Diana JS.

Ambio. 2017 May;46(4):468-477. doi: 10.1007/s13280-016-0849-7. Epub 2016 Nov 15.

22.

Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment.

Dong L, Yu WM, Zheng H, Loh ML, Bunting ST, Pauly M, Huang G, Zhou M, Broxmeyer HE, Scadden DT, Qu CK.

Nature. 2016 Nov 10;539(7628):304-308. doi: 10.1038/nature20131. Epub 2016 Oct 26.

23.

53BP1 ablation rescues genomic instability in mice expressing 'RING-less' BRCA1.

Li M, Cole F, Patel DS, Misenko SM, Her J, Malhowski A, Alhamza A, Zheng H, Baer R, Ludwig T, Jasin M, Nussenzweig A, Serrano L, Bunting SF.

EMBO Rep. 2016 Nov;17(11):1532-1541. Epub 2016 Sep 26.

24.

Single-platelet nanomechanics measured by high-throughput cytometry.

Myers DR, Qiu Y, Fay ME, Tennenbaum M, Chester D, Cuadrado J, Sakurai Y, Baek J, Tran R, Ciciliano JC, Ahn B, Mannino RG, Bunting ST, Bennett C, Briones M, Fernandez-Nieves A, Smith ML, Brown AC, Sulchek T, Lam WA.

Nat Mater. 2017 Feb;16(2):230-235. doi: 10.1038/nmat4772. Epub 2016 Oct 10.

25.

A variant c-KIT mutation, D816H, fundamental to the sequential development of an ovarian mixed germ cell tumor and systemic mastocytosis with chronic myelomonocytic leukemia.

Mitchell SG, Bunting ST, Saxe D, Olson T, Keller FG.

Pediatr Blood Cancer. 2017 Apr;64(4). doi: 10.1002/pbc.26282. Epub 2016 Oct 26.

PMID:
27781377
26.

SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage.

Hong X, Liu W, Song R, Shah JJ, Feng X, Tsang CK, Morgan KM, Bunting SF, Inuzuka H, Zheng XF, Shen Z, Sabaawy HE, Liu L, Pine SR.

Nucleic Acids Res. 2016 Oct 14;44(18):8855-8869. Epub 2016 Aug 26.

27.

SIRT7 promotes genome integrity and modulates non-homologous end joining DNA repair.

Vazquez BN, Thackray JK, Simonet NG, Kane-Goldsmith N, Martinez-Redondo P, Nguyen T, Bunting S, Vaquero A, Tischfield JA, Serrano L.

EMBO J. 2016 Jul 15;35(14):1488-503. doi: 10.15252/embj.201593499. Epub 2016 May 24.

28.

Early T-Cell Precursor Acute Lymphoblastic Leukemia in an Infant With an NRAS Q61R Mutation and Clinical Features of Juvenile Myelomonocytic Leukemia.

Raikar SS, Scarborough JD, Sabnis H, Bergsagel J, Wu D, Cooper TM, Keller FG, Wood BL, Bunting ST.

Pediatr Blood Cancer. 2016 Sep;63(9):1667-70. doi: 10.1002/pbc.26050. Epub 2016 May 4.

PMID:
27145535
29.

Hematogones With Lambda Light Chain Restriction in a 4-Year-Old Boy With Burkitt Lymphoma: A Potential Diagnostic Pitfall.

Guillory T, Li S, Bergsagel DJ, Weinzierl E, Bunting ST.

Lab Med. 2016 May;47(2):163-70. doi: 10.1093/labmed/lmw009.

30.

Stat5-deficient hematopoiesis is permissive for Myc-induced B-cell leukemogenesis.

Wang Z, Medrzycki M, Bunting ST, Bunting KD.

Oncotarget. 2015 Oct 6;6(30):28961-72. doi: 10.18632/oncotarget.5009.

31.

Therapeutic Hypothermia in Deceased Organ Donors and Kidney-Graft Function.

Niemann CU, Feiner J, Swain S, Bunting S, Friedman M, Crutchfield M, Broglio K, Hirose R, Roberts JP, Malinoski D.

N Engl J Med. 2015 Jul 30;373(5):405-14. doi: 10.1056/NEJMoa1501969.

32.

Long-term monitoring of western aspen--lessons learned.

Strand EK, Bunting SC, Starcevich LA, Nahorniak MT, Dicus G, Garrett LK.

Environ Monit Assess. 2015 Aug;187(8):528. doi: 10.1007/s10661-015-4746-5. Epub 2015 Jul 28.

PMID:
26215826
33.

AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis.

Park J, Schlederer M, Schreiber M, Ice R, Merkel O, Bilban M, Hofbauer S, Kim S, Addison J, Zou J, Ji C, Bunting ST, Wang Z, Shoham M, Huang G, Bago-Horvath Z, Gibson LF, Rojanasakul Y, Remick S, Ivanov A, Pugacheva E, Bunting KD, Moriggl R, Kenner L, Tse W.

Oncotarget. 2015 Aug 21;6(24):20697-710.

34.

Neutral endopeptidase-resistant C-type natriuretic peptide variant represents a new therapeutic approach for treatment of fibroblast growth factor receptor 3-related dwarfism.

Wendt DJ, Dvorak-Ewell M, Bullens S, Lorget F, Bell SM, Peng J, Castillo S, Aoyagi-Scharber M, O'Neill CA, Krejci P, Wilcox WR, Rimoin DL, Bunting S.

J Pharmacol Exp Ther. 2015 Apr;353(1):132-49. doi: 10.1124/jpet.114.218560. Epub 2015 Feb 3.

PMID:
25650377
35.

Delivery of an enzyme-IGFII fusion protein to the mouse brain is therapeutic for mucopolysaccharidosis type IIIB.

Kan SH, Aoyagi-Scharber M, Le SQ, Vincelette J, Ohmi K, Bullens S, Wendt DJ, Christianson TM, Tiger PM, Brown JR, Lawrence R, Yip BK, Holtzinger J, Bagri A, Crippen-Harmon D, Vondrak KN, Chen Z, Hague CM, Woloszynek JC, Cheung DS, Webster KA, Adintori EG, Lo MJ, Wong W, Fitzpatrick PA, LeBowitz JH, Crawford BE, Bunting S, Dickson PI, Neufeld EF.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14870-5. doi: 10.1073/pnas.1416660111. Epub 2014 Sep 29.

36.

Concomitant a novel ALAS2 mutation and GATA1 mutation in a newborn: a case report and review of the literature.

Doshi BS, Abramowsky C, Briones M, Bunting ST.

Am J Blood Res. 2014 Sep 5;4(1):41-5. eCollection 2014.

37.

Rapid analysis of chromosome aberrations in mouse B lymphocytes by PNA-FISH.

Misenko SM, Bunting SF.

J Vis Exp. 2014 Aug 19;(90). doi: 10.3791/51806.

38.

Disposable platform provides visual and color-based point-of-care anemia self-testing.

Tyburski EA, Gillespie SE, Stoy WA, Mannino RG, Weiss AJ, Siu AF, Bulloch RH, Thota K, Cardenas A, Session W, Khoury HJ, O'Connor S, Bunting ST, Boudreaux J, Forest CR, Gaddh M, Leong T, Lyon LA, Lam WA.

J Clin Invest. 2014 Oct;124(10):4387-94. doi: 10.1172/JCI76666. Epub 2014 Aug 26.

39.

Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice.

Simhadri S, Peterson S, Patel DS, Huo Y, Cai H, Bowman-Colin C, Miller S, Ludwig T, Ganesan S, Bhaumik M, Bunting SF, Jasin M, Xia B.

J Biol Chem. 2014 Aug 29;289(35):24617-29. doi: 10.1074/jbc.M114.566141. Epub 2014 Jul 11.

40.

Capillary nano-immunoassay for Akt 1/2/3 and 4EBP1 phosphorylation in acute myeloid leukemia.

Sabnis H, Bradley HL, Bunting ST, Cooper TM, Bunting KD.

J Transl Med. 2014 Jun 12;12:166. doi: 10.1186/1479-5876-12-166.

41.

“Russell-like” bodies in Philadelphia chromosome–positive B-lymphoblastic leukemia.

Bunting ST, Lew G.

Blood. 2014 Apr 17;123(16):2448. doi: 10.1182/blood-2014-01-547513. No abstract available.

42.

CtIP-mediated resection is essential for viability and can operate independently of BRCA1.

Polato F, Callen E, Wong N, Faryabi R, Bunting S, Chen HT, Kozak M, Kruhlak MJ, Reczek CR, Lee WH, Ludwig T, Baer R, Feigenbaum L, Jackson S, Nussenzweig A.

J Exp Med. 2014 Jun 2;211(6):1027-36. doi: 10.1084/jem.20131939. Epub 2014 May 19.

43.

Arginine 199 and leucine 208 have key roles in the control of adenosine A2A receptor signalling function.

Bertheleme N, Strege A, Bunting SE, Dowell SJ, Byrne B.

PLoS One. 2014 Mar 3;9(3):e89613. doi: 10.1371/journal.pone.0089613. eCollection 2014.

44.

An object-based image analysis of pinyon and juniper woodlands treated to reduce fuels.

Hulet A, Roundy BA, Petersen SL, Jensen RR, Bunting SC.

Environ Manage. 2014 Mar;53(3):660-71. doi: 10.1007/s00267-013-0227-1. Epub 2014 Jan 9.

PMID:
24402578
45.

Lymphomas and lymphoproliferative disorders clinically presenting as renal carcinoma: a clinicopathological study of 14 cases.

Chen L, Richendollar B, Bunting S, Campbell S, Zhou M.

Pathology. 2013 Dec;45(7):657-63. doi: 10.1097/PAT.0000000000000006.

PMID:
24247623
46.

Specific inhibition of ectodomain shedding of glycoprotein Ibα by targeting its juxtamembrane shedding cleavage site.

Liang X, Russell SR, Estelle S, Jones LH, Cho S, Kahn ML, Berndt MC, Bunting ST, Ware J, Li R.

J Thromb Haemost. 2013 Dec;11(12):2155-62. doi: 10.1111/jth.12425.

47.

Targeting oxidized LDL improves insulin sensitivity and immune cell function in obese Rhesus macaques.

Li S, Kievit P, Robertson AK, Kolumam G, Li X, von Wachenfeldt K, Valfridsson C, Bullens S, Messaoudi I, Bader L, Cowan KJ, Kamath A, van Bruggen N, Bunting S, Frendéus B, Grove KL.

Mol Metab. 2013 Jun 11;2(3):256-69. doi: 10.1016/j.molmet.2013.06.001. eCollection 2013.

48.

Engineered neural tissue for peripheral nerve repair.

Georgiou M, Bunting SC, Davies HA, Loughlin AJ, Golding JP, Phillips JB.

Biomaterials. 2013 Oct;34(30):7335-43. doi: 10.1016/j.biomaterials.2013.06.025. Epub 2013 Jul 5.

49.

Alloantibodies to a paternally derived RBC KEL antigen lead to hemolytic disease of the fetus/newborn in a murine model.

Stowell SR, Henry KL, Smith NH, Hudson KE, Halverson GR, Park JC, Bennett AM, Girard-Pierce KR, Arthur CM, Bunting ST, Zimring JC, Hendrickson JE.

Blood. 2013 Aug 22;122(8):1494-504. doi: 10.1182/blood-2013-03-488874. Epub 2013 Jun 25.

50.

End-joining, translocations and cancer.

Bunting SF, Nussenzweig A.

Nat Rev Cancer. 2013 Jul;13(7):443-54. doi: 10.1038/nrc3537. Epub 2013 Jun 13. Review.

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