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Items: 18


Comment on: FDG PET-CT in pediatric Langerhans cell histiocytosis: Can all birds be killed with just one stone?

Buhtoiarov IN.

Pediatr Blood Cancer. 2020 May;67(5):e28214. doi: 10.1002/pbc.28214. Epub 2020 Feb 9. No abstract available.


Pediatric Lymphoma.

Buhtoiarov IN.

Pediatr Rev. 2017 Sep;38(9):410-423. doi: 10.1542/pir.2016-0152. Review. No abstract available.


Ab-IL2 fusion proteins mediate NK cell immune synapse formation by polarizing CD25 to the target cell-effector cell interface.

Gubbels JA, Gadbaw B, Buhtoiarov IN, Horibata S, Kapur AK, Patel D, Hank JA, Gillies SD, Sondel PM, Patankar MS, Connor J.

Cancer Immunol Immunother. 2011 Dec;60(12):1789-800. doi: 10.1007/s00262-011-1072-9. Epub 2011 Jul 27.


Differential internalization of hu14.18-IL2 immunocytokine by NK and tumor cell: impact on conjugation, cytotoxicity, and targeting.

Buhtoiarov IN, Neal ZC, Gan J, Buhtoiarova TN, Patankar MS, Gubbels JA, Hank JA, Yamane B, Rakhmilevich AL, Reisfeld RA, Gillies SD, Sondel PM.

J Leukoc Biol. 2011 Apr;89(4):625-38. doi: 10.1189/jlb.0710422. Epub 2011 Jan 19.


Enhanced T-cell-independent antitumor effect of cyclophosphamide combined with anti-CD40 mAb and CpG in mice.

Johnson EE, Buhtoiarov IN, Baldeshwiler MJ, Felder MA, Van Rooijen N, Sondel PM, Rakhmilevich AL.

J Immunother. 2011 Jan;34(1):76-84. doi: 10.1097/CJI.0b013e318200b28a.


Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages.

Buhtoiarov IN, Sondel PM, Wigginton JM, Buhtoiarova TN, Yanke EM, Mahvi DA, Rakhmilevich AL.

Immunology. 2011 Feb;132(2):226-39. doi: 10.1111/j.1365-2567.2010.03357.x. Epub 2010 Oct 13.


Radiofrequency ablation combined with KS-IL2 immunocytokine (EMD 273066) results in an enhanced antitumor effect against murine colon adenocarcinoma.

Johnson EE, Yamane BH, Buhtoiarov IN, Lum HD, Rakhmilevich AL, Mahvi DM, Gillies SD, Sondel PM.

Clin Cancer Res. 2009 Aug 1;15(15):4875-84. doi: 10.1158/1078-0432.CCR-09-0110. Epub 2009 Jul 28.


Tumoricidal effects of activated macrophages in a mouse model of chronic lymphocytic leukemia.

Wu QL, Buhtoiarov IN, Sondel PM, Rakhmilevich AL, Ranheim EA.

J Immunol. 2009 Jun 1;182(11):6771-8. doi: 10.4049/jimmunol.0801847.


Naive mouse macrophages become activated following recognition of L5178Y lymphoma cells via concurrent ligation of CD40, NKG2D, and CD18 molecules.

Buhtoiarov IN, Rakhmilevich AL, Lanier LL, Ranheim EA, Sondel PM.

J Immunol. 2009 Feb 15;182(4):1940-53. doi: 10.4049/jimmunol.0800443.


Intratumoral immunocytokine treatment results in enhanced antitumor effects.

Johnson EE, Lum HD, Rakhmilevich AL, Schmidt BE, Furlong M, Buhtoiarov IN, Hank JA, Raubitschek A, Colcher D, Reisfeld RA, Gillies SD, Sondel PM.

Cancer Immunol Immunother. 2008 Dec;57(12):1891-902. doi: 10.1007/s00262-008-0519-0. Epub 2008 Apr 26.


CD40 ligation in vivo can induce T cell independent antitumor effects even against immunogenic tumors.

Rakhmilevich AL, Buhtoiarov IN, Malkovsky M, Sondel PM.

Cancer Immunol Immunother. 2008 Aug;57(8):1151-60. doi: 10.1007/s00262-007-0447-4. Epub 2008 Jan 24.


Macrophages are essential for antitumour effects against weakly immunogenic murine tumours induced by class B CpG-oligodeoxynucleotides.

Buhtoiarov IN, Sondel PM, Eickhoff JC, Rakhmilevich AL.

Immunology. 2007 Mar;120(3):412-23. Epub 2006 Dec 8.


Tumoristatic effects of anti-CD40 mAb-activated macrophages involve nitric oxide and tumour necrosis factor-alpha.

Lum HD, Buhtoiarov IN, Schmidt BE, Berke G, Paulnock DM, Sondel PM, Rakhmilevich AL.

Immunology. 2006 Jun;118(2):261-70.


In vivo CD40 ligation can induce T-cell-independent antitumor effects that involve macrophages.

Lum HD, Buhtoiarov IN, Schmidt BE, Berke G, Paulnock DM, Sondel PM, Rakhmilevich AL.

J Leukoc Biol. 2006 Jun;79(6):1181-92. Epub 2006 Mar 24.


Synergistic activation of macrophages via CD40 and TLR9 results in T cell independent antitumor effects.

Buhtoiarov IN, Lum HD, Berke G, Sondel PM, Rakhmilevich AL.

J Immunol. 2006 Jan 1;176(1):309-18.


CD40 ligation activates murine macrophages via an IFN-gamma-dependent mechanism resulting in tumor cell destruction in vitro.

Buhtoiarov IN, Lum H, Berke G, Paulnock DM, Sondel PM, Rakhmilevich AL.

J Immunol. 2005 May 15;174(10):6013-22.


Enhanced activity of hu14.18-IL2 immunocytokine against murine NXS2 neuroblastoma when combined with interleukin 2 therapy.

Neal ZC, Yang JC, Rakhmilevich AL, Buhtoiarov IN, Lum HE, Imboden M, Hank JA, Lode HN, Reisfeld RA, Gillies SD, Sondel PM.

Clin Cancer Res. 2004 Jul 15;10(14):4839-47.


Pleasant memories: remembering immune protection while forgetting about graft-versus-host disease.

Sondel PM, Buhtoiarov IN, DeSantes K.

J Clin Invest. 2003 Jul;112(1):25-7. No abstract available.

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