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Items: 24


SDHC epi-mutation testing in gastrointestinal stromal tumours and related tumours in clinical practice.

Casey RT, Ten Hoopen R, Ochoa E, Challis BG, Whitworth J, Smith PS, Martin JE, Clark GR, Rodger F, Maranian M, Allinson K, Madhu B, Roberts T, Campos L, Anstee J, Park SM, Marker A, Watts C, Bulusu VR, Giger OT, Maher ER.

Sci Rep. 2019 Jul 15;9(1):10244. doi: 10.1038/s41598-019-46124-9.


Translating in vivo metabolomic analysis of succinate dehydrogenase deficient tumours into clinical utility.

Casey RT, McLean MA, Madhu B, Challis BG, Ten Hoopen R, Roberts T, Clark GR, Pittfield D, Simpson HL, Bulusu VR, Allinson K, Happerfield L, Park SM, Marker A, Giger O, Maher ER, Gallagher FA.

JCO Precis Oncol. 2018 Mar 29;2:1-12. doi: 10.1200/PO.17.00191.


A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression.

Auciello FR, Bulusu V, Oon C, Tait-Mulder J, Berry M, Bhattacharyya S, Tumanov S, Allen-Petersen BL, Link J, Kendsersky ND, Vringer E, Schug M, Novo D, Hwang RF, Evans RM, Nixon C, Dorrell C, Morton JP, Norman JC, Sears RC, Kamphorst JJ, Sherman MH.

Cancer Discov. 2019 May;9(5):617-627. doi: 10.1158/2159-8290.CD-18-1212. Epub 2019 Mar 5.


SDHA related tumorigenesis: a new case series and literature review for variant interpretation and pathogenicity.

Casey RT, Ascher DB, Rattenberry E, Izatt L, Andrews KA, Simpson HL, Challis B, Park SM, Bulusu VR, Lalloo F, Pires DEV, West H, Clark GR, Smith PS, Whitworth J, Papathomas TG, Taniere P, Savisaar R, Hurst LD, Woodward ER, Maher ER.

Mol Genet Genomic Med. 2017 Mar 2;5(3):237-250. doi: 10.1002/mgg3.279. eCollection 2017 May.


Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.

Bulusu V, Prior N, Snaebjornsson MT, Kuehne A, Sonnen KF, Kress J, Stein F, Schultz C, Sauer U, Aulehla A.

Dev Cell. 2017 Feb 27;40(4):331-341.e4. doi: 10.1016/j.devcel.2017.01.015.


Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation.

Bulusu V, Tumanov S, Michalopoulou E, van den Broek NJ, MacKay G, Nixon C, Dhayade S, Schug ZT, Vande Voorde J, Blyth K, Gottlieb E, Vazquez A, Kamphorst JJ.

Cell Rep. 2017 Jan 17;18(3):647-658. doi: 10.1016/j.celrep.2016.12.055.


Metabolic Control of Cellular Differentiation.

Bulusu V, Aulehla A.

Dev Cell. 2016 Nov 7;39(3):286-287. doi: 10.1016/j.devcel.2016.10.019.


A rapid method for quantifying free and bound acetate based on alkylation and GC-MS analysis.

Tumanov S, Bulusu V, Gottlieb E, Kamphorst JJ.

Cancer Metab. 2016 Sep 2;4(1):17. doi: 10.1186/s40170-016-0157-5. eCollection 2016.


Metabolic scavenging by cancer cells: when the going gets tough, the tough keep eating.

Michalopoulou E, Bulusu V, Kamphorst JJ.

Br J Cancer. 2016 Sep 6;115(6):635-40. doi: 10.1038/bjc.2016.256. Epub 2016 Aug 18. Review.


Global epidemiology of gastrointestinal stromal tumours (GIST): A systematic review of population-based cohort studies.

Søreide K, Sandvik OM, Søreide JA, Giljaca V, Jureckova A, Bulusu VR.

Cancer Epidemiol. 2016 Feb;40:39-46. doi: 10.1016/j.canep.2015.10.031. Epub 2015 Nov 24. Review.


Analysis of Fatty Acid Metabolism Using Stable Isotope Tracers and Mass Spectrometry.

Tumanov S, Bulusu V, Kamphorst JJ.

Methods Enzymol. 2015;561:197-217. doi: 10.1016/bs.mie.2015.05.017. Epub 2015 Aug 17. Review.


Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.

Cardaci S, Zheng L, MacKay G, van den Broek NJ, MacKenzie ED, Nixon C, Stevenson D, Tumanov S, Bulusu V, Kamphorst JJ, Vazquez A, Fleming S, Schiavi F, Kalna G, Blyth K, Strathdee D, Gottlieb E.

Nat Cell Biol. 2015 Oct;17(10):1317-26. doi: 10.1038/ncb3233. Epub 2015 Aug 24.


Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress.

Schug ZT, Peck B, Jones DT, Zhang Q, Grosskurth S, Alam IS, Goodwin LM, Smethurst E, Mason S, Blyth K, McGarry L, James D, Shanks E, Kalna G, Saunders RE, Jiang M, Howell M, Lassailly F, Thin MZ, Spencer-Dene B, Stamp G, van den Broek NJ, Mackay G, Bulusu V, Kamphorst JJ, Tardito S, Strachan D, Harris AL, Aboagye EO, Critchlow SE, Wakelam MJ, Schulze A, Gottlieb E.

Cancer Cell. 2015 Jan 12;27(1):57-71. doi: 10.1016/j.ccell.2014.12.002.


Masitinib in advanced gastrointestinal stromal tumor (GIST) after failure of imatinib: a randomized controlled open-label trial.

Adenis A, Blay JY, Bui-Nguyen B, Bouché O, Bertucci F, Isambert N, Bompas E, Chaigneau L, Domont J, Ray-Coquard I, Blésius A, Van Tine BA, Bulusu VR, Dubreuil P, Mansfield CD, Acin Y, Moussy A, Hermine O, Le Cesne A.

Ann Oncol. 2014 Sep;25(9):1762-9. doi: 10.1093/annonc/mdu237. Epub 2014 Jul 25.


Rationale and design of a UK database for a rare cancer type: the GEM Registry for gastrointestinal stromal tumours.

Bulusu VR, Fullarton J, Leahy M, Morgan C, Rasheed A, Taniere P, Toh S, Verrill M, White J, Judson I.

Br J Cancer. 2013 Sep 17;109(6):1403-7. doi: 10.1038/bjc.2013.406. Epub 2013 Aug 20.


Mechanism of growth inhibition of intraerythrocytic stages of Plasmodium falciparum by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR).

Bulusu V, Thakur SS, Venkatachala R, Balaram H.

Mol Biochem Parasitol. 2011 May;177(1):1-11. doi: 10.1016/j.molbiopara.2011.01.001. Epub 2011 Jan 18.


Metabolic fate of fumarate, a side product of the purine salvage pathway in the intraerythrocytic stages of Plasmodium falciparum.

Bulusu V, Jayaraman V, Balaram H.

J Biol Chem. 2011 Mar 18;286(11):9236-45. doi: 10.1074/jbc.M110.173328. Epub 2011 Jan 5.


Adenine metabolism in Plasmodium falciparum.

Mehrotra S, Bopanna MP, Bulusu V, Balaram H.

Exp Parasitol. 2010 Jun;125(2):147-51. doi: 10.1016/j.exppara.2010.01.002. Epub 2010 Jan 20.


Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum.

Bulusu V, Srinivasan B, Bopanna MP, Balaram H.

Biochim Biophys Acta. 2009 Apr;1794(4):642-54. doi: 10.1016/j.bbapap.2008.11.021. Epub 2008 Dec 7.


A review of the surgical management of metastatic gastrointestinal stromal tumours (GISTs) on imatinib mesylate (Glivec).

Barnes G, Bulusu VR, Hardwick RH, Carroll N, Hatcher H, Earl HM, Save VE, Balan K, Jamieson NV.

Int J Surg. 2005;3(3):206-12. Epub 2005 Sep 12.


Irinotecan and 5-fluorouracil in colorectal cancer: time for a pause?

Bulusu VR.

Eur J Cancer. 1998 Feb;34(3):286-9. No abstract available.


Paclitaxel in advanced ovarian cancer: too much optimism?

Bulusu VR, Allerton R.

Gynecol Oncol. 1997 Aug;66(2):335-6. No abstract available.


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