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Items: 1 to 50 of 148

1.

Merozoite Surface Protein 1 from Plasmodium falciparum Is a Major Target of Opsonizing Antibodies in Individuals with Acquired Immunity against Malaria.

Jäschke A, Coulibaly B, Remarque EJ, Bujard H, Epp C.

Clin Vaccine Immunol. 2017 Nov 6;24(11). pii: e00155-17. doi: 10.1128/CVI.00155-17. Print 2017 Nov.

2.

Multiple Plasmodium falciparum Merozoite Surface Protein 1 Complexes Mediate Merozoite Binding to Human Erythrocytes.

Lin CS, Uboldi AD, Epp C, Bujard H, Tsuboi T, Czabotar PE, Cowman AF.

J Biol Chem. 2016 Apr 1;291(14):7703-15. doi: 10.1074/jbc.M115.698282. Epub 2016 Jan 28.

3.

The merozoite surface protein 1 complex is a platform for binding to human erythrocytes by Plasmodium falciparum.

Lin CS, Uboldi AD, Marapana D, Czabotar PE, Epp C, Bujard H, Taylor NL, Perugini MA, Hodder AN, Cowman AF.

J Biol Chem. 2014 Sep 12;289(37):25655-69. doi: 10.1074/jbc.M114.586495. Epub 2014 Jul 29.

4.

The cellular ratio of immune tolerance (immunoCRIT) is a definite marker for aggressiveness of solid tumors and may explain tumor dissemination patterns.

Türbachova I, Schwachula T, Vasconcelos I, Mustea A, Baldinger T, Jones KA, Bujard H, Olek A, Olek K, Gellhaus K, Braicu I, Könsgen D, Fryer C, Ravot E, Hellwag A, Westerfeld N, Gruss OJ, Meissner M, Hasan MT, Weber M, Hoffmüller U, Zimmermann S, Loddenkemper C, Mahner S, Babel N, Berns E, Adams R, Zeilinger R, Baron U, Vergote I, Maughan T, Marme F, Dickhaus T, Sehouli J, Olek S.

Epigenetics. 2013 Nov;8(11):1226-35. doi: 10.4161/epi.26334. Epub 2013 Sep 26.

PMID:
24071829
5.

Conditional gene expression systems in the transgenic rat brain.

Schönig K, Weber T, Frömmig A, Wendler L, Pesold B, Djandji D, Bujard H, Bartsch D.

BMC Biol. 2012 Sep 3;10:77. doi: 10.1186/1741-7007-10-77.

6.

ΔE1 and high-capacity adenoviral vectors expressing full-length codon-optimized merozoite surface protein 1 for vaccination against Plasmodium falciparum.

Zong S, Kron MW, Epp C, Engler T, Bujard H, Kochanek S, Kreppel F.

J Gene Med. 2011 Dec;13(12):670-9. doi: 10.1002/jgm.1627.

PMID:
22095915
7.

Improved Tet-responsive promoters with minimized background expression.

Loew R, Heinz N, Hampf M, Bujard H, Gossen M.

BMC Biotechnol. 2010 Nov 24;10:81. doi: 10.1186/1472-6750-10-81.

8.

Regulated maturation of malaria merozoite surface protein-1 is essential for parasite growth.

Child MA, Epp C, Bujard H, Blackman MJ.

Mol Microbiol. 2010 Oct;78(1):187-202. doi: 10.1111/j.1365-2958.2010.07324.x. Epub 2010 Feb 8.

9.

The power of reversibility regulating gene activities via tetracycline-controlled transcription.

Schönig K, Bujard H, Gossen M.

Methods Enzymol. 2010;477:429-53. doi: 10.1016/S0076-6879(10)77022-1.

PMID:
20699154
10.

Development of a BAC vector for integration-independent and tight regulation of transgenes in rodents via the Tet system.

Schönig K, Kentner D, Gossen M, Baldinger T, Miao J, Welzel K, Vente A, Bartsch D, Bujard H.

Transgenic Res. 2011 Jun;20(3):709-20. doi: 10.1007/s11248-010-9427-0. Epub 2010 Jul 18.

PMID:
20640885
11.

Use of a new-generation reverse tetracycline transactivator system for quantitative control of conditional gene expression in the murine lung.

Duerr J, Gruner M, Schubert SC, Haberkorn U, Bujard H, Mall MA.

Am J Respir Cell Mol Biol. 2011 Feb;44(2):244-54. doi: 10.1165/rcmb.2009-0115OC. Epub 2010 Apr 15.

PMID:
20395635
12.
13.

EMBO Molecular Medicine--where molecular biology meets clinical research.

Bujard H, Grivell L.

EMBO Mol Med. 2009 Apr;1(1):2-3. doi: 10.1002/emmm.200900012. No abstract available.

14.

Highly B lymphocyte-specific tamoxifen inducible transgene expression of CreER T2 by using the LC-1 locus BAC vector.

Boross P, Breukel C, van Loo PF, van der Kaa J, Claassens JW, Bujard H, Schönig K, Verbeek JS.

Genesis. 2009 Nov;47(11):729-35. doi: 10.1002/dvg.20549.

PMID:
19621440
15.

Expression of CD226 antagonizes apoptotic cell death in murine thymocytes.

Fang L, Zhang X, Miao J, Zhao F, Yang K, Zhuang R, Bujard H, Wei Y, Yang A, Chen L, Jin B.

J Immunol. 2009 May 1;182(9):5453-60. doi: 10.4049/jimmunol.0803090.

16.

Inducible expression of coding and inhibitory RNAs from retargetable genomic loci.

Weidenfeld I, Gossen M, Löw R, Kentner D, Berger S, Görlich D, Bartsch D, Bujard H, Schönig K.

Nucleic Acids Res. 2009 Apr;37(7):e50. doi: 10.1093/nar/gkp108. Epub 2009 Mar 5.

17.

A multifunctional serine protease primes the malaria parasite for red blood cell invasion.

Koussis K, Withers-Martinez C, Yeoh S, Child M, Hackett F, Knuepfer E, Juliano L, Woehlbier U, Bujard H, Blackman MJ.

EMBO J. 2009 Mar 18;28(6):725-35. doi: 10.1038/emboj.2009.22. Epub 2009 Feb 12.

18.

An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice.

Traykova-Brauch M, Schönig K, Greiner O, Miloud T, Jauch A, Bode M, Felsher DW, Glick AB, Kwiatkowski DJ, Bujard H, Horst J, von Knebel Doeberitz M, Niggli FK, Kriz W, Gröne HJ, Koesters R.

Nat Med. 2008 Sep;14(9):979-84. doi: 10.1038/nm.1865.

19.

Reproduction and fertility in wild-type and transgenic mice after orthotopic transplantation of cryopreserved ovaries from 10-d-old mice.

Liu LJ, Xie XY, Zhang RZ, Xu P, Bujard H, Jun M.

Lab Anim (NY). 2008 Aug;37(8):353-7. doi: 10.1038/laban0808-353.

PMID:
18650823
20.

Antibody responses to the merozoite surface protein-1 complex in cerebral malaria patients in India.

Lucchi NW, Tongren JE, Jain V, Nagpal AC, Kauth CW, Woehlbier U, Bujard H, Dash AP, Singh N, Stiles JK, Udhayakumar V.

Malar J. 2008 Jul 4;7:121. doi: 10.1186/1475-2875-7-121.

21.

The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy.

Mocanu MM, Nissen A, Eckermann K, Khlistunova I, Biernat J, Drexler D, Petrova O, Schönig K, Bujard H, Mandelkow E, Zhou L, Rune G, Mandelkow EM.

J Neurosci. 2008 Jan 16;28(3):737-48. doi: 10.1523/JNEUROSCI.2824-07.2008.

22.

The beta-propensity of Tau determines aggregation and synaptic loss in inducible mouse models of tauopathy.

Eckermann K, Mocanu MM, Khlistunova I, Biernat J, Nissen A, Hofmann A, Schönig K, Bujard H, Haemisch A, Mandelkow E, Zhou L, Rune G, Mandelkow EM.

J Biol Chem. 2007 Oct 26;282(43):31755-65. Epub 2007 Aug 23.

23.

System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock.

Kornmann B, Schaad O, Bujard H, Takahashi JS, Schibler U.

PLoS Biol. 2007 Feb;5(2):e34.

24.

Interactions between merozoite surface proteins 1, 6, and 7 of the malaria parasite Plasmodium falciparum.

Kauth CW, Woehlbier U, Kern M, Mekonnen Z, Lutz R, Mücke N, Langowski J, Bujard H.

J Biol Chem. 2006 Oct 20;281(42):31517-27. Epub 2006 Aug 29.

25.

Expression mapping of tetracycline-responsive prion protein promoter: digital atlasing for generating cell-specific disease models.

Boy J, Leergaard TB, Schmidt T, Odeh F, Bichelmeier U, Nuber S, Holzmann C, Wree A, Prusiner SB, Bujard H, Riess O, Bjaalie JG.

Neuroimage. 2006 Nov 1;33(2):449-62. Epub 2006 Aug 23.

PMID:
16931059
26.
27.

Tissue-specific expression of ferritin H regulates cellular iron homoeostasis in vivo.

Wilkinson J 4th, Di X, Schönig K, Buss JL, Kock ND, Cline JM, Saunders TL, Bujard H, Torti SV, Torti FM.

Biochem J. 2006 May 1;395(3):501-7.

28.

Analysis of antibodies directed against merozoite surface protein 1 of the human malaria parasite Plasmodium falciparum.

Woehlbier U, Epp C, Kauth CW, Lutz R, Long CA, Coulibaly B, Kouyaté B, Arevalo-Herrera M, Herrera S, Bujard H.

Infect Immun. 2006 Feb;74(2):1313-22.

29.
30.

Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice.

Viatte L, Nicolas G, Lou DQ, Bennoun M, Lesbordes-Brion JC, Canonne-Hergaux F, Schönig K, Bujard H, Kahn A, Andrews NC, Vaulont S.

Blood. 2006 Apr 1;107(7):2952-8. Epub 2005 Dec 8.

31.

IKK mediates ischemia-induced neuronal death.

Herrmann O, Baumann B, de Lorenzi R, Muhammad S, Zhang W, Kleesiek J, Malfertheiner M, Köhrmann M, Potrovita I, Maegele I, Beyer C, Burke JR, Hasan MT, Bujard H, Wirth T, Pasparakis M, Schwaninger M.

Nat Med. 2005 Dec;11(12):1322-9. Epub 2005 Nov 13.

PMID:
16286924
32.

Stringent doxycycline-dependent control of gene activities using an episomal one-vector system.

Bornkamm GW, Berens C, Kuklik-Roos C, Bechet JM, Laux G, Bachl J, Korndoerfer M, Schlee M, Hölzel M, Malamoussi A, Chapman RD, Nimmerjahn F, Mautner J, Hillen W, Bujard H, Feuillard J.

Nucleic Acids Res. 2005 Sep 7;33(16):e137.

33.

Liver-specific expression of interferon gamma following adenoviral gene transfer controls hepatitis B virus replication in mice.

Dumortier J, Schönig K, Oberwinkler H, Löw R, Giese T, Bujard H, Schirmacher P, Protzer U.

Gene Ther. 2005 Apr;12(8):668-77.

PMID:
15647761
34.

A genetic switch for epilepsy in adult mice.

Krestel HE, Shimshek DR, Jensen V, Nevian T, Kim J, Geng Y, Bast T, Depaulis A, Schonig K, Schwenk F, Bujard H, Hvalby Ø, Sprengel R, Seeburg PH.

J Neurosci. 2004 Nov 17;24(46):10568-78.

35.

Functional fluorescent Ca2+ indicator proteins in transgenic mice under TET control.

Hasan MT, Friedrich RW, Euler T, Larkum ME, Giese G, Both M, Duebel J, Waters J, Bujard H, Griesbeck O, Tsien RY, Nagai T, Miyawaki A, Denk W.

PLoS Biol. 2004 Jun;2(6):e163. Epub 2004 Jun 15.

36.

[Preliminary study on regulable DNA vaccines against Plasmodium falciparum].

Lei JC, Miao J, Li X, Schonig K, Bujard H, Xue CF.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2004 May;20(3):356-9. Chinese.

PMID:
15193238
37.

Optimal design of a single recombinant adeno-associated virus derived from serotypes 1 and 2 to achieve more tightly regulated transgene expression from nonhuman primate muscle.

Chenuaud P, Larcher T, Rabinowitz JE, Provost N, Joussemet B, Bujard H, Samulski RJ, Favre D, Moullier P.

Mol Ther. 2004 Mar;9(3):410-8.

38.

Gene therapy progress and prospects: transcription regulatory systems.

Toniatti C, Bujard H, Cortese R, Ciliberto G.

Gene Ther. 2004 Apr;11(8):649-57. Review.

PMID:
14985790
39.

Use of the tetracycline system for inducible protein synthesis in the kidney.

Gallagher AR, Schönig K, Brown N, Bujard H, Witzgall R.

J Am Soc Nephrol. 2003 Aug;14(8):2042-51.

40.

Conditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis.

Ueberham E, Löw R, Ueberham U, Schönig K, Bujard H, Gebhardt R.

Hepatology. 2003 May;37(5):1067-78.

PMID:
12717387
41.

The merozoite surface protein 1 complex of human malaria parasite Plasmodium falciparum: interactions and arrangements of subunits.

Kauth CW, Epp C, Bujard H, Lutz R.

J Biol Chem. 2003 Jun 20;278(25):22257-64. Epub 2003 Mar 24.

42.

Expression and purification of Plasmodium falciparum MSP-1(42): A malaria vaccine candidate.

Epp C, Kauth CW, Bujard H, Lutz R.

J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Mar 25;786(1-2):61-72.

PMID:
12651002
43.

Doxycycline-regulated lentiviral vector system with a novel reverse transactivator rtTA2S-M2 shows a tight control of gene expression in vitro and in vivo.

Koponen JK, Kankkonen H, Kannasto J, Wirth T, Hillen W, Bujard H, Ylä-Herttuala S.

Gene Ther. 2003 Mar;10(6):459-66.

PMID:
12621450
44.

Construction of an rtTA2(s)-m2/tts(kid)-based transcription regulatory switch that displays no basal activity, good inducibility, and high responsiveness to doxycycline in mice and non-human primates.

Lamartina S, Silvi L, Roscilli G, Casimiro D, Simon AJ, Davies ME, Shiver JW, Rinaudo CD, Zampaglione I, Fattori E, Colloca S, Gonzalez Paz O, Laufer R, Bujard H, Cortese R, Ciliberto G, Toniatti C.

Mol Ther. 2003 Feb;7(2):271-80.

45.

Stringent doxycycline dependent control of CRE recombinase in vivo.

Schönig K, Schwenk F, Rajewsky K, Bujard H.

Nucleic Acids Res. 2002 Dec 1;30(23):e134.

46.

Studying gene function in eukaryotes by conditional gene inactivation.

Gossen M, Bujard H.

Annu Rev Genet. 2002;36:153-73. Epub 2002 Jun 11. Review.

PMID:
12429690
47.

Tight control of gene expression by a helper-dependent adenovirus vector carrying the rtTA2(s)-M2 tetracycline transactivator and repressor system.

Salucci V, Scarito A, Aurisicchio L, Lamartina S, Nicolaus G, Giampaoli S, Gonzalez-Paz O, Toniatti C, Bujard H, Hillen W, Ciliberto G, Palombo F.

Gene Ther. 2002 Nov;9(21):1415-21.

48.

Generating conditional mouse mutants via tetracycline-controlled gene expression.

Schönig K, Bujard H.

Methods Mol Biol. 2003;209:69-104. No abstract available.

PMID:
12357963
49.

Robust and efficient regulation of transgene expression in vivo by improved tetracycline-dependent lentiviral vectors.

Vigna E, Cavalieri S, Ailles L, Geuna M, Loew R, Bujard H, Naldini L.

Mol Ther. 2002 Mar;5(3):252-61.

50.

Regulated and prolonged expression of mIFN(alpha) in immunocompetent mice mediated by a helper-dependent adenovirus vector.

Aurisicchio L, Bujard H, Hillen W, Cortese R, Ciliberto G, La Monica N, Palombo F.

Gene Ther. 2001 Dec;8(24):1817-25.

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