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Gold and silver dichroic nanocomposite in the quest for 3D printing the Lycurgus cup.

Kool L, Dekker F, Bunschoten A, Smales GJ, Pauw BR, Velders AH, Saggiomo V.

Beilstein J Nanotechnol. 2020 Jan 2;11:16-23. doi: 10.3762/bjnano.11.2. eCollection 2020.


COvalent monolayer patterns in Microfluidics by PLasma etching Open Technology - COMPLOT.

Willems SBJ, Zegers J, Bunschoten A, Wagterveld RM, van Leeuwen FWB, Velders AH, Saggiomo V.

Analyst. 2020 Mar 2;145(5):1629-1635. doi: 10.1039/c9an02407g.


On-Flow Immobilization of Polystyrene Microspheres on β-Cyclodextrin-Patterned Silica Surfaces through Supramolecular Host-Guest Interactions.

Willems SBJ, Bunschoten A, Wagterveld RM, van Leeuwen FWB, Velders AH.

ACS Appl Mater Interfaces. 2019 Oct 2;11(39):36221-36231. doi: 10.1021/acsami.9b11069. Epub 2019 Sep 18.


In ovaries with high or low variation in follicle size, granulosa cells of antral follicles exhibit distinct size-related processes.

Costermans NGJ, Keijer J, van Schothorst EM, Kemp B, Keshtkar S, Bunschoten A, Soede NM, Teerds KJ.

Mol Hum Reprod. 2019 Oct 28;25(10):614-624. doi: 10.1093/molehr/gaz042.


A tracer-based method enables tracking of Plasmodium falciparum malaria parasites during human skin infection.

Winkel BMF, de Korne CM, van Oosterom MN, Staphorst D, Bunschoten A, Langenberg MCC, Chevalley-Maurel SC, Janse CJ, Franke-Fayard B, van Leeuwen FWB, Roestenberg M.

Theranostics. 2019 Apr 13;9(10):2768-2778. doi: 10.7150/thno.33467. eCollection 2019.


Covalently bound monolayer patterns obtained by plasma etching on glass surfaces.

Willems SBJ, Schijven LMI, Bunschoten A, van Leeuwen FWB, Velders AH, Saggiomo V.

Chem Commun (Camb). 2019 Jul 7;55(53):7667-7670. doi: 10.1039/c9cc03791h. Epub 2019 Jun 17.


Multimodal Tracking of Controlled Staphylococcus aureus Infections in Mice.

Welling MM, de Korne CM, Spa SJ, van Willigen DM, Hensbergen AW, Bunschoten A, Duszenko N, Smits WK, Roestenberg M, van Leeuwen FWB.

ACS Infect Dis. 2019 Jul 12;5(7):1160-1168. doi: 10.1021/acsinfecdis.9b00015. Epub 2019 May 2.


Gold nanoparticles embedded in a polymer as a 3D-printable dichroic nanocomposite material.

Kool L, Bunschoten A, Velders AH, Saggiomo V.

Beilstein J Nanotechnol. 2019 Feb 12;10:442-447. doi: 10.3762/bjnano.10.43. eCollection 2019.


Cyclodextrin-based complex coacervate core micelles with tuneable supramolecular host-guest, metal-to-ligand and charge interactions.

Facciotti C, Saggiomo V, Bunschoten A, Fokkink R, Hove JBT, Wang J, Velders AH.

Soft Matter. 2018 Dec 5;14(47):9542-9549. doi: 10.1039/c8sm01504j.


Presence of anti-Müllerian hormone (AMH) during follicular development in the porcine ovary.

Almeida FRCL, Costermans NGJ, Soede NM, Bunschoten A, Keijer J, Kemp B, Teerds KJ.

PLoS One. 2018 Jul 31;13(7):e0197894. doi: 10.1371/journal.pone.0197894. eCollection 2018.


Sortase A-mediated site-specific labeling of camelid single-domain antibody-fragments: a versatile strategy for multiple molecular imaging modalities.

Massa S, Vikani N, Betti C, Ballet S, Vanderhaegen S, Steyaert J, Descamps B, Vanhove C, Bunschoten A, van Leeuwen FW, Hernot S, Caveliers V, Lahoutte T, Muyldermans S, Xavier C, Devoogdt N.

Contrast Media Mol Imaging. 2016 Sep;11(5):328-339. doi: 10.1002/cmmi.1696. Epub 2016 May 5.


Evaluation of a Fluorescent and Radiolabeled Hybrid Somatostatin Analog In Vitro and in Mice Bearing H69 Neuroendocrine Xenografts.

Santini C, Kuil J, Bunschoten A, Pool S, de Blois E, Ridwan Y, Essers J, Bernsen MR, van Leeuwen FW, de Jong M.

J Nucl Med. 2016 Aug;57(8):1289-95. doi: 10.2967/jnumed.115.164970. Epub 2016 Apr 28.


Tailoring Fluorescent Dyes To Optimize a Hybrid RGD-Tracer.

Bunschoten A, van Willigen DM, Buckle T, van den Berg NS, Welling MM, Spa SJ, Wester HJ, van Leeuwen FW.

Bioconjug Chem. 2016 May 18;27(5):1253-8. doi: 10.1021/acs.bioconjchem.6b00093. Epub 2016 Apr 28.


Fluorescence guided surgery and tracer-dose, fact or fiction?

KleinJan GH, Bunschoten A, van den Berg NS, Olmos RA, Klop WM, Horenblas S, van der Poel HG, Wester HJ, van Leeuwen FW.

Eur J Nucl Med Mol Imaging. 2016 Sep;43(10):1857-67. doi: 10.1007/s00259-016-3372-y. Epub 2016 Mar 28.


Dietary-Induced Chronic Hypothyroidism Negatively Affects Rat Follicular Development and Ovulation Rate and Is Associated with Oxidative Stress.

Meng L, Rijntjes E, Swarts H, Bunschoten A, van der Stelt I, Keijer J, Teerds K.

Biol Reprod. 2016 Apr;94(4):90. doi: 10.1095/biolreprod.115.136515. Epub 2016 Mar 9.


Improved muscle function and quality after diet intervention with leucine-enriched whey and antioxidants in antioxidant deficient aged mice.

van Dijk M, Dijk FJ, Bunschoten A, van Dartel DA, van Norren K, Walrand S, Jourdan M, Verlaan S, Luiking Y.

Oncotarget. 2016 Apr 5;7(14):17338-55. doi: 10.18632/oncotarget.7800.


Erratum to: First-in-human evaluation of a hybrid modality that allows combined radio- and (near-infrared) fluorescence tracing during surgery.

van den Berg NS, Simon H, Kleinjan GH, Engelen T, Bunschoten A, Welling MM, Tijink BM, Horenblas S, Chambron J, van Leeuwen FWB.

Eur J Nucl Med Mol Imaging. 2015 Oct;42(11):1780. doi: 10.1007/s00259-015-3133-3. No abstract available.


First-in-human evaluation of a hybrid modality that allows combined radio- and (near-infrared) fluorescence tracing during surgery.

van den Berg NS, Simon H, Kleinjan GH, Engelen T, Bunschoten A, Welling MM, Tijink BM, Horenblas S, Chambron J, van Leeuwen FWB.

Eur J Nucl Med Mol Imaging. 2015 Oct;42(11):1639-1647. doi: 10.1007/s00259-015-3109-3. Epub 2015 Jun 25. Erratum in: Eur J Nucl Med Mol Imaging. 2015 Oct;42(11):1780.


Development of a Hybrid Tracer for SPECT and Optical Imaging of Bacterial Infections.

Welling MM, Bunschoten A, Kuil J, Nelissen RG, Beekman FJ, Buckle T, van Leeuwen FW.

Bioconjug Chem. 2015 May 20;26(5):839-49. doi: 10.1021/acs.bioconjchem.5b00062. Epub 2015 Apr 20.


Enhanced glutathione PEGylated liposomal brain delivery of an anti-amyloid single domain antibody fragment in a mouse model for Alzheimer's disease.

Rotman M, Welling MM, Bunschoten A, de Backer ME, Rip J, Nabuurs RJ, Gaillard PJ, van Buchem MA, van der Maarel SM, van der Weerd L.

J Control Release. 2015 Apr 10;203:40-50. doi: 10.1016/j.jconrel.2015.02.012. Epub 2015 Feb 7.


U-SPECT-BioFluo: an integrated radionuclide, bioluminescence, and fluorescence imaging platform.

van Oosterom MN, Kreuger R, Buckle T, Mahn WA, Bunschoten A, Josephson L, van Leeuwen FW, Beekman FJ.

EJNMMI Res. 2014 Oct 11;4:56. doi: 10.1186/s13550-014-0056-0. eCollection 2014.


Dynamic changes in energy metabolism upon embryonic stem cell differentiation support developmental toxicant identification.

van Dartel DA, Schulpen SH, Theunissen PT, Bunschoten A, Piersma AH, Keijer J.

Toxicology. 2014 Oct 3;324:76-87. doi: 10.1016/j.tox.2014.07.009. Epub 2014 Jul 30.


Role of Frizzled6 in the molecular mechanism of beta-carotene action in the lung.

Piga R, van Dartel D, Bunschoten A, van der Stelt I, Keijer J.

Toxicology. 2014 Jun 5;320:67-73. doi: 10.1016/j.tox.2014.03.002. Epub 2014 Mar 21.


Identification of early transcriptome-based biomarkers related to lipid metabolism in peripheral blood mononuclear cells of rats nutritionally programmed for improved metabolic health.

Konieczna J, Sánchez J, van Schothorst EM, Torrens JM, Bunschoten A, Palou M, Picó C, Keijer J, Palou A.

Genes Nutr. 2014 Jan;9(1):366. doi: 10.1007/s12263-013-0366-2. Epub 2013 Dec 17.


Thermoneutrality results in prominent diet-induced body weight differences in C57BL/6J mice, not paralleled by diet-induced metabolic differences.

Hoevenaars FP, Bekkenkamp-Grovenstein M, Janssen RJ, Heil SG, Bunschoten A, Hoek-van den Hil EF, Snaas-Alders S, Teerds K, van Schothorst EM, Keijer J.

Mol Nutr Food Res. 2014 Apr;58(4):799-807. doi: 10.1002/mnfr.201300285. Epub 2013 Nov 18.


Development and prospects of dedicated tracers for the molecular imaging of bacterial infections.

Bunschoten A, Welling MM, Termaat MF, Sathekge M, van Leeuwen FW.

Bioconjug Chem. 2013 Dec 18;24(12):1971-89. doi: 10.1021/bc4003037. Epub 2013 Nov 20. Review.


Effects of chocolate supplementation on metabolic and cardiovascular parameters in ApoE3L mice fed a high-cholesterol atherogenic diet.

Yakala GK, Wielinga PY, Suarez M, Bunschoten A, van Golde JM, Arola L, Keijer J, Kleemann R, Kooistra T, Heeringa P.

Mol Nutr Food Res. 2013 Nov;57(11):2039-48. doi: 10.1002/mnfr.201200858. Epub 2013 Aug 15.


Quercetin induces hepatic lipid omega-oxidation and lowers serum lipid levels in mice.

Hoek-van den Hil EF, Keijer J, Bunschoten A, Vervoort JJ, Stankova B, Bekkenkamp M, Herreman L, Venema D, Hollman PC, Tvrzicka E, Rietjens IM, van Schothorst EM.

PLoS One. 2013;8(1):e51588. doi: 10.1371/journal.pone.0051588. Epub 2013 Jan 24. Erratum in: PLoS One. 2013;8(9). doi:.1371/annotation/53e96376-38fe-40e7-b73a-60e7232cef0e.


Use of a single hybrid imaging agent for integration of target validation with in vivo and ex vivo imaging of mouse tumor lesions resembling human DCIS.

Buckle T, Kuil J, van den Berg NS, Bunschoten A, Lamb HJ, Yuan H, Josephson L, Jonkers J, Borowsky AD, van Leeuwen FW.

PLoS One. 2013;8(1):e48324. doi: 10.1371/journal.pone.0048324. Epub 2013 Jan 11.


Non-invasive longitudinal imaging of tumor progression using an (111)indium labeled CXCR4 peptide antagonist.

Buckle T, van Berg NS, Kuil J, Bunschoten A, Oldenburg J, Borowsky AD, Wesseling J, Masada R, Oishi S, Fujii N, van Leeuwen FW.

Am J Nucl Med Mol Imaging. 2012;2(1):99-109. Epub 2011 Dec 15.


Preservation of metabolic flexibility in skeletal muscle by a combined use of n-3 PUFA and rosiglitazone in dietary obese mice.

Horakova O, Medrikova D, van Schothorst EM, Bunschoten A, Flachs P, Kus V, Kuda O, Bardova K, Janovska P, Hensler M, Rossmeisl M, Wang-Sattler R, Prehn C, Adamski J, Illig T, Keijer J, Kopecky J.

PLoS One. 2012;7(8):e43764. doi: 10.1371/journal.pone.0043764. Epub 2012 Aug 31.


Imprinted polymers displaying high affinity for sulfated protein fragments.

Shinde S, Bunschoten A, Kruijtzer JA, Liskamp RM, Sellergren B.

Angew Chem Int Ed Engl. 2012 Aug 13;51(33):8326-9. doi: 10.1002/anie.201201314. Epub 2012 Jul 5. No abstract available.


Image navigation as a means to expand the boundaries of fluorescence-guided surgery.

Brouwer OR, Buckle T, Bunschoten A, Kuil J, Vahrmeijer AL, Wendler T, Valdés-Olmos RA, van der Poel HG, van Leeuwen FW.

Phys Med Biol. 2012 May 21;57(10):3123-36. doi: 10.1088/0031-9155/57/10/3123. Epub 2012 May 1.


Multimodal interventional molecular imaging of tumor margins and distant metastases by targeting αvβ3 integrin.

Bunschoten A, Buckle T, Visser NL, Kuil J, Yuan H, Josephson L, Vahrmeijer AL, van Leeuwen FW.

Chembiochem. 2012 May 7;13(7):1039-45. doi: 10.1002/cbic.201200034. Epub 2012 Apr 13.


Targeted non-covalent self-assembled nanoparticles based on human serum albumin.

Bunschoten A, Buckle T, Kuil J, Luker GD, Luker KE, Nieweg OE, van Leeuwen FW.

Biomaterials. 2012 Jan;33(3):867-75. doi: 10.1016/j.biomaterials.2011.10.005. Epub 2011 Oct 22.


Dietary restriction of mice on a high-fat diet induces substrate efficiency and improves metabolic health.

Duivenvoorde LP, van Schothorst EM, Bunschoten A, Keijer J.

J Mol Endocrinol. 2011 Aug;47(1):81-97.


Glycemic index differences of high-fat diets modulate primarily lipid metabolism in murine adipose tissue.

van Schothorst EM, Bunschoten A, Verlinde E, Schrauwen P, Keijer J.

Physiol Genomics. 2011 Aug 16;43(15):942-9. doi: 10.1152/physiolgenomics.00042.2011. Epub 2011 Jun 14.


Dietary restriction of mice on a high-fat diet induces substrate efficiency and improves metabolic health.

Duivenvoorde LP, van Schothorst EM, Bunschoten A, Keijer J.

J Mol Endocrinol. 2011 Aug 3;47(1):81-97. Print 2011.


A peptide mimic of the chemotaxis inhibitory protein of Staphylococcus aureus: towards the development of novel anti-inflammatory compounds.

Bunschoten A, Ippel JH, Kruijtzer JA, Feitsma L, de Haas CJ, Liskamp RM, Kemmink J.

Amino Acids. 2011 Feb;40(2):731-40. doi: 10.1007/s00726-010-0711-3. Epub 2010 Aug 4.


An 8-week high-fat diet induces obesity and insulin resistance with small changes in the muscle transcriptome of C57BL/6J mice.

de Wilde J, Smit E, Mohren R, Boekschoten MV, de Groot P, van den Berg SA, Bijland S, Voshol PJ, van Dijk KW, de Wit NW, Bunschoten A, Schaart G, Hulshof MF, Mariman EC.

J Nutrigenet Nutrigenomics. 2009;2(6):280-91. doi: 10.1159/000308466. Epub 2010 Jun 28.


Downregulation of Fzd6 and Cthrc1 and upregulation of olfactory receptors and protocadherins by dietary beta-carotene in lungs of Bcmo1-/- mice.

van Helden YG, Godschalk RW, Heil SG, Bunschoten A, Hessel S, Amengual J, Bonet ML, von Lintig J, van Schooten FJ, Keijer J.

Carcinogenesis. 2010 Aug;31(8):1329-37. doi: 10.1093/carcin/bgq083. Epub 2010 May 14.


CHIPS binds to the phosphorylated N-terminus of the C5a-receptor.

Bunschoten A, Feitsma LJ, Kruijtzer JA, de Haas CJ, Liskamp RM, Kemmink J.

Bioorg Med Chem Lett. 2010 Jun 1;20(11):3338-40. doi: 10.1016/j.bmcl.2010.04.028. Epub 2010 Apr 14.


Transcriptome analysis in benefit-risk assessment of micronutrients and bioactive food components.

Keijer J, van Helden YG, Bunschoten A, van Schothorst EM.

Mol Nutr Food Res. 2010 Feb;54(2):240-8. doi: 10.1002/mnfr.200900304. Review.


A general sequence independent solid phase method for the site specific synthesis of multiple sulfated-tyrosine containing peptides.

Bunschoten A, Kruijtzer JA, Ippel JH, de Haas CJ, van Strijp JA, Kemmink J, Liskamp RM.

Chem Commun (Camb). 2009 Jun 7;(21):2999-3001. doi: 10.1039/b823425f. Epub 2009 Mar 9.


Induction of lipid oxidation by polyunsaturated fatty acids of marine origin in small intestine of mice fed a high-fat diet.

van Schothorst EM, Flachs P, Franssen-van Hal NL, Kuda O, Bunschoten A, Molthoff J, Vink C, Hooiveld GJ, Kopecky J, Keijer J.

BMC Genomics. 2009 Mar 16;10:110. doi: 10.1186/1471-2164-10-110.


Structure of the tyrosine-sulfated C5a receptor N terminus in complex with chemotaxis inhibitory protein of Staphylococcus aureus.

Ippel JH, de Haas CJ, Bunschoten A, van Strijp JA, Kruijtzer JA, Liskamp RM, Kemmink J.

J Biol Chem. 2009 May 1;284(18):12363-72. doi: 10.1074/jbc.M808179200. Epub 2009 Feb 27.


Effects of a high-fat, low- versus high-glycemic index diet: retardation of insulin resistance involves adipose tissue modulation.

van Schothorst EM, Bunschoten A, Schrauwen P, Mensink RP, Keijer J.

FASEB J. 2009 Apr;23(4):1092-101. doi: 10.1096/fj.08-117119. Epub 2008 Nov 24.


Synthesis and evaluation of chloromethyl sulfoxides as a new class of selective irreversible cysteine protease inhibitors.

Brouwer AJ, Bunschoten A, Liskamp RM.

Bioorg Med Chem. 2007 Nov 15;15(22):6985-93. Epub 2007 Aug 22.


Absence of an adipogenic effect of rosiglitazone on mature 3T3-L1 adipocytes: increase of lipid catabolism and reduction of adipokine expression.

Wang P, Renes J, Bouwman F, Bunschoten A, Mariman E, Keijer J.

Diabetologia. 2007 Mar;50(3):654-65. Epub 2007 Jan 24.


Insulin modulates the secretion of proteins from mature 3T3-L1 adipocytes: a role for transcriptional regulation of processing.

Wang P, Keijer J, Bunschoten A, Bouwman F, Renes J, Mariman E.

Diabetologia. 2006 Oct;49(10):2453-62. Epub 2006 Aug 4.


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