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Items: 24

1.

NF-κB activation mediates LPS-or zymosan-induced hypotension and inflammation reversed by BAY61-3606, a selective Syk inhibitor, in rat models of septic and non-septic shock.

Sahan-Firat S, Temiz-Resitoglu M, Guden DS, Senol SP, Sari AN, Cil M, Unsal D, Korkmaz B, Tunctan B, Malik KU, Buharalioglu CK.

Clin Exp Pharmacol Physiol. 2019 Feb;46(2):173-182. doi: 10.1111/1440-1681.13045.

PMID:
30347478
2.

Pregnancy outcomes after maternal betahistine exposure: A case series.

Buharalioglu CK, Acar S, Erol-Coskun H, Küçüksolak G, Karadas B, Kaya-Temiz T, Kaplan YC.

Reprod Toxicol. 2018 Aug;79:79-83. doi: 10.1016/j.reprotox.2018.06.004. Epub 2018 Jun 13.

PMID:
29908288
3.

The role of Syk/IĸB-α/NF-ĸB pathway activation in the reversal effect of BAY 61-3606, a selective Syk inhibitor, on hypotension and inflammation in a rat model of zymosan-induced non-septic shock.

Unsal D, Kacan M, Temiz-Resitoglu M, Guden DS, Korkmaz B, Sari AN, Buharalioglu CK, Yildirim-Yaroglu H, Tamer-Gumus L, Tunctan B, Malik KU, Sahan-Firat S.

Clin Exp Pharmacol Physiol. 2018 Feb;45(2):155-165. doi: 10.1111/1440-1681.12864. Epub 2017 Nov 28.

PMID:
28949404
4.

Activation of mTOR/IκB-α/NF-κB pathway contributes to LPS-induced hypotension and inflammation in rats.

Temiz-Resitoglu M, Kucukkavruk SP, Guden DS, Cecen P, Sari AN, Tunctan B, Gorur A, Tamer-Gumus L, Buharalioglu CK, Malik KU, Sahan-Firat S.

Eur J Pharmacol. 2017 May 5;802:7-19. doi: 10.1016/j.ejphar.2017.02.034. Epub 2017 Feb 20.

PMID:
28228357
5.

Effects of 5,14-HEDGE, a 20-HETE mimetic, on lipopolysaccharide-induced changes in MyD88/TAK1/IKKβ/IκB-α/NF-κB pathway and circulating miR-150, miR-223, and miR-297 levels in a rat model of septic shock.

Sari AN, Korkmaz B, Serin MS, Kacan M, Unsal D, Buharalioglu CK, Sahan Firat S, Manthati VL, Falck JR, Malik KU, Tunctan B.

Inflamm Res. 2014 Sep;63(9):741-56. doi: 10.1007/s00011-014-0747-z. Epub 2014 Jun 12.

6.

Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91(phox) to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock.

Tunctan B, Korkmaz B, Sari AN, Kacan M, Unsal D, Serin MS, Buharalioglu CK, Sahan-Firat S, Cuez T, Schunck WH, Manthati VL, Falck JR, Malik KU.

Nitric Oxide. 2013 Sep 1;33:18-41. doi: 10.1016/j.niox.2013.05.001. Epub 2013 May 14.

7.

5,14-HEDGE, a 20-HETE mimetic, reverses hypotension and improves survival in a rodent model of septic shock: contribution of soluble epoxide hydrolase, CYP2C23, MEK1/ERK1/2/IKKβ/IκB-α/NF-κB pathway, and proinflammatory cytokine formation.

Tunctan B, Korkmaz B, Sari AN, Kacan M, Unsal D, Serin MS, Buharalioglu CK, Sahan-Firat S, Cuez T, Schunck WH, Falck JR, Malik KU.

Prostaglandins Other Lipid Mediat. 2013 Apr-May;102-103:31-41. doi: 10.1016/j.prostaglandins.2013.01.005. Epub 2013 Feb 27.

8.

Contribution of MEK1/ERK1/2/iNOS pathway to oxidative stress and decreased caspase-3 activity in endotoxemic rats.

Korkmaz B, Cuez T, Buharalioglu CK, Demiryurek AT, Sahan-Firat S, Sari AN, Tunctan B.

Antiinflamm Antiallergy Agents Med Chem. 2012;11(3):243-52.

PMID:
23189948
9.

Increased production of nitric oxide mediates selective organ-specific effects of endotoxin on oxidative stress.

Sahan-Firat S, Canacankatan N, Korkmaz B, Yildirim H, Tamer L, Buharalioglu CK, Sari AN, Kacan M, Unsal D, Tunctan B.

Antiinflamm Antiallergy Agents Med Chem. 2012;11(2):161-72.

PMID:
23173576
10.

A novel treatment strategy for sepsis and septic shock based on the interactions between prostanoids, nitric oxide, and 20-hydroxyeicosatetraenoic acid.

Tunctan B, Korkmaz B, Sari AN, Kacan M, Unsal D, Serin MS, Buharalioglu CK, Sahan-Firat S, Schunck WH, Falck JR, Malik KU.

Antiinflamm Antiallergy Agents Med Chem. 2012;11(2):121-50. Review.

PMID:
23013331
11.

NS-398 reverses hypotension in endotoxemic rats: contribution of eicosanoids, NO, and peroxynitrite.

Tunctan B, Sari AN, Kacan M, Unsal D, Buharalioglu CK, Sahan-Firat S, Korkmaz B, Falck JR, Malik KU.

Prostaglandins Other Lipid Mediat. 2013 Jul-Aug;104-105:93-108. doi: 10.1016/j.prostaglandins.2012.08.007. Epub 2012 Sep 5.

12.

Angiotensin II-induced process of angiogenesis is mediated by spleen tyrosine kinase via VEGF receptor-1 phosphorylation.

Buharalioglu CK, Song CY, Yaghini FA, Ghafoor HU, Motiwala M, Adris T, Estes AM, Malik KU.

Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H1043-55. doi: 10.1152/ajpheart.01018.2010. Epub 2011 Jun 3.

13.

Piroxicam reverses endotoxin-induced hypotension in rats: contribution of vasoactive eicosanoids and nitric oxide.

Buharalioglu CK, Korkmaz B, Cuez T, Sahan-Firat S, Sari AN, Malik KU, Tunctan B.

Basic Clin Pharmacol Toxicol. 2011 Sep;109(3):186-94. doi: 10.1111/j.1742-7843.2011.00708.x. Epub 2011 May 6.

14.

A synthetic analogue of 20-HETE, 5,14-HEDGE, reverses endotoxin-induced hypotension via increased 20-HETE levels associated with decreased iNOS protein expression and vasodilator prostanoid production in rats.

Cuez T, Korkmaz B, Buharalioglu CK, Sahan-Firat S, Falck J, Malik KU, Tunctan B.

Basic Clin Pharmacol Toxicol. 2010 May;106(5):378-88. doi: 10.1111/j.1742-7843.2009.00501.x. Epub 2009 Dec 7.

15.

Angiotensin II-induced migration of vascular smooth muscle cells is mediated by p38 mitogen-activated protein kinase-activated c-Src through spleen tyrosine kinase and epidermal growth factor receptor transactivation.

Mugabe BE, Yaghini FA, Song CY, Buharalioglu CK, Waters CM, Malik KU.

J Pharmacol Exp Ther. 2010 Jan;332(1):116-24. doi: 10.1124/jpet.109.157552. Epub 2009 Oct 1. Erratum in: J Pharmacol Exp Ther. 2010 Nov;335(2):516-7.

16.

A 20-hydroxyeicosatetraenoic acid agonist, N-[20-hydroxyeicosa-5(Z),14(Z)-dienoyl]glycine, opposes the fall in blood pressure and vascular reactivity in endotoxin-treated rats.

Tunctan B, Korkmaz B, Buharalioglu CK, Firat SS, Anjaiah S, Falck J, Roman RJ, Malik KU.

Shock. 2008 Sep;30(3):329-35. doi: 10.1097/SHK.0b013e31816471c6.

17.

The effects of bumetanide on human umbilical artery contractions.

Dayioglu E, Buharalioglu CK, Saracoglu F, Akar F.

Reprod Sci. 2007 Apr;14(3):246-52.

PMID:
17636238
18.

Inhibition of extracellular signal-regulated kinase (ERK1/2) activity reverses endotoxin-induced hypotension via decreased nitric oxide production in rats.

Tunctan B, Korkmaz B, Dogruer ZN, Tamer L, Atik U, Buharalioglu CK.

Pharmacol Res. 2007 Jul;56(1):56-64. Epub 2007 Apr 13.

PMID:
17524662
19.

Extracellular signal-regulated kinase (ERK1/2) contributes to endotoxin-induced hyporeactivity via nitric oxide and prostacyclin production in rat aorta.

Korkmaz B, Ozveren E, Buharalioglu CK, Tunctan B.

Pharmacology. 2006;78(3):123-8. Epub 2006 Sep 27.

PMID:
17008773
20.

Involvement of calcium/calmodulin-dependent protein kinase II to endotoxin-induced vascular hyporeactivity in rat superior mesenteric artery.

Ozveren E, Korkmaz B, Buharalioglu CK, Tunctan B.

Pharmacol Res. 2006 Sep;54(3):208-18. Epub 2006 May 12.

PMID:
16777431
21.

Nitric oxide reverses endotoxin-induced inflammatory hyperalgesia via inhibition of prostacyclin production in mice.

Tunctan B, Ozveren E, Korkmaz B, Buharalioglu CK, Tamer L, Degirmenci U, Atik U.

Pharmacol Res. 2006 Feb;53(2):177-92. Epub 2005 Nov 28.

PMID:
16310374
22.
23.

Studies on the vascular effects of the fractions and phenolic compounds isolated from Viscum album ssp. album.

Deliorman D, Caliş I, Ergun F, Doğan BS, Buharalioğlu CK, Kanzik I.

J Ethnopharmacol. 2000 Sep;72(1-2):323-9.

PMID:
10967490
24.

Protective effect of cromakalim and diazoxide, and proulcerogenic effect of glibenclamide on indomethacin-induced gastric injury.

Akar F, Uydeş-Doğan BS, Buharalioğlu CK, Abban G, Heinemann A, Holzer P, Van de Voorde J.

Eur J Pharmacol. 1999 Jun 25;374(3):461-70.

PMID:
10422791

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