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Compound blue nevus: a reappraisal of the concept in the genomic era.

Jaquemus J, Perron E, Buisson A, Ferrara G, Haddad V, de la Fouchardiere A.

Virchows Arch. 2019 Nov 21. doi: 10.1007/s00428-019-02667-w. [Epub ahead of print]


Reduction in the neuronal surface of post- and pre-synaptic GABAB receptors in the hippocampus in a mouse model of Alzheimer´s disease.

Martín-Belmonte A, Aguado C, Alfaro-Ruíz R, Moreno-Martínez AE, de la Ossa L, Martínez-Hernández J, Buisson A, Früh S, Bettler B, Shigemoto R, Fukazawa Y, Luján R.

Brain Pathol. 2019 Nov 15. doi: 10.1111/bpa.12802. [Epub ahead of print]


Macrophages Inability to Mediate Adherent-Invasive E. coli Replication is Linked to Autophagy in Crohn's Disease Patients.

Buisson A, Douadi C, Ouchchane L, Goutte M, Hugot JP, Dubois A, Minet-Quinard R, Bouvier D, Bommelaer G, Vazeille E, Barnich N.

Cells. 2019 Nov 5;8(11). pii: E1394. doi: 10.3390/cells8111394.


Clinical factors associated with prolonged response and survival under olaparib as maintenance therapy in BRCA mutated ovarian cancers.

Labidi-Galy SI, de La Motte Rouge T, Derbel O, Wolfer A, Kalbacher E, Olivier T, Combes JD, Heimgartner-Hu K, Tredan O, Guevara H, Heudel PE, Reverdy T, Bazan F, Heinzelmann-Schwarz V, Fehr M, de Castelbajac V, Vaflard P, Crivelli L, Bonadona V, Viassolo V, Buisson A, Golmard L, Rodrigues M, Ray-Coquard I.

Gynecol Oncol. 2019 Nov;155(2):262-269. doi: 10.1016/j.ygyno.2019.09.008. Epub 2019 Oct 8.


Supravalvular Aortic Stenosis Caused by a Familial Chromosome 7 Inversion Disrupting the ELN Gene Uncovered by Whole-Genome Sequencing.

Pons L, Bouvagnet P, Bakloul M, Di Filippo S, Buisson A, Chatron N, Labalme A, Metton O, Mitchell J, Diguet F, Rollat-Farnier PA, Sanlaville D, Schluth-Bolard C.

Mol Syndromol. 2019 Jul;10(4):209-213. doi: 10.1159/000500215. Epub 2019 May 21.


Amyloid Fibers Reveal Themselves With Near-Infrared.

Buisson A, Decressac M.

Mov Disord. 2019 Nov;34(11):1643. doi: 10.1002/mds.27852. Epub 2019 Sep 16. No abstract available.


Oral Curcumin No More Effective Than Placebo in Preventing Recurrence of Crohn's Disease After Surgery in a Randomized Controlled Trial.

Bommelaer G, Laharie D, Nancey S, Hebuterne X, Roblin X, Nachury M, Peyrin-Biroulet L, Fumery M, Richard D, Pereira B, Goutte M, Buisson A; POPCUR study group.

Clin Gastroenterol Hepatol. 2019 Aug 27. pii: S1542-3565(19)30916-4. doi: 10.1016/j.cgh.2019.08.041. [Epub ahead of print]


Impact of a checklist used by pharmacists on hospital antimicrobial use: a patient-level interrupted time series study.

Fortier M, Pistre P, Ferreira V, Pinsonneault M, Charbonneau JM, Proulx C, Buisson A, Morency-Potvin P, Williamson D, Ang A.

J Hosp Infect. 2019 Nov;103(3):251-258. doi: 10.1016/j.jhin.2019.06.009. Epub 2019 Jun 21.


Efficacy of Tumor Necrosis Factor Antagonist Treatment in Patients With Refractory Ulcerative Proctitis.

Pineton de Chambrun G, Amiot A, Bouguen G, Viennot S, Altwegg R, Louis E, Collins M, Fumery M, Poullenot F, Armengol L, Buisson A, Abitbol V, Laharie D, Seksik P, Nancey S, Blanc P, Bouhnik Y, Pariente B, Peyrin-Biroulet L; PROTECT-GETAID study group.

Clin Gastroenterol Hepatol. 2019 Jun 13. pii: S1542-3565(19)30642-1. doi: 10.1016/j.cgh.2019.05.060. [Epub ahead of print]


Three-year effectiveness and safety of vedolizumab therapy for inflammatory bowel disease: a prospective multi-centre cohort study.

Amiot A, Serrero M, Peyrin-Biroulet L, Filippi J, Pariente B, Roblin X, Buisson A, Stefanescu C, Trang-Poisson C, Altwegg R, Marteau P, Vaysse T, Bourrier A, Nancey S, Laharie D, Allez M, Savoye G, Moreau J, Vuitton L, Viennot S, Bouguen G, Abitbol V, Fumery M, Gagniere C, Bouhnik Y; OBSERV-IBD study group, the GETAID.

Aliment Pharmacol Ther. 2019 Jul;50(1):40-53. doi: 10.1111/apt.15294. Epub 2019 Jun 5.


Combined evaluation of biomarkers as predictor of maintained remission in Crohn's disease.

Sollelis E, Quinard RM, Bouguen G, Goutte M, Goutorbe F, Bouvier D, Pereira B, Bommelaer G, Buisson A.

World J Gastroenterol. 2019 May 21;25(19):2354-2364. doi: 10.3748/wjg.v25.i19.2354.


Prominence of ileal mucosa-associated microbiota to predict postoperative endoscopic recurrence in Crohn's disease.

Sokol H, Brot L, Stefanescu C, Auzolle C, Barnich N, Buisson A, Fumery M, Pariente B, Le Bourhis L, Treton X, Nancey S, Allez M, Seksik P; REMIND Study Group Investigators.

Gut. 2019 May 29. pii: gutjnl-2019-318719. doi: 10.1136/gutjnl-2019-318719. [Epub ahead of print]


Monitoring a Combination of Calprotectin and Infliximab Identifies Patients With Mucosal Healing of Crohn's Disease.

Dreesen E, Baert F, Laharie D, Bossuyt P, Bouhnik Y, Buisson A, Lambrecht G, Louis E, Oldenburg B, Pariente B, Pierik M, van der Woude CJ, D'Haens G, Vermeire S, Gils A.

Clin Gastroenterol Hepatol. 2019 May 22. pii: S1542-3565(19)30551-8. doi: 10.1016/j.cgh.2019.05.029. [Epub ahead of print]


39. Dissémination méningée et syndrome confusionnel.

Buisson A, Hsibe M, Velentza A, Ketz F, Pautas E.

Soins Gerontol. 2019 May - Jun;24(137):43-44. doi: 10.1016/j.sger.2019.03.012. French. No abstract available.


Association Between Microscopic Lesions at Ileal Resection Margin and Recurrence After Surgery in Patients With Crohn's Disease.

Hammoudi N, Cazals-Hatem D, Auzolle C, Gardair C, Ngollo M, Bottois H, Nancey S, Pariente B, Buisson A, Treton X, Fumery M, Bezault M, Seksik P, Le Bourhis L; REMIND Study Group Investigators, Flejou JF, Allez M.

Clin Gastroenterol Hepatol. 2019 Apr 28. pii: S1542-3565(19)30435-5. doi: 10.1016/j.cgh.2019.04.045. [Epub ahead of print]


Exome sequencing and pathogenicity-network analysis of five French families implicate mTOR signalling and autophagy in familial sarcoidosis.

Calender A, Lim CX, Weichhart T, Buisson A, Besnard V, Rollat-Farnier PA, Bardel C, Roy P, Cottin V, Devouassoux G, Finat A, Pinson S, Lebecque S, Nunes H, Israel-Biet D, Bentaher A, Valeyre D, Pacheco Y; in the frame of GSF (Group Sarcoidosis France).

Eur Respir J. 2019 Aug 1;54(2). pii: 1900430. doi: 10.1183/13993003.00430-2019. Print 2019 Aug. No abstract available.


Rapid Desensitization to Adalimumab Is Associated With Decreased Basophil Sensitivity.

Thévenot J, Ferrier le Bouëdec MC, Buisson A, Bommelaer G, D'Incan M, Rouzaire P.

J Investig Allergol Clin Immunol. 2019 Apr;29(2):141-143. doi: 10.18176/jiaci.0350. No abstract available.


[Interest of extrahospital multidisciplinary unit of neuro-psycho-geriatric intervened in nursing home: Analysis of 288 interventions].

Buisson A, Ojardias E, Viceriat A, Fakra É, Celarier T.

Encephale. 2019 Sep;45(4):327-332. doi: 10.1016/j.encep.2018.09.001. Epub 2019 Mar 14. French.


Impact of inflammatory bowel diseases on working life: A French nationwide survey.

Le Berre C, Peyrin-Biroulet L, Buisson A, Olympie A, Ravel MH, Bienenfeld C, Gonzalez F.

Dig Liver Dis. 2019 Jul;51(7):961-966. doi: 10.1016/j.dld.2019.01.024. Epub 2019 Feb 11.


Adalimumab for patients with Crohn's disease complicated by intra-abdominal abscess: a multicentre, prospective, observational cohort study.

Pineton de Chambrun G, Pariente B, Seksik P, Altwegg R, Vuitton L, Stefasnescu C, Nancey S, Aubourg A, Serrero M, Peyrin-Biroulet L, Filippi J, Viennot S, Abitbol V, Boualit M, Boureille A, Moreau J, Buisson A, Roblin X, Nachury M, Zappa M, Lambert J, Bouhnik Y; GETAID-MICA study group.

J Crohns Colitis. 2019 Jan 25;13(Supplement_1):S616. doi: 10.1093/ecco-jcc/jjz045.


T cell clonal expansions in ileal Crohn's disease are associated with smoking behaviour and postoperative recurrence.

Allez M, Auzolle C, Ngollo M, Bottois H, Chardiny V, Corraliza AM, Salas A, Perez K, Stefanescu C, Nancey S, Buisson A, Pariente B, Fumery M, Sokol H, Tréton X, Barnich N, Seksik P, Le Bourhis L; REMIND Study Group.

Gut. 2019 Nov;68(11):1961-1970. doi: 10.1136/gutjnl-2018-317878. Epub 2019 Feb 12.


Metabolic adaptation of adherent-invasive Escherichia coli to exposure to bile salts.

Delmas J, Gibold L, Faïs T, Batista S, Leremboure M, Sinel C, Vazeille E, Cattoir V, Buisson A, Barnich N, Dalmasso G, Bonnet R.

Sci Rep. 2019 Feb 18;9(1):2175. doi: 10.1038/s41598-019-38628-1.


Faecal Calprotectin Is a Very Reliable Tool to Predict and Monitor the Risk of Relapse After Therapeutic De-escalation in Patients With Inflammatory Bowel Diseases.

Buisson A, Mak WY, Andersen MJ, Lei D, Kahn SA, Pekow J, Cohen RD, Zmeter N, Pereira B, Rubin DT.

J Crohns Colitis. 2019 Aug 14;13(8):1012-1024. doi: 10.1093/ecco-jcc/jjz023.


Autophagy Is Required for Memory Formation and Reverses Age-Related Memory Decline.

Glatigny M, Moriceau S, Rivagorda M, Ramos-Brossier M, Nascimbeni AC, Lante F, Shanley MR, Boudarene N, Rousseaud A, Friedman AK, Settembre C, Kuperwasser N, Friedlander G, Buisson A, Morel E, Codogno P, Oury F.

Curr Biol. 2019 Feb 4;29(3):435-448.e8. doi: 10.1016/j.cub.2018.12.021. Epub 2019 Jan 17.


BRCA1/BRCA2 germline mutations and chemotherapy-related hematological toxicity in breast cancer patients.

Friedlaender A, Vuilleumier A, Viassolo V, Ayme A, De Talhouet S, Combes JD, Peron J, Bodmer A, Giraud S, Buisson A, Bonadona V, Gauchat-Bouchardy I, Tredan O, Chappuis PO, Labidi-Galy SI.

Breast Cancer Res Treat. 2019 Apr;174(3):775-783. doi: 10.1007/s10549-018-05127-2. Epub 2019 Jan 11.


Synaptotoxicity in Alzheimer's Disease Involved a Dysregulation of Actin Cytoskeleton Dynamics through Cofilin 1 Phosphorylation.

Rush T, Martinez-Hernandez J, Dollmeyer M, Frandemiche ML, Borel E, Boisseau S, Jacquier-Sarlin M, Buisson A.

J Neurosci. 2018 Nov 28;38(48):10349-10361. doi: 10.1523/JNEUROSCI.1409-18.2018. Epub 2018 Oct 19.


A key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines.

Peris L, Bisbal M, Martinez-Hernandez J, Saoudi Y, Jonckheere J, Rolland M, Sebastien M, Brocard J, Denarier E, Bosc C, Guerin C, Gory-Fauré S, Deloulme JC, Lanté F, Arnal I, Buisson A, Goldberg Y, Blanchoin L, Delphin C, Andrieux A.

Nat Commun. 2018 Sep 17;9(1):3775. doi: 10.1038/s41467-018-05869-z.


Bowel wall healing assessed using magnetic resonance imaging predicts sustained clinical remission and decreased risk of surgery in Crohn's disease.

Buisson A, Hordonneau C, Goutorbe F, Allimant C, Goutte M, Reymond M, Pereira B, Bommelaer G.

J Gastroenterol. 2019 Apr;54(4):312-320. doi: 10.1007/s00535-018-1505-8. Epub 2018 Aug 30.


Male gender, active smoking and previous intestinal resection are risk factors for post-operative endoscopic recurrence in Crohn's disease: results from a prospective cohort study.

Auzolle C, Nancey S, Tran-Minh ML, Buisson A, Pariente B, Stefanescu C, Fumery M, Marteau P, Treton X, Hammoudi N; REMIND Study Group Investigators, Jouven X, Seksik P, Allez M.

Aliment Pharmacol Ther. 2018 Nov;48(9):924-932. doi: 10.1111/apt.14944. Epub 2018 Aug 20.


Risk of serious infection in healthcare workers with inflammatory bowel disease: a case-control study of the Groupe d'Etude Thérapeutique des Affections Inflammatoires du tube Digestif (GETAID).

Gagnière C, Bourrier A, Seksik P, Gornet JM, DeWit O, Nancey S, Altwegg R, Abitbol V, Laharie D, Reenaers C, Buisson A, Pariente B, Viennot S, Vuitton L, Stefanescu C, Marteau P, Bouguen G, Cosnes J, Amiot A; GETAID INFOPRO study group.

Aliment Pharmacol Ther. 2018 Oct;48(7):713-722. doi: 10.1111/apt.14926. Epub 2018 Aug 2.


Whole exome sequencing in three families segregating a pediatric case of sarcoidosis.

Calender A, Rollat Farnier PA, Buisson A, Pinson S, Bentaher A, Lebecque S, Corvol H, Abou Taam R, Houdouin V, Bardel C, Roy P, Devouassoux G, Cottin V, Seve P, Bernaudin JF, Lim CX, Weichhart T, Valeyre D, Pacheco Y, Clement A, Nathan N; in the frame of GSF (Groupe Sarcoïdose France).

BMC Med Genomics. 2018 Mar 6;11(1):23. doi: 10.1186/s12920-018-0338-x.


IBD-INFO Questionnaire: A Multicenter French Up-to-Date Survey of Patient Knowledge in Inflammatory Bowel Disease.

Danion P, Buisson A, Roblin X, Mathieu N, Charlois AL, Borgerding JN, Williet N, Del Tedesco E, Flourié B, Nancey S, Boschetti G.

Inflamm Bowel Dis. 2018 Apr 23;24(5):943-952. doi: 10.1093/ibd/izx073.


How to strengthen the presence of patients in health technology assessments conducted by the health authorities.

Mamzer MF, Dubois S, Saout C; participants of Round Table «Topical Subject» of Giens XXXIII, Albin N, Béhier JM, Buisson A, Diebolt V, Delaitre O, Duguet C, Fagon JY, Gaillard S, Le Jeunne C, Mazars R, Micallef J, Nabarette H, Piazza L, Raynaud C, Varoqueaux N.

Therapie. 2018 Feb;73(1):95-105. doi: 10.1016/j.therap.2017.11.004. Epub 2017 Dec 21. French.


Fecal Calprotectin in Assessing Endoscopic and Histological Remission in Patients with Ulcerative Colitis.

Mak WY, Buisson A, Andersen MJ Jr, Lei D, Pekow J, Cohen RD, Kahn SA, Pereira B, Rubin DT.

Dig Dis Sci. 2018 May;63(5):1294-1301. doi: 10.1007/s10620-018-4980-0. Epub 2018 Feb 22.


Faecal calprotectin and magnetic resonance imaging in detecting Crohn's disease endoscopic postoperative recurrence.

Baillet P, Cadiot G, Goutte M, Goutorbe F, Brixi H, Hoeffel C, Allimant C, Reymond M, Obritin-Guilhen H, Magnin B, Bommelaer G, Pereira B, Hordonneau C, Buisson A.

World J Gastroenterol. 2018 Feb 7;24(5):641-650. doi: 10.3748/wjg.v24.i5.641.


Systematic Review With Meta-Analysis: Anti-TNF Therapy in Refractory Pouchitis and Crohn's Disease-Like Complications of the Pouch After Ileal Pouch-Anal Anastomosis Following Colectomy for Ulcerative Colitis.

Huguet M, Pereira B, Goutte M, Goutorbe F, Dubois A, Bommelaer G, Buisson A.

Inflamm Bowel Dis. 2018 Jan 18;24(2):261-268. doi: 10.1093/ibd/izx049.


Increasing Infliximab Dose Based on Symptoms, Biomarkers, and Serum Drug Concentrations Does Not Increase Clinical, Endoscopic, and Corticosteroid-Free Remission in Patients With Active Luminal Crohn's Disease.

D'Haens G, Vermeire S, Lambrecht G, Baert F, Bossuyt P, Pariente B, Buisson A, Bouhnik Y, Filippi J, Vander Woude J, Van Hootegem P, Moreau J, Louis E, Franchimont D, De Vos M, Mana F, Peyrin-Biroulet L, Brixi H, Allez M, Caenepeel P, Aubourg A, Oldenburg B, Pierik M, Gils A, Chevret S, Laharie D; GETAID.

Gastroenterology. 2018 Apr;154(5):1343-1351.e1. doi: 10.1053/j.gastro.2018.01.004. Epub 2018 Jan 6.


Long-term efficacy and safety of ustekinumab in 122 refractory Crohn's disease patients: a multicentre experience.

Wils P, Bouhnik Y, Michetti P, Flourie B, Brixi H, Bourrier A, Allez M, Duclos B, Serrero M, Buisson A, Amiot A, Fumery M, Roblin X, Peyrin-Biroulet L, Filippi J, Bouguen G, Abitbol V, Coffin B, Simon M, Laharie D, Pariente B; Groupe d'Etude Thérapeutique des Affections Inflammatoires du Tube Digestif (GETAID).

Aliment Pharmacol Ther. 2018 Mar;47(5):588-595. doi: 10.1111/apt.14487. Epub 2018 Jan 8.


Impact of vedolizumab therapy on extra-intestinal manifestations in patients with inflammatory bowel disease: a multicentre cohort study nested in the OBSERV-IBD cohort.

Tadbiri S, Peyrin-Biroulet L, Serrero M, Filippi J, Pariente B, Roblin X, Buisson A, Stefanescu C, Trang-Poisson C, Altwegg R, Marteau P, Vaysse T, Bourrier A, Nancey S, Laharie D, Allez M, Savoye G, Gilletta C, Gagniere C, Vuitton L, Viennot S, Aubourg A, Pelletier AL, Bouguen G, Abitbol V, Fumery M, Claudepierre P, Bouhnik Y, Amiot A; GETAID OBSERV-IBD study group.

Aliment Pharmacol Ther. 2018 Feb;47(4):485-493. doi: 10.1111/apt.14419. Epub 2017 Dec 18.


Predictive performance of four frailty screening tools in community-dwelling elderly.

Bongue B, Buisson A, Dupre C, Beland F, Gonthier R, Crawford-Achour É.

BMC Geriatr. 2017 Nov 10;17(1):262. doi: 10.1186/s12877-017-0633-y.


Location of Mutation in BRCA2 Gene and Survival in Patients with Ovarian Cancer.

Labidi-Galy SI, Olivier T, Rodrigues M, Ferraioli D, Derbel O, Bodmer A, Petignat P, Rak B, Chopin N, Tredan O, Heudel PE, Stuckelberger S, Meeus P, Meraldi P, Viassolo V, Ayme A, Chappuis PO, Stern MH, Houdayer C, Stoppa-Lyonnet D, Buisson A, Golmard L, Bonadona V, Ray-Coquard I.

Clin Cancer Res. 2018 Jan 15;24(2):326-333. doi: 10.1158/1078-0432.CCR-17-2136. Epub 2017 Oct 30.


Inflammatory gastrointestinal diseases associated with PD-1 blockade antibodies.

Collins M, Michot JM, Danlos FX, Mussini C, Soularue E, Mateus C, Loirat D, Buisson A, Rosa I, Lambotte O, Laghouati S, Chaput N, Coutzac C, Voisin AL, Soria JC, Marabelle A, Champiat S, Robert C, Carbonnel F.

Ann Oncol. 2017 Nov 1;28(11):2860-2865. doi: 10.1093/annonc/mdx403.


Efficacy and safety of golimumab in Crohn's disease: a French national retrospective study.

Martineau C, Flourié B, Wils P, Vaysse T, Altwegg R, Buisson A, Amiot A, Pineton de Chambrun G, Abitbol V, Fumery M, Hébuterne X, Viennot S, Laharie D, Beaugerie L, Nancey S, Sokol H; Goli-Crohn Study Group.

Aliment Pharmacol Ther. 2017 Dec;46(11-12):1077-1084. doi: 10.1111/apt.14371. Epub 2017 Oct 13.


GluN2B Subunit Labeling with Fluorescent Probes and High-Resolution Live Imaging.

Perrio C, Nicole O, Buisson A.

Methods Mol Biol. 2017;1677:171-183. doi: 10.1007/978-1-4939-7321-7_9.


Magnetic resonance index of activity (MaRIA) and Clermont score are highly and equally effective MRI indices in detecting mucosal healing in Crohn's disease.

Buisson A, Pereira B, Goutte M, Reymond M, Allimant C, Obritin-Guilhen H, Bommelaer G, Hordonneau C.

Dig Liver Dis. 2017 Nov;49(11):1211-1217. doi: 10.1016/j.dld.2017.08.033. Epub 2017 Aug 31.


Involvement of CRF2 signaling in enterocyte differentiation.

Ducarouge B, Pelissier-Rota M, Powell R, Buisson A, Bonaz B, Jacquier-Sarlin M.

World J Gastroenterol. 2017 Jul 28;23(28):5127-5145. doi: 10.3748/wjg.v23.i28.5127.


Transmural Healing and MRI Remission: New Promising Therapeutic Targets in Crohn's Disease.

Buisson A, Hordonneau C, Deepak P.

Inflamm Bowel Dis. 2017 Sep;23(9):E44-E45. doi: 10.1097/MIB.0000000000001219. No abstract available.


Fecal Matrix Metalloprotease-9 and Lipocalin-2 as Biomarkers in Detecting Endoscopic Activity in Patients With Inflammatory Bowel Diseases.

Buisson A, Vazeille E, Minet-Quinard R, Goutte M, Bouvier D, Goutorbe F, Pereira B, Barnich N, Bommelaer G.

J Clin Gastroenterol. 2018 Aug;52(7):e53-e62. doi: 10.1097/MCG.0000000000000837.


TRPA1 channels promote astrocytic Ca2+ hyperactivity and synaptic dysfunction mediated by oligomeric forms of amyloid-β peptide.

Bosson A, Paumier A, Boisseau S, Jacquier-Sarlin M, Buisson A, Albrieux M.

Mol Neurodegener. 2017 Jul 6;12(1):53. doi: 10.1186/s13024-017-0194-8.


One-year effectiveness and safety of vedolizumab therapy for inflammatory bowel disease: a prospective multicentre cohort study.

Amiot A, Serrero M, Peyrin-Biroulet L, Filippi J, Pariente B, Roblin X, Buisson A, Stefanescu C, Trang-Poisson C, Altwegg R, Marteau P, Vaysse T, Bourrier A, Nancey S, Laharie D, Allez M, Savoye G, Moreau J, Vuitton L, Viennot S, Aubourg A, Pelletier AL, Bouguen G, Abitbol V, Gagniere C, Bouhnik Y; OBSERV-IBD study group and the GETAID.

Aliment Pharmacol Ther. 2017 Aug;46(3):310-321. doi: 10.1111/apt.14167. Epub 2017 Jun 8.

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