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Items: 35


Benzoquinone, a leukemogenic metabolite of benzene, catalytically inhibits the protein tyrosine phosphatase PTPN2 and alters STAT1 signaling.

Duval R, Bui LC, Mathieu C, Nian Q, Berthelet J, Xu X, Haddad I, Vinh J, Dupret JM, Busi F, Guidez F, Chomienne C, Rodrigues-Lima F.

J Biol Chem. 2019 Aug 16;294(33):12483-12494. doi: 10.1074/jbc.RA119.008666. Epub 2019 Jun 27.


T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug Etoposide.

Nian Q, Berthelet J, Zhang W, Bui LC, Liu R, Xu X, Duval R, Ganesan S, Leger T, Chomienne C, Busi F, Guidez F, Dupret JM, Rodrigues Lima F.

Mol Pharmacol. 2019 Aug;96(2):297-306. doi: 10.1124/mol.119.116319. Epub 2019 Jun 20.


A readout of metabolic efficiency in arylamine N-acetyltransferase-deficient mice reveals minor energy metabolism changes.

Denis RGP, Busi F, Castel J, Morel C, Zhang W, Bui LC, Sugamori KS, Prokopec SD, Boutros PC, Grant DM, Rodrigues-Lima F, Luquet S, Dupret JM.

FEBS Lett. 2019 Apr;593(8):831-841. doi: 10.1002/1873-3468.13357. Epub 2019 Mar 22.


Alterations in the Serotonin and Dopamine Pathways by Cystathionine Beta Synthase Overexpression in Murine Brain.

London J, Ndiaye FK, Bui LC, Souchet B, Daubigney F, Magnan C, Luquet S, Dairou J, Janel N, Rouch C.

Mol Neurobiol. 2019 Jun;56(6):3958-3971. doi: 10.1007/s12035-018-1323-2. Epub 2018 Sep 20.


DYRK1A inhibition and cognitive rescue in a Down syndrome mouse model are induced by new fluoro-DANDY derivatives.

Neumann F, Gourdain S, Albac C, Dekker AD, Bui LC, Dairou J, Schmitz-Afonso I, Hue N, Rodrigues-Lima F, Delabar JM, Potier MC, Le Caër JP, Touboul D, Delatour B, Cariou K, Dodd RH.

Sci Rep. 2018 Feb 12;8(1):2859. doi: 10.1038/s41598-018-20984-z.


Human Arylamine N-Acetyltransferase 1 Is Inhibited by the Dithiocarbamate Pesticide Thiram.

Xu X, Mathieu C, Berthelet J, Duval R, Bui LC, Busi F, Dupret JM, Rodrigues-Lima F.

Mol Pharmacol. 2017 Sep;92(3):358-365. doi: 10.1124/mol.117.108662. Epub 2017 Jul 3.


Oxidative potential of particulate matter 2.5 as predictive indicator of cellular stress.

Crobeddu B, Aragao-Santiago L, Bui LC, Boland S, Baeza Squiban A.

Environ Pollut. 2017 Nov;230:125-133. doi: 10.1016/j.envpol.2017.06.051. Epub 2017 Jun 22.


Overexpression of the DYRK1A Gene (Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A) Induces Alterations of the Serotoninergic and Dopaminergic Processing in Murine Brain Tissues.

London J, Rouch C, Bui LC, Assayag E, Souchet B, Daubigney F, Medjaoui H, Luquet S, Magnan C, Delabar JM, Dairou J, Janel N.

Mol Neurobiol. 2018 May;55(5):3822-3831. doi: 10.1007/s12035-017-0591-6. Epub 2017 May 25.


Molecular Mechanisms of Allosteric Inhibition of Brain Glycogen Phosphorylase by Neurotoxic Dithiocarbamate Chemicals.

Mathieu C, Bui LC, Petit E, Haddad I, Agbulut O, Vinh J, Dupret JM, Rodrigues-Lima F.

J Biol Chem. 2017 Feb 3;292(5):1603-1612. doi: 10.1074/jbc.M116.766725. Epub 2016 Dec 13.


An Isozyme-specific Redox Switch in Human Brain Glycogen Phosphorylase Modulates Its Allosteric Activation by AMP.

Mathieu C, Duval R, Cocaign A, Petit E, Bui LC, Haddad I, Vinh J, Etchebest C, Dupret JM, Rodrigues-Lima F.

J Biol Chem. 2016 Nov 11;291(46):23842-23853. doi: 10.1074/jbc.M116.757062. Epub 2016 Sep 22.


Identification of cancer chemopreventive isothiocyanates as direct inhibitors of the arylamine N-acetyltransferase-dependent acetylation and bioactivation of aromatic amine carcinogens.

Duval R, Xu X, Bui LC, Mathieu C, Petit E, Cariou K, Dodd RH, Dupret JM, Rodrigues-Lima F.

Oncotarget. 2016 Feb 23;7(8):8688-99. doi: 10.18632/oncotarget.7086.


Regulation of Aquaporin 3 Expression by the AhR Pathway Is Critical to Cell Migration.

Bui LC, Tomkiewicz C, Pierre S, Chevallier A, Barouki R, Coumoul X.

Toxicol Sci. 2016 Jan;149(1):158-66. doi: 10.1093/toxsci/kfv221. Epub 2015 Oct 9.


An acetyltransferase assay for CREB-binding protein based on reverse phase-ultra-fast liquid chromatography of fluorescent histone H3 peptides.

Duval R, Fritsch L, Bui LC, Berthelet J, Guidez F, Mathieu C, Dupret JM, Chomienne C, Ait-Si-Ali S, Rodrigues-Lima F.

Anal Biochem. 2015 Oct 1;486:35-7. doi: 10.1016/j.ab.2015.06.024. Epub 2015 Jun 20.


Screen for soil fungi highly resistant to dichloroaniline uncovers mostly Fusarium species.

Chan Ho Tong L, Dairou J, Bui LC, Bouillon J, Rodrigues-Lima F, Dupret JM, Silar P.

Fungal Genet Biol. 2015 Aug;81:82-7. doi: 10.1016/j.fgb.2015.05.011. Epub 2015 Jun 8.


A RP-UFLC Assay for Protein Tyrosine Phosphatases: Focus on Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2).

Duval R, Bui LC, Berthelet J, Dairou J, Mathieu C, Guidez F, Dupret JM, Cools J, Chomienne C, Rodrigues-Lima F.

Sci Rep. 2015 Jun 4;5:10750. doi: 10.1038/srep10750.


Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues.

Richarme G, Mihoub M, Dairou J, Bui LC, Leger T, Lamouri A.

J Biol Chem. 2015 Jan 16;290(3):1885-97. doi: 10.1074/jbc.M114.597815. Epub 2014 Nov 21.


Activation of the aryl hydrocarbon receptor by carcinogenic aromatic amines and modulatory effects of their N-acetylated metabolites.

Juricek L, Bui LC, Busi F, Pierre S, Guyot E, Lamouri A, Dupret JM, Barouki R, Coumoul X, Rodrigues-Lima F.

Arch Toxicol. 2015 Dec;89(12):2403-12. doi: 10.1007/s00204-014-1367-7. Epub 2014 Sep 17.


A high-performance liquid chromatography assay for Dyrk1a, a Down syndrome-associated kinase.

Bui LC, Tabouy L, Busi F, Dupret JM, Janel N, Planque C, Delabar JM, Rodrigues-Lima F, Dairou J.

Anal Biochem. 2014 Mar 15;449:172-8. doi: 10.1016/j.ab.2013.12.024. Epub 2013 Dec 25.


Development of DANDYs, new 3,5-diaryl-7-azaindoles demonstrating potent DYRK1A kinase inhibitory activity.

Gourdain S, Dairou J, Denhez C, Bui LC, Rodrigues-Lima F, Janel N, Delabar JM, Cariou K, Dodd RH.

J Med Chem. 2013 Dec 12;56(23):9569-85. doi: 10.1021/jm401049v. Epub 2013 Nov 19.


Aryl hydrocarbon receptor-dependent induction of liver fibrosis by dioxin.

Pierre S, Chevallier A, Teixeira-Clerc F, Ambolet-Camoit A, Bui LC, Bats AS, Fournet JC, Fernandez-Salguero P, Aggerbeck M, Lotersztajn S, Barouki R, Coumoul X.

Toxicol Sci. 2014 Jan;137(1):114-24. doi: 10.1093/toxsci/kft236. Epub 2013 Oct 23.


Fatty acid transporter CD36 mediates hypothalamic effect of fatty acids on food intake in rats.

Moullé VS, Le Foll C, Philippe E, Kassis N, Rouch C, Marsollier N, Bui LC, Guissard C, Dairou J, Lorsignol A, Pénicaud L, Levin BE, Cruciani-Guglielmacci C, Magnan C.

PLoS One. 2013 Sep 6;8(9):e74021. doi: 10.1371/journal.pone.0074021. eCollection 2013.


Biotransformation of Trichoderma spp. and their tolerance to aromatic amines, a major class of pollutants.

Cocaign A, Bui LC, Silar P, Chan Ho Tong L, Busi F, Lamouri A, Mougin C, Rodrigues-Lima F, Dupret JM, Dairou J.

Appl Environ Microbiol. 2013 Aug;79(15):4719-26. doi: 10.1128/AEM.00989-13. Epub 2013 May 31.


Acrolein, an α,β-unsaturated aldehyde, irreversibly inhibits the acetylation of aromatic amine xenobiotics by human arylamine N-acetyltransferase 1.

Bui LC, Manaa A, Xu X, Duval R, Busi F, Dupret JM, Rodrigues-Lima F, Dairou J.

Drug Metab Dispos. 2013 Jul;41(7):1300-5. doi: 10.1124/dmd.113.052258. Epub 2013 Apr 30.


Hepatocyte-specific Dyrk1a gene transfer rescues plasma apolipoprotein A-I levels and aortic Akt/GSK3 pathways in hyperhomocysteinemic mice.

Tlili A, Jacobs F, de Koning L, Mohamed S, Bui LC, Dairou J, Belin N, Ducros V, Dubois T, Paul JL, Delabar JM, De Geest B, Janel N.

Biochim Biophys Acta. 2013 Jun;1832(6):718-28. doi: 10.1016/j.bbadis.2013.02.008. Epub 2013 Feb 18.


Mice deficient in cystathionine beta synthase display increased Dyrk1A and SAHH activities in brain.

Planque C, Dairou J, Noll C, Bui LC, Ripoll C, Guedj F, Delabar JM, Janel N.

J Mol Neurosci. 2013 May;50(1):1-6. doi: 10.1007/s12031-012-9835-0. Epub 2012 Jun 15.


The aryl hydrocarbon receptor regulates focal adhesion sites through a non-genomic FAK/Src pathway.

Tomkiewicz C, Herry L, Bui LC, Métayer C, Bourdeloux M, Barouki R, Coumoul X.

Oncogene. 2013 Apr 4;32(14):1811-20. doi: 10.1038/onc.2012.197. Epub 2012 Jun 4.


Inflammatory pathway genes belong to major targets of persistent organic pollutants in adipose cells.

Kim MJ, Pelloux V, Guyot E, Tordjman J, Bui LC, Chevallier A, Forest C, Benelli C, Clément K, Barouki R.

Environ Health Perspect. 2012 Apr;120(4):508-14. doi: 10.1289/ehp.1104282. Epub 2012 Jan 19.


NOD mice contain an elevated frequency of iNKT17 cells that exacerbate diabetes.

Simoni Y, Gautron AS, Beaudoin L, Bui LC, Michel ML, Coumoul X, Eberl G, Leite-de-Moraes M, Lehuen A.

Eur J Immunol. 2011 Dec;41(12):3574-85. doi: 10.1002/eji.201141751. Epub 2011 Nov 10.


Induction of the Ras activator Son of Sevenless 1 by environmental pollutants mediates their effects on cellular proliferation.

Pierre S, Bats AS, Chevallier A, Bui LC, Ambolet-Camoit A, Garlatti M, Aggerbeck M, Barouki R, Coumoul X.

Biochem Pharmacol. 2011 Jan 15;81(2):304-13. doi: 10.1016/j.bcp.2010.10.003. Epub 2010 Oct 13.


2,3,7,8-tetrachlorodibenzo-p-dioxin counteracts the p53 response to a genotoxicant by upregulating expression of the metastasis marker agr2 in the hepatocarcinoma cell line HepG2.

Ambolet-Camoit A, Bui LC, Pierre S, Chevallier A, Marchand A, Coumoul X, Garlatti M, Andreau K, Barouki R, Aggerbeck M.

Toxicol Sci. 2010 Jun;115(2):501-12. doi: 10.1093/toxsci/kfq082. Epub 2010 Mar 18.


Nedd9/Hef1/Cas-L mediates the effects of environmental pollutants on cell migration and plasticity.

Bui LC, Tomkiewicz C, Chevallier A, Pierre S, Bats AS, Mota S, Raingeaud J, Pierre J, Diry M, Transy C, Garlatti M, Barouki R, Coumoul X.

Oncogene. 2009 Oct 15;28(41):3642-51. doi: 10.1038/onc.2009.224. Epub 2009 Aug 3.


Retrotransposon expression as a defining event of genome reprogramming in fertilized and cloned bovine embryos.

Bui LC, Evsikov AV, Khan DR, Archilla C, Peynot N, Hénaut A, Le Bourhis D, Vignon X, Renard JP, Duranthon V.

Reproduction. 2009 Aug;138(2):289-99. doi: 10.1530/REP-09-0042. Epub 2009 May 22.


Revealing the dynamics of gene expression during embryonic genome activation and first differentiation in the rabbit embryo with a dedicated array screening.

Léandri RD, Archilla C, Bui LC, Peynot N, Liu Z, Cabau C, Chastellier A, Renard JP, Duranthon V.

Physiol Genomics. 2009 Jan 8;36(2):98-113. doi: 10.1152/physiolgenomics.90310.2008. Epub 2008 Nov 11.


Genomic conservation of cattle microsatellite loci in wild gaur (Bos gaurus) and current genetic status of this species in Vietnam.

Nguyen TT, Genini S, Bui LC, Voegeli P, Stranzinger G, Renard JP, Maillard JC, Nguyen BX.

BMC Genet. 2007 Nov 6;8:77.


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