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Items: 1 to 50 of 63

1.

Single-Pass Albumin Dialysis in the Treatment of Children with Liver Failure.

Holle J, Gratopp A, Balmer S, Varnholt V, Henning S, Bufler P, Müller D, Rosenfeld L.

Blood Purif. 2019 Sep 17:1-8. doi: 10.1159/000502938. [Epub ahead of print]

PMID:
31527371
2.

Caplacizumab for relapsing thrombotic thrombocytopenic purpura.

Kaczmarek V, Holle J, Astudillo R, Kempf C, Bufler P, Müller D.

Pediatr Nephrol. 2019 Sep;34(9):1625-1628. doi: 10.1007/s00467-019-04281-z. Epub 2019 Jun 8.

PMID:
31177334
3.

Role for nuclear interleukin-37 in the suppression of innate immunity.

Li S, Amo-Aparicio J, Neff CP, Tengesdal IW, Azam T, Palmer BE, López-Vales R, Bufler P, Dinarello CA.

Proc Natl Acad Sci U S A. 2019 Feb 21. pii: 201821111. doi: 10.1073/pnas.1821111116. [Epub ahead of print]

4.

Biologika in der Therapie kindlicher chronisch-entzündlicher Darmerkrankungen.

Bufler P.

Drug Res (Stuttg). 2018 Nov;68(S 01):S15. doi: 10.1055/a-0733-0827. Epub 2018 Nov 19. German. No abstract available.

PMID:
30453367
5.

Tomoelastography for the Evaluation of Pediatric Nonalcoholic Fatty Liver Disease.

Hudert CA, Tzschätzsch H, Rudolph B, Bläker H, Loddenkemper C, Müller HP, Henning S, Bufler P, Hamm B, Braun J, Holzhütter HG, Wiegand S, Sack I, Guo J.

Invest Radiol. 2019 Apr;54(4):198-203. doi: 10.1097/RLI.0000000000000529.

PMID:
30444796
6.

Genetic determinants of steatosis and fibrosis progression in paediatric non-alcoholic fatty liver disease.

Hudert CA, Selinski S, Rudolph B, Bläker H, Loddenkemper C, Thielhorn R, Berndt N, Golka K, Cadenas C, Reinders J, Henning S, Bufler P, Jansen PLM, Holzhütter HG, Meierhofer D, Hengstler JG, Wiegand S.

Liver Int. 2019 Mar;39(3):540-556. doi: 10.1111/liv.14006. Epub 2018 Dec 21.

PMID:
30444569
7.

Intestinal Inflammation and Dysregulated Immunity in Patients With Inherited Caspase-8 Deficiency.

Lehle AS, Farin HF, Marquardt B, Michels BE, Magg T, Li Y, Liu Y, Ghalandary M, Lammens K, Hollizeck S, Rohlfs M, Hauck F, Conca R, Walz C, Weiss B, Lev A, Simon AJ, Groß O, Gaidt MM, Hornung V, Clevers H, Yazbeck N, Hanna-Wakim R, Shouval DS, Warner N, Somech R, Muise AM, Snapper SB, Bufler P, Koletzko S, Klein C, Kotlarz D.

Gastroenterology. 2019 Jan;156(1):275-278. doi: 10.1053/j.gastro.2018.09.041. Epub 2018 Sep 26. No abstract available.

PMID:
30267714
8.

Human TGF-β1 deficiency causes severe inflammatory bowel disease and encephalopathy.

Kotlarz D, Marquardt B, Barøy T, Lee WS, Konnikova L, Hollizeck S, Magg T, Lehle AS, Walz C, Borggraefe I, Hauck F, Bufler P, Conca R, Wall SM, Schumacher EM, Misceo D, Frengen E, Bentsen BS, Uhlig HH, Hopfner KP, Muise AM, Snapper SB, Strømme P, Klein C.

Nat Genet. 2018 Mar;50(3):344-348. doi: 10.1038/s41588-018-0063-6. Epub 2018 Feb 26.

9.

Hyperadiponectinemia During Infliximab Induction Therapy in Pediatric Crohn Disease.

Frivolt K, Schwerd T, Schatz SB, Freudenberg F, Prell C, Werkstetter KJ, Bufler P, Koletzko S.

J Pediatr Gastroenterol Nutr. 2018 Jun;66(6):915-919. doi: 10.1097/MPG.0000000000001876.

PMID:
29287006
10.

Ethanol-mediated suppression of IL-37 licenses alcoholic liver disease.

Grabherr F, Grander C, Adolph TE, Wieser V, Mayr L, Enrich B, Macheiner S, Sangineto M, Reiter A, Viveiros A, Zoller H, Bufler P, Moschen AR, Dinarello CA, Tilg H.

Liver Int. 2018 Jun;38(6):1095-1101. doi: 10.1111/liv.13642. Epub 2017 Dec 16.

PMID:
29193575
11.

[Abdominal pain in children: Rational diagnostics in the outpatient department].

Schwerd T, Bufler P.

MMW Fortschr Med. 2017 Aug;159(14):60-66. doi: 10.1007/s15006-017-9952-3. Review. German. No abstract available.

PMID:
28905311
12.

IL-37 Causes Excessive Inflammation and Tissue Damage in Murine Pneumococcal Pneumonia.

Schauer AE, Klassert TE, von Lachner C, Riebold D, Schneeweiß A, Stock M, Müller MM, Hammerschmidt S, Bufler P, Seifert U, Dietert K, Dinarello CA, Nold MF, Gruber AD, Nold-Petry CA, Slevogt H.

J Innate Immun. 2017;9(4):403-418. doi: 10.1159/000469661. Epub 2017 Jun 10.

13.

Increase of Intra-abdominal Adipose Tissue in Pediatric Crohn Disease.

Frivolt K, Hetterich H, Schwerd T, Hajji MS, Bufler P, Coppenrath E, Koletzko S.

J Pediatr Gastroenterol Nutr. 2017 Dec;65(6):633-638. doi: 10.1097/MPG.0000000000001593.

PMID:
28362691
14.

Suppression of innate inflammation and immunity by interleukin-37.

Dinarello CA, Nold-Petry C, Nold M, Fujita M, Li S, Kim S, Bufler P.

Eur J Immunol. 2016 May;46(5):1067-81. doi: 10.1002/eji.201545828. Review.

15.

Exclusive enteral nutrition in active pediatric Crohn disease: Effects on intestinal microbiota and immune regulation.

Schwerd T, Frivolt K, Clavel T, Lagkouvardos I, Katona G, Mayr D, Uhlig HH, Haller D, Koletzko S, Bufler P.

J Allergy Clin Immunol. 2016 Aug;138(2):592-6. doi: 10.1016/j.jaci.2015.12.1331. Epub 2016 Mar 15. No abstract available.

PMID:
26987574
16.

Beneficial effects of IL-37 after spinal cord injury in mice.

Coll-Miró M, Francos-Quijorna I, Santos-Nogueira E, Torres-Espin A, Bufler P, Dinarello CA, López-Vales R.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1411-6. doi: 10.1073/pnas.1523212113. Epub 2016 Jan 19.

17.

English language version of the S3-consensus guidelines on chronic pancreatitis: Definition, aetiology, diagnostic examinations, medical, endoscopic and surgical management of chronic pancreatitis.

Hoffmeister A, Mayerle J, Beglinger C, Büchler MW, Bufler P, Dathe K, Fölsch UR, Friess H, Izbicki J, Kahl S, Klar E, Keller J, Knoefel WT, Layer P, Loehr M, Meier R, Riemann JF, Rünzi M, Schmid RM, Schreyer A, Tribl B, Werner J, Witt H, Mössner J, Lerch MM; members of the guideline committee.

Z Gastroenterol. 2015 Dec;53(12):1447-95. doi: 10.1055/s-0041-107379. Epub 2015 Dec 14.

18.

Diagnostic and Treatment Options for Severe IBD in Female X-CGD Carriers with Non-random X-inactivation.

Hauck F, Koletzko S, Walz C, von Bernuth H, Klenk A, Schmid I, Belohradsky BH, Klein C, Bufler P, Albert MH.

J Crohns Colitis. 2016 Jan;10(1):112-5. doi: 10.1093/ecco-jcc/jjv186. Epub 2015 Oct 13.

PMID:
26464403
19.

IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction.

Nold-Petry CA, Lo CY, Rudloff I, Elgass KD, Li S, Gantier MP, Lotz-Havla AS, Gersting SW, Cho SX, Lao JC, Ellisdon AM, Rotter B, Azam T, Mangan NE, Rossello FJ, Whisstock JC, Bufler P, Garlanda C, Mantovani A, Dinarello CA, Nold MF.

Nat Immunol. 2015 Apr;16(4):354-65. doi: 10.1038/ni.3103. Epub 2015 Mar 2.

PMID:
25729923
20.

Diagnostic performance of three serologic tests in childhood celiac disease.

Bufler P, Heilig G, Ossiander G, Freudenberg F, Grote V, Koletzko S.

Z Gastroenterol. 2015 Feb;53(2):108-14. doi: 10.1055/s-0034-1385704. Epub 2015 Feb 10.

PMID:
25668712
21.

Corrigendum: IL-37 protects against obesity-induced inflammation and insulin resistance.

Ballak DB, van Diepen JA, Moschen AR, Jansen HJ, Hijmans A, Groenhof GJ, Leenders F, Bufler P, Boekschoten MV, Müller M, Kersten S, Li S, Kim S, Eini H, Lewis EC, Joosten LA, Tilg H, Netea MG, Tack CJ, Dinarello CA, Stienstra R.

Nat Commun. 2015 Jan 12;6:6039. doi: 10.1038/ncomms7039. No abstract available.

PMID:
25580956
22.

Suppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cells.

Luo Y, Cai X, Liu S, Wang S, Nold-Petry CA, Nold MF, Bufler P, Norris D, Dinarello CA, Fujita M.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):15178-83. doi: 10.1073/pnas.1416714111. Epub 2014 Oct 7.

23.

IL-37 protects against obesity-induced inflammation and insulin resistance.

Ballak DB, van Diepen JA, Moschen AR, Jansen HJ, Hijmans A, Groenhof GJ, Leenders F, Bufler P, Boekschoten MV, Müller M, Kersten S, Li S, Kim S, Eini H, Lewis EC, Joosten LA, Tilg H, Netea MG, Tack CJ, Dinarello CA, Stienstra R.

Nat Commun. 2014 Sep 3;5:4711. doi: 10.1038/ncomms5711. Erratum in: Nat Commun. 2015;6:6039.

PMID:
25182023
24.

Repeated exclusive enteral nutrition in the treatment of paediatric Crohn's disease: predictors of efficacy and outcome.

Frivolt K, Schwerd T, Werkstetter KJ, Schwarzer A, Schatz SB, Bufler P, Koletzko S.

Aliment Pharmacol Ther. 2014 Jun;39(12):1398-407. doi: 10.1111/apt.12770. Epub 2014 Apr 30.

25.

Intestinal expression of the anti-inflammatory interleukin-1 homologue IL-37 in pediatric inflammatory bowel disease.

Weidlich S, Bulau AM, Schwerd T, Althans J, Kappler R, Koletzko S, Mayr D, Bufler P.

J Pediatr Gastroenterol Nutr. 2014 Aug;59(2):e18-26. doi: 10.1097/MPG.0000000000000387.

PMID:
24732025
26.

Beneficial IFN-α treatment of tumorous herpes simplex blepharoconjunctivitis in dedicator of cytokinesis 8 deficiency.

Papan C, Hagl B, Heinz V, Albert MH, Ehrt O, Sawalle-Belohradsky J, Neumann J, Ries M, Bufler P, Wollenberg A, Renner ED.

J Allergy Clin Immunol. 2014 May;133(5):1456-8. doi: 10.1016/j.jaci.2014.02.008. Epub 2014 Apr 1. No abstract available.

PMID:
24698314
27.

Very early onset inflammatory bowel disease associated with aberrant trafficking of IL-10R1 and cure by T cell replete haploidentical bone marrow transplantation.

Murugan D, Albert MH, Langemeier J, Bohne J, Puchalka J, Järvinen PM, Hauck F, Klenk AK, Prell C, Schatz S, Diestelhorst J, Sciskala B, Kohistani N, Belohradsky BH, Müller S, Kirchner T, Walter MR, Bufler P, Muise AM, Snapper SB, Koletzko S, Klein C, Kotlarz D.

J Clin Immunol. 2014 Apr;34(3):331-9. doi: 10.1007/s10875-014-9992-8. Epub 2014 Feb 12.

PMID:
24519095
28.

Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses.

Bulau AM, Nold MF, Li S, Nold-Petry CA, Fink M, Mansell A, Schwerd T, Hong J, Rubartelli A, Dinarello CA, Bufler P.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2650-5. doi: 10.1073/pnas.1324140111. Epub 2014 Jan 30.

29.

Interleukin-37.

Dinarello CA, Bufler P.

Semin Immunol. 2013 Dec 15;25(6):466-8. doi: 10.1016/j.smim.2013.10.004. Epub 2013 Nov 23.

PMID:
24275599
30.

Cholesteryl ester storage disease: an easily missed diagnosis in oligosymptomatic children.

Freudenberg F, Bufler P, Ensenauer R, Lohse P, Koletzko S.

Z Gastroenterol. 2013 Oct;51(10):1184-7. doi: 10.1055/s-0033-1350463. Epub 2013 Oct 11.

PMID:
24122380
31.

Analysis of nuclear localization of interleukin-1 family cytokines by flow cytometry.

Ross R, Grimmel J, Goedicke S, Möbus AM, Bulau AM, Bufler P, Ali S, Martin MU.

J Immunol Methods. 2013 Jan 31;387(1-2):219-27. doi: 10.1016/j.jim.2012.10.017. Epub 2012 Nov 13.

PMID:
23159404
32.

[S3-Consensus guidelines on definition, etiology, diagnosis and medical, endoscopic and surgical management of chronic pancreatitis German Society of Digestive and Metabolic Diseases (DGVS)].

Chronic Pancreatitis German Society of Digestive and Metabolic Diseases (DGVS), Hoffmeister A, Mayerle J, Beglinger C, Büchler MW, Bufler P, Dathe K, Fölsch UR, Friess H, Izbicki J, Kahl S, Klar E, Keller J, Knoefel WT, Layer P, Loehr M, Meier R, Riemann JF, Rünzi M, Schmid RM, Schreyer A, Tribl B, Werner J, Witt H, Mössner J, Lerch MM.

Z Gastroenterol. 2012 Nov;50(11):1176-224. doi: 10.1055/s-0032-1325479. Epub 2012 Nov 13. German. No abstract available.

PMID:
23150111
33.

In vivo expression of interleukin-37 reduces local and systemic inflammation in concanavalin A-induced hepatitis.

Bulau AM, Fink M, Maucksch C, Kappler R, Mayr D, Wagner K, Bufler P.

ScientificWorldJournal. 2011;11:2480-90. doi: 10.1100/2011/968479. Epub 2011 Dec 26.

34.

IL-37: a new anti-inflammatory cytokine of the IL-1 family.

Boraschi D, Lucchesi D, Hainzl S, Leitner M, Maier E, Mangelberger D, Oostingh GJ, Pfaller T, Pixner C, Posselt G, Italiani P, Nold MF, Nold-Petry CA, Bufler P, Dinarello CA.

Eur Cytokine Netw. 2011 Sep;22(3):127-47. doi: 10.1684/ecn.2011.0288. Review.

35.

Interleukin 37 expression protects mice from colitis.

McNamee EN, Masterson JC, Jedlicka P, McManus M, Grenz A, Collins CB, Nold MF, Nold-Petry C, Bufler P, Dinarello CA, Rivera-Nieves J.

Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16711-6. doi: 10.1073/pnas.1111982108. Epub 2011 Aug 22.

36.

Recurrent abdominal pain in childhood.

Bufler P, Gross M, Uhlig HH.

Dtsch Arztebl Int. 2011 Apr;108(17):295-304. doi: 10.3238/arztebl.2011.0295. Epub 2011 Apr 29. Review.

37.

Long-term development of bone geometry and muscle in pediatric inflammatory bowel disease.

Werkstetter KJ, Pozza SB, Filipiak-Pittroff B, Schatz SB, Prell C, Bufler P, Koletzko B, Koletzko S.

Am J Gastroenterol. 2011 May;106(5):988-98. doi: 10.1038/ajg.2010.495. Epub 2011 Jan 11.

PMID:
21224841
38.

IL-1 family nomenclature.

Dinarello C, Arend W, Sims J, Smith D, Blumberg H, O'Neill L, Goldbach-Mansky R, Pizarro T, Hoffman H, Bufler P, Nold M, Ghezzi P, Mantovani A, Garlanda C, Boraschi D, Rubartelli A, Netea M, van der Meer J, Joosten L, Mandrup-Poulsen T, Donath M, Lewis E, Pfeilschifter J, Martin M, Kracht M, Muehl H, Novick D, Lukic M, Conti B, Solinger A, Kelk P, van de Veerdonk F, Gabel C.

Nat Immunol. 2010 Nov;11(11):973. doi: 10.1038/ni1110-973. No abstract available. Erratum in: Nat Immunol. 2011 Mar;12(3):271. Peyman, Kelk [corrected to Kelk, Peyman].

39.

IL-37 is a fundamental inhibitor of innate immunity.

Nold MF, Nold-Petry CA, Zepp JA, Palmer BE, Bufler P, Dinarello CA.

Nat Immunol. 2010 Nov;11(11):1014-22. doi: 10.1038/ni.1944. Epub 2010 Oct 10.

40.

Expression, regulation and clinical significance of soluble and membrane CD14 receptors in pediatric inflammatory lung diseases.

Marcos V, Latzin P, Hector A, Sonanini S, Hoffmann F, Lacher M, Koller B, Bufler P, Nicolai T, Hartl D, Griese M.

Respir Res. 2010 Mar 19;11:32. doi: 10.1186/1465-9921-11-32.

41.

The feasibility of wireless capsule endoscopy in detecting small intestinal pathology in children under the age of 8 years: a multicentre European study.

Fritscher-Ravens A, Scherbakov P, Bufler P, Torroni F, Ruuska T, Nuutinen H, Thomson M, Tabbers M, Milla P.

Gut. 2009 Nov;58(11):1467-72. doi: 10.1136/gut.2009.177774. Epub 2009 Jul 21.

PMID:
19625281
42.

Nuclear pregnane X receptor single nucleotide polymorphism (-25385C/T) is not associated with inflammatory bowel disease in pediatric patients.

Lacher M, Kappler R, Schroepf S, Berkholz S, Ballauff A, Bufler P, Baurecht H, von Schweinitz D, Koletzko S.

J Pediatr Gastroenterol Nutr. 2009 Jul;49(1):147-50. doi: 10.1097/MPG.0b013e31818de1a8.

PMID:
19516190
43.

Influence of age and genetic risk on anti-tissue transglutaminase IgA titers.

Vécsei A, Arenz T, Heilig G, Arenz S, Bufler P, Koletzko S.

J Pediatr Gastroenterol Nutr. 2009 May;48(5):544-9. doi: 10.1097/MPG.0b013e31818c5ff6.

PMID:
19367177
44.

The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines.

Sharma S, Kulk N, Nold MF, Gräf R, Kim SH, Reinhardt D, Dinarello CA, Bufler P.

J Immunol. 2008 Apr 15;180(8):5477-82.

45.

A pilot study of cytokine levels and white blood cell counts in the diagnosis of necrotizing fasciitis.

Rodriguez RM, Abdullah R, Miller R, Barry L, Lungstras-Bufler K, Bufler P, Dinarello CA, Abraham E.

Am J Emerg Med. 2006 Jan;24(1):58-61.

PMID:
16338511
46.

High cytokine levels at admission are associated with fatal outcome in patients with necrotizing fasciitis.

Lungstras-Bufler K, Bufler P, Abdullah R, Rutherford C, Endres S, Abraham E, Dinarello CA, Rodriguez RM.

Eur Cytokine Netw. 2004 Apr-Jun;15(2):135-8.

47.

Cytokine stimulation by Pseudomonas aeruginosa--strain variation and modulation by pulmonary surfactant.

Bufler P, Schikor D, Schmidt B, Griese M.

Exp Lung Res. 2004 Apr-May;30(3):163-79.

PMID:
15195551
48.

Effect of advanced glycation end products on endotoxin-induced TNF-alpha, IL-1beta and IL-8 in human peripheral blood mononuclear cells.

Reznikov LL, Waksman J, Azam T, Kim SH, Bufler P, Niwa T, Werman A, Zhang X, Pischetsrieder M, Shaldon S, Dinarello CA.

Clin Nephrol. 2004 May;61(5):324-36.

PMID:
15182127
49.
50.

Identification of a critical Ig-like domain in IL-18 receptor alpha and characterization of a functional IL-18 receptor complex.

Azam T, Novick D, Bufler P, Yoon DY, Rubinstein M, Dinarello CA, Kim SH.

J Immunol. 2003 Dec 15;171(12):6574-80.

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