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Comparison of Cerebral Palsy Severity Between 2 Eras of Antenatal Magnesium Use.

Stetson BT, Buhimschi CS, Kellert BA, Hay K, Buhimschi IA, Maitre NL.

JAMA Pediatr. 2018 Dec 3. doi: 10.1001/jamapediatrics.2018.3827. [Epub ahead of print] No abstract available.


Components of the antepartum, intrapartum, and postpartum exposome impact on distinct short-term adverse neonatal outcomes of premature infants: A prospective cohort study.

Nayeri UA, Buhimschi CS, Zhao G, Buhimschi IA, Bhandari V.

PLoS One. 2018 Dec 5;13(12):e0207298. doi: 10.1371/journal.pone.0207298. eCollection 2018.


Progestins Inhibit Tumor Necrosis Factor α-Induced Matrix Metalloproteinase 9 Activity via the Glucocorticoid Receptor in Primary Amnion Epithelial Cells.

Allen TK, Nazzal MN, Feng L, Buhimschi IA, Murtha AP.

Reprod Sci. 2018 Nov 19:1933719118811646. doi: 10.1177/1933719118811646. [Epub ahead of print]


Tenascin-x in Amniotic Fluid and Reproductive Tissues of Pregnancies Complicated by Infection and Preterm Prelabor Rupture of Membranes.

Rood KM, Buhimschi CS, Zhao G, Oliver EA, Summerfield T, Bahtiyar MO, Buhimschi IA.

Biol Reprod. 2018 Oct 2. doi: 10.1093/biolre/ioy216. [Epub ahead of print]


Human Placenta Expresses α2-Adrenergic Receptors and May Be Implicated in Pathogenesis of Preeclampsia and Fetal Growth Restriction.

Motawea HKB, Chotani MA, Ali M, Ackerman W, Zhao G, Ahmed AAE, Buhimschi CS, Buhimschi IA.

Am J Pathol. 2018 Dec;188(12):2774-2785. doi: 10.1016/j.ajpath.2018.08.011. Epub 2018 Sep 29.


Changes in Vasodilator-Stimulated Phosphoprotein Phosphorylation, Profilin-1, and Cofilin-1 in Accreta and Protection by DHA.

Ali M, Rogers LK, Heyob KM, Buhimschi CS, Buhimschi IA.

Reprod Sci. 2018 Aug 9:1933719118792095. doi: 10.1177/1933719118792095. [Epub ahead of print]


Skin Microbiota in Obese Women at Risk for Surgical Site Infection After Cesarean Delivery.

Rood KM, Buhimschi IA, Jurcisek JA, Summerfield TL, Zhao G, Ackerman WE, Wang W, Rumpf RW, Thung SF, Bakaletz LO, Buhimschi CS.

Sci Rep. 2018 Jun 8;8(1):8756. doi: 10.1038/s41598-018-27134-5.


Kinetics and mechanical stability of the fibril state control fibril formation time of polypeptide chains: A computational study.

Kouza M, Co NT, Li MS, Kmiecik S, Kolinski A, Kloczkowski A, Buhimschi IA.

J Chem Phys. 2018 Jun 7;148(21):215106. doi: 10.1063/1.5028575.


Serum and Urine Thioflavin-T-Enhanced Fluorescence in Severe Preeclampsia.

Millen KR, Buhimschi CS, Zhao G, Rood KM, Tabbah S, Buhimschi IA.

Hypertension. 2018 Jun;71(6):1185-1192. doi: 10.1161/HYPERTENSIONAHA.118.11034. Epub 2018 Apr 23.


Hepcidin, an Iron Regulatory Hormone of Innate Immunity, is Differentially Expressed in Premature Fetuses with Early-Onset Neonatal Sepsis.

Tabbah SM, Buhimschi CS, Rodewald-Millen K, Pierson CR, Bhandari V, Samuels P, Buhimschi IA.

Am J Perinatol. 2018 Jul;35(9):865-872. doi: 10.1055/s-0038-1626711. Epub 2018 Feb 2.


Extravillous trophoblast invasion in placenta accreta is associated with differential local expression of angiogenic and growth factors: a cross-sectional study.

Duzyj CM, Buhimschi IA, Laky CA, Cozzini G, Zhao G, Wehrum M, Buhimschi CS.

BJOG. 2018 Oct;125(11):1441-1448. doi: 10.1111/1471-0528.15176. Epub 2018 Apr 15.


Integrated microRNA and mRNA network analysis of the human myometrial transcriptome in the transition from quiescence to labor.

Ackerman WE 4th, Buhimschi IA, Brubaker D, Maxwell S, Rood KM, Chance MR, Jing H, Mesiano S, Buhimschi CS.

Biol Reprod. 2018 Jun 1;98(6):834-845. doi: 10.1093/biolre/ioy040.


Identification of haptoglobin switch-on status in archived placental specimens indicates antenatal exposure to inflammation and potential participation of the fetus in triggering preterm birth.

McCarthy ME, Buhimschi CS, Hardy JT, Dulay AT, Laky CA, Bahtyiar MO, Papanna R, Zhao G, Buhimschi IA.

Placenta. 2018 Feb;62:50-57. doi: 10.1016/j.placenta.2017.12.017. Epub 2017 Dec 24.


Preterm Birth and Gestational Length in Four Race-Nativity Groups, Including Somali Americans.

Oliver EA, Klebanoff M, Yossef-Salameh L, Oza-Frank R, Moosavinasab S, Reagan P, Muglia L, Buhimschi CS, Buhimschi IA.

Obstet Gynecol. 2018 Feb;131(2):281-289. doi: 10.1097/AOG.0000000000002427.


Oligomerization of FVFLM peptides and their ability to inhibit beta amyloid peptides aggregation: consideration as a possible model.

Kouza M, Banerji A, Kolinski A, Buhimschi IA, Kloczkowski A.

Phys Chem Chem Phys. 2017 Jan 25;19(4):2990-2999. doi: 10.1039/c6cp07145g.


Patterns of Empiric Antibiotic Administration for Presumed Early-Onset Neonatal Sepsis in Neonatal Intensive Care Units in the United States.

Oliver EA, Reagan PB, Slaughter JL, Buhimschi CS, Buhimschi IA.

Am J Perinatol. 2017 Jun;34(7):640-647. doi: 10.1055/s-0036-1596055. Epub 2016 Dec 6.


Calciprotein particles as potential etiologic agents of idiopathic preterm birth.

Shook LL, Buhimschi CS, Dulay AT, McCarthy ME, Hardy JT, Duzyj Buniak CM, Zhao G, Buhimschi IA.

Sci Transl Med. 2016 Nov 9;8(364):364ra154.


Limiting the Exposure of Select Fetuses to Intrauterine Infection/Inflammation Improves Short-Term Neonatal Outcomes in Preterm Premature Rupture of Membranes.

Archabald KL, Buhimschi IA, Bahtiyar MO, Dulay AT, Abdel-Razeq SS, Pettker CM, Lipkind HS, Hardy JT, McCarthy ME, Zhao G, Bhandari V, Buhimschi CS.

Fetal Diagn Ther. 2017;42(2):99-110. doi: 10.1159/000450997. Epub 2016 Oct 29.


H19 long noncoding RNA alters trophoblast cell migration and invasion by regulating TβR3 in placentae with fetal growth restriction.

Zuckerwise L, Li J, Lu L, Men Y, Geng T, Buhimschi CS, Buhimschi IA, Bukowski R, Guller S, Paidas M, Huang Y.

Oncotarget. 2016 Jun 21;7(25):38398-38407. doi: 10.18632/oncotarget.9534.


Comprehensive RNA profiling of villous trophoblast and decidua basalis in pregnancies complicated by preterm birth following intra-amniotic infection.

Ackerman WE 4th, Buhimschi IA, Eidem HR, Rinker DC, Rokas A, Rood K, Zhao G, Summerfield TL, Landon MB, Buhimschi CS.

Placenta. 2016 Aug;44:23-33. doi: 10.1016/j.placenta.2016.05.010. Epub 2016 May 30.


Evidence for participation of neutrophil gelatinase-associated lipocalin/matrix metalloproteinase-9 (NGAL•MMP-9) complex in the inflammatory response to infection in pregnancies complicated by preterm birth.

Rood KM, Buhimschi IA, Rodewald Millen K, Bahtiyar MO, Thung S, Summerfield T, Zhao G, Ackerman W 4th, Shellhaas C, Samuels P, Buhimschi CS.

Am J Reprod Immunol. 2016 Aug;76(2):108-17. doi: 10.1111/aji.12523. Epub 2016 Jun 1.


Comparing human and macaque placental transcriptomes to disentangle preterm birth pathology from gestational age effects.

Eidem HR, Rinker DC, Ackerman WE 4th, Buhimschi IA, Buhimschi CS, Dunn-Fletcher C, Kallapur SG, Pavličev M, Muglia LJ, Abbot P, Rokas A.

Placenta. 2016 May;41:74-82. doi: 10.1016/j.placenta.2016.03.006. Epub 2016 Mar 12.


Imbalance of Amniotic Fluid Activin-A and Follistatin in Intraamniotic Infection, Inflammation, and Preterm Birth.

Hardy JT, Buhimschi IA, McCarthy ME, Zhao G, Laky CA, Shook LL, Buhimschi CS.

J Clin Endocrinol Metab. 2016 Jul;101(7):2785-93. doi: 10.1210/jc.2015-4147. Epub 2016 May 9.


High Mobility Group-Box 1 (HMGB1) levels are increased in amniotic fluid of women with intra-amniotic inflammation-determined preterm birth, and the source may be the damaged fetal membranes.

Baumbusch MA, Buhimschi CS, Oliver EA, Zhao G, Thung S, Rood K, Buhimschi IA.

Cytokine. 2016 May;81:82-7. doi: 10.1016/j.cyto.2016.02.013. Epub 2016 Mar 5.


Development and Validation of an Algorithm to Determine Spontaneous versus Provider-Initiated Preterm Birth in US Vital Records.

Klebanoff MA, Yossef-Salameh L, Latimer C, Oza-Frank R, Kachoria R, Reagan PB, Oliver EA, Buhimschi CS, Buhimschi IA.

Paediatr Perinat Epidemiol. 2016 Mar;30(2):134-40. doi: 10.1111/ppe.12267.


Evaluation and Management of Women and Newborns With a Maternal Diagnosis of Chorioamnionitis: Summary of a Workshop.

Higgins RD, Saade G, Polin RA, Grobman WA, Buhimschi IA, Watterberg K, Silver RM, Raju TN; Chorioamnionitis Workshop Participants.

Obstet Gynecol. 2016 Mar;127(3):426-36. doi: 10.1097/AOG.0000000000001246.


Mechanisms of chorioamnionitis-associated preterm birth: interleukin-1β inhibits progesterone receptor expression in decidual cells.

Guzeloglu-Kayisli O, Kayisli UA, Semerci N, Basar M, Buchwalder LF, Buhimschi CS, Buhimschi IA, Arcuri F, Larsen K, Huang JS, Schatz F, Lockwood CJ.

J Pathol. 2015 Dec;237(4):423-34. doi: 10.1002/path.4589. Epub 2015 Aug 19.


Smartphone-based diagnostic for preeclampsia: an mHealth solution for administering the Congo Red Dot (CRD) test in settings with limited resources.

Jonas SM, Deserno TM, Buhimschi CS, Makin J, Choma MA, Buhimschi IA.

J Am Med Inform Assoc. 2016 Jan;23(1):166-73. doi: 10.1093/jamia/ocv015. Epub 2015 May 29.


Histologic changes of the fetal membranes after fetoscopic laser surgery for twin-twin transfusion syndrome.

Papanna R, Mann LK, Moise KJ Jr, Kyriakides T, Johnson A, Garcia E, Buhimschi CS, Buhimschi IA.

Pediatr Res. 2015 Sep;78(3):247-55. doi: 10.1038/pr.2015.105. Epub 2015 May 28.


Compartmentalization of acute phase reactants Interleukin-6, C-Reactive Protein and Procalcitonin as biomarkers of intra-amniotic infection and chorioamnionitis.

Dulay AT, Buhimschi IA, Zhao G, Bahtiyar MO, Thung SF, Cackovic M, Buhimschi CS.

Cytokine. 2015 Dec;76(2):236-243. doi: 10.1016/j.cyto.2015.04.014. Epub 2015 May 6.


The invasive phenotype of placenta accreta extravillous trophoblasts associates with loss of E-cadherin.

Duzyj CM, Buhimschi IA, Motawea H, Laky CA, Cozzini G, Zhao G, Funai EF, Buhimschi CS.

Placenta. 2015 Jun;36(6):645-51. doi: 10.1016/j.placenta.2015.04.001. Epub 2015 Apr 14.


The Effect of Progestins on Tumor Necrosis Factor α-Induced Matrix Metalloproteinase-9 Activity and Gene Expression in Human Primary Amnion and Chorion Cells In Vitro.

Allen TK, Feng L, Nazzal M, Grotegut CA, Buhimschi IA, Murtha AP.

Anesth Analg. 2015 May;120(5):1085-94. doi: 10.1213/ANE.0000000000000708.


Hyperferritinemia and markers of inflammation and oxidative stress in the cord blood of HIV-exposed, uninfected (HEU) infants.

Selvam A, Buhimschi IA, Makin JD, Pattinson RC, Anderson R, Forsyth BW.

HIV Med. 2015 Jul;16(6):375-80. doi: 10.1111/hiv.12214. Epub 2015 Feb 27.


Amniotic Fluid Soluble Myeloid Differentiation-2 (sMD-2) as Regulator of Intra-amniotic Inflammation in Infection-induced Preterm Birth.

Dulay AT, Buhimschi CS, Zhao G, Oliver EA, Abdel-Razeq SS, Shook LL, Bahtiyar MO, Buhimschi IA.

Am J Reprod Immunol. 2015 Jun;73(6):507-21. doi: 10.1111/aji.12362. Epub 2015 Jan 21.


Protein misfolding, congophilia, oligomerization, and defective amyloid processing in preeclampsia.

Buhimschi IA, Nayeri UA, Zhao G, Shook LL, Pensalfini A, Funai EF, Bernstein IM, Glabe CG, Buhimschi CS.

Sci Transl Med. 2014 Jul 16;6(245):245ra92. doi: 10.1126/scitranslmed.3008808.


Response to letter regarding article, "dysregulation of hydrogen sulfide (H2S) producing enzyme cystathionine γ-lyase (CSE) contributes to maternal hypertension and placental abnormalities in preeclampsia".

Wang K, Ahmad S, Cai M, Rennie J, Fujisawa T, Crispi F, Baily J, Miller MR, Cudmore M, Hadoke PW, Wang R, Gratacós E, Buhimschi IA, Buhimschi CS, Ahmed A.

Circulation. 2014 Jun 3;129(22):e517-8. doi: 10.1161/CIRCULATIONAHA.114.010273. No abstract available.


Antenatal corticosteroids impact the inflammatory rather than the antiangiogenic profile of women with preeclampsia.

Nayeri UA, Buhimschi IA, Laky CA, Cross SN, Duzyj CM, Ramma W, Sibai BM, Funai EF, Ahmed A, Buhimschi CS.

Hypertension. 2014 Jun;63(6):1285-92. doi: 10.1161/HYPERTENSIONAHA.114.03173. Epub 2014 Mar 24.


Risk factors associated with preterm delivery after fetoscopic laser ablation for twin-twin transfusion syndrome.

Papanna R, Block-Abraham D, Mann LK, Buhimschi IA, Bebbington M, Garcia E, Kahlek N, Harman C, Johnson A, Baschat A, Moise KJ Jr.

Ultrasound Obstet Gynecol. 2014 Jan;43(1):48-53. doi: 10.1002/uog.13206.


Dysregulation of hydrogen sulfide producing enzyme cystathionine γ-lyase contributes to maternal hypertension and placental abnormalities in preeclampsia.

Wang K, Ahmad S, Cai M, Rennie J, Fujisawa T, Crispi F, Baily J, Miller MR, Cudmore M, Hadoke PW, Wang R, Gratacós E, Buhimschi IA, Buhimschi CS, Ahmed A.

Circulation. 2013 Jun 25;127(25):2514-22. doi: 10.1161/CIRCULATIONAHA.113.001631. Epub 2013 May 23.


Advances in medical diagnosis of intra-amniotic infection.

Buhimschi IA, Nayeri UA, Laky CA, Razeq SA, Dulay AT, Buhimschi CS.

Expert Opin Med Diagn. 2013 Jan;7(1):5-16. doi: 10.1517/17530059.2012.709232. Epub 2012 Aug 17. Review.


Decreased levels of folate receptor-β and reduced numbers of fetal macrophages (Hofbauer cells) in placentas from pregnancies with severe pre-eclampsia.

Tang Z, Buhimschi IA, Buhimschi CS, Tadesse S, Norwitz E, Niven-Fairchild T, Huang ST, Guller S.

Am J Reprod Immunol. 2013 Aug;70(2):104-15. doi: 10.1111/aji.12112. Epub 2013 Mar 11.


Comparative microbial analysis of paired amniotic fluid and cord blood from pregnancies complicated by preterm birth and early-onset neonatal sepsis.

Wang X, Buhimschi CS, Temoin S, Bhandari V, Han YW, Buhimschi IA.

PLoS One. 2013;8(2):e56131. doi: 10.1371/journal.pone.0056131. Epub 2013 Feb 20.


Glucocorticoids enhance CD163 expression in placental Hofbauer cells.

Tang Z, Niven-Fairchild T, Tadesse S, Norwitz ER, Buhimschi CS, Buhimschi IA, Guller S.

Endocrinology. 2013 Jan;154(1):471-82. doi: 10.1210/en.2012-1575. Epub 2012 Nov 9.


Comparative analysis of 2-D versus 3-D ultrasound estimation of the fetal adrenal gland volume and prediction of preterm birth.

Turan OM, Turan S, Buhimschi IA, Funai EF, Campbell KH, Bahtiyar OM, Harman CR, Copel JA, Baschat AA, Buhimschi CS.

Am J Perinatol. 2012 Oct;29(9):673-80. doi: 10.1055/s-0032-1314887. Epub 2012 May 29.


The elevation in circulating anti-angiogenic factors is independent of markers of neutrophil activation in preeclampsia.

Ramma W, Buhimschi IA, Zhao G, Dulay AT, Nayeri UA, Buhimschi CS, Ahmed A.

Angiogenesis. 2012 Sep;15(3):333-40. doi: 10.1007/s10456-012-9261-5. Epub 2012 Mar 8.


Proteomics/diagnosis of chorioamnionitis and of relationships with the fetal exposome.

Buhimschi IA, Buhimschi CS.

Semin Fetal Neonatal Med. 2012 Feb;17(1):36-45. doi: 10.1016/j.siny.2011.10.002. Epub 2011 Nov 21. Review.


Heparin elevates circulating soluble fms-like tyrosine kinase-1 immunoreactivity in pregnant women receiving anticoagulation therapy.

Rosenberg VA, Buhimschi IA, Lockwood CJ, Paidas MJ, Dulay AT, Ramma W, Abdel-Razeq SS, Zhao G, Ahmad S, Ahmed A, Buhimschi CS.

Circulation. 2011 Dec 6;124(23):2543-53. doi: 10.1161/CIRCULATIONAHA.111.046821. Epub 2011 Nov 14.


Proteomics mapping of cord blood identifies haptoglobin "switch-on" pattern as biomarker of early-onset neonatal sepsis in preterm newborns.

Buhimschi CS, Bhandari V, Dulay AT, Nayeri UA, Abdel-Razeq SS, Pettker CM, Thung S, Zhao G, Han YW, Bizzarro M, Buhimschi IA.

PLoS One. 2011;6(10):e26111. doi: 10.1371/journal.pone.0026111. Epub 2011 Oct 10.


Modulation of amniotic fluid activin-a and inhibin-a in women with preterm premature rupture of the membranes and infection-induced preterm birth.

Rosenberg VA, Buhimschi IA, Dulay AT, Abdel-Razeq SS, Oliver EA, Duzyj CM, Lipkind H, Pettker CM, Buhimschi CS.

Am J Reprod Immunol. 2012 Feb;67(2):122-31. doi: 10.1111/j.1600-0897.2011.01074.x. Epub 2011 Oct 13.

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