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Caring for Patients Treated With Checkpoint Inhibitors for the Treatment of Metastatic Merkel Cell Carcinoma.

Rubin KM, Hoffner B, Bullock AC.

Semin Oncol Nurs. 2019 Sep 9:150924. doi: 10.1016/j.soncn.2019.08.003. [Epub ahead of print] Review.


Angiogenic Factor and Cytokine Analysis among Patients Treated with Adjuvant VEGFR TKIs in Resected Renal Cell Carcinoma.

Xu W, Puligandla M, Manola J, Bullock AJ, Tamasauskas D, McDermott DF, Atkins MB, Haas NB, Flaherty K, Uzzo RG, Dutcher JP, DiPaola RS, Bhatt RS.

Clin Cancer Res. 2019 Aug 30. doi: 10.1158/1078-0432.CCR-19-0818. [Epub ahead of print]


Target highlights in CASP13: Experimental target structures through the eyes of their authors.

Lepore R, Kryshtafovych A, Alahuhta M, Veraszto HA, Bomble YJ, Bufton JC, Bullock AN, Caba C, Cao H, Davies OR, Desfosses A, Dunne M, Fidelis K, Goulding CW, Gurusaran M, Gutsche I, Harding CJ, Hartmann MD, Hayes CS, Joachimiak A, Leiman PG, Loppnau P, Lovering AL, Lunin VV, Michalska K, Mir-Sanchis I, Mitra A, Moult J, Phillips GN Jr, Pinkas DM, Rice PA, Tong Y, Topf M, Walton JD, Schwede T.

Proteins. 2019 Aug 23. doi: 10.1002/prot.25805. [Epub ahead of print]


Erratum. Regression to Normal Glucose Regulation in American Indians and Alaska Natives of a Diabetes Prevention Program. Diabetes Care 2019;42:1209-1216.

Pratte KA, Johnson A, Beals J, Bullock A, Manson SM, Jiang L; Special Diabetes Program for Indians Diabetes Prevention Program.

Diabetes Care. 2019 Aug 20. pii: dc19er10. doi: 10.2337/dc19-er10. [Epub ahead of print] No abstract available.


"I didn't realise they had such a key role." Impact of medical education curriculum change on medical student interactions with nurses: a qualitative exploratory study of student perceptions.

Samuriwo R, Laws E, Webb K, Bullock A.

Adv Health Sci Educ Theory Pract. 2019 Aug 7. doi: 10.1007/s10459-019-09906-4. [Epub ahead of print]


Kinetic Control of [AuCl4]- Photochemical Reduction and Gold Nanoparticle Size with Hydroxyl Radical Scavengers.

Frias Batista LM, Meader VK, Romero K, Kunzler K, Kabir F, Bullock A, Tibbetts KM.

J Phys Chem B. 2019 Aug 22;123(33):7204-7213. doi: 10.1021/acs.jpcb.9b04643. Epub 2019 Aug 9.


A randomized phase II trial of nab-paclitaxel and gemcitabine with tarextumab or placebo in patients with untreated metastatic pancreatic cancer.

Hu ZI, Bendell JC, Bullock A, LoConte NK, Hatoum H, Ritch P, Hool H, Leach JW, Sanchez J, Sohal DPS, Strickler J, Patel R, Wang-Gillam A, Firdaus I, Yu KH, Kapoun AM, Holmgren E, Zhou L, Dupont J, Picozzi V, Sahai V, O'Reilly EM.

Cancer Med. 2019 Sep;8(11):5148-5157. doi: 10.1002/cam4.2425. Epub 2019 Jul 26.


SAGE-217, A Novel GABAA Receptor Positive Allosteric Modulator: Clinical Pharmacology and Tolerability in Randomized Phase I Dose-Finding Studies.

Hoffmann E, Nomikos GG, Kaul I, Raines S, Wald J, Bullock A, Sankoh AJ, Doherty J, Kanes SJ, Colquhoun H.

Clin Pharmacokinet. 2019 Jul 24. doi: 10.1007/s40262-019-00801-0. [Epub ahead of print]


2-Amino-2,3-dihydro-1H-indene-5-carboxamide-Based Discoidin Domain Receptor 1 (DDR1) Inhibitors: Design, Synthesis, and in Vivo Antipancreatic Cancer Efficacy.

Zhu D, Huang H, Pinkas DM, Luo J, Ganguly D, Fox AE, Arner E, Xiang Q, Tu ZC, Bullock AN, Brekken RA, Ding K, Lu X.

J Med Chem. 2019 Aug 22;62(16):7431-7444. doi: 10.1021/acs.jmedchem.9b00365. Epub 2019 Aug 2.


Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma.

Noel M, O'Reilly EM, Wolpin BM, Ryan DP, Bullock AJ, Britten CD, Linehan DC, Belt BA, Gamelin EC, Ganguly B, Yin D, Joh T, Jacobs IA, Taylor CT, Lowery MA.

Invest New Drugs. 2019 Jul 12. doi: 10.1007/s10637-019-00830-3. [Epub ahead of print]


Reply to Wouthuyzen-Bakker, et al.

Shah NB, Hersh BL, Kreger A, Sayeed A, Bullock AG, Rothenberger SD, Klatt B, Hamlin B, Urish KL.

Clin Infect Dis. 2019 Jul 10. pii: ciz632. doi: 10.1093/cid/ciz632. [Epub ahead of print] No abstract available.


Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase.

Chen Z, Picaud S, Filippakopoulos P, D'Angiolella V, Bullock AN.

Structure. 2019 Sep 3;27(9):1395-1404.e4. doi: 10.1016/j.str.2019.06.005. Epub 2019 Jul 3.


Social Problem Solving and Posttraumatic Growth New Possibilities in Postoperative Breast Cancer Survivors.

Markman ES, McClure KS, McMahon CE, Zelikovsky N, Macone BW, Bullock AJ.

J Clin Psychol Med Settings. 2019 Jun 18. doi: 10.1007/s10880-019-09641-3. [Epub ahead of print]


Regression to Normal Glucose Regulation in American Indians and Alaska Natives of a Diabetes Prevention Program.

Pratte KA, Johnson A, Beals J, Bullock A, Manson SM, Jiang L; and the Special Diabetes Program for Indians Diabetes Prevention Program.

Diabetes Care. 2019 Jul;42(7):1209-1216. doi: 10.2337/dc18-1964. Epub 2019 Jun 8. Erratum in: Diabetes Care. 2019 Aug 20;:.


Spontaneous regression of pancreatic cancer with liver metastases.

Saade Lemus P, Anderson K, Smith M, Bullock A.

BMJ Case Rep. 2019 May 31;12(5). pii: e229619. doi: 10.1136/bcr-2019-229619.


Effectiveness of postoperative radiotherapy after radical cystectomy for locally advanced bladder cancer.

Fischer-Valuck BW, Michalski JM, Mitra N, Christodouleas JP, DeWees TA, Kim E, Smith ZL, Andriole GL, Arora V, Bullock A, Carmona R, Figenshau RS, Grubb RL, Guzzo TJ, Knoche EM, Malkowicz SB, Mamtani R, Pachynski RK, Roth BJ, Zaghloul MS, Gay HA, Baumann BC.

Cancer Med. 2019 Jul;8(8):3698-3709. doi: 10.1002/cam4.2102. Epub 2019 May 22.


ALK2 inhibitors display beneficial effects in preclinical models of ACVR1 mutant diffuse intrinsic pontine glioma.

Carvalho D, Taylor KR, Olaciregui NG, Molinari V, Clarke M, Mackay A, Ruddle R, Henley A, Valenti M, Hayes A, Brandon AH, Eccles SA, Raynaud F, Boudhar A, Monje M, Popov S, Moore AS, Mora J, Cruz O, Vinci M, Brennan PE, Bullock AN, Carcaboso AM, Jones C.

Commun Biol. 2019 May 9;2:156. doi: 10.1038/s42003-019-0420-8. eCollection 2019.


Self-report versus objective measurement of weight history: implications for pre-treatment weight gain.

Phimphasone-Brady P, Dorflinger LM, Ruser C, Bullock A, Godfrey KM, Hernandez D, Min KM, Masheb RM.

J Behav Med. 2019 Apr 23. doi: 10.1007/s10865-019-00045-0. [Epub ahead of print]


Updates on HIV nonoccupational postexposure prophylaxis.

Koyama A, Middlebrooks L, Bullock A.

Curr Opin Pediatr. 2019 Aug;31(4):454-461. doi: 10.1097/MOP.0000000000000775.


Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer: The SUNSHINE Randomized Clinical Trial.

Ng K, Nimeiri HS, McCleary NJ, Abrams TA, Yurgelun MB, Cleary JM, Rubinson DA, Schrag D, Miksad R, Bullock AJ, Allen J, Zuckerman D, Chan E, Chan JA, Wolpin BM, Constantine M, Weckstein DJ, Faggen MA, Thomas CA, Kournioti C, Yuan C, Ganser C, Wilkinson B, Mackintosh C, Zheng H, Hollis BW, Meyerhardt JA, Fuchs CS.

JAMA. 2019 Apr 9;321(14):1370-1379. doi: 10.1001/jama.2019.2402.


Benefits and Adverse Events Associated with Extended Antibiotic Use in Total Knee Arthroplasty Periprosthetic Joint Infection.

Shah NB, Hersh BL, Kreger AM, Sayeed A, Bullock AG, Rothenberger SD, Klatt B, Hamlin B, Urish KL.

Clin Infect Dis. 2019 Apr 4. pii: ciz261. doi: 10.1093/cid/ciz261. [Epub ahead of print]


Spatiotemporal release of VEGF from biodegradable polylactic-co-glycolic acid microspheres induces angiogenesis in chick chorionic allantoic membrane assay.

Qutachi O, Bullock AJ, Gigliobianco G, MacNeil S.

Int J Pharm. 2019 Apr 20;561:236-243. doi: 10.1016/j.ijpharm.2019.03.015. Epub 2019 Mar 8.


Newly qualified doctors' perceived effects of assistantship alignment with first post: a longitudinal questionnaire study.

Wells SE, Bullock A, Monrouxe LV.

BMJ Open. 2019 Mar 3;9(3):e023992. doi: 10.1136/bmjopen-2018-023992.


Disciplinary boundaries and integrating care: using Q-methodology to understand trainee views on being a good doctor.

Muddiman E, Bullock AD, Hampton JM, Allery L, MacDonald J, Webb KL, Pugsley L.

BMC Med Educ. 2019 Feb 15;19(1):59. doi: 10.1186/s12909-019-1493-2.


Pacemakers are associated with a higher risk of late death and transplantation in the Fontan population.

Poh CL, Celermajer DS, Grigg LE, Kalman JM, McGuire MA, Gentles TL, Radford DJ, Bullock A, Disney PJS, Winlaw D, du Plessis K, d'Udekem Y.

Int J Cardiol. 2019 May 1;282:33-37. doi: 10.1016/j.ijcard.2019.01.088. Epub 2019 Jan 25.


Evaluating Community-Based Translational Interventions Using Historical Controls: Propensity Score vs. Disease Risk Score Approach.

Jiang L, Chen S, Beals J, Siddique J, Hamman RF, Bullock A, Manson SM; Special Diabetes Program for Indians Diabetes Prevention Demonstration Project; Grant programs participating in the Special Diabetes Program for Indians Diabetes Prevention Program are as follows: Confederated Tribes of the Chehalis Reservation, Cherokee Nation, Cheyenne River Sioux Tribe, the Chickasaw Nation, Coeur d’Alene Tribe, Colorado River Indian Tribes, Colville Confederated Tribes, Cow Creek Band of Umpqua Tribe, Klamath Tribes, and Coquille Tribe, Fond du Lac Reservation, Gila River Health Care, Haskell Health Center, Ho-Chunk Nation, Indian Health Board of Minneapolis, Indian Health Center of Santa Clara Valley, Native American Rehabilitation Association of the NW, Hunter Health, Kenaitze Indian Tribe IRA, Lawton IHS Service Unit, Menominee Indian Tribe of Wisconsin, Mississippi Band of Choctaw Indians, Norton Sound Health Corporation, Pine Ridge IHS Service Unit, Pueblo of San Felipe, Quinault Indian Nation, Rapid City IHS Diabetes Program, Red Lake Comprehensive Health Services, Rocky Boy Health Board, Seneca Nation of Indians, Sonoma County Indian Health Project, South East Alaska Regional Health Consortium, Southcentral Foundation, Trenton Indian Service Area, Tuba City Regional Health Care Corporation, United American Indian Involvement, Inc., United Indian Health Services, Inc., Warm Springs Health & Wellness Center, Winnebago Tribe of Nebraska, Zuni Pueblo.

Prev Sci. 2019 May;20(4):598-608. doi: 10.1007/s11121-019-0980-3.


A propensity analysis comparing definitive chemo-radiotherapy for muscle-invasive squamous cell carcinoma of the bladder vs. urothelial carcinoma of the bladder using the National Cancer Database.

Fischer-Valuck BW, Michalski JM, Contreras JA, Brenneman R, Christodouleas JP, Abraham CD, Kim EH, Arora VK, Bullock AD, Carmona R, Figenshau RS, Grubb R 3rd, Knoche EM, Pachynski RK, Picus J, Roth BJ, Sargos P, Andriole GL, Gay HA, Baumann BC.

Clin Transl Radiat Oncol. 2018 Dec 12;15:38-41. doi: 10.1016/j.ctro.2018.12.001. eCollection 2019 Feb.


Emotional socialisation and burnout in medicine and the role of medical educators.

Laws E, Samuriwo R, Webb K, Bullock A.

Med Educ. 2019 Apr;53(4):320-322. doi: 10.1111/medu.13787. Epub 2019 Jan 15. No abstract available.


Augmentation of the pulmonary arteries at or prior to the Fontan procedure is not associated with worse long-term outcomes: a propensity-matched analysis from the Australia-New Zealand Fontan Registry†.

Shearer L, Justo RN, Marathe SP, Betts K, Venugopal P, Winlaw DS, Bullock A, Robertson T, Gentles TL, Celermajer D, d'Udekem Y, Alphonso N.

Eur J Cardiothorac Surg. 2019 May 1;55(5):829-836. doi: 10.1093/ejcts/ezy376.


Adult Congenital Heart Disease in Australia and New Zealand: A Call for Optimal Care.

Nicolae M, Gentles T, Strange G, Tanous D, Disney P, Bullock A, Grigg L, Chen SSM, Pressley L, Cordina R, Hornung T, O'Donnell C, Celermajer DS.

Heart Lung Circ. 2019 Apr;28(4):521-529. doi: 10.1016/j.hlc.2018.10.015. Epub 2018 Oct 28. Review.


Dietary protein restriction reduces circulating VLDL triglyceride levels via CREBH-APOA5-dependent and -independent mechanisms.

Treviño-Villarreal JH, Reynolds JS, Bartelt A, Langston PK, MacArthur MR, Arduini A, Tosti V, Veronese N, Bertozzi B, Brace LE, Mejia P, Trocha K, Kajitani GS, Longchamp A, Harputlugil E, Gathungu R, Bird SS, Bullock AD, Figenshau RS, Andriole GL, Thompson A, Heeren J, Ozaki CK, Kristal BS, Fontana L, Mitchell JR.

JCI Insight. 2018 Nov 2;3(21). pii: 99470. doi: 10.1172/jci.insight.99470.


Ablation of Atrial Arrhythmias After the Atriopulmonary Fontan Procedure: Mechanisms of Arrhythmia and Outcomes.

Moore BM, Anderson R, Nisbet AM, Kalla M, du Plessis K, d'Udekem Y, Bullock A, Cordina RL, Grigg L, Celermajer DS, Kalman J, McGuire MA.

JACC Clin Electrophysiol. 2018 Oct;4(10):1338-1346. doi: 10.1016/j.jacep.2018.08.012.


A Prospective, Single-Blind, Randomized, Phase III Study to Evaluate the Safety and Efficacy of Fibrin Sealant Grifols as an Adjunct to Hemostasis During Soft Tissue Open Surgery.

Lakshman S, Aqua K, Stefanovic A, Djurdjevic S, Nyirády P, Osváth P, Davis R, Bullock A, Chen J, Ibañez J, Barrera G, Navarro-Puerto J; Fibrin Sealant Grifols in Soft Tissue Surgery Study Clinical Investigation Group.

J Invest Surg. 2018 Oct 10:1-13. doi: 10.1080/08941939.2018.1489917. [Epub ahead of print]


Surgical Management for Prostate Cancer.

Kim EH, Bullock AD.

Mo Med. 2018 Mar-Apr;115(2):142-145.


A Phase II and Biomarker Study of Sorafenib Combined with Modified FOLFOX in Patients with Advanced Hepatocellular Carcinoma.

Goyal L, Zheng H, Abrams TA, Miksad R, Bullock AJ, Allen JN, Yurgelun MB, Clark JW, Kambadakone A, Muzikansky A, Knowles M, Galway A, Afflitto AJ, Dinicola CF, Regan E, Hato T, Mamessier E, Shigeta K, Jain RK, Duda DG, Zhu AX.

Clin Cancer Res. 2019 Jan 1;25(1):80-89. doi: 10.1158/1078-0432.CCR-18-0847. Epub 2018 Sep 6.


New graduate doctors' preparedness for practice: a multistakeholder, multicentre narrative study.

Monrouxe LV, Bullock A, Gormley G, Kaufhold K, Kelly N, Roberts CE, Mattick K, Rees C.

BMJ Open. 2018 Aug 29;8(8):e023146. doi: 10.1136/bmjopen-2018-023146.


Exercise training improves vascular function and secondary health measures in survivors of pediatric oncology related cerebral insult.

Long TM, Rath SR, Wallman KE, Howie EK, Straker LM, Bullock A, Walwyn TS, Gottardo NG, Cole CH, Choong CS, Naylor LH.

PLoS One. 2018 Aug 9;13(8):e0201449. doi: 10.1371/journal.pone.0201449. eCollection 2018.


Novel Quinazolinone Inhibitors of ALK2 Flip between Alternate Binding Modes: Structure-Activity Relationship, Structural Characterization, Kinase Profiling, and Cellular Proof of Concept.

Hudson L, Mui J, Vázquez S, Carvalho DM, Williams E, Jones C, Bullock AN, Hoelder S.

J Med Chem. 2018 Aug 23;61(16):7261-7272. doi: 10.1021/acs.jmedchem.8b00782. Epub 2018 Aug 7.


Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2- a]pyrazin-3-ylethynyl)-4-isopropyl- N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2.

Wang Z, Zhang Y, Pinkas DM, Fox AE, Luo J, Huang H, Cui S, Xiang Q, Xu T, Xun Q, Zhu D, Tu Z, Ren X, Brekken RA, Bullock AN, Liang G, Ding K, Lu X.

J Med Chem. 2018 Sep 13;61(17):7977-7990. doi: 10.1021/acs.jmedchem.8b01045. Epub 2018 Aug 20.


The role of adolescents' perceived parental psychological control in the links between shyness and socio-emotional adjustment among youth.

Bullock A, Liu J, Cheah CSL, Coplan RJ, Chen X, Li D.

J Adolesc. 2018 Oct;68:117-126. doi: 10.1016/j.adolescence.2018.07.007. Epub 2018 Jul 31.


Hepatic and renal end-organ damage in the Fontan circulation: A report from the Australian and New Zealand Fontan Registry.

Wilson TG, d'Udekem Y, Winlaw DS, Cordina RL, Celermajer DS, Wheaton GR, Bullock A, Gentles TL, Weintraub RG, Justo RN, Grigg LE, Radford DJ, Hardikar W, Cheung M, Cain TM, Rao P, Alexander SI, Ayer J, Verrall C, Du Plessis K, Chapman J, Rice K, Barry J, Zannino D, Iyengar AJ; Australian and New Zealand Fontan Registry.

Int J Cardiol. 2018 Dec 15;273:100-107. doi: 10.1016/j.ijcard.2018.07.118. Epub 2018 Jul 25.


Clinical skills of a new foundation dentist: the experience of dental foundation educational supervisors.

Jones RJ, Cowpe JG, Bullock AD, Gilmour ASM.

Br Dent J. 2018 Jul 27;225(2):177-186. doi: 10.1038/sj.bdj.2018.536. No abstract available.


Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling.

Hrdinka M, Schlicher L, Dai B, Pinkas DM, Bufton JC, Picaud S, Ward JA, Rogers C, Suebsuwong C, Nikhar S, Cuny GD, Huber KV, Filippakopoulos P, Bullock AN, Degterev A, Gyrd-Hansen M.

EMBO J. 2018 Sep 3;37(17). pii: e99372. doi: 10.15252/embj.201899372. Epub 2018 Jul 19.


General dental practices with and without a dental therapist: a survey of appointment activities and patient satisfaction with their care.

Barnes E, Bullock A, Cowpe J, Moons K, Warren W, Hannington D, Allen M, Chestnutt IG, Bale S, Negrotti C.

Br Dent J. 2018 Jul 13;225(1):53-58. doi: 10.1038/sj.bdj.2018.522. No abstract available.


Visualisation of the insertion of a membrane for the treatment of preterm rupture of fetal membranes using a synthetic model of a pregnant uterus.

Roman S, Hillary C, Narice B, Bullock AJ, Anumba DO, MacNeil S.

J Biomater Appl. 2018 Aug;33(2):234-244. doi: 10.1177/0885328218786038. Epub 2018 Jul 12.


Recruitment and effectiveness by cohort in a case management intervention among American Indians and Alaska Natives with diabetes.

Pratte KA, Beals J, Johnson A, Bullock A, Manson SM, Jiang L; Special Diabetes Program for Indians Healthy Heart Project Demonstration Project.

Transl Behav Med. 2018 Jul 3. doi: 10.1093/tbm/iby068. [Epub ahead of print]


Clinical skills of a new foundation dentist: the expectations of dental foundation education supervisors.

Gilmour ASM, Jones RJ, Cowpe JG, Bullock AD.

Br Dent J. 2018 Jul 13;225(1):73-80. doi: 10.1038/sj.bdj.2018.526. Epub 2018 Jul 6. No abstract available.


What Patients Look for When Browsing Online for Pancreatic Cancer: The Bait Behind the Byte.

Storino A, Guetter C, Castillo-Angeles M, Watkins AA, Mancias JD, Bullock A, James Moser A, Kent TS.

World J Surg. 2018 Dec;42(12):4097-4106. doi: 10.1007/s00268-018-4719-2.


Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer.

Yurgelun MB, Chittenden AB, Morales-Oyarvide V, Rubinson DA, Dunne RF, Kozak MM, Qian ZR, Welch MW, Brais LK, Da Silva A, Bui JL, Yuan C, Li T, Li W, Masuda A, Gu M, Bullock AJ, Chang DT, Clancy TE, Linehan DC, Findeis-Hosey JJ, Doyle LA, Thorner AR, Ducar MD, Wollison BM, Khalaf N, Perez K, Syngal S, Aguirre AJ, Hahn WC, Meyerson ML, Fuchs CS, Ogino S, Hornick JL, Hezel AF, Koong AC, Nowak JA, Wolpin BM.

Genet Med. 2019 Jan;21(1):213-223. doi: 10.1038/s41436-018-0009-5. Epub 2018 Jul 2.


Long-term Outcomes of Lifestyle Intervention to Prevent Diabetes in American Indian and Alaska Native Communities: The Special Diabetes Program for Indians Diabetes Prevention Program.

Jiang L, Johnson A, Pratte K, Beals J, Bullock A, Manson SM; Special Diabetes Program for Indians Diabetes Prevention Program.

Diabetes Care. 2018 Jul;41(7):1462-1470. doi: 10.2337/dc17-2685.

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