Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 129

1.

Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines.

Woo XY, Srivastava A, Graber JH, Yadav V, Sarsani VK, Simons A, Beane G, Grubb S, Ananda G, Liu R, Stafford G, Chuang JH, Airhart SD, Karuturi RKM, George J, Bult CJ.

BMC Med Genomics. 2019 Jul 1;12(1):92. doi: 10.1186/s12920-019-0551-2.

2.

Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma.

Berlow NE, Rikhi R, Geltzeiler M, Abraham J, Svalina MN, Davis LE, Wise E, Mancini M, Noujaim J, Mansoor A, Quist MJ, Matlock KL, Goros MW, Hernandez BS, Doung YC, Thway K, Tsukahara T, Nishio J, Huang ET, Airhart S, Bult CJ, Gandour-Edwards R, Maki RG, Jones RL, Michalek JE, Milovancev M, Ghosh S, Pal R, Keller C.

BMC Cancer. 2019 Jun 17;19(1):593. doi: 10.1186/s12885-019-5681-6.

3.

Factors that influence response classifications in chemotherapy treated patient-derived xenografts (PDX).

Malcolm JE, Stearns TM, Airhart SD, Graber JH, Bult CJ.

PeerJ. 2019 Mar 28;7:e6586. doi: 10.7717/peerj.6586. eCollection 2019.

4.

Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response.

Recla JM, Bubier JA, Gatti DM, Ryan JL, Long KH, Robledo RF, Glidden NC, Hou G, Churchill GA, Maser RS, Zhang ZW, Young EE, Chesler EJ, Bult CJ.

Pain. 2019 Mar 27. doi: 10.1097/j.pain.0000000000001571. [Epub ahead of print]

PMID:
30925521
5.

High-resolution deconstruction of evolution induced by chemotherapy treatments in breast cancer xenografts.

Kim H, Kumar P, Menghi F, Noorbakhsh J, Cerveira E, Ryan M, Zhu Q, Ananda G, George J, Chen HC, Mockus S, Zhang C, Yang Y, Keck J, Karuturi RKM, Bult CJ, Lee C, Liu ET, Chuang JH.

Sci Rep. 2018 Dec 18;8(1):17937. doi: 10.1038/s41598-018-36184-8.

6.

PDX Finder: A portal for patient-derived tumor xenograft model discovery.

Conte N, Mason JC, Halmagyi C, Neuhauser S, Mosaku A, Yordanova G, Chatzipli A, Begley DA, Krupke DM, Parkinson H, Meehan TF, Bult CC.

Nucleic Acids Res. 2019 Jan 8;47(D1):D1073-D1079. doi: 10.1093/nar/gky984.

7.

Mouse Genome Database (MGD) 2019.

Bult CJ, Blake JA, Smith CL, Kadin JA, Richardson JE; Mouse Genome Database Group .

Nucleic Acids Res. 2019 Jan 8;47(D1):D801-D806. doi: 10.1093/nar/gky1056.

8.

Model organism data evolving in support of translational medicine.

Howe DG, Blake JA, Bradford YM, Bult CJ, Calvi BR, Engel SR, Kadin JA, Kaufman TC, Kishore R, Laulederkind SJF, Lewis SE, Moxon SAT, Richardson JE, Smith C.

Lab Anim (NY). 2018 Oct;47(10):277-289. doi: 10.1038/s41684-018-0150-4. Epub 2018 Sep 17. Review.

9.

Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects.

Volpi S, Bult CJ, Chisholm RL, Deverka PA, Ginsburg GS, Jacob HJ, Kasapi M, McLeod HL, Roden DM, Williams MS, Green ED, Rodriguez LL, Aronson S, Cavallari LH, Denny JC, Dressler LG, Johnson JA, Klein TE, Leeder JS, Piquette-Miller M, Perera M, Rasmussen-Torvik LJ, Rehm HL, Ritchie MD, Skaar TC, Wagle N, Weinshilboum R, Weitzel KW, Wildin R, Wilson J, Manolio TA, Relling MV.

Clin Pharmacol Ther. 2018 May;103(5):778-786. doi: 10.1002/cpt.1048. Epub 2018 Mar 30. Review.

10.

Consensus coding sequence (CCDS) database: a standardized set of human and mouse protein-coding regions supported by expert curation.

Pujar S, O'Leary NA, Farrell CM, Loveland JE, Mudge JM, Wallin C, Girón CG, Diekhans M, Barnes I, Bennett R, Berry AE, Cox E, Davidson C, Goldfarb T, Gonzalez JM, Hunt T, Jackson J, Joardar V, Kay MP, Kodali VK, Martin FJ, McAndrews M, McGarvey KM, Murphy M, Rajput B, Rangwala SH, Riddick LD, Seal RL, Suner MM, Webb D, Zhu S, Aken BL, Bruford EA, Bult CJ, Frankish A, Murphy T, Pruitt KD.

Nucleic Acids Res. 2018 Jan 4;46(D1):D221-D228. doi: 10.1093/nar/gkx1031.

11.

The Mouse Tumor Biology Database: A Comprehensive Resource for Mouse Models of Human Cancer.

Krupke DM, Begley DA, Sundberg JP, Richardson JE, Neuhauser SB, Bult CJ.

Cancer Res. 2017 Nov 1;77(21):e67-e70. doi: 10.1158/0008-5472.CAN-17-0584.

12.

PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.

Meehan TF, Conte N, Goldstein T, Inghirami G, Murakami MA, Brabetz S, Gu Z, Wiser JA, Dunn P, Begley DA, Krupke DM, Bertotti A, Bruna A, Brush MH, Byrne AT, Caldas C, Christie AL, Clark DA, Dowst H, Dry JR, Doroshow JH, Duchamp O, Evrard YA, Ferretti S, Frese KK, Goodwin NC, Greenawalt D, Haendel MA, Hermans E, Houghton PJ, Jonkers J, Kemper K, Khor TO, Lewis MT, Lloyd KCK, Mason J, Medico E, Neuhauser SB, Olson JM, Peeper DS, Rueda OM, Seong JK, Trusolino L, Vinolo E, Wechsler-Reya RJ, Weinstock DM, Welm A, Weroha SJ, Amant F, Pfister SM, Kool M, Parkinson H, Butte AJ, Bult CJ.

Cancer Res. 2017 Nov 1;77(21):e62-e66. doi: 10.1158/0008-5472.CAN-17-0582.

13.

Mouse Genome Database (MGD)-2018: knowledgebase for the laboratory mouse.

Smith CL, Blake JA, Kadin JA, Richardson JE, Bult CJ; Mouse Genome Database Group.

Nucleic Acids Res. 2018 Jan 4;46(D1):D836-D842. doi: 10.1093/nar/gkx1006.

14.

EphB4/EphrinB2 therapeutics in Rhabdomyosarcoma.

Randolph ME, Cleary MM, Bajwa Z, Svalina MN, Young MC, Mansoor A, Kaur P, Bult CJ, Goros MW, Michalek JE, Xiang S, Keck J, Krasnoperov V, Gill P, Keller C.

PLoS One. 2017 Aug 17;12(8):e0183161. doi: 10.1371/journal.pone.0183161. eCollection 2017.

15.

Editorial overview: Characterizing the cancer genome: mechanistic insights and translational opportunities.

Delattre O, Bult CJ.

Curr Opin Genet Dev. 2017 Feb;42:78-80. doi: 10.1016/j.gde.2017.04.001. Epub 2017 Apr 15. No abstract available.

PMID:
28419908
16.

Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research.

Manolio TA, Fowler DM, Starita LM, Haendel MA, MacArthur DG, Biesecker LG, Worthey E, Chisholm RL, Green ED, Jacob HJ, McLeod HL, Roden D, Rodriguez LL, Williams MS, Cooper GM, Cox NJ, Herman GE, Kingsmore S, Lo C, Lutz C, MacRae CA, Nussbaum RL, Ordovas JM, Ramos EM, Robinson PN, Rubinstein WS, Seidman C, Stranger BE, Wang H, Westerfield M, Bult C.

Cell. 2017 Mar 23;169(1):6-12. doi: 10.1016/j.cell.2017.03.005.

17.

Genome-wide enrichment of damaging de novo variants in patients with isolated and complex congenital diaphragmatic hernia.

Longoni M, High FA, Qi H, Joy MP, Hila R, Coletti CM, Wynn J, Loscertales M, Shan L, Bult CJ, Wilson JM, Shen Y, Chung WK, Donahoe PK.

Hum Genet. 2017 Jun;136(6):679-691. doi: 10.1007/s00439-017-1774-y. Epub 2017 Mar 16.

18.

Patient-derived xenograft (PDX) models in basic and translational breast cancer research.

Dobrolecki LE, Airhart SD, Alferez DG, Aparicio S, Behbod F, Bentires-Alj M, Brisken C, Bult CJ, Cai S, Clarke RB, Dowst H, Ellis MJ, Gonzalez-Suarez E, Iggo RD, Kabos P, Li S, Lindeman GJ, Marangoni E, McCoy A, Meric-Bernstam F, Piwnica-Worms H, Poupon MF, Reis-Filho J, Sartorius CA, Scabia V, Sflomos G, Tu Y, Vaillant F, Visvader JE, Welm A, Wicha MS, Lewis MT.

Cancer Metastasis Rev. 2016 Dec;35(4):547-573. doi: 10.1007/s10555-016-9653-x. Review.

19.

Mouse Genome Informatics (MGI): Resources for Mining Mouse Genetic, Genomic, and Biological Data in Support of Primary and Translational Research.

Eppig JT, Smith CL, Blake JA, Ringwald M, Kadin JA, Richardson JE, Bult CJ.

Methods Mol Biol. 2017;1488:47-73.

PMID:
27933520
20.

Mouse Genome Database (MGD)-2017: community knowledge resource for the laboratory mouse.

Blake JA, Eppig JT, Kadin JA, Richardson JE, Smith CL, Bult CJ; the Mouse Genome Database Group.

Nucleic Acids Res. 2017 Jan 4;45(D1):D723-D729. doi: 10.1093/nar/gkw1040. Epub 2016 Nov 28.

21.

Temporal dynamics of the developing lung transcriptome in three common inbred strains of laboratory mice reveals multiple stages of postnatal alveolar development.

Beauchemin KJ, Wells JM, Kho AT, Philip VM, Kamir D, Kohane IS, Graber JH, Bult CJ.

PeerJ. 2016 Aug 9;4:e2318. doi: 10.7717/peerj.2318. eCollection 2016.

22.

De novo frameshift mutation in COUP-TFII (NR2F2) in human congenital diaphragmatic hernia.

High FA, Bhayani P, Wilson JM, Bult CJ, Donahoe PK, Longoni M.

Am J Med Genet A. 2016 Sep;170(9):2457-61. doi: 10.1002/ajmg.a.37830. Epub 2016 Jul 1.

23.

Metabolite profile of a mouse model of Charcot-Marie-Tooth type 2D neuropathy: implications for disease mechanisms and interventions.

Bais P, Beebe K, Morelli KH, Currie ME, Norberg SN, Evsikov AV, Miers KE, Seburn KL, Guergueltcheva V, Kremensky I, Jordanova A, Bult CJ, Burgess RW.

Biol Open. 2016 Jul 15;5(7):908-20. doi: 10.1242/bio.019273.

24.

Current state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop.

Hingorani P, Janeway K, Crompton BD, Kadoch C, Mackall CL, Khan J, Shern JF, Schiffman J, Mirabello L, Savage SA, Ladanyi M, Meltzer P, Bult CJ, Adamson PC, Lupo PJ, Mody R, DuBois SG, Parsons DW, Khanna C, Lau C, Hawkins DS, Randall RL, Smith M, Sorensen PH, Plon SE, Skapek SX, Lessnick S, Gorlick R, Reed DR.

Cancer Genet. 2016 May;209(5):182-94. doi: 10.1016/j.cancergen.2016.03.004. Epub 2016 Apr 5. Review.

25.

Patient-Derived Tumor Xenografts: Why Now?

Liu ET, Bult CJ, Shultz LD.

JAMA Oncol. 2016 May 1;2(5):567-568. doi: 10.1001/jamaoncol.2016.0193. No abstract available.

PMID:
27055176
26.

R2d2 Drives Selfish Sweeps in the House Mouse.

Didion JP, Morgan AP, Yadgary L, Bell TA, McMullan RC, Ortiz de Solorzano L, Britton-Davidian J, Bult CJ, Campbell KJ, Castiglia R, Ching YH, Chunco AJ, Crowley JJ, Chesler EJ, Förster DW, French JE, Gabriel SI, Gatti DM, Garland T Jr, Giagia-Athanasopoulou EB, Giménez MD, Grize SA, Gündüz İ, Holmes A, Hauffe HC, Herman JS, Holt JM, Hua K, Jolley WJ, Lindholm AK, López-Fuster MJ, Mitsainas G, da Luz Mathias M, McMillan L, Ramalhinho Mda G, Rehermann B, Rosshart SP, Searle JB, Shiao MS, Solano E, Svenson KL, Thomas-Laemont P, Threadgill DW, Ventura J, Weinstock GM, Pomp D, Churchill GA, Pardo-Manuel de Villena F.

Mol Biol Evol. 2016 Jun;33(6):1381-95. doi: 10.1093/molbev/msw036. Epub 2016 Feb 15.

27.

A Patient-Derived Xenograft Model of Parameningeal Embryonal Rhabdomyosarcoma for Preclinical Studies.

Hooper JE, Cantor EL, Ehlen MS, Banerjee A, Malempati S, Stenzel P, Woltjer RL, Gandour-Edwards R, Goodwin NC, Yang Y, Kaur P, Bult CJ, Airhart SD, Keller C.

Sarcoma. 2015;2015:826124. doi: 10.1155/2015/826124. Epub 2015 Nov 30.

28.

Clinical Trials in Precision Oncology.

Mockus SM, Patterson SE, Statz C, Bult CJ, Tsongalis GJ.

Clin Chem. 2016 Mar;62(3):442-8. doi: 10.1373/clinchem.2015.247437. Epub 2015 Nov 25. Review.

29.

Mouse genome database 2016.

Bult CJ, Eppig JT, Blake JA, Kadin JA, Richardson JE; Mouse Genome Database Group.

Nucleic Acids Res. 2016 Jan 4;44(D1):D840-7. doi: 10.1093/nar/gkv1211. Epub 2015 Nov 17.

30.

Finding mouse models of human lymphomas and leukemia's using the Jackson laboratory mouse tumor biology database.

Begley DA, Sundberg JP, Krupke DM, Neuhauser SB, Bult CJ, Eppig JT, Morse HC 3rd, Ward JM.

Exp Mol Pathol. 2015 Dec;99(3):533-6. doi: 10.1016/j.yexmp.2015.07.004. Epub 2015 Aug 21.

31.

Development and Characterization of Bladder Cancer Patient-Derived Xenografts for Molecularly Guided Targeted Therapy.

Pan CX, Zhang H, Tepper CG, Lin TY, Davis RR, Keck J, Ghosh PM, Gill P, Airhart S, Bult C, Gandara DR, Liu E, de Vere White RW.

PLoS One. 2015 Aug 13;10(8):e0134346. doi: 10.1371/journal.pone.0134346. eCollection 2015.

32.

Mouse Genome Informatics (MGI): reflecting on 25 years.

Eppig JT, Richardson JE, Kadin JA, Ringwald M, Blake JA, Bult CJ.

Mamm Genome. 2015 Aug;26(7-8):272-84. doi: 10.1007/s00335-015-9589-4. Epub 2015 Aug 4. Review.

33.

Orthology for comparative genomics in the mouse genome database.

Dolan ME, Baldarelli RM, Bello SM, Ni L, McAndrews MS, Bult CJ, Kadin JA, Richardson JE, Ringwald M, Eppig JT, Blake JA.

Mamm Genome. 2015 Aug;26(7-8):305-13. doi: 10.1007/s00335-015-9588-5. Epub 2015 Jul 30. Review.

34.

Mouse Genome Database: From sequence to phenotypes and disease models.

Eppig JT, Richardson JE, Kadin JA, Smith CL, Blake JA, Bult CJ; MGD Team.

Genesis. 2015 Aug;53(8):458-73. doi: 10.1002/dvg.22874. Epub 2015 Jul 27. Review.

35.

A unified gene catalog for the laboratory mouse reference genome.

Zhu Y, Richardson JE, Hale P, Baldarelli RM, Reed DJ, Recla JM, Sinclair R, Reddy TB, Bult CJ.

Mamm Genome. 2015 Aug;26(7-8):295-304. doi: 10.1007/s00335-015-9571-1. Epub 2015 Jun 18.

36.

Visual annotation display (VLAD): a tool for finding functional themes in lists of genes.

Richardson JE, Bult CJ.

Mamm Genome. 2015 Oct;26(9-10):567-73. doi: 10.1007/s00335-015-9570-2. Epub 2015 Jun 6.

37.

Bridging tumor genomics to patient outcomes through an integrated patient-derived xenograft platform.

Gandara DR, Mack PC, Bult C, Li T, Lara PN Jr, Riess JW, Astrow SH, Gandour-Edwards R, Cooke DT, Yoneda KY, Moore EH, Pan CX, Burich RA, David EA, Keck JG, Airhart S, Goodwin N, de Vere White RW, Liu ET.

Clin Lung Cancer. 2015 May;16(3):165-72. doi: 10.1016/j.cllc.2015.03.001. Epub 2015 Mar 18.

38.

Development and validation of the JAX Cancer Treatment Profile™ for detection of clinically actionable mutations in solid tumors.

Ananda G, Mockus S, Lundquist M, Spotlow V, Simons A, Mitchell T, Stafford G, Philip V, Stearns T, Srivastava A, Barter M, Rowe L, Malcolm J, Bult C, Karuturi RK, Rasmussen K, Hinerfeld D.

Exp Mol Pathol. 2015 Feb;98(1):106-12. doi: 10.1016/j.yexmp.2014.12.009. Epub 2015 Jan 3.

39.

The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease.

Eppig JT, Blake JA, Bult CJ, Kadin JA, Richardson JE; Mouse Genome Database Group.

Nucleic Acids Res. 2015 Jan;43(Database issue):D726-36. doi: 10.1093/nar/gku967. Epub 2014 Oct 27.

40.

Mouse Tumor Biology (MTB): a database of mouse models for human cancer.

Bult CJ, Krupke DM, Begley DA, Richardson JE, Neuhauser SB, Sundberg JP, Eppig JT.

Nucleic Acids Res. 2015 Jan;43(Database issue):D818-24. doi: 10.1093/nar/gku987. Epub 2014 Oct 20.

41.

Molecular pathogenesis of congenital diaphragmatic hernia revealed by exome sequencing, developmental data, and bioinformatics.

Longoni M, High FA, Russell MK, Kashani A, Tracy AA, Coletti CM, Hila R, Shamia A, Wells J, Ackerman KG, Wilson JM, Bult CJ, Lee C, Lage K, Pober BR, Donahoe PK.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12450-5. doi: 10.1073/pnas.1412509111. Epub 2014 Aug 8.

42.

Identifying mouse models for skin cancer using the Mouse Tumor Biology Database.

Begley DA, Krupke DM, Neuhauser SB, Richardson JE, Schofield PN, Bult CJ, Eppig JT, Sundberg JP.

Exp Dermatol. 2014 Oct;23(10):761-3. doi: 10.1111/exd.12512.

43.

Precise genetic mapping and integrative bioinformatics in Diversity Outbred mice reveals Hydin as a novel pain gene.

Recla JM, Robledo RF, Gatti DM, Bult CJ, Churchill GA, Chesler EJ.

Mamm Genome. 2014 Jun;25(5-6):211-22. doi: 10.1007/s00335-014-9508-0. Epub 2014 Apr 5.

44.

The Mouse Genome Database: integration of and access to knowledge about the laboratory mouse.

Blake JA, Bult CJ, Eppig JT, Kadin JA, Richardson JE; Mouse Genome Database Group.

Nucleic Acids Res. 2014 Jan;42(Database issue):D810-7. doi: 10.1093/nar/gkt1225. Epub 2013 Nov 26.

45.

Protein Ontology: a controlled structured network of protein entities.

Natale DA, Arighi CN, Blake JA, Bult CJ, Christie KR, Cowart J, D'Eustachio P, Diehl AD, Drabkin HJ, Helfer O, Huang H, Masci AM, Ren J, Roberts NV, Ross K, Ruttenberg A, Shamovsky V, Smith B, Yerramalla MS, Zhang J, AlJanahi A, Çelen I, Gan C, Lv M, Schuster-Lezell E, Wu CH.

Nucleic Acids Res. 2014 Jan;42(Database issue):D415-21. doi: 10.1093/nar/gkt1173. Epub 2013 Nov 21.

46.

Mouse phenome database.

Grubb SC, Bult CJ, Bogue MA.

Nucleic Acids Res. 2014 Jan;42(Database issue):D825-34. doi: 10.1093/nar/gkt1159. Epub 2013 Nov 15.

47.

High-precision genetic mapping of behavioral traits in the diversity outbred mouse population.

Logan RW, Robledo RF, Recla JM, Philip VM, Bubier JA, Jay JJ, Harwood C, Wilcox T, Gatti DM, Bult CJ, Churchill GA, Chesler EJ.

Genes Brain Behav. 2013 Jun;12(4):424-37. doi: 10.1111/gbb.12029. Epub 2013 Mar 20.

48.

Bioinformatics resources for behavior studies in the laboratory mouse.

Bult CJ.

Int Rev Neurobiol. 2012;104:71-90. doi: 10.1016/B978-0-12-398323-7.00004-5. Review.

PMID:
23195312
49.

The mouse genome database: genotypes, phenotypes, and models of human disease.

Bult CJ, Eppig JT, Blake JA, Kadin JA, Richardson JE; Mouse Genome Database Group.

Nucleic Acids Res. 2013 Jan;41(Database issue):D885-91. doi: 10.1093/nar/gks1115. Epub 2012 Nov 21.

50.

Tissue-specific functional networks for prioritizing phenotype and disease genes.

Guan Y, Gorenshteyn D, Burmeister M, Wong AK, Schimenti JC, Handel MA, Bult CJ, Hibbs MA, Troyanskaya OG.

PLoS Comput Biol. 2012;8(9):e1002694. doi: 10.1371/journal.pcbi.1002694. Epub 2012 Sep 27.

Supplemental Content

Support Center