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Items: 1 to 50 of 161

1.

Listeria monocytogenes hijacks CD147 to ensure proper membrane protrusion formation and efficient bacterial dissemination.

Dhanda AS, Lulic KT, Yu C, Chiu RH, Bukrinsky M, Guttman JA.

Cell Mol Life Sci. 2019 May 10. doi: 10.1007/s00018-019-03130-4. [Epub ahead of print]

PMID:
31076805
2.

HIV disease, metabolic dysfunction and atherosclerosis: A three year prospective study.

Low H, Hoang A, Pushkarsky T, Dubrovsky L, Dewar E, Di Yacovo MS, Mukhamedova N, Cheng L, Downs C, Simon G, Saumoy M, Hill AF, Fitzgerald ML, Nestel P, Dart A, Hoy J, Bukrinsky M, Sviridov D.

PLoS One. 2019 Apr 18;14(4):e0215620. doi: 10.1371/journal.pone.0215620. eCollection 2019.

3.

Modified LDL Particles Activate Inflammatory Pathways in Monocyte-derived Macrophages: Transcriptome Analysis.

Orekhov AN, Oishi Y, Nikiforov NG, Zhelankin AV, Dubrovsky L, Sobenin IA, Kel A, Stelmashenko D, Makeev VJ, Foxx K, Jin X, Kruth HS, Bukrinsky M.

Curr Pharm Des. 2018;24(26):3143-3151. doi: 10.2174/1381612824666180911120039.

4.

HDL activates expression of genes stimulating cholesterol efflux in human monocyte-derived macrophages.

Orekhov AN, Pushkarsky T, Oishi Y, Nikiforov NG, Zhelankin AV, Dubrovsky L, Makeev VJ, Foxx K, Jin X, Kruth HS, Sobenin IA, Sukhorukov VN, Zakiev ER, Kontush A, Le Goff W, Bukrinsky M.

Exp Mol Pathol. 2018 Oct;105(2):202-207. doi: 10.1016/j.yexmp.2018.08.003. Epub 2018 Aug 16.

PMID:
30118702
5.

Modelling interaction between HIV-1 Nef and calnexin.

Adzhubei AA, Anashkina AA, Tkachev YV, Kravatsky YV, Pushkarsky T, Kulkarni A, Makarov AA, Bukrinsky MI.

AIDS. 2018 Sep 24;32(15):2103-2111. doi: 10.1097/QAD.0000000000001951.

PMID:
30005006
6.

Atherosclerosis in subjects newly diagnosed with human immunodeficiency virus infection.

Kirichenko TV, Myasoedova VA, Shimonova TE, Melnichenko AA, Sviridov D, Sobenin IA, Mazus AI, Orekhov AN, Bukrinsky MI.

Biosci Rep. 2018 Jul 18;38(4). pii: BSR20180597. doi: 10.1042/BSR20180597. Print 2018 Aug 31.

7.

Association of a 3' untranslated region polymorphism in proprotein convertase subtilisin/kexin type 9 with HIV viral load and CD4+ levels in HIV/hepatitis C virus coinfected women.

Kuniholm MH, Liang H, Anastos K, Gustafson D, Kassaye S, Nowicki M, Sha BE, Pawlowski EJ, Gange SJ, Aouizerat BE, Pushkarsky T, Bukrinsky MI, Prasad VR.

AIDS. 2017 Nov 28;31(18):2483-2492. doi: 10.1097/QAD.0000000000001648.

8.

Yeast help identify cytopathic factors of Zika virus.

Bukrinsky M.

Cell Biosci. 2017 Feb 20;7:12. doi: 10.1186/s13578-017-0139-5. eCollection 2017.

9.

Use of Primary Macrophages for Searching Novel Immunocorrectors.

Nikiforov NG, Elizova NV, Bukrinsky M, Dubrovsky L, Makeev VJ, Wakabayashi Y, Liu P, Foxx KK, Kruth HS, Jin X, Zakiev ER, Orekhov AN.

Curr Pharm Des. 2017;23(6):915-920. doi: 10.2174/1381612823666170125110128. Review.

10.

Cold Atmospheric Plasma Inhibits HIV-1 Replication in Macrophages by Targeting Both the Virus and the Cells.

Volotskova O, Dubrovsky L, Keidar M, Bukrinsky M.

PLoS One. 2016 Oct 26;11(10):e0165322. doi: 10.1371/journal.pone.0165322. eCollection 2016.

11.

HIV-1 Integrates Widely throughout the Genome of the Human Blood Fluke Schistosoma mansoni.

Suttiprapa S, Rinaldi G, Tsai IJ, Mann VH, Dubrovsky L, Yan HB, Holroyd N, Huckvale T, Durrant C, Protasio AV, Pushkarsky T, Iordanskiy S, Berriman M, Bukrinsky MI, Brindley PJ.

PLoS Pathog. 2016 Oct 20;12(10):e1005931. doi: 10.1371/journal.ppat.1005931. eCollection 2016 Oct.

12.

Small GTPase ARF6 Regulates Endocytic Pathway Leading to Degradation of ATP-Binding Cassette Transporter A1.

Mukhamedova N, Hoang A, Cui HL, Carmichael I, Fu Y, Bukrinsky M, Sviridov D.

Arterioscler Thromb Vasc Biol. 2016 Dec;36(12):2292-2303. Epub 2016 Oct 6.

13.

Short Communication: Accumulation of Neutral Lipids in Liver and Aorta of Nef-Transgenic Mice.

Pushkarsky T, Shilov E, Kruglova N, Naumann R, Brichacek B, Jennelle L, Sviridov D, Kruglov A, Nedospasov SA, Bukrinsky M.

AIDS Res Hum Retroviruses. 2017 Jan;33(1):57-60. doi: 10.1089/AID.2016.0128. Epub 2016 Oct 25.

14.

Interaction Between HIV-1 Nef and Calnexin: From Modeling to Small Molecule Inhibitors Reversing HIV-Induced Lipid Accumulation.

Hunegnaw R, Vassylyeva M, Dubrovsky L, Pushkarsky T, Sviridov D, Anashkina AA, √úren A, Brichacek B, Vassylyev DG, Adzhubei AA, Bukrinsky M.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1758-71. doi: 10.1161/ATVBAHA.116.307997. Epub 2016 Jul 28.

15.

Cellular minichromosome maintenance complex component 5 (MCM5) is incorporated into HIV-1 virions and modulates viral replication in the newly infected cells.

Santos S, Obukhov Y, Nekhai S, Pushkarsky T, Brichacek B, Bukrinsky M, Iordanskiy S.

Virology. 2016 Oct;497:11-22. doi: 10.1016/j.virol.2016.06.023. Epub 2016 Jul 12.

16.

Cytomegalovirus Restructures Lipid Rafts via a US28/CDC42-Mediated Pathway, Enhancing Cholesterol Efflux from Host Cells.

Low H, Mukhamedova N, Cui HL, McSharry BP, Avdic S, Hoang A, Ditiatkovski M, Liu Y, Fu Y, Meikle PJ, Blomberg M, Polyzos KA, Miller WE, Religa P, Bukrinsky M, Soderberg-Naucler C, Slobedman B, Sviridov D.

Cell Rep. 2016 Jun 28;16(1):186-200. doi: 10.1016/j.celrep.2016.05.070. Epub 2016 Jun 16.

17.

Live Cell Imaging of ABCA1 Downregulation by HIV-1 Nef in an Experimental Model of HeLa ABCA1-GFP.

Siegel J, Darwish C, Popratiloff A, Bukrinsky M, Brichacek B.

AIDS Res Hum Retroviruses. 2016 Sep;32(9):872-3. doi: 10.1089/aid.2015.0362. Epub 2016 May 2. No abstract available.

18.

Mechanisms of HIV Transcriptional Regulation by Drugs of Abuse.

Tyagi M, Bukrinsky M, Simon GL.

Curr HIV Res. 2016;14(5):442-454. Review.

19.

Lipidomic dataset of plasma from patients infected with wild type and nef-deficient HIV-1 strain.

Meikle P, Low H, Churchill MJ, Bukrinsky M, Sviridov D.

Data Brief. 2015 Dec 11;6:168-75. doi: 10.1016/j.dib.2015.11.067. eCollection 2016 Mar.

20.

Analysis of ABCA1 and Cholesterol Efflux in HIV-Infected Cells.

Mukhamedova N, Brichacek B, Darwish C, Popratiloff A, Sviridov D, Bukrinsky M.

Methods Mol Biol. 2016;1354:281-92. doi: 10.1007/978-1-4939-3046-3_19.

21.

Lipid metabolism in patients infected with Nef-deficient HIV-1 strain.

Low H, Cheng L, Di Yacovo MS, Churchill MJ, Meikle P, Bukrinsky M, Hill AF, Sviridov D.

Atherosclerosis. 2016 Jan;244:22-8. doi: 10.1016/j.atherosclerosis.2015.10.103. Epub 2015 Oct 30.

22.

The effects of cocaine on HIV transcription.

Tyagi M, Weber J, Bukrinsky M, Simon GL.

J Neurovirol. 2016 Jun;22(3):261-74. doi: 10.1007/s13365-015-0398-z. Epub 2015 Nov 16. Review.

23.

Jan van der Noordaa (1934-2015); A Virologist Pur Sang.

Berkhout B, Bukrinsky M.

Viruses. 2015 Sep 15;7(9):5016-7. doi: 10.3390/v7092859.

24.

HIV infection induces structural and functional changes in high density lipoproteins.

Siegel MO, Borkowska AG, Dubrovsky L, Roth M, Welti R, Roberts AD, Parenti DM, Simon GL, Sviridov D, Simmens S, Bukrinsky M, Fitzgerald ML.

Atherosclerosis. 2015 Nov;243(1):19-29. doi: 10.1016/j.atherosclerosis.2015.08.036. Epub 2015 Aug 29.

25.

Targeting Extracellular Cyclophilins Ameliorates Disease Progression in Experimental Biliary Atresia.

Iordanskaia T, Malesevic M, Fischer G, Pushkarsky T, Bukrinsky M, Nadler EP.

Mol Med. 2015 Oct;21(1):657-664. doi: 10.2119/molmed.2015.00076. Epub 2015 Jul 24.

26.

Stimulation of Liver X Receptor Has Potent Anti-HIV Effects in a Humanized Mouse Model of HIV Infection.

Ramezani A, Dubrovsky L, Pushkarsky T, Sviridov D, Karandish S, Raj DS, Fitzgerald ML, Bukrinsky M.

J Pharmacol Exp Ther. 2015 Sep;354(3):376-83. doi: 10.1124/jpet.115.224485. Epub 2015 Jun 30.

27.

Inhibition of extracellular cyclophilins with cyclosporine analog and development of atherosclerosis in apolipoprotein E-deficient mice.

Ditiatkovski M, Neelisetti VN, Cui HL, Malesevic M, Fischer G, Bukrinsky M, Sviridov D.

J Pharmacol Exp Ther. 2015 Jun;353(3):490-5. doi: 10.1124/jpet.115.223420. Epub 2015 Mar 18.

PMID:
25788712
28.

Extracellular cyclophilins in health and disease.

Bukrinsky M.

Biochim Biophys Acta. 2015 Oct;1850(10):2087-95. doi: 10.1016/j.bbagen.2014.11.013. Epub 2014 Nov 18. Review.

29.

HIV-1 infection of macrophages induces retention of cholesterol transporter ABCA1 in the endoplasmic reticulum.

Brichacek B, Darwish C, Popratiloff A, Dubrovsky L, Bukrinsky M.

AIDS Res Hum Retroviruses. 2014 Oct;30(10):947-8. doi: 10.1089/aid.2014.0156. Epub 2014 Sep 8. No abstract available.

30.

HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexin.

Jennelle L, Hunegnaw R, Dubrovsky L, Pushkarsky T, Fitzgerald ML, Sviridov D, Popratiloff A, Brichacek B, Bukrinsky M.

J Biol Chem. 2014 Oct 17;289(42):28870-84. doi: 10.1074/jbc.M114.583591. Epub 2014 Aug 28.

31.

Interaction of pathogens with host cholesterol metabolism.

Sviridov D, Bukrinsky M.

Curr Opin Lipidol. 2014 Oct;25(5):333-8. doi: 10.1097/MOL.0000000000000106. Review.

32.

New clues to understanding HIV nonprogressors: low cholesterol blocks HIV trans infection.

Prasad VR, Bukrinsky MI.

MBio. 2014 Jun 10;5(3):e01396-14. doi: 10.1128/mBio.01396-14.

33.

HIV protein Nef causes dyslipidemia and formation of foam cells in mouse models of atherosclerosis.

Cui HL, Ditiatkovski M, Kesani R, Bobryshev YV, Liu Y, Geyer M, Mukhamedova N, Bukrinsky M, Sviridov D.

FASEB J. 2014 Jul;28(7):2828-39. doi: 10.1096/fj.13-246876. Epub 2014 Mar 18.

34.

The ABCA1 domain responsible for interaction with HIV-1 Nef is conformational and not linear.

Jacob D, Hunegnaw R, Sabyrzyanova TA, Pushkarsky T, Chekhov VO, Adzhubei AA, Kalebina TS, Bukrinsky M.

Biochem Biophys Res Commun. 2014 Jan 31;444(1):19-23. doi: 10.1016/j.bbrc.2013.12.141. Epub 2014 Jan 7.

35.

Prion infection impairs cholesterol metabolism in neuronal cells.

Cui HL, Guo B, Scicluna B, Coleman BM, Lawson VA, Ellett L, Meikle PJ, Bukrinsky M, Mukhamedova N, Sviridov D, Hill AF.

J Biol Chem. 2014 Jan 10;289(2):789-802. doi: 10.1074/jbc.M113.535807. Epub 2013 Nov 26.

36.

HIV-1 accessory proteins: VpR.

Zhao RY, Bukrinsky MI.

Methods Mol Biol. 2014;1087:125-34. doi: 10.1007/978-1-62703-670-2_11.

37.

Nature, nurture and HIV: The effect of producer cell on viral physiology.

Iordanskiy S, Santos S, Bukrinsky M.

Virology. 2013 Sep 1;443(2):208-13. doi: 10.1016/j.virol.2013.05.023. Epub 2013 Jun 5. Review.

38.

The effect of HIV infection on atherosclerosis and lipoprotein metabolism: a one year prospective study.

Rose H, Low H, Dewar E, Bukrinsky M, Hoy J, Dart A, Sviridov D.

Atherosclerosis. 2013 Jul;229(1):206-11. doi: 10.1016/j.atherosclerosis.2013.04.010. Epub 2013 Apr 17.

39.

Cyclophilins in atherosclerosis: a new therapeutic target?

Bukrinsky M, Orekhov A, Ditiatkovski M, Sviridov D.

Curr Pharm Des. 2013;19(33):5904-8. Review.

PMID:
23438962
40.

Virus-producing cells determine the host protein profiles of HIV-1 virion cores.

Santos S, Obukhov Y, Nekhai S, Bukrinsky M, Iordanskiy S.

Retrovirology. 2012 Aug 13;9:65. doi: 10.1186/1742-4690-9-65.

41.

Human immunodeficiency virus (HIV) latency: the major hurdle in HIV eradication.

Tyagi M, Bukrinsky M.

Mol Med. 2012 Sep 25;18:1096-108. doi: 10.2119/molmed.2012.00194. Review.

42.

Liver X receptor agonist inhibits HIV-1 replication and prevents HIV-induced reduction of plasma HDL in humanized mouse model of HIV infection.

Dubrovsky L, Van Duyne R, Senina S, Guendel I, Pushkarsky T, Sviridov D, Kashanchi F, Bukrinsky M.

Biochem Biophys Res Commun. 2012 Mar 2;419(1):95-8. doi: 10.1016/j.bbrc.2012.01.137. Epub 2012 Feb 4.

43.

HIV-1 Nef mobilizes lipid rafts in macrophages through a pathway that competes with ABCA1-dependent cholesterol efflux.

Cui HL, Grant A, Mukhamedova N, Pushkarsky T, Jennelle L, Dubrovsky L, Gaus K, Fitzgerald ML, Sviridov D, Bukrinsky M.

J Lipid Res. 2012 Apr;53(4):696-708. doi: 10.1194/jlr.M023119. Epub 2012 Jan 19.

44.

Cyclophilin A cooperates with MIP-2 to augment neutrophil migration.

Heine SJ, Olive D, Gao JL, Murphy PM, Bukrinsky MI, Constant SL.

J Inflamm Res. 2011;4:93-104. doi: 10.2147/JIR.S20733. Epub 2011 Jun 3.

45.

The level of CD147 expression correlates with cyclophilin-induced signalling and chemotaxis.

Trachtenberg A, Pushkarsky T, Heine S, Constant S, Brichacek B, Bukrinsky M.

BMC Res Notes. 2011 Oct 11;4:396. doi: 10.1186/1756-0500-4-396.

46.

Blocking cyclophilins in the chronic phase of asthma reduces the persistence of leukocytes and disease reactivation.

Stemmy EJ, Balsley MA, Jurjus RA, Damsker JM, Bukrinsky MI, Constant SL.

Am J Respir Cell Mol Biol. 2011 Nov;45(5):991-8. doi: 10.1165/rcmb.2011-0007OC. Epub 2011 Apr 14.

47.

Vpr-host interactions during HIV-1 viral life cycle.

Zhao RY, Li G, Bukrinsky MI.

J Neuroimmune Pharmacol. 2011 Jun;6(2):216-29. doi: 10.1007/s11481-011-9261-z. Epub 2011 Feb 12. Review.

48.

A cell-impermeable cyclosporine A derivative reduces pathology in a mouse model of allergic lung inflammation.

Balsley MA, Malesevic M, Stemmy EJ, Gigley J, Jurjus RA, Herzog D, Bukrinsky MI, Fischer G, Constant SL.

J Immunol. 2010 Dec 15;185(12):7663-70. doi: 10.4049/jimmunol.1001707. Epub 2010 Nov 5.

49.

Mutation of the ATP cassette binding transporter A1 (ABCA1) C-terminus disrupts HIV-1 Nef binding but does not block the Nef enhancement of ABCA1 protein degradation.

Mujawar Z, Tamehiro N, Grant A, Sviridov D, Bukrinsky M, Fitzgerald ML.

Biochemistry. 2010 Sep 28;49(38):8338-49. doi: 10.1021/bi100466q.

50.

Strategies to inhibit viral protein nuclear import: HIV-1 as a target.

Levin A, Loyter A, Bukrinsky M.

Biochim Biophys Acta. 2011 Sep;1813(9):1646-53. doi: 10.1016/j.bbamcr.2010.07.010. Epub 2010 Aug 16. Review.

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