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Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01334-18. doi: 10.1128/AAC.01334-18. Print 2018 Nov.

Implementation of Rapid Diagnostic Testing without Active Stewardship Team Notification for Gram-Positive Blood Cultures in a Community Teaching Hospital.

Author information

1
Department of Pharmacy Services, Mercy Health Saint Mary's, Grand Rapids, Michigan, USA paigebukowski@gmail.com.
2
Department of Pharmacy Services, Mercy Health Saint Mary's, Grand Rapids, Michigan, USA.
3
Division of Infectious Diseases, Mercy Health Saint Mary's, Grand Rapids, Michigan, USA.
4
Michigan State University, College of Human Medicine, Grand Rapids, Michigan, USA.

Abstract

In community hospitals, antimicrobial stewardship team notification of rapid diagnostic testing (RDT) results may not be feasible. A retrospective quasi-experimental study was conducted evaluating 252 adult inpatients with blood cultures positive for Gram-positive cocci in clusters (pre-RDT, n = 143; post-RDT, n = 109). The median time to appropriate therapy was significantly shorter in the post-RDT group (15 versus 0 h, P < 0.001), and the mean length of stay for patients with coagulase-negative staphylococcus was significantly shorter (10.5 versus 7.7 days; P = 0.015).

KEYWORDS:

antimicrobial stewardship; bloodstream infections; coagulase-negative staphylococci; rapid diagnostic testing

PMID:
30150472
PMCID:
PMC6201100
[Available on 2019-04-24]
DOI:
10.1128/AAC.01334-18

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