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Items: 1 to 50 of 214

1.

Treating sickle cell disease by targeting HbS polymerization.

Eaton WA, Bunn HF.

Blood. 2017 May 18;129(20):2719-2726. doi: 10.1182/blood-2017-02-765891. Epub 2017 Apr 6. Review.

2.

Red cell survival and NO scavenging in sickle cell disease.

Bunn HF.

Am J Hematol. 2016 Dec;91(12):1173-1174. doi: 10.1002/ajh.24576. No abstract available.

3.

Vitamin B12 and pernicious anemia--the dawn of molecular medicine.

Bunn HF.

N Engl J Med. 2014 Feb 20;370(8):773-6. doi: 10.1056/NEJMcibr1315544. No abstract available.

PMID:
24552327
4.

Erythropoietin.

Bunn HF.

Cold Spring Harb Perspect Med. 2013 Mar 1;3(3):a011619. doi: 10.1101/cshperspect.a011619. Review.

5.

Classification of the disorders of hemoglobin.

Forget BG, Bunn HF.

Cold Spring Harb Perspect Med. 2013 Feb 1;3(2):a011684. doi: 10.1101/cshperspect.a011684. Review.

6.

Practicing biochemistry without a license.

Bunn HF.

J Biol Chem. 2013 Feb 15;288(7):5062-71. doi: 10.1074/jbc.X113.451591. Epub 2013 Jan 8. No abstract available.

7.

The triumph of good over evil: protection by the sickle gene against malaria.

Bunn HF.

Blood. 2013 Jan 3;121(1):20-5. doi: 10.1182/blood-2012-08-449397. Epub 2012 Nov 1. Review.

PMID:
23118217
8.

Development of diabetes in lean Ncb5or-null mice is associated with manifestations of endoplasmic reticulum and oxidative stress in beta cells.

Wang W, Guo Y, Xu M, Huang HH, Novikova L, Larade K, Jiang ZG, Thayer TC, Frontera JR, Aires D, Ding H, Turk J, Mathews CE, Bunn HF, Stehno-Bittel L, Zhu H.

Biochim Biophys Acta. 2011 Nov;1812(11):1532-41. doi: 10.1016/j.bbadis.2011.07.016. Epub 2011 Aug 2.

9.

UROS and ALAS-2: erstwhile partners in crime.

Bunn HF.

Blood. 2011 Aug 11;118(6):1435-7. doi: 10.1182/blood-2011-06-361311. No abstract available.

PMID:
21835963
10.

Pulmonary hypertension and nitric oxide depletion in sickle cell disease.

Bunn HF, Nathan DG, Dover GJ, Hebbel RP, Platt OS, Rosse WF, Ware RE.

Blood. 2010 Aug 5;116(5):687-92. doi: 10.1182/blood-2010-02-268193. Epub 2010 Apr 15. Review.

PMID:
20395414
11.

End run around epo.

Bunn HF.

N Engl J Med. 2009 Nov 5;361(19):1901-3. doi: 10.1056/NEJMe0908186. No abstract available.

PMID:
19890135
12.

The flavoheme reductase Ncb5or protects cells against endoplasmic reticulum stress-induced lipotoxicity.

Zhang Y, Larade K, Jiang ZG, Ito S, Wang W, Zhu H, Bunn HF.

J Lipid Res. 2010 Jan;51(1):53-62. doi: 10.1194/jlr.M900146-JLR200.

13.

Loss of Ncb5or results in impaired fatty acid desaturation, lipoatrophy, and diabetes.

Larade K, Jiang Z, Zhang Y, Wang W, Bonner-Weir S, Zhu H, Bunn HF.

J Biol Chem. 2008 Oct 24;283(43):29285-91. doi: 10.1074/jbc.M804645200. Epub 2008 Aug 5.

14.

Pulmonary thrombectomy in a patient with hemoglobin Nottingham.

Memtsoudis SG, Lekowski RW Jr, Rosenberger P, Khalpey Z, FitzGerald DJ, Claypoole V, Courtney KD, Landzberg MJ, Bunn HF, Shekar PS.

Perfusion. 2007 Jul;22(4):299-301.

PMID:
18181520
15.

Hematopoietic cell transplantation for hemoglobinopathies.

Krishnamurti L, Bunn HF, Williams AM, Tolar J.

Curr Probl Pediatr Adolesc Health Care. 2008 Jan;38(1):6-18. Review. No abstract available.

PMID:
18068866
16.
17.

New agents that stimulate erythropoiesis.

Bunn HF.

Blood. 2007 Feb 1;109(3):868-73. Epub 2006 Oct 10. Review.

PMID:
17032916
18.
19.

Variation in NCB5OR: studies of relationships to type 2 diabetes, maturity-onset diabetes of the young, and gestational diabetes mellitus.

Andersen G, Wegner L, Rose CS, Xie J, Zhu H, Larade K, Johansen A, Ek J, Lauenborg J, Drivsholm T, Borch-Johnsen K, Damm P, Hansen T, Bunn HF, Pedersen O.

Diabetes. 2004 Nov;53(11):2992-7.

20.

Absence of a reductase, NCB5OR, causes insulin-deficient diabetes.

Xie J, Zhu H, Larade K, Ladoux A, Seguritan A, Chu M, Ito S, Bronson RT, Leiter EH, Zhang CY, Rosen ED, Bunn HF.

Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10750-5. Epub 2004 Jul 9.

21.
22.

Hypoxia-induced synthesis of hemoglobin in the crustacean Daphnia magna is hypoxia-inducible factor-dependent.

Gorr TA, Cahn JD, Yamagata H, Bunn HF.

J Biol Chem. 2004 Aug 20;279(34):36038-47. Epub 2004 May 28.

23.

NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum.

Zhu H, Larade K, Jackson TA, Xie J, Ladoux A, Acker H, Berchner-Pfannschmidt U, Fandrey J, Cross AR, Lukat-Rodgers GS, Rodgers KR, Bunn HF.

J Biol Chem. 2004 Jul 16;279(29):30316-25. Epub 2004 May 6.

24.

Hypoxia-inducible factor and its biomedical relevance.

Huang LE, Bunn HF.

J Biol Chem. 2003 May 30;278(22):19575-8. Epub 2003 Mar 14. Review. No abstract available.

25.

Sugar in erythropoietin: clinical and forensic implications.

Bunn HF.

Blood. 2002 Mar 1;99(5):1503. No abstract available.

PMID:
11861258
26.

Drug-induced autoimmune red-cell aplasia.

Bunn HF.

N Engl J Med. 2002 Feb 14;346(7):522-3. No abstract available.

PMID:
11844855
27.

Detecting and responding to hypoxia.

Zhu H, Jackson T, Bunn HF.

Nephrol Dial Transplant. 2002;17 Suppl 1:3-7. Review.

28.

Signal transduction. How do cells sense oxygen?

Zhu H, Bunn HF.

Science. 2001 Apr 20;292(5516):449-51. Epub 2001 Apr 5.

29.

Cadmium and platinum suppression of erythropoietin production in cell culture: clinical implications.

Horiguchi H, Kayama F, Oguma E, Willmore WG, Hradecky P, Bunn HF.

Blood. 2000 Dec 1;96(12):3743-7.

PMID:
11090055
30.

Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells.

Zhu H, Qiu H, Yoon HW, Huang S, Bunn HF.

Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14742-7.

31.

Regulation of the erythropoietin gene.

Ebert BL, Bunn HF.

Blood. 1999 Sep 15;94(6):1864-77. Review. No abstract available.

PMID:
10477715
32.
33.
34.

Induction of fetal hemoglobin in sickle cell disease.

Bunn HF.

Blood. 1999 Mar 15;93(6):1787-9. Review. No abstract available.

PMID:
10068648
35.
37.

Homodimerization restores biological activity to an inactive erythropoietin mutant.

Qiu H, Belanger A, Yoon HW, Bunn HF.

J Biol Chem. 1998 May 1;273(18):11173-6.

38.

Erythropoietin: a model system for studying oxygen-dependent gene regulation.

Bunn HF, Gu J, Huang LE, Park JW, Zhu H.

J Exp Biol. 1998 Apr;201(Pt 8):1197-201. Review.

39.

Pathogenesis and treatment of sickle cell disease.

Bunn HF.

N Engl J Med. 1997 Sep 11;337(11):762-9. Review. No abstract available.

PMID:
9287233
40.

Erythropoietin gene regulation depends on heme-dependent oxygen sensing and assembly of interacting transcription factors.

Huang LE, Ho V, Arany Z, Krainc D, Galson D, Tendler D, Livingston DM, Bunn HF.

Kidney Int. 1997 Feb;51(2):548-52. Review.

41.
42.

An essential role for p300/CBP in the cellular response to hypoxia.

Arany Z, Huang LE, Eckner R, Bhattacharya S, Jiang C, Goldberg MA, Bunn HF, Livingston DM.

Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):12969-73.

43.

Pitfalls of genetic testing.

Bunn HF, Stossel TP, Forget BG, Stamatoyannopoulos G, Weatherall DJ.

N Engl J Med. 1996 Oct 17;335(16):1236; author reply 1236-7. No abstract available.

PMID:
8999325
44.

Oxygen sensing and molecular adaptation to hypoxia.

Bunn HF, Poyton RO.

Physiol Rev. 1996 Jul;76(3):839-85. Review.

PMID:
8757790
45.
46.

Educating the biomedical scientist.

Bunn HF, Casey CG.

FASEB J. 1995 Nov;9(14):1392-5. No abstract available.

PMID:
7589979
47.

Use of a marked erythropoietin gene for investigation of its cis-acting elements.

Ho V, Acquaviva A, Duh E, Bunn HF.

J Biol Chem. 1995 Apr 28;270(17):10084-90.

49.

Regulation of erythropoietin gene expression.

Huang LE, Bunn HF.

Curr Opin Hematol. 1995 Mar;2(2):125-31. Review.

PMID:
9371982
50.

The role of hemoglobin based blood substitutes in transfusion medicine.

Bunn HF.

Transfus Clin Biol. 1995;2(6):433-9.

PMID:
8646338

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