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Items: 1 to 50 of 64

1.

Stepwise approach towards adoption of allergen immunotherapy for allergic rhinitis and asthma patients in daily practice in Belgium: a BelSACI-Abeforcal-EUFOREA statement.

Hellings PW, Pugin B, Mariën G, Bachert C, Breynaert C, Bullens DM, Ceuppens JL, Clement G, Cox T, Ebo D, Gevaert P, Halewyck S, Hox V, Ladha K, Jacobs R, Rombaux P, Schrijvers R, Speleman K, Van der Brempt X, Van Gerven L, Vanderveken O, Verhaeghe B, Vierstraete K, Vlaminck S, Watelet JB, Bousquet J, Seys SF.

Clin Transl Allergy. 2019 Feb 4;9:1. doi: 10.1186/s13601-019-0243-1. eCollection 2019. Review.

2.

Innate lymphoid cells in asthma: pathophysiological insights from murine models to human asthma phenotypes.

Jonckheere AC, Bullens DMA, Seys SF.

Curr Opin Allergy Clin Immunol. 2019 Feb;19(1):53-60. doi: 10.1097/ACI.0000000000000497.

PMID:
30516548
3.

New insights in neutrophilic asthma.

Seys SF, Lokwani R, Simpson JL, Bullens DMA.

Curr Opin Pulm Med. 2019 Jan;25(1):113-120. doi: 10.1097/MCP.0000000000000543.

PMID:
30422895
4.

AQUA© Questionnaire as prediction tool for atopy in young elite athletes.

Jonckheere AC, Seys SF, Dilissen E, Marijsse G, Schelpe AS, Van der Eycken S, Verhalle T, Vanbelle V, Aertgeerts S, Troosters T, Peers K, Dupont LJ, Bullens DMA.

Pediatr Allergy Immunol. 2018 Sep;29(6):648-650. doi: 10.1111/pai.12949. Epub 2018 Jul 9. No abstract available.

PMID:
29908073
5.

Exercise and Sinonasal Disease.

Steelant B, Hox V, Hellings PW, Bullens DM, Seys SF.

Immunol Allergy Clin North Am. 2018 May;38(2):259-269. doi: 10.1016/j.iac.2018.01.014. Epub 2018 Mar 2. Review.

PMID:
29631734
6.

Nasal symptoms, epithelial injury and neurogenic inflammation in elite swimmers.

Steelant B, Hox V, Van Gerven L, Dilissen E, Dekimpe E, Kasran A, Aertgeerts S, Van Belle V, Peers K, Dupont LJ, Hellings PW, Bullens DM, Seys SF.

Rhinology. 2018 Sep 1;56(3):279-287. doi: 10.4193/Rhin17.167.

PMID:
29561921
7.

Point-of-care C reactive protein to identify serious infection in acutely ill children presenting to hospital: prospective cohort study.

Verbakel JY, Lemiengre MB, De Burghgraeve T, De Sutter A, Aertgeerts B, Bullens DMA, Shinkins B, Van den Bruel A, Buntinx F.

Arch Dis Child. 2018 May;103(5):420-426. doi: 10.1136/archdischild-2016-312384. Epub 2017 Dec 21.

PMID:
29269559
8.

Histamine and T helper cytokine-driven epithelial barrier dysfunction in allergic rhinitis.

Steelant B, Seys SF, Van Gerven L, Van Woensel M, Farré R, Wawrzyniak P, Kortekaas Krohn I, Bullens DM, Talavera K, Raap U, Boon L, Akdis CA, Boeckxstaens G, Ceuppens JL, Hellings PW.

J Allergy Clin Immunol. 2018 Mar;141(3):951-963.e8. doi: 10.1016/j.jaci.2017.08.039. Epub 2017 Oct 23.

9.

Immunotherapy with subcutaneous immunogenic autologous tumor lysate increases murine glioblastoma survival.

Belmans J, Van Woensel M, Creyns B, Dejaegher J, Bullens DM, Van Gool SW.

Sci Rep. 2017 Oct 24;7(1):13902. doi: 10.1038/s41598-017-12584-0.

10.

Mechanisms of exercise-induced bronchoconstriction in athletes: Current perspectives and future challenges.

Couto M, Kurowski M, Moreira A, Bullens DMA, Carlsen KH, Delgado L, Kowalski ML, Seys SF.

Allergy. 2018 Jan;73(1):8-16. doi: 10.1111/all.13224. Epub 2017 Jul 12. Review.

PMID:
28599081
11.

Cluster analysis of sputum cytokine-high profiles reveals diversity in T(h)2-high asthma patients.

Seys SF, Scheers H, Van den Brande P, Marijsse G, Dilissen E, Van Den Bergh A, Goeminne PC, Hellings PW, Ceuppens JL, Dupont LJ, Bullens DM.

Respir Res. 2017 Feb 23;18(1):39. doi: 10.1186/s12931-017-0524-y.

12.

Programmed cell death-1 expression correlates with disease severity and IL-5 in chronic rhinosinusitis with nasal polyps.

Kortekaas Krohn I, Bobic S, Dooley J, Lan F, Zhang N, Bachert C, Steelant B, Bullens DM, Liston A, Ceuppens JL, Seys SF, Hellings PW.

Allergy. 2017 Jun;72(6):985-993. doi: 10.1111/all.13136. Epub 2017 Mar 6.

PMID:
28122135
13.

Clinical-Grade Human Multipotent Adult Progenitor Cells Block CD8+ Cytotoxic T Lymphocytes.

Plessers J, Dekimpe E, Van Woensel M, Roobrouck VD, Bullens DM, Pinxteren J, Verfaillie CM, Van Gool SW.

Stem Cells Transl Med. 2016 Dec;5(12):1607-1619. Epub 2016 Jul 27.

14.

Impaired barrier function in patients with house dust mite-induced allergic rhinitis is accompanied by decreased occludin and zonula occludens-1 expression.

Steelant B, Farré R, Wawrzyniak P, Belmans J, Dekimpe E, Vanheel H, Van Gerven L, Kortekaas Krohn I, Bullens DMA, Ceuppens JL, Akdis CA, Boeckxstaens G, Seys SF, Hellings PW.

J Allergy Clin Immunol. 2016 Apr;137(4):1043-1053.e5. doi: 10.1016/j.jaci.2015.10.050. Epub 2016 Feb 2.

15.

Feasibility to apply eucapnic voluntary hyperventilation in young elite athletes.

Van der Eycken S, Schelpe A, Marijsse G, Dilissen E, Troosters T, Vanbelle V, Aertgeerts S, Dupont LJ, Peers K, Bullens DM, Seys SF.

Respir Med. 2016 Feb;111:91-3. doi: 10.1016/j.rmed.2015.12.012. Epub 2016 Jan 4.

16.

Validating a decision tree for serious infection: diagnostic accuracy in acutely ill children in ambulatory care.

Verbakel JY, Lemiengre MB, De Burghgraeve T, De Sutter A, Aertgeerts B, Bullens DM, Shinkins B, Van den Bruel A, Buntinx F.

BMJ Open. 2015 Aug 7;5(8):e008657. doi: 10.1136/bmjopen-2015-008657.

17.

Piliation of Lactobacillus rhamnosus GG promotes adhesion, phagocytosis, and cytokine modulation in macrophages.

Vargas García CE, Petrova M, Claes IJ, De Boeck I, Verhoeven TL, Dilissen E, von Ossowski I, Palva A, Bullens DM, Vanderleyden J, Lebeer S.

Appl Environ Microbiol. 2015 Mar;81(6):2050-62. doi: 10.1128/AEM.03949-14. Epub 2015 Jan 9.

18.

Damage-associated molecular pattern and innate cytokine release in the airways of competitive swimmers.

Seys SF, Hox V, Van Gerven L, Dilissen E, Marijsse G, Peeters E, Dekimpe E, Kasran A, Aertgeerts S, Troosters T, Vanbelle V, Peers K, Ceuppens JL, Hellings PW, Dupont LJ, Bullens DM.

Allergy. 2015 Feb;70(2):187-94. doi: 10.1111/all.12540.

PMID:
25358760
19.

Diagnosing serious infections in acutely ill children in ambulatory care (ERNIE 2 study protocol, part A): diagnostic accuracy of a clinical decision tree and added value of a point-of-care C-reactive protein test and oxygen saturation.

Verbakel JY, Lemiengre MB, De Burghgraeve T, De Sutter A, Bullens DM, Aertgeerts B, Buntinx F; ERNIE 2 collaboration.

BMC Pediatr. 2014 Oct 2;14:207. doi: 10.1186/1471-2431-14-207.

20.

Low cord blood Foxp3/CD3γ mRNA ratios: a marker of increased risk for allergy development.

Bullens DM, Seys S, Kasran A, Dilissen E, Dupont LJ, Ceuppens JL.

Clin Exp Allergy. 2015 Jan;45(1):232-7. doi: 10.1111/cea.12389.

PMID:
25113399
21.

Obese individuals with asthma preferentially have a high IL-5/IL-17A/IL-25 sputum inflammatory pattern.

Marijsse GS, Seys SF, Schelpe AS, Dilissen E, Goeminne P, Dupont LJ, Ceuppens JL, Bullens DM.

Am J Respir Crit Care Med. 2014 May 15;189(10):1284-5. doi: 10.1164/rccm.201311-2011LE. No abstract available.

PMID:
24832749
22.

Analytical accuracy and user-friendliness of the Afinion point-of-care CRP test.

Verbakel JY, Aertgeerts B, Lemiengre M, Sutter AD, Bullens DM, Buntinx F.

J Clin Pathol. 2014 Jan;67(1):83-6. doi: 10.1136/jclinpath-2013-201654. Epub 2013 Sep 11. No abstract available.

PMID:
24025452
23.

Sputum cytokine mapping reveals an 'IL-5, IL-17A, IL-25-high' pattern associated with poorly controlled asthma.

Seys SF, Grabowski M, Adriaensen W, Decraene A, Dilissen E, Vanoirbeek JA, Dupont LJ, Ceuppens JL, Bullens DM.

Clin Exp Allergy. 2013 Sep;43(9):1009-17. doi: 10.1111/cea.12125.

PMID:
23957336
24.

Effect of nasal anti-inflammatory treatment in chronic obstructive pulmonary disease.

Callebaut I, Hox V, Bobic S, Bullens DM, Janssens W, Dupont L, Hellings PW.

Am J Rhinol Allergy. 2013 Jul-Aug;27(4):273-7. doi: 10.2500/ajra.2013.27.3887.

PMID:
23883807
25.

Effects of high altitude and cold air exposure on airway inflammation in patients with asthma.

Seys SF, Daenen M, Dilissen E, Van Thienen R, Bullens DM, Hespel P, Dupont LJ.

Thorax. 2013 Oct;68(10):906-13. doi: 10.1136/thoraxjnl-2013-203280. Epub 2013 Jul 2.

PMID:
23821393
26.

IL-17A in human respiratory diseases: innate or adaptive immunity? Clinical implications.

Bullens DM, Decraene A, Seys S, Dupont LJ.

Clin Dev Immunol. 2013;2013:840315. doi: 10.1155/2013/840315. Epub 2013 Jan 17. Review.

27.

Crucial role of transient receptor potential ankyrin 1 and mast cells in induction of nonallergic airway hyperreactivity in mice.

Hox V, Vanoirbeek JA, Alpizar YA, Voedisch S, Callebaut I, Bobic S, Sharify A, De Vooght V, Van Gerven L, Devos F, Liston A, Voets T, Vennekens R, Bullens DM, De Vries A, Hoet P, Braun A, Ceuppens JL, Talavera K, Nemery B, Hellings PW.

Am J Respir Crit Care Med. 2013 Mar 1;187(5):486-93. doi: 10.1164/rccm.201208-1358OC. Epub 2012 Dec 21.

PMID:
23262517
28.

Airway inflammation in patients with chronic non-asthmatic cough.

Grabowski M, Seys S, Decraene A, Kasran A, Dilissen E, Barg W, Medrala W, Dupont LJ, Panaszek B, Bullens DM.

Thorax. 2013 Feb;68(2):125-30. doi: 10.1136/thoraxjnl-2012-201895. Epub 2012 Oct 23.

PMID:
23093651
29.

Neonatal IL-10 production and risk of allergy development.

Bullens DM, Kasran A, Dilissen E, Ceuppens JL.

Clin Exp Allergy. 2012 Mar;42(3):483-4; author reply 485. doi: 10.1111/j.1365-2222.2011.03952.x. No abstract available.

PMID:
22356147
30.

Placental growth factor contributes to bronchial neutrophilic inflammation and edema in allergic asthma.

Bobic S, Seys S, De Vooght V, Callebaut I, Hox V, Dooms C, Vinckier S, Jonckx B, Saint-Remy JM, Stassen JM, Bullens DM, Ceuppens JL, Carmeliet P, Hellings PW.

Am J Respir Cell Mol Biol. 2012 Jun;46(6):781-9. doi: 10.1165/rcmb.2011-0152OC. Epub 2012 Jan 20.

PMID:
22268141
31.

In vivo maturation of T(H) cells in relation to atopy.

Bullens DM, Kasran A, Dilissen E, De Swert K, Coorevits L, Van Snick J, Ceuppens JL.

J Allergy Clin Immunol. 2011 Jul;128(1):234-237.e7. doi: 10.1016/j.jaci.2011.02.033. Epub 2011 Mar 24. No abstract available.

PMID:
21439621
32.

Elevated expression of both mRNA and protein levels of IL-17A in sputum of stable Cystic Fibrosis patients.

Decraene A, Willems-Widyastuti A, Kasran A, De Boeck K, Bullens DM, Dupont LJ.

Respir Res. 2010 Dec 10;11:177. doi: 10.1186/1465-9921-11-177.

33.

Impact of lipoteichoic acid modification on the performance of the probiotic Lactobacillus rhamnosus GG in experimental colitis.

Claes IJ, Lebeer S, Shen C, Verhoeven TL, Dilissen E, De Hertogh G, Bullens DM, Ceuppens JL, Van Assche G, Vermeire S, Rutgeerts P, Vanderleyden J, De Keersmaecker SC.

Clin Exp Immunol. 2010 Nov;162(2):306-14. doi: 10.1111/j.1365-2249.2010.04228.x. Epub 2010 Aug 20.

34.

Monitoring the effect of allergen immunotherapy: a clinician's dream comes true?

Bullens DM.

Clin Exp Allergy. 2010 Jul;40(7):958-61. doi: 10.1111/j.1365-2222.2010.03526.x. No abstract available.

PMID:
20642573
35.

Murine bone marrow chimeras developing autoimmunity after CTLA-4-blockade show an expansion of T regulatory cells with an activated cytokine profile.

De Somer L, Fevery S, Bullens DM, Rutgeerts O, Lenaerts C, Mathieu C, Boon L, Kasran A, Waer M, Billiau AD.

Immunol Lett. 2010 Sep 6;133(1):49-53. doi: 10.1016/j.imlet.2010.06.005. Epub 2010 Jun 18.

PMID:
20600326
36.

Selective nasal allergen provocation induces substance P-mediated bronchial hyperresponsiveness.

Hens G, Raap U, Vanoirbeek J, Meyts I, Callebaut I, Verbinnen B, Vanaudenaerde BM, Cadot P, Nemery B, Bullens DM, Ceuppens JL, Hellings PW.

Am J Respir Cell Mol Biol. 2011 Apr;44(4):517-23. doi: 10.1165/rcmb.2009-0425OC. Epub 2010 Jun 10.

PMID:
20539012
37.

Staphylococcus aureus enterotoxin B facilitates allergic sensitization in experimental asthma.

Huvenne W, Callebaut I, Plantinga M, Vanoirbeek JA, Krysko O, Bullens DM, Gevaert P, Van Cauwenberge P, Lambrecht BN, Ceuppens JL, Bachert C, Hellings PW.

Clin Exp Allergy. 2010 Jul;40(7):1079-90. doi: 10.1111/j.1365-2222.2010.03464.x. Epub 2010 Mar 1.

PMID:
20214664
38.

Sensitization to inhaled ryegrass pollen by collateral priming in a murine model of allergic respiratory disease.

Cadot P, Meyts I, Vanoirbeek JA, Vanaudenaerde B, Bullens DM, Ceuppens JL.

Int Arch Allergy Immunol. 2010;152(3):233-42. doi: 10.1159/000283031. Epub 2010 Feb 11.

PMID:
20150741
39.

Staphylococcus aureus enterotoxin B augments granulocyte migration and survival via airway epithelial cell activation.

Huvenne W, Callebaut I, Reekmans K, Hens G, Bobic S, Jorissen M, Bullens DM, Ceuppens JL, Bachert C, Hellings PW.

Allergy. 2010 Aug;65(8):1013-20. doi: 10.1111/j.1398-9995.2009.02313.x. Epub 2010 Feb 4.

PMID:
20132156
40.

Searching for regulatory T cells in allergy: are we nearing the 'Finish'?

Bullens DM.

Clin Exp Allergy. 2008 Nov;38(11):1707-8. doi: 10.1111/j.1365-2222.2008.03105.x. No abstract available.

PMID:
19489914
41.
42.

The role of the IL23/IL17 axis in bronchiolitis obliterans syndrome after lung transplantation.

Vanaudenaerde BM, De Vleeschauwer SI, Vos R, Meyts I, Bullens DM, Reynders V, Wuyts WA, Van Raemdonck DE, Dupont LJ, Verleden GM.

Am J Transplant. 2008 Sep;8(9):1911-20. doi: 10.1111/j.1600-6143.2008.02321.x.

43.

Contribution of regulatory T cells and effector T cell deletion in tolerance induction by costimulation blockade.

Verbinnen B, Billiau AD, Vermeiren J, Galicia G, Bullens DM, Boon L, Cadot P, Hens G, Dewolf-Peeters C, Van Gool SW, Ceuppens JL.

J Immunol. 2008 Jul 15;181(2):1034-42.

44.

Type III IFN-lambda mRNA expression in sputum of adult and school-aged asthmatics.

Bullens DM, Decraene A, Dilissen E, Meyts I, De Boeck K, Dupont LJ, Ceuppens JL.

Clin Exp Allergy. 2008 Sep;38(9):1459-67. doi: 10.1111/j.1365-2222.2008.03045.x. Epub 2008 Jun 28.

PMID:
18564328
45.

T-cell mediated late increase in bronchial tone after allergen provocation in a murine asthma model.

Meyts I, Vanoirbeek JA, Hens G, Vanaudenaerde BM, Verbinnen B, Bullens DM, Overbergh L, Mathieu C, Ceuppens JL, Hellings PW.

Clin Immunol. 2008 Aug;128(2):248-58. doi: 10.1016/j.clim.2008.03.515. Epub 2008 May 27.

PMID:
18502692
46.

Sinonasal pathology in nonallergic asthma and COPD: 'united airway disease' beyond the scope of allergy.

Hens G, Vanaudenaerde BM, Bullens DM, Piessens M, Decramer M, Dupont LJ, Ceuppens JL, Hellings PW.

Allergy. 2008 Mar;63(3):261-7. Epub 2007 Dec 5.

PMID:
18053011
47.

Measuring T cell cytokines in allergic upper and lower airway inflammation: can we move to the clinic?

Bullens DM.

Inflamm Allergy Drug Targets. 2007 Jun;6(2):81-90. Review.

PMID:
17692031
48.

Rapidly induced, T-cell independent xenoantibody production is mediated by marginal zone B cells and requires help from NK cells.

Li S, Yan Y, Lin Y, Bullens DM, Rutgeerts O, Goebels J, Segers C, Boon L, Kasran A, De Vos R, Dewolf-Peeters C, Waer M, Billiau AD.

Blood. 2007 Dec 1;110(12):3926-35. Epub 2007 Jul 13.

49.

Remission-inducing effect of anti-TNF monoclonal antibody in TNBS colitis: mechanisms beyond neutralization?

Shen C, de Hertogh G, Bullens DM, Van Assche G, Geboes K, Rutgeerts P, Ceuppens JL.

Inflamm Bowel Dis. 2007 Mar;13(3):308-16.

PMID:
17206708
50.

IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?

Bullens DM, Truyen E, Coteur L, Dilissen E, Hellings PW, Dupont LJ, Ceuppens JL.

Respir Res. 2006 Nov 3;7:135.

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